070303-有机化学

物理有机化学
计算有机化学
氟化学

2017-09--2020-08   加州大学洛杉矶分校   访问学者 （合作导师：Ken N. Houk）
2010-09--2013-07   南开大学   博士学位 (导师：程津培院士)

   

2021-08~现在, 中科院上海有机所, 研究员
2017-09~2020-08,加州大学洛杉矶分校, 访问学者 （合作导师：Ken N. Houk）
2013-07~2021-08,南开大学, 助理研究员，副教授
2010-09~2013-07,南开大学, 博士学位 (导师：程津培院士)

   

（1） Copper-Catalyzed Difluorocarbene Transfer Enables Modular Synthesis, Nature Chemistry, 2023, 第 4 作者  通讯作者
（2） Enzymatic ��-Ketothioester Decarbonylation Occurs in the Assembly Line of Barbamide for Skeleton Editing, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 第 4 作者
（3） 一类新基元反应的发现： 金/铑杂克莱森重排, A New Elementary Reaction: Au/Ru-Claisen Rearrangement, 有机化学, 2023, 第 2 作者
（4） Catalyst-Substrate Helical Character Matching Determines the Enantioselectivity in the Ishihara-Type Iodoarenes Catalyzed Asymmetric Kita-Dearomative Spirolactonization, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 第 6 作者  通讯作者
（5） Highly selective synthesis of all-carbon tetrasubstituted alkenes by deoxygenative alkenylation of carboxylic acids, NATURE COMMUNICATIONS, 2022, 第 5 作者  通讯作者
（6） Metal-Free C-H Functionalization via Diaryliodonium Salts with a Chemically Robust Dummy Ligand, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 第 8 作者  通讯作者
（7） Computations on Pericyclic Reactions Reveal the Richness of Ambimodal Transition States and Pericyclases, ISRAEL JOURNAL OF CHEMISTRY, 2022, 第 2 作者
（8） Enantioselective Synthesis of Planar-Chiral Macrocycles through Asymmetric Electrophilic Aromatic Amination, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 第 4 作者  通讯作者
（9） Neutral Five-Coordinate Arylated Copper(lll) Complex:Key Intermediate in Copper-Mediated Arene Trifluoromethylation, CHINESE JOURNAL OF CHEMISTRY, 2022, 第 4 作者
（10） Cleaving arene rings for acyclic alkenylnitrile synthesis, NATURE, 2021, 第 4 作者
（11） A ring expansion strategy towards diverse azaheterocycles, NATURE CHEMISTRY, 2021, 第 6 作者
（12） Highly ���-Selective Arylation and Carbonylative Arylation of 3-Bromo-3,3-difluoropropene via Nickel Catalysis, Angewandte Chemie International Edition, 2021, 第 5 作者
（13） Solvent-controlled photocatalytic divergent cyclization of alkynyl aldehydes: access to cyclopentenones and dihydropyranols, CHEMICAL SCIENCE, 2021, 第 7 作者  通讯作者
（14） High Site Selectivity in Electrophilic Aromatic Substitutions: Mechanism of C-H Thianthrenation, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 第 8 作者
（15） Cooperative Stapling of Native Peptides at Lysine and Tyrosine or Arginine with Formaldehyde, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 第 5 作者
（16） 8+2 vs 4+2 Cycloadditions of Cyclohexadienamines to Tropone and Heptafulvenes-Mechanisms and Selectivities, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 第 5 作者
（17） Ambimodal Transition States in Diels-Alder Cycloadditions of Tropolone and Tropolonate with N-Methylmaleimide**, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 第 4 作者
（18） Highly gamma-Selective Arylation and Carbonylative Arylation of 3-Bromo-3,3-difluoropropene via Nickel Catalysis, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 第 5 作者  通讯作者
（19） The Acidities of Nucleophilic Monofluoromethylation Reagents: An Anomalous alpha-Fluorine Effect, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 第 4 作者  通讯作者
（20） Mechanism and Selectivity of N-Heterocyclic Carbene-Catalyzed Desymmetrizing 4+1 and 4+2 Annulations, CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 第 2 作者  通讯作者
（21） 氮杂环卡宾催化去对称化4+1/4+2环化反应的机理与选择性, Mechanism and Selectivity of N-Heterocyclic Carbene-Catalyzed Desymmetrizing 4+1 and 4+2 Annulations, 有机化学, 2021, 第 2 作者
（22） 双齿氮配体螯合五价碘试剂介导的苯酚氧化去芳构化机理的理论研究, Mechanistic Study on the Bidentate Nitrogen-Ligated Iodine(���) Reagent Promoted Oxidative Dearomatization of Phenols, 化学学报, 2021, 第 5 作者
（23） Biomimetic Total Synthesis of (+/-)-Carbocyclinone-534 Reveals Its Biosynthetic Pathway, ORGANIC LETTERS, 2020, 第 6 作者  通讯作者
（24） Establishing Cation and Radical Donor Ability Scales of Electrophilic F, CF3, and SCF3 Transfer Reagents, ACCOUNTS OF CHEMICAL RESEARCH, 2020, 第 2 作者  通讯作者
（25） Radical-mediated C-C cleavage of unstrained cycloketones and DFT study for unusual regioselectivity, NATURE COMMUNICATIONS, 2020, 第 4 作者  通讯作者
（26） Quantification of the Activation Capabilities of Lewis/Bronsted Acid for Electrophilic Trifluoromethylthiolating Reagents, CHINESE JOURNAL OF CHEMISTRY, 2020, 第 4 作者  通讯作者
（27） Visible-Light-Driven Neutral Nitrogen Radical Mediated Intermolecular Styrene Difunctionalization, ORGANIC LETTERS, 2019, 第 3 作者  通讯作者
（28） Ambimodal Trispericyclic Transition State and Dynamic Control of Periselectivity, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 第 1 作者
（29） Mechanisms and Dynamics of Reactions Involving Entropic Intermediates, TRENDS IN CHEMISTRY, 2019, 第 3 作者
（30） Transition-Metal-Free ipso-Trifluoromethyithiolation of Lithium Aryl Boronates, ORGANIC LETTERS, 2019, 第 3 作者
（31） Metal-free directed sp(2)-C-H borylation, NATURE, 2019, 第 3 作者
（32） Near-Infrared Afterglow Luminescent Aggregation-Induced Emission Dots with Ultrahigh Tumor-to-Liver Signal Ratio for Promoted Image-Guided Cancer Surgery, NANO LETTERS, 2019, 第 5 作者
（33） Time-resolved mechanism of enzyme SpnF-catalyzed Cope rearrangement: Timing of bond formation and entropic intermediate, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 第 2 作者
（34） Controllable catalytic difluorocarbene transfer enables access to diversified fluoroalkylated arenes, NATURE CHEMISTRY, 2019, 第 2 作者
（35） Mechanism and Origins of Enantioselectivities in Spirobiindane-Based Hypervalent Iodine(III)-Induced Asymmetric Dearomatizing Spirolactonizations, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 第 4 作者  通讯作者
（36） Computational l(lll)���X BDEs for Benziodoxol(on)e-based Hypervalent Iodine Reagents: Implications for Their Functional Group Transfer Abilities, CHINESE JOURNAL OF CHEMISTRY, 2019, 第 3 作者
（37） Exploration of the Synthetic Potential of Electrophilic Trifluoromethylthiolating and Difluoromethylthiolating Reagents, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 第 4 作者  通讯作者
（38） Origin of Stereocontrol in Photoredox Organocatalysis of Asymmetric alpha-Functionalizations of Aldehydes, JOURNAL OF ORGANIC CHEMISTRY, 2018, 第 3 作者  通讯作者
（39） Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of beta-Substituted Styrenes, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 第 5 作者  通讯作者
（40） Recent Advances and Advisable Applications of Bond Energetics in Organic Chemistry, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 第 3 作者
（41） Carbon-Selective Difluoromethylation of Soft Carbon Nucleophiles with Difluoromethylated Sulfonium Ylide, Carbon-Selective Difluoromethylation of Soft Carbon Nucleophiles with Difluoromethylated Sulfonium Ylide, CHINESE JOURNAL OF CHEMISTRY, 2018, 第 3 作者  通讯作者
（42） Computational Study of the Trifluoromethyl Radical Donor Abilities of CF3 Sources, ACTA CHIMICA SINICA, 2018, 第 3 作者  通讯作者
（43） Mild Ring-Opening 1,3-Hydroborations of Non-Activated Cyclopropanes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 第 2 作者
（44） A Systematic Theoretical Study on the Acidities for Cations of Ionic Liquids in Dimethyl Sulfoxide, JOURNAL OF PHYSICAL CHEMISTRY A, 2018, 第 4 作者  通讯作者
（45） Origins of Selectivities in the Stork Diels-Alder Cycloaddition for the Synthesis of (+/-)-4-Methylenegermine, ORGANIC LETTERS, 2018, 第 1 作者
（46） 常见三氟甲基源释放三氟甲基自由基能力的理论计算研究, Computational Study of the Trifluoromethyl Radical Donor Abilities of CF3 Sources, 化学学报, 2018, 第 3 作者
（47） Origin of Stereoselectivity of the Photoinduced Asymmetric Phase Transfer-Catalyzed Perfluoroalkylation of beta-Ketoesters, JOURNAL OF ORGANIC CHEMISTRY, 2017, 第 4 作者
（48） Sulfimine-Promoted Fast O Transfer: One-step Synthesis of Sulfoximine from Sulfide, CHEMISTRYSELECT, 2017, 第 12 作者
（49） Establishing the Trifluoromethylthio Radical Donating Abilities of Electrophilic SCF3-Transfer Reagents, JOURNAL OF ORGANIC CHEMISTRY, 2017, 第 3 作者  通讯作者
（50） Design and Applications of N-tert-Butyl Sulfinyl Squaramide Catalysts, ORGANIC LETTERS, 2017, 第 5 作者
（51） Mechanism and Origins of Stereoinduction in Natural Cinchona Alkaloid Catalyzed Asymmetric Electrophilic Trifluoromethylthiolation of beta-Keto Esters with N-Trifluoromethylthiophthalimide as Electrophilic SCF3 Source, ACS CATALYSIS, 2017, 第 2 作者  通讯作者
（52） Theoretical study of Lewis acid activation models for hypervalent fluoroiodane reagent: The generality of "F-coordination" activation model, TETRAHEDRON LETTERS, 2017, 第 2 作者  通讯作者
（53） Hypervalent-Iodine-Mediated Formation of Epoxides from Carbon(sp(2))-Carbon(sp(3)) Single Bonds, JOURNAL OF ORGANIC CHEMISTRY, 2017, 第 5 作者  通讯作者
（54） An Energetic Guide for Estimating Trifluoromethyl Cation Donor Abilities of Electrophilic Trifluoromethylating Reagents: Computations of X-CF3 Bond Heterolytic Dissociation Enthalpies, JOURNAL OF ORGANIC CHEMISTRY, 2016, 第 2 作者  通讯作者
（55） N-Trifluoromethylthio-dibenzenesulfonimide: A Shelf-Stable, Broadly Applicable Electrophilic Trifluoromethylthiolating Reagent, JOURNAL OF ORGANIC CHEMISTRY, 2016, 第 3 作者  通讯作者
（56） Mechanism and Origin of the Unexpected Chemoselectivity in Fluorocyclization of o-Styryl Benzamides with a Hypervalent Fluoroiodane Reagent, JOURNAL OF ORGANIC CHEMISTRY, 2016, 第 3 作者  通讯作者
（57） Comprehensive Energetic Scale for Quantitatively Estimating the Fluorinating Potential of N-F Reagents in Electrophilic Fluorinations, JOURNAL OF ORGANIC CHEMISTRY, 2016, 第 1 作者  通讯作者
（58） A Highly Efficient Chirality Switchable Synthesis of Dihydropyran-Fused Benzofurans by Fine-Tuning the Phenolic Proton of -Isocupreidine (-ICD) Catalyst with Methyl, CHEMISTRY-A EUROPEAN JOURNAL, 2015, 第 3 作者
（59） Toward Prediction of the Chemistry in Ionic Liquids: An Accurate Computation of Absolute pK(a) Values of Benzoic Acids and Benzenethiols, JOURNAL OF ORGANIC CHEMISTRY, 2015, 第 1 作者  通讯作者
（60） Computation of standard equilibrium acidity of C-H acids in ionic media: shedding light on predicting changes of chemical behavior by switching solvent system from molecular to ionic, ORGANIC CHEMISTRY FRONTIERS, 2014, 第 1 作者  通讯作者
（61） Computational Study on the pK(a) Shifts in Proline Induced by Hydrogen-Bond-Donating Cocatalysts, JOURNAL OF ORGANIC CHEMISTRY, 2014, 第 1 作者
（62） Theoretical Study on the Acidities of Chiral Phosphoric Acids in Dimethyl Sulfoxide: Hints for Organocatalysis, JOURNAL OF ORGANIC CHEMISTRY, 2013, 第 2 作者
（63） Synthesis of Optically Enriched Spirocyclic Benzofuran-2-ones by Bifunctional Thiourea-Base Catalyzed Double-Michael Addition of Benzofuran-2-ones to Dienones, CHEMISTRY-AN ASIAN JOURNAL, 2013, 第 4 作者
（64） Mechanism and Selectivity of Bioinspired Cinchona Alkaloid Derivatives Catalyzed Asymmetric Olefin Isomerization: A Computational Study, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 第 1 作者
（65） Theoretical Study on the Thermodynamic Hydricity of Imidazole-based Organic Hydrides in Acetonitrile, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2012, 第 3 作者
（66） The effects of insertion of nitrogen atoms on the aromatic nitrogen-containing compounds: a potential approach for designing stable radical molecular materials, JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2012, 第 2 作者
（67） 咪唑类化合物在乙腈溶液中负氢解离焓的理论研究, Theoretical Study on the Thermodynamic Hydricity of Imidazole-based Organic Hydrides in Acetonitrile, 高等学校化学学报, 2012, 第 3 作者
（68） Asymmetric Michael addition reactions of 3-substituted benzofuran-2(3H)-ones to nitroolefins catalyzed by a bifunctional tertiary-amine thiourea, ORGANIC & BIOMOLECULAR CHEMISTRY, 2012, 第 2 作者
（69） Asymmetric Michael Addition Reactions between 3-Substituted Benzofuran-2(3H)-ones and 1,1-Bis(phenylsulfonyl)ethylene Catalyzed by Bifunctional Catalysts Containing Tertiary Amine and Thiourea Groups, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2012, 第 3 作者
（70） Organic radicals based on phenalenyl and verdazyl units, TETRAHEDRON LETTERS, 2011, 第 6 作者
（71） A Computational Reinvestigation of the Formation of N-Alkylpyrroles via Intermolecular Redox Amination, ORGANIC LETTERS, 2011, 第 1 作者
（72） Selective Tuning of the HOMO-LUMO Gap of Carbazole-Based Donor-Acceptor-Donor Compounds toward Different Emission Colors, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2010, 第 3 作者
（73） Theoretical Study of the Peripheral Disulfide Bridge Substituent Effects on the Antioxidant Properties of Naphthyridine Diol Derivatives, JOURNAL OF PHYSICAL CHEMISTRY A, 2010, 第 3 作者
（74） 2,5,8-Tri-tert-butyl-1,3,4,6,7,9-hexaazaphenalene: Synthesis, Crystal Structure and Calculation of Homolytic N-H Bond Dissociation Enthalpies, ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2008, 第 4 作者

   

（ 1 ） 物理有机氟化学, 负责人, 国家任务, 2022-01--2024-12
（ 2 ） 计算有机氟化学, 负责人, 中国科学院计划, 2022-01--2024-12