基本信息
汪习 男 硕导 中国科学院武汉病毒研究所
电子邮件： wangxi@wh.iov.cn
通信地址： 湖北省武汉市江夏区郑店街道黄金工业园金龙大街262号
邮政编码：
电子邮件： wangxi@wh.iov.cn
通信地址： 湖北省武汉市江夏区郑店街道黄金工业园金龙大街262号
邮政编码：
招生信息
招生专业
071005-微生物学
071010-生物化学与分子生物学
071010-生物化学与分子生物学
招生方向
抗病毒药物研发
病毒入侵机制
病毒入侵机制
教育背景
2011-09--2019-06 中国科学院武汉病毒研究所 博士学位
2006-09--2010-07 新疆大学 学士学位
2006-09--2010-07 新疆大学 学士学位
工作经历
工作简历
2022-11~现在, 中国科学院武汉病毒研究所, 副研究员
2022-01~2022-10,中国科学院武汉病毒研究所, 助理研究员
2019-12~2021-12,中国科学院武汉病毒研究所, 博士后
2011-09~2019-06,中国科学院武汉病毒研究所, 博士学位
2006-09~2010-07,新疆大学, 学士学位
2022-01~2022-10,中国科学院武汉病毒研究所, 助理研究员
2019-12~2021-12,中国科学院武汉病毒研究所, 博士后
2011-09~2019-06,中国科学院武汉病毒研究所, 博士学位
2006-09~2010-07,新疆大学, 学士学位
出版信息
发表论文
（1） AcMNPV P74 is cleaved at R325 and R334 by proteinases of both OB and BBMV to expose a potential fusion peptide for oral infection, Journal of Virology, 2024, 第 8 作者 通讯作者
（2） Antiviral effects and tissue exposure of tetrandrine against SARS���CoV���2 infection and COVID���19, MEDCOMM, 2023,
（3） Novel Tetrahydroisoquinoline-Based Heterocyclic Compounds Efficiently Inhibit SARS-CoV-2 Infection In Vitro, VIRUSES, 2023,
（4） Hybridoma-derived neutralizing monoclonal antibodies against Beta and Delta variants of SARS-CoV-2 in vivo, Hybridoma-derived neutralizing monoclonal antibodies against Beta and Delta variants of SARS-CoV-2 in vivo, VIROLOGICA SINICA, 2023,
（5） Atlas of interactions between SARS-CoV-2 macromolecules and host proteins, CELL INSIGHT, 2022,
（6） Genomics and proteomics of Apis mellifera filamentous virus isolated from honeybees in China, VIROLOGICA SINICA, 2022,
（7） Empirical estimates of the mutation rate for an alphabaculovirus (vol 18, e1009806, 2022), PLOS GENETICS, 2022,
（8） Structural Characterization of Per Os Infectivity Factor 5 (PIF5) Reveals the Essential Role of Intramolecular Interactions in Baculoviral Oral Infectivity, JOURNAL OF VIROLOGY, 2022,
（9） Functional Peroral Infectivity Complex of White Spot Syndrome Virus of Shrimp, JOURNAL OF VIROLOGY, 2022,
（10） SARS-CoV-2 cell tropism and multiorgan infection, CELL DISCOVERY, 2021,
（11） Construction and Characterization of a Novel Bacmid AcBac-Syn Based on a Synthesized Baculovirus Genome, Construction and Characterization of a Novel Bacmid AcBac-Syn Based on a Synthesized Baculovirus Genome, VIROLOGICA SINICA, 2021,
（12） Infection of human sweat glands by SARS-CoV-2, CELL DISCOVERY, 2020,
（13） Anti-SARS-CoV-2 Potential of Artemisinins InVitro, ACS INFECTIOUS DISEASES, 2020,
（14） The anti-influenza virus drug, arbidol is an efficient inhibitor of SARS-CoV-2 in vitro, CELL DISCOVERY, 2020,
（15） Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro, Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro, VIROLOGICA SINICA, 2020,
（16） Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro, Cell Discovery, 2020,
（17） Genomic and transcriptional analyses of novel parvoviruses identified from dead peafowl, VIROLOGY, 2020,
（18） Baculovirus Per Os Infectivity Factor Complex: Components and Assembly, JOURNAL OF VIROLOGY, 2019,
（19） The cysteine-rich region of a baculovirus VP91 protein contributes to the morphogenesis of occlusion bodies, VIROLOGY, 2019,
（20） The group i alphabaculovirus-specific protein, ac5, is a novel component of the occlusion body but is not associated with odvs or the pif complex, JOURNAL OF GENERAL VIROLOGY, 2018,
（21） HearNPV Pseudotyped with PIF1,2,and 3 from MabrNPV:Infectivity and Complex Stability, HearNPV Pseudotyped with PIF1, 2, and 3 from MabrNPV: Infectivity and Complex Stability, VIROLOGICA SINICA, 2018,
（22） Construction and rescue of a functional synthetic baculovirus, ACS SYNTHETIC BIOLOGY, 2017,
（23） 口服感染因子：杆状病毒编码的一种复杂而进化保守的入侵机器, Per os infectivity factors: a complicated and evolutionarily conserved entry machinery of baculovirus, 中国科学（生命科学）, 2017, 第 1 作者
（24） Inhibition of Melanization by Serpin-5 and Serpin-9 Promotes Baculovirus Infection in Cotton Bollworm Helicoverpa armigera, PLOS PATHOGENS, 2017,
（25） Per os infectivity factors: a complicated and evolutionarily conserved entry machinery of baculovirus, SCIENCE CHINA-LIFE SCIENCES, 2017,
（26） The Host Specificities of Baculovirus per os Infectivity Factors, PLOS ONE, 2016,
（2） Antiviral effects and tissue exposure of tetrandrine against SARS���CoV���2 infection and COVID���19, MEDCOMM, 2023,
（3） Novel Tetrahydroisoquinoline-Based Heterocyclic Compounds Efficiently Inhibit SARS-CoV-2 Infection In Vitro, VIRUSES, 2023,
（4） Hybridoma-derived neutralizing monoclonal antibodies against Beta and Delta variants of SARS-CoV-2 in vivo, Hybridoma-derived neutralizing monoclonal antibodies against Beta and Delta variants of SARS-CoV-2 in vivo, VIROLOGICA SINICA, 2023,
（5） Atlas of interactions between SARS-CoV-2 macromolecules and host proteins, CELL INSIGHT, 2022,
（6） Genomics and proteomics of Apis mellifera filamentous virus isolated from honeybees in China, VIROLOGICA SINICA, 2022,
（7） Empirical estimates of the mutation rate for an alphabaculovirus (vol 18, e1009806, 2022), PLOS GENETICS, 2022,
（8） Structural Characterization of Per Os Infectivity Factor 5 (PIF5) Reveals the Essential Role of Intramolecular Interactions in Baculoviral Oral Infectivity, JOURNAL OF VIROLOGY, 2022,
（9） Functional Peroral Infectivity Complex of White Spot Syndrome Virus of Shrimp, JOURNAL OF VIROLOGY, 2022,
（10） SARS-CoV-2 cell tropism and multiorgan infection, CELL DISCOVERY, 2021,
（11） Construction and Characterization of a Novel Bacmid AcBac-Syn Based on a Synthesized Baculovirus Genome, Construction and Characterization of a Novel Bacmid AcBac-Syn Based on a Synthesized Baculovirus Genome, VIROLOGICA SINICA, 2021,
（12） Infection of human sweat glands by SARS-CoV-2, CELL DISCOVERY, 2020,
（13） Anti-SARS-CoV-2 Potential of Artemisinins InVitro, ACS INFECTIOUS DISEASES, 2020,
（14） The anti-influenza virus drug, arbidol is an efficient inhibitor of SARS-CoV-2 in vitro, CELL DISCOVERY, 2020,
（15） Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro, Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro, VIROLOGICA SINICA, 2020,
（16） Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro, Cell Discovery, 2020,
（17） Genomic and transcriptional analyses of novel parvoviruses identified from dead peafowl, VIROLOGY, 2020,
（18） Baculovirus Per Os Infectivity Factor Complex: Components and Assembly, JOURNAL OF VIROLOGY, 2019,
（19） The cysteine-rich region of a baculovirus VP91 protein contributes to the morphogenesis of occlusion bodies, VIROLOGY, 2019,
（20） The group i alphabaculovirus-specific protein, ac5, is a novel component of the occlusion body but is not associated with odvs or the pif complex, JOURNAL OF GENERAL VIROLOGY, 2018,
（21） HearNPV Pseudotyped with PIF1,2,and 3 from MabrNPV:Infectivity and Complex Stability, HearNPV Pseudotyped with PIF1, 2, and 3 from MabrNPV: Infectivity and Complex Stability, VIROLOGICA SINICA, 2018,
（22） Construction and rescue of a functional synthetic baculovirus, ACS SYNTHETIC BIOLOGY, 2017,
（23） 口服感染因子：杆状病毒编码的一种复杂而进化保守的入侵机器, Per os infectivity factors: a complicated and evolutionarily conserved entry machinery of baculovirus, 中国科学（生命科学）, 2017, 第 1 作者
（24） Inhibition of Melanization by Serpin-5 and Serpin-9 Promotes Baculovirus Infection in Cotton Bollworm Helicoverpa armigera, PLOS PATHOGENS, 2017,
（25） Per os infectivity factors: a complicated and evolutionarily conserved entry machinery of baculovirus, SCIENCE CHINA-LIFE SCIENCES, 2017,
（26） The Host Specificities of Baculovirus per os Infectivity Factors, PLOS ONE, 2016,
科研活动
科研项目
（ 1 ） CCHFV的致病机理及抗病毒药物研究, 参与, 国家任务, 2023-01--2026-12
（ 2 ） 对虾白斑综合症病毒PIF复合物的组成和功能研究, 负责人, 国家任务, 2021-01--2023-12
（ 2 ） 对虾白斑综合症病毒PIF复合物的组成和功能研究, 负责人, 国家任务, 2021-01--2023-12