基本信息
郇聘 男 博导 中国科学院海洋研究所
电子邮件： huanpin@qdio.ac.cn
通信地址： 山东省青岛市南海路7号2号楼106
邮政编码： 266071
电子邮件： huanpin@qdio.ac.cn
通信地址： 山东省青岛市南海路7号2号楼106
邮政编码： 266071
研究领域
海洋贝类遗传与发育
招生信息
招生专业
070703-海洋生物学
090801-水产养殖
086000-生物与医药
090801-水产养殖
086000-生物与医药
招生方向
繁殖、发育与调控技术
养殖遗传学与育种生物技术
海洋生物工程
养殖遗传学与育种生物技术
海洋生物工程
教授课程
海洋生物发育遗传学
水产生物发育生物学
水产生物发育生物学
出版信息
发表论文
[1] Sun, Dehui, Huan, Pin, Liu, Baozhong. Early mesodermal development in the patellogastropod Lottia goshimai. EVOLUTIONARY APPLICATIONS[J]. 2023, 第 2 作者16(2): 250-261, http://dx.doi.org/10.1111/eva.13373.
[2] Yuxiu Xia, Pin Huan, Baozhong Liu. Shell field morphogenesis in the polyplacophoran mollusk Acanthochitona rubrolineata. EVODEVO[J]. 2023, 第 2 作者14(1): 1-16, http://dx.doi.org/10.1186/s13227-023-00209-9.
[3] Huan, Pin, Cui, Menglu, Wang, Qian, Liu, Baozhong. CRISPR/Cas9-mediated mutagenesis reveals the roles of calaxin in gastropod larval cilia. GENE[J]. 2021, 第 1 作者787: http://dx.doi.org/10.1016/j.gene.2021.145640.
[4] Tan Sujian, Huan Pin, liu baozhong. Molluscan dorsal-ventral patterning relying on BMP2/4 and Chordin provides insights into spiralian development and evolution. Molecular Biology and Evolution[J]. 2021, 第 2 作者
[5] Yang, Weihong, Huan, Pin, Liu, Baozhong. Early shell field morphogenesis of a patellogastropod mollusk predominantly relies on cell movement and F-actin dynamics. BMC DEVELOPMENTAL BIOLOGY[J]. 2020, 第 2 作者 通讯作者 20(1): http://dx.doi.org/10.1186/s12861-020-00223-3.
[6] Huan, Pin, Wang, Qian, Tan, Sujian, Liu, Baozhong. Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2020, 第 1 作者117(1): 503-512, https://www.webofscience.com/wos/woscc/full-record/WOS:000506001200073.
[7] Liu, Gang, Huan, Pin, Liu, Baozhong. Identification of three cell populations from the shell gland of a bivalve mollusc. DEVELOPMENT GENES AND EVOLUTION[J]. 2020, 第 2 作者230(1): 39-45, https://www.webofscience.com/wos/woscc/full-record/WOS:000512016500005.
[8] 杨伟红, 郇聘, 刘保忠. hedgehog基因在笠贝（Lottia goshimai）早期发育中的表达模式研究. 海洋与湖沼[J]. 2020, 第 2 作者51(4): 960-965, http://lib.cqvip.com/Qikan/Article/Detail?id=7102346668.
[9] 王倩, 郇聘, 刘保忠. 笠贝soxb、mox基因的鉴定及在足原基发育中的表达模式. 海洋与湖沼[J]. 2019, 第 2 作者50(5): 1091, http://lib.cqvip.com/Qikan/Article/Detail?id=7003027533.
[10] 谭素建, 郇聘, 刘保忠. 一种酪氨酸酶基因在笠贝初生壳形成中的表达分析. 海洋科学[J]. 2018, 第 2 作者42(9): 17-21, http://qdhys.ijournal.cn/hykx/ch/reader/view_abstract.aspx?file_no=20180903&flag=1.
[11] Yue, Xin, Huan, Pin, Hu, Yonghua, Liu, Baozhong. Integrated transcriptomic and proteomic analyses reveal potential mechanisms linking thermal stress and depressed disease resistance in the turbot Scophthalmus maximus. SCIENTIFIC REPORTS[J]. 2018, 第 2 作者8(1): https://doaj.org/article/a9ad4abdcdc74e23a730bcf75c9f8a23.
[12] Sujian Tan, Pin Huan, Baozhong Liu. An investigation of oyster TGF-β receptor genes and their potential roles in early molluscan development. GENE. 2018, 第 2 作者 通讯作者 663: 65-71, http://dx.doi.org/10.1016/j.gene.2018.04.035.
[13] Tan, Sujian, Huan, Pin, Liu, Baozhong. An investigation of oyster TGF-beta receptor genes and their potential roles in early molluscan development. GENE[J]. 2018, 第 2 作者 通讯作者 663: 65-71,
[14] Tan, Sujian, Huan, Pin, Liu, Baozhong. Expression patterns indicate that BMP2/4 and Chordin, not BMP5-8 and Gremlin, mediate dorsal-ventral patterning in the mollusk Crassostrea gigas. DEVELOPMENT GENES AND EVOLUTION[J]. 2017, 第 2 作者227(2): 75-84, http://ir.qdio.ac.cn/handle/337002/136741.
[15] Wang, Shi, Zhang, Jinbo, Jiao, Wenqian, Li, Ji, Xun, Xiaogang, Sun, Yan, Guo, Ximing, Huan, Pin, Dong, Bo, Zhang, Lingling, Hu, Xiaoli, Sun, Xiaoqing, Wang, Jing, Zhao, Chengtian, Wang, Yangfan, Wang, Dawei, Huang, Xiaoting, Wang, Ruijia, Lv, Jia, Li, Yuli, Zhang, Zhifeng, Liu, Baozhong, Lu, Wei, Hui, Yuanyuan, Liang, Jun, Zhou, Zunchun, Hou, Rui, Li, Xue, Liu, Yunchao, Li, Hengde, Ning, Xianhui, Lin, Yu, Zhao, Liang, Xing, Qiang, Dou, Jinzhuang, Li, Yangping, Mao, Junxia, Guo, Haobing, Dou, Huaiqian, Li, Tianqi, Mu, Chuang, Jiang, Wenkai, Fu, Qiang, Fu, Xiaoteng, Miao, Yan, Liu, Jian, Yu, Qian, Li, Ruojiao, Liao, Huan, Li, Xuan, Kong, Yifan, Jiang, Zhi, Chourrout, Daniel, Li, Ruiqiang, Bao, Zhenmin. Scallop genome provides insights into evolution of bilaterian karyotype and development. NATURE ECOLOGY & EVOLUTION[J]. 2017, 第 8 作者1(5): http://ir.qdio.ac.cn/handle/337002/154314.
[16] Xiaojun Zhang, Lina Sun, Jianbo Yuan, Yamin Sun, Yi Gao, Libin Zhang, Shihao Li, Hui Dai, JeanFranois Hamel, Chengzhang Liu, Yang Yu, Shilin Liu, Wenchao Lin, Kaimin Guo, Songjun Jin, Peng Xu, Kenneth B Storey, Pin Huan, Tao Zhang, Yi Zhou, Jiquan Zhang, Chenggang Lin, Xiaoni Li, Lili Xing, Da Huo, Mingzhe Sun, Lei Wang, Annie Mercier, Fuhua Li, Hongsheng Yang, Jianhai Xiang. The sea cucumber genome provides insights into morphological evolution and visceral regeneration.. PLOS BIOLOGY[J]. 2017, 第 18 作者15(10): IR_Article.
[17] Tan Sujian, Huan Pin, Liu Baozhong. Expression patterns indicate that BMP2/4 and Chordin, not BMP5-8 and Gremlin, mediate dorsal–ventral patterning in the mollusk Crassostrea gigas. DEVELOPMENT GENES AND EVOLUTION[J]. 2017, 第 2 作者
[18] Liu, Gang, Huan, Pin, Liu, Baozhong. A SoxC gene related to larval shell development and co-expression analysis of different shell formation genes in early larvae of oyster. DEVELOPMENT GENES AND EVOLUTION[J]. 2017, 第 2 作者 通讯作者 227(3): 181-188, http://ir.qdio.ac.cn/handle/337002/136878.
[19] Huang, Xiaohong, Huan, Pin, Liu, Baozhong. A comparative proteomic analysis reveals important proteins for the fertilization and early embryonic development of the oyster Crassostrea gigas. PROTEOMICS[J]. 2017, 第 2 作者17(1-2): http://ir.qdio.ac.cn/handle/337002/136405.
[20] Huan, Pin, Wang, Hongxia, Liu, Baozhong. Assessment of housekeeping genes as internal references in quantitative expression analysis during early development of oyster. GENES & GENETIC SYSTEMS[J]. 2016, 第 1 作者91(5): 257-265, http://ir.qdio.ac.cn/handle/337002/136709.
[21] Zhongxiao Li, Chao Wang, Fengjuan Jiang, Pin Huan, Baozhong Liu. Characterization and expression of a novel caspase gene: Evidence of the expansion of caspases in Crassostrea gigas. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, PART B. 2016, 第 4 作者37-45, http://dx.doi.org/10.1016/j.cbpb.2016.07.001.
[22] Li, Zhongxiao, Wang, Chao, Jiang, Fengjuan, Huan, Pin, Liu, Baozhong. Characterization and expression of a novel caspase gene: Evidence of the expansion of caspases in Crassostrea gigas. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY[J]. 2016, 第 4 作者201: 37-45, http://www.corc.org.cn/handle/1471x/2374757.
[23] Wang, Xiaofei, Liu, Baozhong, Liu, Fengsong, Huan, Pin. A calaxin Gene in the Pacific Oyster Crassostrea gigas and Its Potential Roles in Cilia. ZOOLOGICAL SCIENCE[J]. 2015, 第 4 作者 通讯作者 32(5): 419-426, https://www.webofscience.com/wos/woscc/full-record/WOS:000361955400001.
[24] Huang, Xiaohong, Liu, Baozhong, Huan, Pin. The sperm proteome of the Pacific oyster Crassostrea gigas and immunolocalization of heat shock proteins. INVERTEBRATE REPRODUCTION & DEVELOPMENT[J]. 2015, 第 3 作者 通讯作者 59(3): 111-118, https://www.webofscience.com/wos/woscc/full-record/WOS:000359740100001.
[25] Liu, Gang, Huan, Pin, Liu, Baozhong. A GATA2/3 gene potentially involved in larval shell formation of the Pacific oyster Crassostrea gigas. DEVELOPMENT GENES AND EVOLUTION[J]. 2015, 第 2 作者225(4): 253-257, https://www.webofscience.com/wos/woscc/full-record/WOS:000358876800005.
[26] 黄晓红, 郇聘, 刘保忠. 长牡蛎两种engrailed同源基因的鉴定及其与贝壳发育相关性的研究. 海洋科学[J]. 2015, 第 2 作者39(6): 15-20, http://qdhys.ijournal.cn/hykx/ch/reader/view_abstract.aspx?file_no=20150603&flag=1.
[27] Dai, Ping, Huan, Pin, Wang, Hongxia, Lu, Xia, Liu, Baozhong. Characterization of a long-chain fatty acid-CoA ligase 1 gene and association between its SNPs and growth traits in the clam Meretrix meretrix. GENE[J]. 2015, 第 2 作者566(2): 194-200, http://dx.doi.org/10.1016/j.gene.2015.04.047.
[28] Huan, Pin, Wang, Hongxia, Liu, Baozhong. A Label-Free Proteomic Analysis on Competent Larvae and Juveniles of the Pacific Oyster Crassostrea gigas. PLOS ONE[J]. 2015, 第 1 作者10(8): https://doaj.org/article/b3d373450bc7489bb6b48d5c64c28474.
[29] Sun, Lingling, Huan, Pin, Wang, Hongxia, Liu, Fengsong, Liu, Baozhong. An EGFR gene of the Pacific oyster Crassostrea gigas functions in wound healing and promotes cell proliferation. MOLECULAR BIOLOGY REPORTS[J]. 2014, 第 2 作者41(5): 2757-2765, https://www.webofscience.com/wos/woscc/full-record/WOS:000335734400007.
[30] Huan, Pin, Liu, Gang, Wang, Hongxia, Liu, Baozhong. Multiple ferritin subunit genes of the Pacific oyster Crassostrea gigas and their distinct expression patterns during early development. GENE[J]. 2014, 第 1 作者546(1): 80-88, http://dx.doi.org/10.1016/j.gene.2014.05.027.
[31] Liu Gang, Huan Pin, Liu Baozhong. Cloning and expression patterns of two Smad genes during embryonic development and shell formation of the Pacific oyster Crassostrea gigas. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2014, 第 2 作者32(6): 1224-1231, https://www.webofscience.com/wos/woscc/full-record/WOS:000344541900002.
[32] Zhao, Cui, Zhang, Xiaojun, Li, Fuhua, Huan, Pin, Xiang, Jianhai. Functional analysis of the promoter of the heat shock cognate 70 gene of the Pacific white shrimp, Litopenaeus vannamei. FISH & SHELLFISH IMMUNOLOGY[J]. 2013, 第 4 作者34(1): 397-401, http://dx.doi.org/10.1016/j.fsi.2012.09.022.
[33] Yue, Xin, Huan, Pin, Xiao, Guoqiang, Liu, Baozhong. Expression patterns of an i-type lysozyme in the clam Meretrix meretrix along with larval development. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2013, 第 2 作者41(1): 27-32, http://dx.doi.org/10.1016/j.dci.2013.04.005.
[34] Huan, Pin, Liu, Gang, Wang, Hongxia, Liu, Baozhong. Identification of a tyrosinase gene potentially involved in early larval shell biogenesis of the Pacific oyster Crassostrea gigas. DEVELOPMENT GENES AND EVOLUTION[J]. 2013, 第 1 作者223(6): 389-394, https://www.webofscience.com/wos/woscc/full-record/WOS:000325810600005.
[35] Zhao Cui, Zhang Xiaojun, Liu Chengzhang, Huan Pin, Li Fuhua, Xiang Jianhai, Huang Chao. BAC end sequencing of Pacific white shrimp Litopenaeus vannamei: a glimpse into the genome of Penaeid shrimp. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2012, 第 4 作者30(3): 456-470, http://lib.cqvip.com/Qikan/Article/Detail?id=41783563.
[36] 赵翠, 张晓军, 柳承璋, 郇聘, 李富花, 相建海, 黄超. BAC end sequencing of Pacific white shrimp Litopenaeus vannamei: a glimpse into the genome of Penaeid shrimp. 中国海洋湖沼学报：英文版[J]. 2012, 第 4 作者30(3): 456-470, http://lib.cqvip.com/Qikan/Article/Detail?id=41783563.
[37] Huan, Pin, Wang, Hongxia, Dong, Bo, Liu, Baozhong. Identification of differentially expressed proteins involved in the early larval development of the Pacific oyster Crassostrea gigas. JOURNAL OF PROTEOMICS[J]. 2012, 第 1 作者75(13): 3855-3865, http://dx.doi.org/10.1016/j.jprot.2012.04.051.
[38] Yanan You, Pin Huan, Xiaomei Wang, Baozhong Liu. The Potential Roles of a Laminin Receptor in Adhesion and Apoptosis of Cells of the Marine Bivalve Meretrix meretrix. PLOS ONE[J]. 2012, 第 2 作者7(10): https://doaj.org/article/c558ae2d98884b4892206da6a8d388f4.
[39] You, Yanan, Huan, Pin, Liu, Baozhong. RNAi assay in primary cells: a new method for gene function analysis in marine bivalve. MOLECULAR BIOLOGY REPORTS[J]. 2012, 第 2 作者39(8): 8209-8216, https://www.webofscience.com/wos/woscc/full-record/WOS:000305749200041.
[40] Huan, Pin, Wang, Hongxia, Liu, Baozhong. Transcriptomic Analysis of the Clam Meretrix meretrix on Different Larval Stages. MARINE BIOTECHNOLOGY[J]. 2012, 第 1 作者14(1): 69-78, https://www.webofscience.com/wos/woscc/full-record/WOS:000298882700007.
[41] Huan, Pin, Wang, Hongxia, Liu, Baozhong. Comparative proteomic analysis of challenged Zhikong scallop (Chlamys farreri): A new insight into the anti-Vibrio immune response of marine bivalves. FISH & SHELLFISH IMMUNOLOGY[J]. 2011, 第 1 作者31(6): 1186-1192, http://ir.qdio.ac.cn/handle/337002/11806.
[42] Xiaojun Zhang, Cui Zhao, Chao Huang, Hu Duan, Pin Huan, Chengzhang Liu, Xiuying Zhang, Yang Zhang, Fuhua Li, HongBin Zhang, Jianhai Xiang. A BAC-Based Physical Map of Zhikong Scallop (Chlamys farreri Jones et Preston). PLOS ONE[J]. 2011, 第 5 作者6(11): http://ir.qdio.ac.cn/handle/337002/11738.
[43] Chao Wang, Pin Huan, Xin Yue, Maocang Yan, Baozhong Liu. Molecular characterization of a glutathione peroxidase gene and its expression in the selected Vibrio-resistant population of the clam Meretrix meretrix. FISH AND SHELLFISH IMMUNOLOGY. 2011, 第 2 作者30(6): 1294-1302, http://ir.qdio.ac.cn/handle/337002/11900.
[44] Wang, Chao, Huan, Pin, Yue, Xin, Yan, Maocang, Liu, Baozhong. Molecular characterization of a glutathione peroxidase gene and its expression in the selected Vibrio-resistant population of the clam Meretrix meretrix. FISH & SHELLFISH IMMUNOLOGY[J]. 2011, 第 2 作者30(6): 1294-1302, http://ir.qdio.ac.cn/handle/337002/11900.
[45] 刘保忠. Mining of EST-SSR markers from clam Meretrix meretrix larvae by 454 shotgun transcriptome.. 2011,
[46] Wang, Hongxia, Huan, Pin, Lu, Xia, Liu, Baozhong. Mining of EST-SSR markers in clam Meretrix meretrix larvae from 454 shotgun transcriptome. GENES & GENETIC SYSTEMS[J]. 2011, 第 2 作者86(3): 197-205, http://ir.qdio.ac.cn/handle/337002/11898.
[47] Huan, Pin, Zhang, Xiaojun, Li, Fuhua, Zhang, Yang, Zhao, Cui, Xiang, Jianhai. Chromosomal localization and molecular marker development of the lipopolysaccharide and beta-1,3-glucan binding protein gene in the Zhikong scallop Chlamys farreri (Jones et Preston) (Pectinoida, Pectinidae). GENETICS AND MOLECULAR BIOLOGY[J]. 2010, 第 1 作者33(1): 36-43, http://ir.qdio.ac.cn/handle/337002/1610.
[48] Huan Pin, Zhang Xiaojun, Li Fuhua, Zhao Cui, Zhang Chengsong, Xiang Jianhai. Chromosomal localization of 5S rDNA in Chinese shrimp (Fenneropenaeus chinensis): a chromosome-specific marker for chromosome identification. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2010, 第 1 作者28(2): 233-238, http://lib.cqvip.com/Qikan/Article/Detail?id=36080708.
[49] HUAN Pin, ZHANG Xiaojun, LI Fuhua, ZHAO Cui, ZHANG Chengsong, XIANG Jianhai. Chromosomal localization of 5S rDNA in Chinese shrimp (Fenneropenaeus chinensis): a chromosome-specific marker for chromosome identification. 中国海洋湖沼学报：英文版[J]. 2010, 第 1 作者28(2): 233-238, http://lib.cqvip.com/Qikan/Article/Detail?id=36080708.
[50] Zhang, Xiaojun, Zhang, Yang, Scheuring, Chantel, Zhang, HongBin, Huan, Pin, Wang, Bing, Liu, Chengzhang, Li, Fuhua, Liu, Bin, Xiang, Jianhai. Construction and Characterization of a Bacterial Artificial Chromosome (BAC) Library of Pacific White Shrimp, Litopenaeus vannamei. MARINE BIOTECHNOLOGY[J]. 2010, 第 5 作者12(2): 141-149, http://www.corc.org.cn/handle/1471x/2412912.
[51] 郇聘, 张晓军, 李富花, 张洋, 赵翠, 刘保忠, 相建海. 一种栉孔扇贝丝氨酸蛋白酶基因的染色体定位及其内部SNP的研究. 遗传[J]. 2009, 第 1 作者31(12): 1241-1247, http://www.chinagene.cn/CN/10.3724/SP.J.1005.2009.01.004.
[52] 郇聘, 张晓军, 李富花, 张洋, 赵翠, 刘保忠, 相建海. 栉孔扇贝热休克蛋白70（HSP70）基因的BAC-FISH 定位. 海洋科学[J]. 2009, 第 1 作者10-15, http://qdhys.ijournal.cn/hykx/ch/reader/view_abstract.aspx?file_no=20090703&flag=1.
[53] Zhang, Yang, Zhang, Xiaojun, Scheuring, Chantel F, Zhang, HongBin, Huan, Pin, Li, Fuhua, Xiang, Jianhai. Construction and characterization of two bacterial artificial chromosome libraries of Zhikong scallop, Chlamys farreri Jones et Preston, and identification of BAC clones containing the genes involved in its innate immune system. MARINE BIOTECHNOLOGY[J]. 2008, 第 5 作者10(4): 358-365, http://ir.qdio.ac.cn/handle/337002/5727.
[2] Yuxiu Xia, Pin Huan, Baozhong Liu. Shell field morphogenesis in the polyplacophoran mollusk Acanthochitona rubrolineata. EVODEVO[J]. 2023, 第 2 作者14(1): 1-16, http://dx.doi.org/10.1186/s13227-023-00209-9.
[3] Huan, Pin, Cui, Menglu, Wang, Qian, Liu, Baozhong. CRISPR/Cas9-mediated mutagenesis reveals the roles of calaxin in gastropod larval cilia. GENE[J]. 2021, 第 1 作者787: http://dx.doi.org/10.1016/j.gene.2021.145640.
[4] Tan Sujian, Huan Pin, liu baozhong. Molluscan dorsal-ventral patterning relying on BMP2/4 and Chordin provides insights into spiralian development and evolution. Molecular Biology and Evolution[J]. 2021, 第 2 作者
[5] Yang, Weihong, Huan, Pin, Liu, Baozhong. Early shell field morphogenesis of a patellogastropod mollusk predominantly relies on cell movement and F-actin dynamics. BMC DEVELOPMENTAL BIOLOGY[J]. 2020, 第 2 作者 通讯作者 20(1): http://dx.doi.org/10.1186/s12861-020-00223-3.
[6] Huan, Pin, Wang, Qian, Tan, Sujian, Liu, Baozhong. Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2020, 第 1 作者117(1): 503-512, https://www.webofscience.com/wos/woscc/full-record/WOS:000506001200073.
[7] Liu, Gang, Huan, Pin, Liu, Baozhong. Identification of three cell populations from the shell gland of a bivalve mollusc. DEVELOPMENT GENES AND EVOLUTION[J]. 2020, 第 2 作者230(1): 39-45, https://www.webofscience.com/wos/woscc/full-record/WOS:000512016500005.
[8] 杨伟红, 郇聘, 刘保忠. hedgehog基因在笠贝（Lottia goshimai）早期发育中的表达模式研究. 海洋与湖沼[J]. 2020, 第 2 作者51(4): 960-965, http://lib.cqvip.com/Qikan/Article/Detail?id=7102346668.
[9] 王倩, 郇聘, 刘保忠. 笠贝soxb、mox基因的鉴定及在足原基发育中的表达模式. 海洋与湖沼[J]. 2019, 第 2 作者50(5): 1091, http://lib.cqvip.com/Qikan/Article/Detail?id=7003027533.
[10] 谭素建, 郇聘, 刘保忠. 一种酪氨酸酶基因在笠贝初生壳形成中的表达分析. 海洋科学[J]. 2018, 第 2 作者42(9): 17-21, http://qdhys.ijournal.cn/hykx/ch/reader/view_abstract.aspx?file_no=20180903&flag=1.
[11] Yue, Xin, Huan, Pin, Hu, Yonghua, Liu, Baozhong. Integrated transcriptomic and proteomic analyses reveal potential mechanisms linking thermal stress and depressed disease resistance in the turbot Scophthalmus maximus. SCIENTIFIC REPORTS[J]. 2018, 第 2 作者8(1): https://doaj.org/article/a9ad4abdcdc74e23a730bcf75c9f8a23.
[12] Sujian Tan, Pin Huan, Baozhong Liu. An investigation of oyster TGF-β receptor genes and their potential roles in early molluscan development. GENE. 2018, 第 2 作者 通讯作者 663: 65-71, http://dx.doi.org/10.1016/j.gene.2018.04.035.
[13] Tan, Sujian, Huan, Pin, Liu, Baozhong. An investigation of oyster TGF-beta receptor genes and their potential roles in early molluscan development. GENE[J]. 2018, 第 2 作者 通讯作者 663: 65-71,
[14] Tan, Sujian, Huan, Pin, Liu, Baozhong. Expression patterns indicate that BMP2/4 and Chordin, not BMP5-8 and Gremlin, mediate dorsal-ventral patterning in the mollusk Crassostrea gigas. DEVELOPMENT GENES AND EVOLUTION[J]. 2017, 第 2 作者227(2): 75-84, http://ir.qdio.ac.cn/handle/337002/136741.
[15] Wang, Shi, Zhang, Jinbo, Jiao, Wenqian, Li, Ji, Xun, Xiaogang, Sun, Yan, Guo, Ximing, Huan, Pin, Dong, Bo, Zhang, Lingling, Hu, Xiaoli, Sun, Xiaoqing, Wang, Jing, Zhao, Chengtian, Wang, Yangfan, Wang, Dawei, Huang, Xiaoting, Wang, Ruijia, Lv, Jia, Li, Yuli, Zhang, Zhifeng, Liu, Baozhong, Lu, Wei, Hui, Yuanyuan, Liang, Jun, Zhou, Zunchun, Hou, Rui, Li, Xue, Liu, Yunchao, Li, Hengde, Ning, Xianhui, Lin, Yu, Zhao, Liang, Xing, Qiang, Dou, Jinzhuang, Li, Yangping, Mao, Junxia, Guo, Haobing, Dou, Huaiqian, Li, Tianqi, Mu, Chuang, Jiang, Wenkai, Fu, Qiang, Fu, Xiaoteng, Miao, Yan, Liu, Jian, Yu, Qian, Li, Ruojiao, Liao, Huan, Li, Xuan, Kong, Yifan, Jiang, Zhi, Chourrout, Daniel, Li, Ruiqiang, Bao, Zhenmin. Scallop genome provides insights into evolution of bilaterian karyotype and development. NATURE ECOLOGY & EVOLUTION[J]. 2017, 第 8 作者1(5): http://ir.qdio.ac.cn/handle/337002/154314.
[16] Xiaojun Zhang, Lina Sun, Jianbo Yuan, Yamin Sun, Yi Gao, Libin Zhang, Shihao Li, Hui Dai, JeanFranois Hamel, Chengzhang Liu, Yang Yu, Shilin Liu, Wenchao Lin, Kaimin Guo, Songjun Jin, Peng Xu, Kenneth B Storey, Pin Huan, Tao Zhang, Yi Zhou, Jiquan Zhang, Chenggang Lin, Xiaoni Li, Lili Xing, Da Huo, Mingzhe Sun, Lei Wang, Annie Mercier, Fuhua Li, Hongsheng Yang, Jianhai Xiang. The sea cucumber genome provides insights into morphological evolution and visceral regeneration.. PLOS BIOLOGY[J]. 2017, 第 18 作者15(10): IR_Article.
[17] Tan Sujian, Huan Pin, Liu Baozhong. Expression patterns indicate that BMP2/4 and Chordin, not BMP5-8 and Gremlin, mediate dorsal–ventral patterning in the mollusk Crassostrea gigas. DEVELOPMENT GENES AND EVOLUTION[J]. 2017, 第 2 作者
[18] Liu, Gang, Huan, Pin, Liu, Baozhong. A SoxC gene related to larval shell development and co-expression analysis of different shell formation genes in early larvae of oyster. DEVELOPMENT GENES AND EVOLUTION[J]. 2017, 第 2 作者 通讯作者 227(3): 181-188, http://ir.qdio.ac.cn/handle/337002/136878.
[19] Huang, Xiaohong, Huan, Pin, Liu, Baozhong. A comparative proteomic analysis reveals important proteins for the fertilization and early embryonic development of the oyster Crassostrea gigas. PROTEOMICS[J]. 2017, 第 2 作者17(1-2): http://ir.qdio.ac.cn/handle/337002/136405.
[20] Huan, Pin, Wang, Hongxia, Liu, Baozhong. Assessment of housekeeping genes as internal references in quantitative expression analysis during early development of oyster. GENES & GENETIC SYSTEMS[J]. 2016, 第 1 作者91(5): 257-265, http://ir.qdio.ac.cn/handle/337002/136709.
[21] Zhongxiao Li, Chao Wang, Fengjuan Jiang, Pin Huan, Baozhong Liu. Characterization and expression of a novel caspase gene: Evidence of the expansion of caspases in Crassostrea gigas. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, PART B. 2016, 第 4 作者37-45, http://dx.doi.org/10.1016/j.cbpb.2016.07.001.
[22] Li, Zhongxiao, Wang, Chao, Jiang, Fengjuan, Huan, Pin, Liu, Baozhong. Characterization and expression of a novel caspase gene: Evidence of the expansion of caspases in Crassostrea gigas. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY[J]. 2016, 第 4 作者201: 37-45, http://www.corc.org.cn/handle/1471x/2374757.
[23] Wang, Xiaofei, Liu, Baozhong, Liu, Fengsong, Huan, Pin. A calaxin Gene in the Pacific Oyster Crassostrea gigas and Its Potential Roles in Cilia. ZOOLOGICAL SCIENCE[J]. 2015, 第 4 作者 通讯作者 32(5): 419-426, https://www.webofscience.com/wos/woscc/full-record/WOS:000361955400001.
[24] Huang, Xiaohong, Liu, Baozhong, Huan, Pin. The sperm proteome of the Pacific oyster Crassostrea gigas and immunolocalization of heat shock proteins. INVERTEBRATE REPRODUCTION & DEVELOPMENT[J]. 2015, 第 3 作者 通讯作者 59(3): 111-118, https://www.webofscience.com/wos/woscc/full-record/WOS:000359740100001.
[25] Liu, Gang, Huan, Pin, Liu, Baozhong. A GATA2/3 gene potentially involved in larval shell formation of the Pacific oyster Crassostrea gigas. DEVELOPMENT GENES AND EVOLUTION[J]. 2015, 第 2 作者225(4): 253-257, https://www.webofscience.com/wos/woscc/full-record/WOS:000358876800005.
[26] 黄晓红, 郇聘, 刘保忠. 长牡蛎两种engrailed同源基因的鉴定及其与贝壳发育相关性的研究. 海洋科学[J]. 2015, 第 2 作者39(6): 15-20, http://qdhys.ijournal.cn/hykx/ch/reader/view_abstract.aspx?file_no=20150603&flag=1.
[27] Dai, Ping, Huan, Pin, Wang, Hongxia, Lu, Xia, Liu, Baozhong. Characterization of a long-chain fatty acid-CoA ligase 1 gene and association between its SNPs and growth traits in the clam Meretrix meretrix. GENE[J]. 2015, 第 2 作者566(2): 194-200, http://dx.doi.org/10.1016/j.gene.2015.04.047.
[28] Huan, Pin, Wang, Hongxia, Liu, Baozhong. A Label-Free Proteomic Analysis on Competent Larvae and Juveniles of the Pacific Oyster Crassostrea gigas. PLOS ONE[J]. 2015, 第 1 作者10(8): https://doaj.org/article/b3d373450bc7489bb6b48d5c64c28474.
[29] Sun, Lingling, Huan, Pin, Wang, Hongxia, Liu, Fengsong, Liu, Baozhong. An EGFR gene of the Pacific oyster Crassostrea gigas functions in wound healing and promotes cell proliferation. MOLECULAR BIOLOGY REPORTS[J]. 2014, 第 2 作者41(5): 2757-2765, https://www.webofscience.com/wos/woscc/full-record/WOS:000335734400007.
[30] Huan, Pin, Liu, Gang, Wang, Hongxia, Liu, Baozhong. Multiple ferritin subunit genes of the Pacific oyster Crassostrea gigas and their distinct expression patterns during early development. GENE[J]. 2014, 第 1 作者546(1): 80-88, http://dx.doi.org/10.1016/j.gene.2014.05.027.
[31] Liu Gang, Huan Pin, Liu Baozhong. Cloning and expression patterns of two Smad genes during embryonic development and shell formation of the Pacific oyster Crassostrea gigas. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2014, 第 2 作者32(6): 1224-1231, https://www.webofscience.com/wos/woscc/full-record/WOS:000344541900002.
[32] Zhao, Cui, Zhang, Xiaojun, Li, Fuhua, Huan, Pin, Xiang, Jianhai. Functional analysis of the promoter of the heat shock cognate 70 gene of the Pacific white shrimp, Litopenaeus vannamei. FISH & SHELLFISH IMMUNOLOGY[J]. 2013, 第 4 作者34(1): 397-401, http://dx.doi.org/10.1016/j.fsi.2012.09.022.
[33] Yue, Xin, Huan, Pin, Xiao, Guoqiang, Liu, Baozhong. Expression patterns of an i-type lysozyme in the clam Meretrix meretrix along with larval development. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2013, 第 2 作者41(1): 27-32, http://dx.doi.org/10.1016/j.dci.2013.04.005.
[34] Huan, Pin, Liu, Gang, Wang, Hongxia, Liu, Baozhong. Identification of a tyrosinase gene potentially involved in early larval shell biogenesis of the Pacific oyster Crassostrea gigas. DEVELOPMENT GENES AND EVOLUTION[J]. 2013, 第 1 作者223(6): 389-394, https://www.webofscience.com/wos/woscc/full-record/WOS:000325810600005.
[35] Zhao Cui, Zhang Xiaojun, Liu Chengzhang, Huan Pin, Li Fuhua, Xiang Jianhai, Huang Chao. BAC end sequencing of Pacific white shrimp Litopenaeus vannamei: a glimpse into the genome of Penaeid shrimp. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2012, 第 4 作者30(3): 456-470, http://lib.cqvip.com/Qikan/Article/Detail?id=41783563.
[36] 赵翠, 张晓军, 柳承璋, 郇聘, 李富花, 相建海, 黄超. BAC end sequencing of Pacific white shrimp Litopenaeus vannamei: a glimpse into the genome of Penaeid shrimp. 中国海洋湖沼学报：英文版[J]. 2012, 第 4 作者30(3): 456-470, http://lib.cqvip.com/Qikan/Article/Detail?id=41783563.
[37] Huan, Pin, Wang, Hongxia, Dong, Bo, Liu, Baozhong. Identification of differentially expressed proteins involved in the early larval development of the Pacific oyster Crassostrea gigas. JOURNAL OF PROTEOMICS[J]. 2012, 第 1 作者75(13): 3855-3865, http://dx.doi.org/10.1016/j.jprot.2012.04.051.
[38] Yanan You, Pin Huan, Xiaomei Wang, Baozhong Liu. The Potential Roles of a Laminin Receptor in Adhesion and Apoptosis of Cells of the Marine Bivalve Meretrix meretrix. PLOS ONE[J]. 2012, 第 2 作者7(10): https://doaj.org/article/c558ae2d98884b4892206da6a8d388f4.
[39] You, Yanan, Huan, Pin, Liu, Baozhong. RNAi assay in primary cells: a new method for gene function analysis in marine bivalve. MOLECULAR BIOLOGY REPORTS[J]. 2012, 第 2 作者39(8): 8209-8216, https://www.webofscience.com/wos/woscc/full-record/WOS:000305749200041.
[40] Huan, Pin, Wang, Hongxia, Liu, Baozhong. Transcriptomic Analysis of the Clam Meretrix meretrix on Different Larval Stages. MARINE BIOTECHNOLOGY[J]. 2012, 第 1 作者14(1): 69-78, https://www.webofscience.com/wos/woscc/full-record/WOS:000298882700007.
[41] Huan, Pin, Wang, Hongxia, Liu, Baozhong. Comparative proteomic analysis of challenged Zhikong scallop (Chlamys farreri): A new insight into the anti-Vibrio immune response of marine bivalves. FISH & SHELLFISH IMMUNOLOGY[J]. 2011, 第 1 作者31(6): 1186-1192, http://ir.qdio.ac.cn/handle/337002/11806.
[42] Xiaojun Zhang, Cui Zhao, Chao Huang, Hu Duan, Pin Huan, Chengzhang Liu, Xiuying Zhang, Yang Zhang, Fuhua Li, HongBin Zhang, Jianhai Xiang. A BAC-Based Physical Map of Zhikong Scallop (Chlamys farreri Jones et Preston). PLOS ONE[J]. 2011, 第 5 作者6(11): http://ir.qdio.ac.cn/handle/337002/11738.
[43] Chao Wang, Pin Huan, Xin Yue, Maocang Yan, Baozhong Liu. Molecular characterization of a glutathione peroxidase gene and its expression in the selected Vibrio-resistant population of the clam Meretrix meretrix. FISH AND SHELLFISH IMMUNOLOGY. 2011, 第 2 作者30(6): 1294-1302, http://ir.qdio.ac.cn/handle/337002/11900.
[44] Wang, Chao, Huan, Pin, Yue, Xin, Yan, Maocang, Liu, Baozhong. Molecular characterization of a glutathione peroxidase gene and its expression in the selected Vibrio-resistant population of the clam Meretrix meretrix. FISH & SHELLFISH IMMUNOLOGY[J]. 2011, 第 2 作者30(6): 1294-1302, http://ir.qdio.ac.cn/handle/337002/11900.
[45] 刘保忠. Mining of EST-SSR markers from clam Meretrix meretrix larvae by 454 shotgun transcriptome.. 2011,
[46] Wang, Hongxia, Huan, Pin, Lu, Xia, Liu, Baozhong. Mining of EST-SSR markers in clam Meretrix meretrix larvae from 454 shotgun transcriptome. GENES & GENETIC SYSTEMS[J]. 2011, 第 2 作者86(3): 197-205, http://ir.qdio.ac.cn/handle/337002/11898.
[47] Huan, Pin, Zhang, Xiaojun, Li, Fuhua, Zhang, Yang, Zhao, Cui, Xiang, Jianhai. Chromosomal localization and molecular marker development of the lipopolysaccharide and beta-1,3-glucan binding protein gene in the Zhikong scallop Chlamys farreri (Jones et Preston) (Pectinoida, Pectinidae). GENETICS AND MOLECULAR BIOLOGY[J]. 2010, 第 1 作者33(1): 36-43, http://ir.qdio.ac.cn/handle/337002/1610.
[48] Huan Pin, Zhang Xiaojun, Li Fuhua, Zhao Cui, Zhang Chengsong, Xiang Jianhai. Chromosomal localization of 5S rDNA in Chinese shrimp (Fenneropenaeus chinensis): a chromosome-specific marker for chromosome identification. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2010, 第 1 作者28(2): 233-238, http://lib.cqvip.com/Qikan/Article/Detail?id=36080708.
[49] HUAN Pin, ZHANG Xiaojun, LI Fuhua, ZHAO Cui, ZHANG Chengsong, XIANG Jianhai. Chromosomal localization of 5S rDNA in Chinese shrimp (Fenneropenaeus chinensis): a chromosome-specific marker for chromosome identification. 中国海洋湖沼学报：英文版[J]. 2010, 第 1 作者28(2): 233-238, http://lib.cqvip.com/Qikan/Article/Detail?id=36080708.
[50] Zhang, Xiaojun, Zhang, Yang, Scheuring, Chantel, Zhang, HongBin, Huan, Pin, Wang, Bing, Liu, Chengzhang, Li, Fuhua, Liu, Bin, Xiang, Jianhai. Construction and Characterization of a Bacterial Artificial Chromosome (BAC) Library of Pacific White Shrimp, Litopenaeus vannamei. MARINE BIOTECHNOLOGY[J]. 2010, 第 5 作者12(2): 141-149, http://www.corc.org.cn/handle/1471x/2412912.
[51] 郇聘, 张晓军, 李富花, 张洋, 赵翠, 刘保忠, 相建海. 一种栉孔扇贝丝氨酸蛋白酶基因的染色体定位及其内部SNP的研究. 遗传[J]. 2009, 第 1 作者31(12): 1241-1247, http://www.chinagene.cn/CN/10.3724/SP.J.1005.2009.01.004.
[52] 郇聘, 张晓军, 李富花, 张洋, 赵翠, 刘保忠, 相建海. 栉孔扇贝热休克蛋白70（HSP70）基因的BAC-FISH 定位. 海洋科学[J]. 2009, 第 1 作者10-15, http://qdhys.ijournal.cn/hykx/ch/reader/view_abstract.aspx?file_no=20090703&flag=1.
[53] Zhang, Yang, Zhang, Xiaojun, Scheuring, Chantel F, Zhang, HongBin, Huan, Pin, Li, Fuhua, Xiang, Jianhai. Construction and characterization of two bacterial artificial chromosome libraries of Zhikong scallop, Chlamys farreri Jones et Preston, and identification of BAC clones containing the genes involved in its innate immune system. MARINE BIOTECHNOLOGY[J]. 2008, 第 5 作者10(4): 358-365, http://ir.qdio.ac.cn/handle/337002/5727.
科研活动
科研项目
（ 1 ） TGF-β信号通路在长牡蛎早期胚胎背部化决定及贝壳发生中的功能研究, 参与, 国家任务, 2015-01--2018-12
（ 2 ） 小G蛋白cdc42及下游效应基因维持贝壳发育区细胞边界的机制研究, 负责人, 国家任务, 2018-01--2021-12
（ 3 ） 中国科学院海洋研究所"汇泉青年学者"项目, 负责人, 研究所自主部署, 2018-01--2020-12
（ 4 ） 中国科学院青年创新促进会项目(2018年度会员), 负责人, 中国科学院计划, 2018-01--2021-12
（ 5 ） 贝类生长与品质性状的分子基础和调控机理研究（子课题）, 负责人, 国家任务, 2018-12--2022-12
（ 6 ） 山东泰山学者青年专家资助项目, 负责人, 地方任务, 2021-01--2025-12
（ 7 ） 皱纹盘鲍酪氨酸酶基因家族对贝壳性状的调控机制研究, 负责人, 国家任务, 2023-01--2026-12
（ 8 ） 特征器官的发育调控与谱系溯源, 负责人, 地方任务, 2022-10--2025-09
（ 2 ） 小G蛋白cdc42及下游效应基因维持贝壳发育区细胞边界的机制研究, 负责人, 国家任务, 2018-01--2021-12
（ 3 ） 中国科学院海洋研究所"汇泉青年学者"项目, 负责人, 研究所自主部署, 2018-01--2020-12
（ 4 ） 中国科学院青年创新促进会项目(2018年度会员), 负责人, 中国科学院计划, 2018-01--2021-12
（ 5 ） 贝类生长与品质性状的分子基础和调控机理研究（子课题）, 负责人, 国家任务, 2018-12--2022-12
（ 6 ） 山东泰山学者青年专家资助项目, 负责人, 地方任务, 2021-01--2025-12
（ 7 ） 皱纹盘鲍酪氨酸酶基因家族对贝壳性状的调控机制研究, 负责人, 国家任务, 2023-01--2026-12
（ 8 ） 特征器官的发育调控与谱系溯源, 负责人, 地方任务, 2022-10--2025-09