0805J1-纳米科学与技术

恶性肿瘤的纳米液体活检技术
肿瘤的纳米免疫治疗
腔道肿瘤解聚治疗

2009-09--2013-02   复旦大学   理学博士学位

   

2023-02~现在, 中国科学院上海硅酸盐研究所, 研究员
2018-01~2023-02,中国科学院上海硅酸盐研究所, 副研究员
2015-03~2017-12,中国科学院上海硅酸盐研究所, 助理研究员
2013-03~2015-03,同济大学, 博士后
2009-09~2013-02,复旦大学, 理学博士学位

2019-02-01-今,中国科学院青年创新促进会会员,

   

（1） 上海市优秀学术带头人, 部委级, 2023
（2） 上海市青年科技启明星, 市地级, 2019
（3） 中国科学院青年创新促进会会员, 院级, 2019
（4） 上海市青年科技英才扬帆计划, 市地级, 2016
（5） 教育部学术新人奖, , 部委级, 2011

（ 1 ） 一种肿瘤外泌体检测试剂和检测方法, 2022, 第 1 作者, 专利号: CN113884675A

（ 2 ） 一种层状双氢氧化物材料体系及其制备方法和应用, 2020, 第 2 作者, 专利号: CN112107692A

（ 3 ） 一种超小纳米水滑石-肽核酸复合材料及其制备方法和应用, 2019, 第 2 作者, 专利号: CN110522732A

（ 4 ） 一种纳米颗粒耦合探针体系在ctDNA高灵敏检测中的应用, 2018, 第 1 作者, 专利号: CN107796864A

（ 5 ） 一种高比电容磁性材料Fe2O3纳米棒包碳微电缆的制备方法, 2014, 第 1 作者, 专利号: CN103915217A

（ 6 ） 一种钼酸盐梭状纳米针晶体的制备方法, 2014, 第 2 作者, 专利号: CN103880082A

（ 7 ） 三聚氰胺对钙结石形成的热力学与动力学调控方法, 2014, 第 1 作者, 专利号: CN103884746A

（ 8 ） 二维纳米稀土硼酸盐漆酶传感器的制备方法及其应用, 2014, 第 1 作者, 专利号: CN103499625A

   

（1） Dual Tumor Exosome Biomarker Co-recognitions Based Nanoliquid Biopsy for the Accurate Early Diagnosis of Pancreatic Cancer, Acs Nano, 2023, 通讯作者
（2） RETURN TO ISSUEPREVARTICLENEXT Magnetic-Manipulated NK Cell Proliferation and Activation Enhance Immunotherapy of Orthotopic Liver Cancer, J. Am. Chem. Soc., 2023, 通讯作者
（3） Low Colorectal Tumor Removal by E-Cadherin Destruction-Enabled Tumor Cell Dissociation, NANO LETTERS, 2022, 通讯作者
（4） Non-PCR Ultrasensitive Detection of Viral RNA by a Nanoprobe-Coupling Strategy: SARS-CoV-2 as an Example, ADVANCED HEALTHCARE MATERIALS, 2022, 通讯作者
（5） Evoking tumor associated macrophages by mitochondria-targeted magnetothermal immunogenic cell death for cancer immunotherapy, BIOMATERIALS, 2022, 通讯作者
（6） Acid Neutralization and Immune Regulation by Calcium-Aluminum-Layered Double Hydroxide for Osteoporosis Reversion, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 通讯作者
（7） Dual Inhibitions on Glucose/Glutamine Metabolisms for Nontoxic Pancreatic Cancer Therapy, ACS APPLIED MATERIALS & INTERFACES, 2022, 通讯作者
（8） Nanocatalytic bacteria disintegration reverses immunosuppression of colorectal cancer, Nanocatalytic bacteria disintegration reverses immunosuppression of colorectal cancer, NATIONAL SCIENCE REVIEW, 2022, 通讯作者
（9） Mild hyperthermia-mediated osteogenesis and angiogenesis play a critical role in magnetothermal composite-induced bone regeneration, NANO TODAY, 2022, 第 2 作者
（10） A hybrid semiconducting organosilica-based O-2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy, NATURE COMMUNICATIONS, 2021, 第 13 作者
（11） Nanocatalytic Innate Immunity Activation by Mitochondrial DNA Oxidative Damage for Tumor-Specific Therapy, ADVANCED MATERIALS, 2021, 通讯作者
（12） Tumor chemical suffocation therapy by dual respiratory inhibitions, CHEMICAL SCIENCE, 2021, 通讯作者
（13） Magneto-Based Synergetic Therapy for Implant-Associated Infections via Biofilm Disruption and Innate Immunity Regulation, ADVANCED SCIENCE, 2021, 通讯作者
（14） Efficient Gene Therapy of Pancreatic Cancer via a Peptide Nucleic Acid (PNA)-Loaded Layered Double Hydroxides (LDH) Nanoplatform, SMALL, 2020, 通讯作者
（15） A materials-science perspective on tackling COVID-19, NATURE REVIEWS MATERIALS, 2020, 第 5 作者
（16） Tumor Cell Dissociation Removes Malignant Bladder Tumors, CHEM, 2020, 通讯作者
（17） Combined Magnetic Hyperthermia and Immune Therapy for Primary and Metastatic Tumor Treatments, ACS NANO, 2020, 通讯作者
（18） High-performance superparamagnetic Co-Mn-Zn ferrite nanoparticles for magnetic hyperthermia therapy of cancer, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 第 2 作者
（19） 锌锰掺杂Fe_3O_4纳米颗粒的尺寸可控合成, Synthesis of Zn, Mn doped Fe_3O_4 Nanoparticles with Tunable Size, JOURNAL OF INORGANIC MATERIALS, 2019, 通讯作者
（20） Rate- controlled nano- layered assembly mechanism of melamine- induced melamine- uric acid stones and its inhibition and elimination methods, JOURNAL OF MATERIALS CHEMISTRY B, 2019, 通讯作者
（21） Ceria nanoparticles meet hepatic ischemia-reperfusion injury: the perfect imperfection, ADVANCED MATERIALS, 2019, 通讯作者
（22） Nanocatalysts-Augmented and Photothermal-Enhanced Tumor-Specific Sequential Nanocatalytic Therapy in Both NIR-I and NIR-II Biowindows, ADVANCED MATERIALS, 2019, 第 5 作者
（23） Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy, NATURE COMMUNICATIONS, 2019, 第 13 作者
（24） 锌锰掺杂Fe3O4纳米颗粒的尺寸可控合成, Synthesis of Zn, Mn doped Fe3O4 Nanoparticles with Tunable Size, 无机材料学报, 2019, 第 5 作者
（25） Breakthrough of the final conundrum in China's milk powder adulteration incident: Formation mechanism and solutions of infant kidney stones, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 第 3 作者
（26） Ultrathin Molybdenum Carbide MXene with Fast Biodegradability for Highly Efficient Theory-Oriented Photonic Tumor Hyperthermia, ADVANCED FUNCTIONAL MATERIALS, 2019, 第 7 作者
（27） Fe-Au Nanoparticle-Coupling for Ultrasensitive Detections of Circulating Tumor DNA, ADVANCED MATERIALS, 2018, 第 1 作者
（28） Nitrogen-doped carbon nanotubes decorated poly (L-Cysteine) as a novel, ultrasensitive electrochemical sensor for simultaneous determination of theophylline and caffeine, TALANTA, 2018, 通讯作者
（29） Simultaneous Blood-Brain Barrier Crossing and Protection for Stroke Treatment Based on Edaravone-Loaded Ceria Nanoparticles, ACS NANO, 2018, 通讯作者
（30） Gas-Generating Nanoplatforms: Material Chemistry, Multifunctionality, and Gas Therapy, ADVANCED MATERIALS, 2018, 通讯作者
（31） Magnetic Targeting of Nanotheranostics Enhances Cerenkov Radiation-Induced Photodynamic Therapy, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 通讯作者
（32） Near-Infrared-Activated Upconversion Nanoprobes for Sensitive Endogenous Zn2+Detection and Selective On-Demand Photodynamic Therapy, ANALYTICAL CHEMISTRY, 2017, 第 1 作者
（33） Oxygen Vacancy Enables Markedly Enhanced Magnetic Resonance Imaging-Guided Photothermal Therapy of a Gd3+-Doped Contrast Agent, ACS NANO, 2017, 第 4 作者
（34） Near infrared-assisted Fenton reaction for tumor-specific and mitochondrial DNA-targeted photochemotherapy, BIOMATERIALS, 2017, 第 1 作者
（35） Rectangular flake-like mesoporous nico2o4 as enzyme mimic for glucose biosensing and biofuel cell, SCIENCE CHINA-MATERIALS, 2017, 通讯作者
（36） Rectangular flake-like mesoporous NiCo_2O_4 as enzyme mimic for glucose biosensing and biofuel cell, Rectangular flake-like mesoporous NiCo_2O_4 as enzyme mimic for glucose biosensing and biofuel cell, 中国科学：材料科学（英文版）, 2017, 第 5 作者

   

（ 1 ） 非晶Fe@SiO2与Au的纳米耦合体 系用于循环肿瘤DNA的特异性识别, 负责人, 国家任务, 2018-01--2020-12
（ 2 ） 分子导向磁性纳米探针用于胰腺癌外泌体的高灵敏特异性识别, 负责人, 地方任务, 2019-04--2022-03
（ 3 ） 新型低维纳米材料用于肿瘤的早期检测与安全治疗, 负责人, 中国科学院计划, 2019-02--2023-02
（ 4 ） 双纳 米粒子耦合体系用于突变BRAF基因的检测与肿瘤定位研究, 负责人, 研究所自主部署, 2018-01--2020-12
（ 5 ） ZnCoFe2O4@ZnMnFe2O4@SiO2和Au纳米编码体系的构建及肿瘤外泌体识别性能研究, 负责人, 国家任务, 2021-01--2024-12
（ 6 ） 纳米界面分子诱导信号转换技术用于新型冠状病毒核酸的高灵敏度快速检测, 负责人, 地方任务, 2020-10--2023-09
（ 7 ） 抗肿瘤无机生物医用材料, 负责人, 地方任务, 2023-05--2026-04

（1）实体肿瘤的纳米催化免疫调控   中国化学会第33届学术年会   胡萍   2023-06-16
（2）实体肿瘤的纳米免疫治疗   第二届中国纳米酶大会   2023-04-07
（3）Fe–Au Nanoparticle-Coupling for Ultrasensitive Detections of Circulating Tumor DNA   2019-03-21
（4）Ethylene Polymerization of Half-Sandwich Zirconium Complexes with Tridentate   2012-11-25
（5）Ethylene Polymerization of Titanium Complexes with Double-Duty Tridentate [ONN] Ligands   2012-11-07
（6）Ethylene (Co)Polymerization Behavior ofGroup IV Metal Complexes with an [OSSO]-Carborane Ligand   2012-06-19