070303-有机化学
100701-药物化学
071010-生物化学与分子生物学

天然药物化学；金属有机催化；光氧化还原催化

2010-09--2016-01   中国科学院兰州化学物理研究所   硕博连读

   

2019-09~2022-08,深圳湾实验室, 助理研究员
2017-08~2019-08,香港理工大学, 博士后
2010-09~2016-01,中国科学院兰州化学物理研究所, 硕博连读

有机化学

   

（1） 深圳先进技术研究院优秀青年, 一等奖, 研究所（学校）, 2023
（2） 深圳湾实验室2021年度优秀员工, 一等奖, 研究所（学校）, 2022
（3） 深圳市海外高层次人才C类, 二等奖, 市地级, 2020

（ 1 ） 穿心莲内酯类化合物及其制备方法、药物组合物和其在抗肿瘤药物中的应用, 2022, 第 4 作者, 专利号: CN111518085B

（ 2 ） 氮杂螺环、多环穿心莲内酯类化合物及其制备方法、药物组合物及其应用, 2021, 第 2 作者, 专利号: CN112645937A

   

（1） Thermal- and oxidation dual-responsive random copolymer self-assembly of nanostructures., Polym. Chem., 2024, 
（2） Amphiphilic Block Copolymers Containing Benzenesulfonyl Azide Groups as Visible Light-Responsive Drug Carriers for Image-Guided Delivery., Biomacromolecules, 2024, 
（3） Investigating AIE behaviors of amphiphilic AIEgen based polymers through self-assembly architectures and hydrophobic core arrangements., Polym. Chem., 2023, 
（4） Visible-Light-Promoted C(sp3)���C(sp3) Cross-Coupling of Amino Acids and Aryl Trifluoromethyl Ketones Through Simultaneous Decarboxylation and Defluorination., Organic Letters, 2023, 
（5） Combining visible-light induction and copper catalysis for chemo-selective nitrene transfer for late-stage amination of natural products, COMMUNICATIONS CHEMISTRY, 2022, 第 11 作者
（6） Tumor-Targeting Polymer-Drug Conjugate for Liver Cancer Treatment In Vitro, POLYMERS, 2022, 第 11 作者
（7） Enhancing stability by trapping palladium inside N-heterocyclic carbene-functionalized hypercrosslinked polymers for heterogeneous C-C bond formations, NATURE COMMUNICATIONS, 2021, 第 2 作者
（8） Photoredox Decarboxylative C(sp3 )���N Coupling of �����Diazoacetates with Alkyl N���Hydroxyphthalimide Esters for Diversified Synthesis of Functionalized N���Alkyl Hydrazones, Organic Letters, 2019, 第 2 作者
（9） Ruthenium(II)-Catalyzed Enantioselective �����Lactams Formation by Intramolecular C���H Amidation of 1,4,2-Dioxazol-5-ones, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 第 1 作者
（10） Palladium-catalyzed intermolecular carbonylative cross-coupling of heteroaryl C(sp(2))-H bonds with amines: an efficient strategy for oxidative aminocarbonylation of azoles, CHEMICAL COMMUNICATIONS, 2017, 第 1 作者
（11） W Iron-catalyzed aerobic oxidative cleavage of the C-C sigma-bond using air as the oxidant: chemoselective synthesis of carbon chain-shortened aldehydes, ketones and 1,2-dicarbonyl compounds, CHEMICAL COMMUNICATIONS, 2016, 第 1 作者
（12） Iron-catalyzed aerobic oxidative cleavage of the C-C sigma-bond using air as the oxidant: chemoselective synthesis of carbon chain-shortened aldehydes, ketones and 1,2-dicarbonyl compounds, CHEMICAL COMMUNICATIONS, 2016, 第 1 作者
（13） Intramolecular Cooperative C-C Bond Cleavage Reaction of 1,3-Dicarbonyl Compounds with 2-Iodoanilines to Give o-(N-Acylamino)aryl Ketones and Multisubstituted Indoles, CHEMISTRY-A EUROPEAN JOURNAL, 2015, 第 1 作者
（14） Acid-catalyzed acylation reaction via C-C bond cleavage: a facile and mechanistically defined approach to synthesize 3-acylindoles, CHEMICAL COMMUNICATIONS, 2014, 第 1 作者
（15） Palladium-catalyzed mono- and double-carbonylation of indoles with amines controllably leading to amides and alpha-ketoamides, CHEMICAL COMMUNICATIONS, 2012, 第 1 作者

Synthesis of Functionalized Heterocycles via Oxidative Carbonylation, Springer International Publishing Switzerland, 2015-07, 第 1 作者

   

（ 1 ） 中国科学院先进技术研究院2022年度优秀青年创新基金项目, 负责人, 研究所自主部署, 2023-01--2024-12