基本信息
彭华 女 博导 广州国家实验室
电子邮件： hpeng@ibp.ac.cn
通信地址： 北京朝阳区大屯路15号6923房间
邮政编码：
电子邮件： hpeng@ibp.ac.cn
通信地址： 北京朝阳区大屯路15号6923房间
邮政编码：
招生信息
招生专业
100102-免疫学
招生方向
免疫学，病毒疫苗研发，肿瘤免疫治疗
出版信息
发表论文
（1） Engineered anti-PDL1 with IFN�� targets both immunoinhibitory and activating signals in the liver to break HBV immune tolerance., Gut, 2023,
（2） An engineered concealed IL-15-R elicits tumor-specific CD8+T cell responses through PD-1-cis delivery, ournal of Experimental Medicine, 2022,
（3） A tumor-specific pro-IL-12 activates preexisting cytotoxic T cells to control established tumors., Science Immunology, 2022,
（4） Non-adjuvanted interferon-armed RBD protein nasal drops protect airway infection from SARS-CoV-2, Cell Discovery, 2022,
（5） Tumor-conditional IL-15 pro-cytokine reactivates anti-tumor immunity with limited toxicity., Cell Research, 2021,
（6） Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2., Cell Research, 2021,
（7） Broad neutralization against SARS-CoV-2 variants induced by a next-generation protein vaccine V-01, Cell Discovery, 2021,
（8） Targeting tumors with IL-21 reshapes the tumor microenvironment by proliferating PD-1intTim-3-CD8+ T cells, JCI Insight, 2020,
（9） A next generation tumor-targeting IL-2 preferentially promotes tumor infiltrating CD8+ T cells response and effective tumor control, Nature Communications, 2019,
（10） PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression, Journal of Clinical Investigation, 2018,
（2） An engineered concealed IL-15-R elicits tumor-specific CD8+T cell responses through PD-1-cis delivery, ournal of Experimental Medicine, 2022,
（3） A tumor-specific pro-IL-12 activates preexisting cytotoxic T cells to control established tumors., Science Immunology, 2022,
（4） Non-adjuvanted interferon-armed RBD protein nasal drops protect airway infection from SARS-CoV-2, Cell Discovery, 2022,
（5） Tumor-conditional IL-15 pro-cytokine reactivates anti-tumor immunity with limited toxicity., Cell Research, 2021,
（6） Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2., Cell Research, 2021,
（7） Broad neutralization against SARS-CoV-2 variants induced by a next-generation protein vaccine V-01, Cell Discovery, 2021,
（8） Targeting tumors with IL-21 reshapes the tumor microenvironment by proliferating PD-1intTim-3-CD8+ T cells, JCI Insight, 2020,
（9） A next generation tumor-targeting IL-2 preferentially promotes tumor infiltrating CD8+ T cells response and effective tumor control, Nature Communications, 2019,
（10） PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression, Journal of Clinical Investigation, 2018,
科研活动
科研项目
（ 1 ） 水痘-带状疱疹病毒预防性疫苗, 负责人, 境内委托项目, 2024-06--2025-12
（ 2 ） HBV治疗性疫苗研发, 负责人, 境内委托项目, 2023-12--2024-12
（ 2 ） HBV治疗性疫苗研发, 负责人, 境内委托项目, 2023-12--2024-12