070202-粒子物理与原子核物理

核医学成像
神经成像

2015-09--2020-06   中国科学院大学   博士
2011-09--2015-06   中国科学技术大学   学士

   

2023-01~现在, 中国科学院高能物理研究所, 副研究员
2022-07~2023-01,中国科学院高能物理研究所, 助理研究员
2020-07~2022-06,中国科学院高能物理研究所, 博士后

（1） Unified spatial normalization method of brain PET images using adaptive probabilistic brain atlas, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022

（2） Modular architecture of metabolic brain network and its effects on the spread of perturbation impact, NEUROIMAGE, 2019

（3） Simultaneous PET-MRI imaging of cerebral blood flow and glucose metabolism in the symptomatic unilateral internal carotid artery/middle cerebral artery steno-occlusive disease, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020

[1] Zhao, Shilun, Zhang, Tianhao, Zhang, Wei, Pan, Tingting, Zhang, Ge, Feng, Shuang, Zhang, Xiwan, Nie, Binbin, Liu, Hua, Shan, Baoci, Alzheimers Dis Neuroimaging. Harmonizing T1-Weighted Images to Improve Consistency of Brain Morphology Among Different Scanner Manufacturers in Alzheimer's disease. JOURNAL OF MAGNETIC RESONANCE IMAGING[J]. 2023, http://dx.doi.org/10.1002/jmri.28887.
[2] Huang, Qi, Ren, Shuhua, Zhang, Tianhao, Li, Junpeng, Jiang, Donglang, Xiao, Jianfei, Hua, Fengchun, Xie, Fang, Guan, Yihui. Aging-Related Modular Architectural Reorganization of the Metabolic Brain Network. BRAIN CONNECTIVITY[J]. 2022, 12(5): 432-442, http://dx.doi.org/10.1089/brain.2021.0054.
[3] Cheng, Yuqi, Wang, Ting, Zhang, Tianhao, Yi, Shu, Zhao, Shilun, Li, Na, Yang, Yifan, Zhang, Fengrui, Xu, Lin, Shan, Baoci, Xu, Xiufeng, Xu, Jian. Increased Blood-Brain Barrier Permeability of the Thalamus Correlated With Symptom Severity and Brain Volume Alterations in Patients With Schizophrenia. BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING[J]. 2022, 7(10): 1025-1034, http://dx.doi.org/10.1016/j.bpsc.2022.06.006.
[4] Zhang, Tianhao, Nie, Binbin, Liu, Hua, Shan, BaoCi. Unified spatial normalization method of brain PET images using adaptive probabilistic brain atlas. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING[J]. 2022, 49(9): 3073-3085, http://dx.doi.org/10.1007/s00259-022-05752-6.
[5] Bao, Zhiguo, Zhang, Tianhao, Pan, Tingting, Zhang, Wei, Zhao, Shilun, Liu, Hua, Nie, Binbin. Automatic method for individual parcellation of manganese-enhanced magnetic resonance imaging of rat brain. FRONTIERS IN NEUROSCIENCE[J]. 2022, 16: http://dx.doi.org/10.3389/fnins.2022.954237.
[6] Cui, Bixiao, Shan, Yi, Zhang, Tianhao, Ma, Yan, Yang, Bin, Yang, Hongwei, Jiao, Liqun, Shan, Baoci, Lu, Jie. Crossed cerebellar diaschisis-related supratentorial hemodynamic and metabolic status measured by PET/MR in assessing postoperative prognosis in chronic ischemic cerebrovascular disease patients with bypass surgery. ANNALS OF NUCLEAR MEDICINE[J]. 2022, 36(9): 812-822, http://dx.doi.org/10.1007/s12149-022-01766-0.
[7] Pan, TingTing, Liu, Chao, Li, DeMin, Zhang, TianHao, Zhang, Wei, Zhao, ShiLun, Zhou, QiXin, Nie, BinBin, Zhu, GaoHong, Xu, Lin, Liu, Hua. Retrosplenial Cortex Effects Contextual Fear Formation Relying on Dysgranular Constituent in Rats. FRONTIERS IN NEUROSCIENCE[J]. 2022, 16: http://dx.doi.org/10.3389/fnins.2022.886858.
[8] TingTing Pan, Chao Liu, DeMin Li, BinBin Nie, TianHao Zhang, Wei Zhang, ShiLun Zhao, QiXin Zhou, Hua Liu, GaoHong Zhu, Lin Xu, Shan，BaoCi. Nucleus accumbens-linked executive control networks mediating reversal learning in tree shrew brain. 动物学研究[J]. 2022, 43(4): 528-531, http://lib.cqvip.com/Qikan/Article/Detail?id=7107719547.
[9] Zhang, Wei, Zhang, Tianhao, Pan, Tingting, Zhao, Shilun, Nie, Binbin, Liu, Hua, Shan, Baoci. Deep Learning With 18F-Fluorodeoxyglucose-PET Gives Valid Diagnoses for the Uncertain Cases in Memory Impairment of Alzheimer's Disease. FRONTIERSINAGINGNEUROSCIENCE[J]. 2021, 13: http://dx.doi.org/10.3389/fnagi.2021.764272.
[10] Zhang, Tianhao, Zhao, Bingcong, Shi, Chuan, Nie, Binbin, Liu, Hua, Yang, Xinjing, Sun, Yang, Li, Panlong, Lin, Lei, Yang, Xiuyan, Li, Jing, Gao, Xingzhou, Feng, Shixing, Li, Xiang, Sun, Xi, Pan, Tingting, Feng, Ting, Bao, Tuya, Shan, Baoci. Subthreshold depression may exist on a spectrum with major depressive disorder: Evidence from gray matter volume and morphological brain network. JOURNAL OF AFFECTIVE DISORDERS[J]. 2020, 266: 243-251, http://dx.doi.org/10.1016/j.jad.2020.01.135.
[11] Sun, Xi, Nie, Binbin, Zhao, Shujun, Ai, Lin, Chen, Qian, Zhang, Tianhao, Pan, Tingting, Wang, Luying, Yin, Xiaolong, Zhang, Wei, Shan, Baoci, Liu, Hua, Liang, Shengxiang, Wang, Guihong. Distinct relationships of amyloid-beta and tau deposition to cerebral glucose metabolic networks in Alzheimer's disease. NEUROSCIENCE LETTERS[J]. 2020, 717: http://dx.doi.org/10.1016/j.neulet.2019.134699.
[12] Cui, Bixiao, Zhang, Tianhao, Ma, Yan, Chen, Zhongwei, Ma, Jie, Ma, Lei, Jiao, Liqun, Zhou, Yun, Shan, Baoci, Lu, Jie. Simultaneous PET-MRI imaging of cerebral blood flow and glucose metabolism in the symptomatic unilateral internal carotid artery/middle cerebral artery steno-occlusive disease. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING[J]. 2020, 47(7): 1668-1677, https://www.webofscience.com/wos/woscc/full-record/WOS:000494783700001.
[13] 张天昊. 基于FDG-PET的脑代谢数据处理方法及其在脑缺血病中的应用. 2020, [14] Huang, Qi, Zhang, Jian, Zhang, Tianhao, Wang, Hui, Yan, Jianhua. Age-associated reorganization of metabolic brain connectivity in Chinese children. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING[J]. 2020, 47(2): 235-246, http://dx.doi.org/10.1007/s00259-019-04508-z.
[15] Li, Mingge, Liu, Tiefang, Zhang, Tianhao, Chen, Zhiye, Nie, Binbin, Lou, Xin, Wang, Zhenfu, Ma, Lin. Alterations of regional homogeneity in Parkinson's disease with mild cognitive impairment: a preliminary resting-state fMRI study. NEURORADIOLOGY[J]. 2020, 62(3): 327-334, https://www.webofscience.com/wos/woscc/full-record/WOS:000516566100008.
[16] Nie, Binbin, Wu, Di, Liang, Shengxiang, Liu, Hua, Sun, Xi, Li, Panlong, Huang, Qi, Zhang, Tianhao, Feng, Ting, Ye, Songtao, Zhang, Zhijun, Shan, Baoci. A stereotaxic MRI template set of mouse brain with fine sub-anatomical delineations: Application to MEMRI studies of 5XFAD mice. MAGNETIC RESONANCE IMAGING[J]. 2019, 57: 83-94, http://dx.doi.org/10.1016/j.mri.2018.10.014.
[17] Sun, Xi, Zhao, Shujun, Liang, Shengxiang, Feng, Ting, Li, Panlong, Zhang, Tianhao, Huang, Qi, Liu, Hua, Nie, Binbin, Shan, Baoci. The negative correlation between energy consumption and communication efficiency in motor network. NUCLEAR MEDICINE COMMUNICATIONS[J]. 2019, 40(5): 499-507, [18] Sun, Xi, Nie, Binbin, Zhao, Shujun, Chen, Qian, Li, Panlong, Zhang, Tianhao, Pan, Tingting, Feng, Ting, Wang, Luying, Yin, Xiaolong, Zhang, Wei, Zhao, Shilun, Shan, Baoci, Liu, Hua, Liang, Shengxiang, Ai, Lin, Wang, Guihong. Tau PET Distributional Pattern in AD Patients with Visuospatial Dysfunction. CURRENT ALZHEIMER RESEARCH[J]. 2019, 16(11): 1055-1062, [19] Shan, Han, Li, Panlong, Liu, Hua, Nie, Binbin, Yin, Xiaolong, Zhang, Tianhao, Sun, Xi, Zhang, Wei, Feng, Ting, Wang, Luying, Hu, Yichao, Dong, Guanglong, Gao, Hongkai, Du, Jin, Ma, Lin, Li, Demin, Shan, Baoci. Gray matter reduction related to decreased serum creatinine and increased triglyceride, Hemoglobin A1C, and low-density lipoprotein in subjects with obesity. NEURORADIOLOGY[J]. 2019, 61(6): 703-710, https://www.webofscience.com/wos/woscc/full-record/WOS:000467659100010.
[20] Sun, Xi, Liang, Shengxiang, Fu, Liping, Zhang, Xiaojun, Feng, Ting, Li, Panlong, Zhang, Tianhao, Wang, Luying, Yin, Xiaolong, Zhang, Wei, Hu, Yichao, Liu, Hua, Zhao, Shujun, Nie, Binbin, Xu, Baixuan, Shan, Baoci. A human brain tau PET template in MNI space for the voxel-wise analysis of Alzheimer's disease. JOURNAL OF NEUROSCIENCE METHODS[J]. 2019, 328: http://dx.doi.org/10.1016/j.jneumeth.2019.108438.
[21] Zhang, Tianhao, Huang, Qi, Jiao, Chunxiang, Liu, Hua, Nie, Binbin, Liang, Shengxiang, Li, Panlong, Sun, Xi, Feng, Ting, Xu, Lin, Shan, Baoci. Modular architecture of metabolic brain network and its effects on the spread of perturbation impact. NEUROIMAGE[J]. 2019, 186: 146-154, http://dx.doi.org/10.1016/j.neuroimage.2018.11.003.
[22] Li, Panlong, Shan, Han, Liang, Shengxiang, Nie, Binbin, Duan, Shaofeng, Huang, Qi, Zhang, Tianhao, Sun, Xi, Feng, Ting, Ma, Lin, Shan, Baoci, Li, Demin, Liu, Hua. Structural and functional brain network of human retrosplenial cortex. NEUROSCIENCE LETTERS[J]. 2018, 674: 24-29, http://www.corc.org.cn/handle/1471x/2177601.
[23] Liang, Shengxiang, Jiang, Xiaofeng, Zhang, Qingqing, Duan, Shaofeng, Zhang, Tianhao, Huang, Qi, Sun, Xi, Liu, Hua, Dong, Jie, Liu, Weilin, Tao, Jing, Zhao, Shujun, Nie, Binbin, Chen, Lidian, Shan, Baoci. Abnormal Metabolic Connectivity in Rats at the Acute Stage of Ischemic Stroke. NEUROSCIENCE BULLETIN[J]. 2018, 34(5): 715-724, http://lib.cqvip.com/Qikan/Article/Detail?id=676513941.
[24] Nie, Binbin, Liang, Shengxiang, Jiang, Xiaofeng, Duan, Shaofeng, Huang, Qi, Zhang, Tianhao, Li, Panlong, Liu, Hua, Shan, Baoci. An Automatic Method for Generating an Unbiased Intensity Normalizing Factor in Positron Emission Tomography Image Analysis After Stroke. NEUROSCIENCE BULLETIN[J]. 2018, 34(5): 833-841, http://lib.cqvip.com/Qikan/Article/Detail?id=676513952.
[25] Li, Panlong, Shan, Han, Liang, Shengxiang, Nie, Binbin, Liu, Hua, Duan, Shaofeng, Huang, Qi, Zhang, Tianhao, Dong, Guanglong, Guo, Yulin, Du, Jin, Gao, Hongkai, Ma, Lin, Li, Demin, Shan, Baoci. Sleeve Gastrectomy Recovering Disordered Brain Function in Subjects with Obesity: a Longitudinal fMRI Study. OBESITYSURGERY[J]. 2018, 28(8): 2421-2428, http://dx.doi.org/10.1007/s11695-018-3178-z.
[26] Huang, Qi, Nie, Binbin, Ma, Chen, Wang, Jing, Zhang, Tianhao, Duan, Shaofeng, Wu, Shang, Liang, Shengxiang, Li, Panlong, Liu, Hua, Sun, Hua, Zhou, Jiangning, Xu, Lin, Shan, Baoci. Stereotaxic F-18-FDG PET and MRI templates with three-dimensional digital atlas for statistical parametric mapping analysis of tree shrew brain. JOURNAL OF NEUROSCIENCE METHODS[J]. 2018, 293: 105-116, http://www.corc.org.cn/handle/1471x/2177835.
[27] Binbin Nie, Shengxiang Liang, Xiaofeng Jiang, Shaofeng Duan, Qi Huang, Tianhao Zhang, Panlong Li, Hua Liu, Baoci Shan. An Automatic Method for Generating an Unbiased Intensity Normalizing Factor in Positron Emission Tomography Image Analysis After Stroke. 神经科学通报：英文版[J]. 2018, 34(5): 833-841, http://lib.cqvip.com/Qikan/Article/Detail?id=676513952.
[28] Qi Huang, Binbin Nie, Chen Ma, Jing Wang, Tianhao Zhang, Shaofeng Duan, Shang Wu, Shengxiang Liang, Panlong Li, Hua Liu, Hua Sun, Jiangning Zhou, Lin Xu, Baoci Shan. Stereotaxic 18F-FDG PET and MRI templates with three-dimensional digital atlas for statistical parametric mapping analysis of tree shrew brain. JOURNAL OF NEUROSCIENCE METHODS. 2018, 293: 105-116, http://dx.doi.org/10.1016/j.jneumeth.2017.09.006.
[29] Shengxiang Liang, Xiaofeng Jiang, Qingqing Zhang, Shaofeng Duan, Tianhao Zhang, Qi Huang, Xi Sun, Hua Liu, Jie Dong, Weilin Liu, Jing Tao, Shujun Zhao, Binbin Nie, Lidian Chens, Baoci Shan. Abnormal Metabolic Connectivity in Rats at the Acute Stage of Ischemic Stroke. 神经科学通报：英文版[J]. 2018, 34(5): 715-724, http://lib.cqvip.com/Qikan/Article/Detail?id=676513941.

   

（ 1 ） 多中心PET脑成像数据校正方法研究, 负责人, 国家任务, 2023-01--2025-12
（ 2 ） 多探针PET脑成像数据联合分析方法的研究及软件平台的建立, 参与, 国家任务, 2022-01--2025-12
（ 3 ） 基于动态FDGPET的个体脑代谢网络的建立方法及其应用, 负责人, 国家任务, 2021-06--2022-06
（ 4 ） 多模态PET/MRI脑成像联合处理方法研究, 参与, 国家任务, 2020-01--2023-12
（ 5 ） 多中心脑结构磁共振成像数据校正方法的研究, 参与, 国家任务, 2018-01--2021-12

现指导学生

毛广娟  博士研究生  070202-粒子物理与原子核物理