基本信息
郭云学  男  硕导  中国科学院南海海洋研究所
电子邮件: yunxueguo@scsio.ac.cn
通信地址: 广东广州海珠区新港西路164号2号楼302
邮政编码: 510301

研究领域

海洋环境微生物

招生信息

   
招生专业
070703-海洋生物学
招生方向
海洋生物学

教育背景

2009-09--2012-06   中山大学   博士
2006-09--2009-06   广东海洋大学   硕士
2002-09--2006-06   河北大学   本科
学历
博士研究生

学位
博士

工作经历

   
工作简历
2017-01~现在, 中国科学院南海海洋研究所, 副研究员
2015-01~2016-12,中国科学院南海海洋研究所, 助理研究员
2014-05~2014-11,美国宾夕法尼亚州立大学, 博士后
2012-07~2014-12,中国科学院南海海洋研究所, 博士后

专利与奖励

出版信息

   
发表论文
[1] Yangmei Li, Xiaoxiao Liu, Kaihao Tang, Weiquan Wang, Yunxue Guo, Xiaoxue Wang. Prophage encoding toxin/antitoxin system PfiT/PfiA inhibits Pf4 production in Pseudomonas aeruginosa. MICROBIAL BIOTECHNOLOGY[J]. 2020, 13(4): 1132-1144, https://doaj.org/article/9c70216701a24317a827c0ecc364d9a3.
[2] Fu, Xing, Guo, Yunxue, Jin, Yongguo, Ma, Meihu. Bioconversion of chitin waste using a cold-adapted chitinase to produce chitin oligosaccharides. LWT-FOOD SCIENCE AND TECHNOLOGY[J]. 2020, 133: http://dx.doi.org/10.1016/j.lwt.2020.109863.
[3] Ma, Bin, Guo, Yunxue, Fu, Xing, Jin, Yongguo. Identification and antimicrobial mechanisms of a novel peptide derived from egg white ovotransferrin hydrolysates. LWT-FOOD SCIENCE AND TECHNOLOGY[J]. 2020, 131: http://dx.doi.org/10.1016/j.lwt.2020.109720.
[4] Guo Yunxue. Identification and antimicrobial mechanisms of a novel peptide derived from egg white ovotransferrin hydrolysates. LWT-Food Science and Technology. 2020, [5] Guo, Yunxue, Li, Yangmei, Zhan, Waner, Wood, Thomas K, Wang, Xiaoxue. Resistance to oxidative stress by inner membrane protein ElaB is regulated by OxyR and RpoS. MICROBIAL BIOTECHNOLOGY[J]. 2019, 12(2): 392-404, [6] Wang, Pengxia, He, Dongmei, Li, Baiyuan, Guo, Yunxue, Wang, Weiquan, Luo, Xiongjian, Zhao, Xuanyu, Wang, Xiaoxue. Eliminating mcr-1-harbouring plasmids in clinical isolates using the CRISPR/Cas9 system. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY[J]. 2019, 74(9): 2559-2565, http://dx.doi.org/10.1093/jac/dkz246.
[7] Waner Zhan, Jianyun Yao, Kaihao Tang, Yangmei Li, Yunxue Guo, Xiaoxue Wang. Characterization of Two Toxin-Antitoxin Systems in Deep-Sea Streptomyces sp. SCSIO 02999. MARINE DRUGS[J]. 2019, 17(4): https://doaj.org/article/e4a55992adaf44a2ba78e83334ea461a.
[8] Li, Yangmei, Liu, Xiaoxiao, Tang, Kaihao, Wang, Pengxia, Zeng, Zhenshun, Guo, Yunxue, Wang, Xiaoxue. Excisionase in Pf filamentous prophage controls lysis-lysogeny decision-making in Pseudomonas aeruginosa. MOLECULAR MICROBIOLOGY[J]. 2019, 111(2): 495-513, http://dx.doi.org/10.1111/mmi.14170.
[9] Song, Sooyeon, Guo, Yunxue, Kim, JunSeob, Wang, Xiaoxue, Wood, Thomas K. Phages Mediate Bacterial Self-Recognition. CELL REPORTS[J]. 2019, 27(3): 737-+, https://doaj.org/article/f3daceef3c764365ab0dc303d6f4692b.
[10] Guo, Yunxue, Sun, Chenglong, Li, Yangmei, Tang, Kaihao, Ni, Songwei, Wang, Xiaoxue. Antitoxin HigA inhibits virulence gene mvfR expression in Pseudomonas aeruginosa. ENVIRONMENTAL MICROBIOLOGY[J]. 2019, 21(8): 2707-2723, https://www.webofscience.com/wos/woscc/full-record/WOS:000478609900007.
[11] Yao, Jianyun, Guo, Yunxue, Wang, Pengxia, Zeng, Zhenshun, Li, Baiyuan, Tang, Kaihao, Liu, Xiaoxiao, Wang, Xiaoxue. Type II toxin/antitoxin system ParE(SO)/CopA(SO) stabilizes prophage CP4So in Shewanella oneidensis. ENVIRONMENTAL MICROBIOLOGY[J]. 2018, 20(3): 1224-1239, https://www.webofscience.com/wos/woscc/full-record/WOS:000428393900023.
[12] 郭云学, 李百元, 王晓雪. 细菌的毒素-抗毒素系统:定时炸弹还是免死金牌. 微生物学报[J]. 2017, 57(11): 1708-1715, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=6094285&detailType=1.
[13] Zeng, Zhenshun, Cai, Xingsheng, Wang, Pengxia, Guo, Yunxue, Liu, Xiaoxiao, Li, Baiyuan, Wang, Xiaoxue. Biofilm Formation and Heat Stress Induce Pyomelanin Production in Deep-Sea Pseudoalteromonas sp SM9913. FRONTIERS IN MICROBIOLOGY[J]. 2017, 8: https://doaj.org/article/62028162d25f43469b83d553d63aea72.
[14] Guo, Yunxue, Liu, Xiaoxiao, Li, Baiyuan, Yao, Jianyun, Wood, Thomas K, Wang, Xiaoxue. Tail-Anchored Inner Membrane Protein ElaB Increases Resistance to Stress While Reducing Persistence in Escherichia coli. JOURNAL OF BACTERIOLOGY[J]. 2017, 199(9): http://ir.scsio.ac.cn/handle/344004/16271.
[15] Zeng, Zhenshun, Liu, Xiaoxiao, Yao, Jianyun, Guo, Yunxue, Li, Baiyuan, Li, Yangmei, Jiao, Nianzhi, Wang, Xiaoxue. Cold adaptation regulated by cryptic prophage excision in Shewanella oneidensis. ISME JOURNAL[J]. 2016, 10(12): 2787-2800, https://www.webofscience.com/wos/woscc/full-record/WOS:000394508000003.
[16] Zeng, Zhenshun, Liu, Xiaoxiao, Yao, Jianyun, Guo, Yunxue, Li, Baiyuan, Li, Yangmei, Jiao, Nianzhi, Wang, Xiaoxue. Cold adaptation regulated by cryptic prophage excision in Shewanella oneidensis. ISME JOURNAL[J]. 2016, 10(12): 2787-2800, https://www.webofscience.com/wos/woscc/full-record/WOS:000394508000003.
[17] Liu, Xiaoxiao, Li, Yangmei, Guo, Yunxue, Zeng, Zhenshun, Li, Baiyuan, Wood, Thomas K, Cai, Xingsheng, Wang, Xiaoxue. Physiological Function of Rac Prophage During Biofilm Formation and Regulation of Rac Excision in Escherichia coli K-12. SCIENTIFIC REPORTS[J]. 2015, 5: http://dx.doi.org/10.1038/srep16074.
[18] Guo, Yunxue, Quiroga, Cecilia, Chen, Qin, McAnulty, Michael J, Benedik, Michael J, Wood, Thomas K, Wang, Xiaoxue. RalR (a DNase) and RalA (a small RNA) form a type I toxin-antitoxin system in Escherichia coli. NUCLEIC ACIDS RESEARCH[J]. 2014, 42(10): 6448-6462, http://dx.doi.org/10.1093/nar/gku279.

科研活动

   
科研项目
( 1 ) IncI2型黏菌素抗性质粒上毒素-抗毒素系统的功能及调控机理研究, 负责人, 国家任务, 2020-01--2023-12
( 2 ) 冷泉系统微生物环境适应机制, 负责人, 地方任务, 2019-09--2024-08

指导学生

现指导学生

黄紫贤  硕士研究生  086000-生物与医药  

翁珏华  硕士研究生  070703-海洋生物学