0703Z1-化学生物学

糖脂代谢相关的环境毒理学、药理学

2006-09--2012-01   北京师范大学   博士学位
2002-09--2006-06   西北农林科技大学   学士学位

   

2021-02~现在, 中国科学院生态环境研究中心, 副研究员
2015-06~2021-02,中国科学院生态环境研究中心, 助理研究员
2012-02~2015-05,军事医学科学研究院毒物药物研究所, 博士后
2006-09~2012-01,北京师范大学, 博士学位
2002-09~2006-06,西北农林科技大学, 学士学位

   

（ 1 ） 一种肝X受体的选择性激动剂及应用, 2022, 第 1 作者, 专利号: 202210782437.X

   

（1） 2,2',4,4'-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPARγ Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation, CHEMICAL RESEARCH IN TOXICOLOGY, 2022, 通讯作者
（2） Polybrominated diphenyl ether congener 99 (PBDE 99) promotes adipocyte lineage commitment of C3H10T1/2 mesenchymal stem cells, CHEMOSPHERE, 2022, 通讯作者
（3） Polychlorinated biphenyl congener 180 (PCB 180) regulates mitotic clonal expansion and enhances adipogenesis through modulation of C/EBP beta SUMOylation in preadipocytes, FOOD AND CHEMICAL TOXICOLOGY, 2021, 通讯作者
（4） Methyl tertiary-butyl ether inhibits THP-1 macrophage cholesterol efflux in vitro and accelerates atherosclerosis in ApoE-deficient mice in vivo, JOURNAL OF ENVIRONMENTAL SCIENCES, 2021, 通讯作者
（5） Exposure to HBCD promotes adipogenesis both in vitro and in vivo by interfering with Wnt6 expression, SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 第 1 作者
（6） Synthesis and biological activities of petrosiols B and D, RSC ADVANCES, 2019, 第 4 作者
（7） Effect of methyl tert-butyl ether on adipogenesis and glucose metabolism in vitro and in vivo, JOURNAL OF ENVIRONMENTAL SCIENCES, 2019, 通讯作者
（8） The brominated flame retardant PBDE 99 promotes adipogenesis via regulating mitotic clonal expansion and PPAR gamma expression, SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 通讯作者
（9） Synthesis of trisaccharide-coated magnetic nanoparticles for antibody removal, TETRAHEDRON, 2017, 第 4 作者
（10） Selective Tissue Distribution Mediates Tissue-Dependent PPAR gamma Activation and Insulin Sensitization by INT131, a Selective PPAR gamma Modulator, FRONTIERS IN PHARMACOLOGY, 2017, 第 1 作者