基本信息

季芬 女 硕导 中国科学院动物研究所
电子邮件: jifen@ioz.ac.cn
通信地址: 北京市朝阳区大屯路甲3号
邮政编码:
电子邮件: jifen@ioz.ac.cn
通信地址: 北京市朝阳区大屯路甲3号
邮政编码:
招生信息
招生专业
071006-神经生物学
071008-发育生物学
071008-发育生物学
招生方向
神经发育
教育背景
2003-09--2008-07 中国科学院北京基因组研究所 博士学位
工作经历
工作简历
2019-07~现在, 中国科学院动物研究所, 副研究员
2011-11~2019-07,中国科学院动物研究所, 助理研究员
2008-07~2011-10,中国科学院微生物研究所, 博士后
2003-09~2008-07,中国科学院北京基因组研究所, 博士学位
2011-11~2019-07,中国科学院动物研究所, 助理研究员
2008-07~2011-10,中国科学院微生物研究所, 博士后
2003-09~2008-07,中国科学院北京基因组研究所, 博士学位
专利与奖励
奖励信息
(1) 妇幼健康科学技术奖, 一等奖, 省级, 2023
(2) 麒麟科学技术奖, 其他, 2023
(3) 华夏医学科技奖, 二等奖, 省级, 2022
(2) 麒麟科学技术奖, 其他, 2023
(3) 华夏医学科技奖, 二等奖, 省级, 2022
出版信息
发表论文
(1) BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development, Developmental Cell, 2024, 第 4 作者
(2) Brain-specific Pd1 deficiency leads to cortical neurogenesis defects and depressive-like behaviors in mice, Cell Death & Differentiation, 2023,
(3) Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain, CELL PROLIFERATION, 2023, 第 11 作者
(4) Ccdc25 regulates neurogenesis during the brain development, DEVELOPMENTAL NEUROBIOLOGY, 2023, 第 11 作者
(5) Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development, CELL REPORTS, 2022, 第 6 作者
(6) Microglia homeostasis mediated by epigenetic ARID1A regulates neural progenitor cells response and leads to autism-like behaviors, MOLECULAR PSYCHIATRY, 2022, 第 3 作者
(7) Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain Development, ADVANCED SCIENCE, 2022, 第 5 作者
(8) Climate-driven flyway changes and memory-based long-distance migration, NATURE, 2021, 第 15 作者
(9) The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse, EMBO REPORTS, 2021, 第 3 作者
(10) Brain-specific Wt1 deletion leads to depressive-like behaviors in mice via the recruitment of Tet2 to modulate Epo expression, MOLECULAR PSYCHIATRY, 2020, 第 11 作者
(11) TCF20 dysfunction leads to cortical neurogenesis defects and autistic-like behaviors in mice, EMBO REPORTS, 2020, 第 3 作者
(12) Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder., NUCLEIC ACIDS RESEARCH, 2018, 第 2 作者
(13) Nap1l1 Controls Embryonic Neural Progenitor Cell Proliferation and Differentiation in the Developing Brain, CELL REPORTS, 2018, 第 11 作者
(14) UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex, STEM CELLS, 2017, 第 1 作者
(15) DISC1 Regulates Astrogenesis in the Embryonic Brain via Modulation of RAS/MEK/ERK Signaling Through RASSF7, DEVELOPMENT, 2016, 第 6 作者
(16) CHD2 Is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex, STEM CELLS, 2015, 第 2 作者
(17) Epigenetics: Major Regulators of Embryonic Neurogenesis, SCIENCE BULLETIN, 2015, 第 2 作者
(18) Ezh2 Regulates Adult Hippocampal Neurogenesis and Memory, JOURNAL OF NEUROSCIENCE, 2014, 第 2 作者
(19) Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex., EMBOREPORTS, 2014, 第 8 作者
(20) The Role of microRNAs in Neural Stem Cells and Neurogenesis, JOURNAL OF GENETICS AND GENOMICS, 2013, 第 1 作者
(21) Circulating microRNAs in hepatitis B virus-infected patients, JOURNAL OF VIRAL HEPATITIS, 2011,
(22) Dynamic changes of hbv quasispecies and deletion patterns in a chronic hepatitis b patient, JOURNAL OF MEDICAL VIROLOGY, 2009, 第 1 作者
(2) Brain-specific Pd1 deficiency leads to cortical neurogenesis defects and depressive-like behaviors in mice, Cell Death & Differentiation, 2023,
(3) Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain, CELL PROLIFERATION, 2023, 第 11 作者
(4) Ccdc25 regulates neurogenesis during the brain development, DEVELOPMENTAL NEUROBIOLOGY, 2023, 第 11 作者
(5) Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development, CELL REPORTS, 2022, 第 6 作者
(6) Microglia homeostasis mediated by epigenetic ARID1A regulates neural progenitor cells response and leads to autism-like behaviors, MOLECULAR PSYCHIATRY, 2022, 第 3 作者
(7) Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain Development, ADVANCED SCIENCE, 2022, 第 5 作者
(8) Climate-driven flyway changes and memory-based long-distance migration, NATURE, 2021, 第 15 作者
(9) The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse, EMBO REPORTS, 2021, 第 3 作者
(10) Brain-specific Wt1 deletion leads to depressive-like behaviors in mice via the recruitment of Tet2 to modulate Epo expression, MOLECULAR PSYCHIATRY, 2020, 第 11 作者
(11) TCF20 dysfunction leads to cortical neurogenesis defects and autistic-like behaviors in mice, EMBO REPORTS, 2020, 第 3 作者
(12) Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder., NUCLEIC ACIDS RESEARCH, 2018, 第 2 作者
(13) Nap1l1 Controls Embryonic Neural Progenitor Cell Proliferation and Differentiation in the Developing Brain, CELL REPORTS, 2018, 第 11 作者
(14) UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex, STEM CELLS, 2017, 第 1 作者
(15) DISC1 Regulates Astrogenesis in the Embryonic Brain via Modulation of RAS/MEK/ERK Signaling Through RASSF7, DEVELOPMENT, 2016, 第 6 作者
(16) CHD2 Is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex, STEM CELLS, 2015, 第 2 作者
(17) Epigenetics: Major Regulators of Embryonic Neurogenesis, SCIENCE BULLETIN, 2015, 第 2 作者
(18) Ezh2 Regulates Adult Hippocampal Neurogenesis and Memory, JOURNAL OF NEUROSCIENCE, 2014, 第 2 作者
(19) Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex., EMBOREPORTS, 2014, 第 8 作者
(20) The Role of microRNAs in Neural Stem Cells and Neurogenesis, JOURNAL OF GENETICS AND GENOMICS, 2013, 第 1 作者
(21) Circulating microRNAs in hepatitis B virus-infected patients, JOURNAL OF VIRAL HEPATITIS, 2011,
(22) Dynamic changes of hbv quasispecies and deletion patterns in a chronic hepatitis b patient, JOURNAL OF MEDICAL VIROLOGY, 2009, 第 1 作者
科研活动
科研项目
( 1 ) 小胶质细胞调控神经再生机制研究, 负责人, 研究所自主部署, 2024-01--2026-12
( 2 ) 神经退行性疾病免疫微环境与神经干细胞的互作机制研究, 参与, 国家任务, 2021-12--2026-01
( 3 ) 干细胞命运决定的免疫因素及调控, 参与, 国家任务, 2019-07--2023-12
( 2 ) 神经退行性疾病免疫微环境与神经干细胞的互作机制研究, 参与, 国家任务, 2021-12--2026-01
( 3 ) 干细胞命运决定的免疫因素及调控, 参与, 国家任务, 2019-07--2023-12