基本信息
原子皓 男 中国科学院海洋研究所
电子邮件： yuanzihao@qdio.ac.cn
通信地址： 青岛市市南区南海路7号
邮政编码：
电子邮件： yuanzihao@qdio.ac.cn
通信地址： 青岛市市南区南海路7号
邮政编码：
招生信息
招生专业
070703-海洋生物学
招生方向
进化生物学
教育背景
2014-08--2018-05 Auburn University 博士
2010-09--2014-07 中国海洋大学 学士
2010-09--2014-07 中国海洋大学 学士
工作经历
工作简历
2023-01~现在, 中国科学院海洋研究所, 副研究员
2020-12~2022-12,中国科学院海洋研究所, 特别研究助理
2018-06~2020-11,UTHealth Houston, postdoctorate
2014-08~2018-05,Auburn University, 博士
2010-09~2014-07,中国海洋大学, 学士
2020-12~2022-12,中国科学院海洋研究所, 特别研究助理
2018-06~2020-11,UTHealth Houston, postdoctorate
2014-08~2018-05,Auburn University, 博士
2010-09~2014-07,中国海洋大学, 学士
社会兼职
2022-05-01-2023-12-31,Guest Editor for Special Issue in Frontiers in Immunology, Guest Editor
2022-01-01-今,Guest Editor for Special Issue in Genes, Guest Editor
2022-01-01-2022-12-31,Guest Editor for Special Issue in Fishes, Guest Editor
2022-01-01-今,Guest Editor for Special Issue in Genes, Guest Editor
2022-01-01-2022-12-31,Guest Editor for Special Issue in Fishes, Guest Editor
出版信息
发表论文
（1） The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation, eLife, 2024, 第 2 作者
（2） Reference genomes of channel catfish and blue catfish reveal multiple pericentric chromosome inversions, BMC Biology （共同一作）, 2023, 第 3 作者
（3） The evolutionary diversification and antimicrobial potential of MPEG1 in Metazoa, Computational and Structural Biotechnology Journal, 2023,
（4） Pyroptotic gasdermin exists in Mollusca and is vital to eliminating bacterial infection, Cell Reports, 2023, 第 4 作者
（5） Evolutionary divergence of gasdermin in regulating programmed cell death, Developmental & Comparative Immunology, 2023, 第 4 作者
（6） Characterization of the pathogenicity of a Bacillus cereus isolate from the Mariana Trench, Virulence, 2022,
（7） Allelically and Differentially Expressed Genes After Infection of Edwardsiella ictaluri in Channel Catfish as Determined by Bulk Segregant RNA-Seq, Marine Biotechnology, 2022, 第 9 作者
（8） Chromosome-level genome assembly of largemouth bass (Micropterus salmoides) using PacBio and Hi-C technologies, Scientific Data（共同一作）, 2022, 第 3 作者
（9） New insights into the evolutionary dynamic and lineage divergence of gasdermin E in metazoa, Frontiers in Cell and Developmental Biology, 2022, 第 1 作者
（10） GSDMEa-mediated pyroptosis is bi-directionally regulated by caspase and required for effective bacterial clearance in teleost, Cell Death & Disease, 2022, 第 4 作者
（11） Impairment of IgG Fc functions promotes tumor progression and suppresses NK cell antitumor actions, Communications biology, 2022, 第 2 作者
（12） Human Endogenous Retroviruses in Glioblastoma Multiforme, Microorganisms, 2021, 第 1 作者
（13） Presence of complete murine viral genome sequences in patient-derived xenografts, Nature Communications, 2021, 第 1 作者
（14） Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape, Nature Communications, 2021, 第 8 作者
（15） Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step, PLoS pathogens, 2020, 第 6 作者
（16） Virome assembly and annotation in brain tissue based on nextgeneration sequencing, Cancer Medicine, 2020, 第 1 作者
（17） Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development, Cancer Immunology Research, 2019, 第 12 作者
（18） FOXO genes in channel catfish and their response after bacterial infection, Developmental & Comparative Immunology, 2019, 第 2 作者
（19） Genome-wide comparative analysis of the SHSP, HSP60/10 and HSP90 genes reveals differential heat stress responses in estivation of the sea cucumber Apostichopus japonicus, Aquaculture Research, 2019, 第 2 作者
（20） The Y chromosome sequence of the channel catfish suggests novel sex determination mechanisms in teleost fish, BMC biology, 2019, 第 6 作者
（21） GWAS Analysis Indicated Importance of NF-��B Signaling Pathway in Host Resistance Against Motile Aeromonas Septicemia Disease in Catfish, Marine Biotechnology, 2019, 第 12 作者
（2） Reference genomes of channel catfish and blue catfish reveal multiple pericentric chromosome inversions, BMC Biology （共同一作）, 2023, 第 3 作者
（3） The evolutionary diversification and antimicrobial potential of MPEG1 in Metazoa, Computational and Structural Biotechnology Journal, 2023,
（4） Pyroptotic gasdermin exists in Mollusca and is vital to eliminating bacterial infection, Cell Reports, 2023, 第 4 作者
（5） Evolutionary divergence of gasdermin in regulating programmed cell death, Developmental & Comparative Immunology, 2023, 第 4 作者
（6） Characterization of the pathogenicity of a Bacillus cereus isolate from the Mariana Trench, Virulence, 2022,
（7） Allelically and Differentially Expressed Genes After Infection of Edwardsiella ictaluri in Channel Catfish as Determined by Bulk Segregant RNA-Seq, Marine Biotechnology, 2022, 第 9 作者
（8） Chromosome-level genome assembly of largemouth bass (Micropterus salmoides) using PacBio and Hi-C technologies, Scientific Data（共同一作）, 2022, 第 3 作者
（9） New insights into the evolutionary dynamic and lineage divergence of gasdermin E in metazoa, Frontiers in Cell and Developmental Biology, 2022, 第 1 作者
（10） GSDMEa-mediated pyroptosis is bi-directionally regulated by caspase and required for effective bacterial clearance in teleost, Cell Death & Disease, 2022, 第 4 作者
（11） Impairment of IgG Fc functions promotes tumor progression and suppresses NK cell antitumor actions, Communications biology, 2022, 第 2 作者
（12） Human Endogenous Retroviruses in Glioblastoma Multiforme, Microorganisms, 2021, 第 1 作者
（13） Presence of complete murine viral genome sequences in patient-derived xenografts, Nature Communications, 2021, 第 1 作者
（14） Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape, Nature Communications, 2021, 第 8 作者
（15） Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step, PLoS pathogens, 2020, 第 6 作者
（16） Virome assembly and annotation in brain tissue based on nextgeneration sequencing, Cancer Medicine, 2020, 第 1 作者
（17） Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development, Cancer Immunology Research, 2019, 第 12 作者
（18） FOXO genes in channel catfish and their response after bacterial infection, Developmental & Comparative Immunology, 2019, 第 2 作者
（19） Genome-wide comparative analysis of the SHSP, HSP60/10 and HSP90 genes reveals differential heat stress responses in estivation of the sea cucumber Apostichopus japonicus, Aquaculture Research, 2019, 第 2 作者
（20） The Y chromosome sequence of the channel catfish suggests novel sex determination mechanisms in teleost fish, BMC biology, 2019, 第 6 作者
（21） GWAS Analysis Indicated Importance of NF-��B Signaling Pathway in Host Resistance Against Motile Aeromonas Septicemia Disease in Catfish, Marine Biotechnology, 2019, 第 12 作者
科研活动
科研项目
（ 1 ） 全球热液病毒的组学研究与生物危害预警, 负责人, 国家任务, 2023-01--2025-12
（ 2 ） 海洋动物类群重要生命过程与演化路径, 参与, 地方任务, 2022-10--2025-09
（ 3 ） 山东省优秀青年科学基金项目（海外）, 负责人, 地方任务, 2022-04--2025-03
（ 2 ） 海洋动物类群重要生命过程与演化路径, 参与, 地方任务, 2022-10--2025-09
（ 3 ） 山东省优秀青年科学基金项目（海外）, 负责人, 地方任务, 2022-04--2025-03