085400-电子信息
071006-神经生物学
080300-光学工程

光学显微成像、神经光学
神经血管耦合、脑血流调控
生物物理建模

2015-06--2019-12   哈佛医学院/麻省总医院   博士后
2009-01--2014-08   蒙特利尔大学工学院   博士

   

2020-01~现在, 中国科学院深圳先进技术研究院, 副研究员
2015-06~2019-12,哈佛医学院/麻省总医院, 博士后
2009-01~2014-08,蒙特利尔大学工学院, 博士

   

（ 1 ） 一种线状激光窄带滤光PSD热辐射板厚测量方法, 2010, 第 4 作者, 专利号: CN200810152457.9

   

（1） Label-free assessment of hemodynamics in individual cortical brain vessels using third harmonic generation microscopy, Biomed. Opt. Express, 2020, 第 3 作者
（2） A Pilot Study Investigating Changes in Capillary Hemodynamics and Its Modulation by Exercise in the APP-PS1 Alzheimer Mouse Model, Front. Neurosci., 2019, 第 3 作者
（3） Voluntary exercise increases brain tissue oxygenation and spatially homogenizes oxygen delivery in a mouse model of Alzheimer's Disease, Neurobiol. Aging, 2019, 第 3 作者
（4） Hypertension accelerates cerebral tissue PO2 disruption in Alzheimer’s disease, Neurosci. Lett., 2019, 第 3 作者
（5） Atherosclerosis is associated with a decrease in cerebral microvascular blood flow and tissue oxygenation, PLoS One, 2019, 第 1 作者
（6） More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction, eLife, 2019, 第 1 作者
（7） Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion, J. Cereb. Blood Flow Metab., 2019, 第 1 作者
（8） Awake mouse imaging: from 2-photon microscopy to BOLD fMRI, Biol. Psychiatry Cogn. Neurosci. Neuroimaging, 2018, 第 8 作者
（9） Shear-Induced Diffusion of Red Blood Cells Measured with Dynamic Light Scattering-Optical Coherence Tomography, J. Biophotonics, 2017, 第 3 作者
（10） Development of a new bioactivatable fluorescent probe for quantification of apolipoprotein A-I proteolytic degradation in vitro and in vivo, Atherosclerosis, 2017, 第 2 作者
（11） Impact of temporal resolution on estimating capillary RBC-flux with optical coherence tomography, J. Biomed. Opt., 2017, 第 1 作者
（12） Contribution of low- and high-flux capillaries to slow hemodynamic fluctuations in the cerebral cortex of mice, J. Cereb. Blood Flow Metab., 2016, 第 1 作者
（13） Ultrasound guided fluorescence molecular tomography with improved quantification by an attenuation compensated born-normalization and in vivo preclinical study of cancer, Rev. Sci. Instrum., 2014, 第 1 作者
（14） Hybrid FMT-MRI applied to in vivo atherosclerosis imaging, Biomed. Opt. Express, 2014, 第 1 作者
（15） Low-cost three-dimensional imaging system combining fluorescence and ultrasound, J. Biomed. Opt., 2011, 第 1 作者

   

（ 1 ） 脑功能环路研究的新技术方法和工具的研发与转化, 参与, 地方任务, 2019-01--2021-12
（ 2 ） 中国科学院“****”项目, 负责人, 中国科学院计划, 2022-01--2024-12
（ 3 ） 重2021N015 高性能多光子激光扫描显微成像系统关键技术研发, 参与, 地方任务, 2021-07--2024-07

（1）Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion   2019-04-11
（2）Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion   2019-02-02
（3）Two-photon microscopy imaging of capillary red blood cell flux in mouse brain reveals vulnerability of white matter to hypoperfusion   2018-10-03
（4）Cortical depth specific capillary blood flow homogenization facilitates resting state brain oxygen delivery   2018-07-08
（5）Cerebral oxygenation and blood flow distributions along the capillary path in awake mice   2018-01-27
（6）Cerebral oxygenation and blood flow distributions along the capillary path in awake mice   2017-11-11
（7）Investigation of the red blood cells flux change during hypercapnia in the rat brain with optical coherence tomography   2015-02-07
（8）MRI-guided fiber-based fluorescence molecular tomography for preclinical atherosclerosis imaging   2014-05-28
（9）Ultrasound guided fluorescence tomography   2012-06-06
（10）A Low Cost Fluorescence/Ultrasound Multimodal imaging System   2011-09-07