083001-环境科学
083002-环境工程

自由基反应化学；高级氧化与化学发光；巯基化合物的抗氧化与促氧化行为研究

2007-09--2011-06   中国科学院生态环境研究中心   环境科学/博士

   

2021-02~现在, 中国科学院生态环境研究中心, 副研究员
2013-07~2021-02,中国科学院生态环境研究中心, 助理研究员
2011-07~2013-06,中国科学院生态环境研究中心, 生物学/博士后
2007-09~2011-06,中国科学院生态环境研究中心, 环境科学/博士

   

（1） 第十届全国环境化学大会环境自由基化学“青年报告奖”, 一等奖, 其他, 2019

（ 1 ） 检测卤代芳烃类有机物的方法, 2012, 第 2 作者, 专利号: CN102809559A

   

（1） An unprecedented free radical mechanism for the formation of DNA adducts by the carcinogenic N-sulfonated metabolite of aristolochic acids, FREE RADICAL BIOLOGY AND MEDICINE, 2023, 第 3 作者
（2） Mechanistic investigation of the differential synergistic neurotoxicity between pesticide metam sodium and copper or zinc, CHEMOSPHERE, 2023, 第 5 作者
（3） Molecular mechanism for the activation of the potent hepatotoxin acetylhydrazine: Identification of the initial N-centered radical and the secondary C-centered radical intermediates, FREE RADICAL BIOLOGY AND MEDICINE, 2023, 第11作者
（4） Mechanistic Investigation of H2O2-dependent Chemiluminescence from Tetrabromo-1,4-Benzoquinone, CHEMPHYSCHEM, 2022, 第 2 作者
（5） Molecular Mechanism for the Unprecedented Metal-Independent Hydroxyl Radical Production from Thioureas and H2O2, Environmental Science & Technology, 2022, 第 1 作者
（6） Detecting and Quantifying Polyhaloaromatic Environmental Pollutants by Chemiluminescence-Based Analytical Method, MOLECULES, 2021, 通讯作者
（7） Mechanistic Study on Chemiluminescence of Chloranilic Acid by Co(II)-Mediated Fenton-like System, JOURNAL OF ORGANIC CHEMISTRY, 2021, 第 2 作者
（8） The cell-impermeable Ru(II) polypyridyl complex as a potent intracellular photosensitizer under visible light irradiation via ion-pairing with suitable lipophilic counter-anions, FREE RADICAL BIOLOGY AND MEDICINE, 2021, 第 8 作者
（9） Structure-Activity Relationship Investigation on Reaction Mechanism between Chlorinated Quinoid Carcinogens and Clinically-Used Aldoxime Nerve-Agent Antidote under Physiological Condition, CHEMICAL RESEARCH IN TOXICOLOGY, 2021, 第 10 作者
（10） Caffeic Acid Phenyl Ester (CAPE) Protects against Iron-Mediated Cellular DNA Damage through Its Strong Iron-Binding Ability and High Lipophilicity, ANTIOXIDANTS, 2021, 通讯作者
（11） The critical role of superoxide anion radicals on delaying tetrachlorohydroquinone autooxidation by penicillamine, FREE RADICAL BIOLOGY AND MEDICINE, 2021, 第 1 作者
（12） First Direct and Unequivocal Electron Spin Resonance Spin-Trapping Evidence for pH-Dependent Production of Hydroxyl Radicals from Sulfate Radicals, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 第 3 作者
（13） An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids, FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 6 作者
（14） Chiral Os(II) Polypyridyl Complexes as Enantioselective Nuclear DNA Imaging Agents Especially Suitable for Correlative High-Resolution Light and Electron Microscopy Studies, ACS APPLIED MATERIALS & INTERFACES, 2020, 第 4 作者
（15） An unexpected antioxidant and redox activity for the classic copper-chelating drug penicillamine, FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 1 作者
（16） Unprecedented strong intrinsic chemiluminescence generation from degradation of halogenated hydroxy-quinoid pollutants by Co(II)-mediated advanced oxidation processes: The critical role of site-specific production of hydroxyl radicals, CHEMICAL ENGINEERING JOURNAL, 2020, 第 1 作者
（17） First unequivocal identification of the critical acyl radicals from the anti-tuberculosis drug isoniazid and its hydrazide analogs by complementary applications of ESR spin-trapping and HPLC/MS methods, FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 3 作者
（18） Corrigendum to "An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids" Free Radic. Biol. Med. 146 (2020) 150–159/FRBM_2019_405, FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 5 作者
（19） Molecular mechanisms and potential applications of the intrinsic chemiluminescence produced from the degradation of haloaromatic pollutants during environmentally-friendly advanced oxidation processes, ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY, 2020, 第 1 作者
（20） An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids (vol 146, pg 150, 2020), FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 5 作者
（21） Mechanism of synergistic DNA damage induced by caffeic acid phenethyl ester (CAPE) and Cu(II): Competitive binding between CAPE and DNA with Cu(II)/Cu(I), FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 2 作者
（22） Unexpected activation of N-alkyl hydroxamic acids to produce reactive N-centered free radicals and DNA damage by carcinogenic chlorinated quinones under normal physiological conditions, FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 8 作者
（23） Mechanism of unprecedented hydroxyl radical production and site-specific oxidative DNA damage by photoactivation of the classic arylhydroxamic acid carcinogens, CARCINOGENESIS, 2019, 第 5 作者
（24） Molecular mechanism for the activation of the anti-tuberculosis drug isoniazid by Mn(III): First detection and unequivocal identification of the critical N-centered isoniazidyl radical and its exact location, FREE RADICAL BIOLOGY AND MEDICINE, 2019, 第 6 作者
（25） Intrinsic chemiluminescence production from the degradation of haloaromatic pollutants during environmentally-friendly advanced oxidation processes: mechanism, structure-activity relationship and potential applications, JOURNAL OF ENVIRONMENTAL SCIENCES, 2017, 通讯作者
（26） Mechanism of intrinsic chemiluminescence production from the degradation of persistent chlorinated phenols by the fenton system: a structure-activity relationship study and the critical role of quinoid and semiquinone radical intermediates, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 第 2 作者
（27） Chemiluminescence generation from haloaromatic pollutants: structure-activity relationship, molecular mechanism and potential applications, PROGRESS IN CHEMISTRY, 2017, 通讯作者
（28） Why Does 2,3,5,6-Tetrachlorophenol Generate the Strongest Intrinsic Chemiluminescence among All Nineteen Chlorophenolic Persistent Organic Pollutants during Environmentally-friendly Advanced Oxidation Process?, SCIENTIFIC REPORTS, 2016, 第 2 作者
（29） Intrinsic Chemiluminescence Generation during Advanced Oxidation of Persistent Halogenated Aromatic Carcinogens, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2015, 第 1 作者
（30） Unprecedented hydroxyl radical-dependent two-step chemiluminescence production by polyhalogenated quinoid carcinogens and H2O2, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 第 2 作者
（31） TEMPORARY REMOVAL: An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids, FREE RADICAL BIOLOGY AND MEDICINE, 第 5 作者

   

（ 1 ） 典型巯基化合物产生活性羟基自由基的新型分子机制及生物学效应, 负责人, 国家任务, 2022-01--2025-12
（ 2 ） 钴-类Fenton体系导致卤代醌类化合物产生独特化学发光的分子机制及应用研究, 负责人, 国家任务, 2016-01--2019-12
（ 3 ） 一类新型的依赖于羟基自由基化学发光体系的研究, 负责人, 国家任务, 2013-01--2015-12