基本信息
向俊锋  男  硕导  中国科学院化学研究所
电子邮件: jfxiang@iccas.ac.cn
通信地址: 北京市海淀区中关村北一街2号
邮政编码:

研究领域

   

招生信息

   
招生专业
070304-物理化学
招生方向
波谱学

教育背景

1997-09--2002-07   中国科学院理化技术研究所   博士
1992-09--1997-07   北京大学化学学院   学士
学历
   
学位
   

工作经历

   
工作简历
2016-01~现在, 中国科学院化学研究所, 分析测试中心副主任
2005-04~现在, 中国科学院化学研究所, 核磁组长
2005-04~现在, 中国科学院化学研究所, 副研究员
2002-07~2005-03,日本关西学院大学, 博士后
1997-09~2002-07,中国科学院理化技术研究所, 博士
1992-09~1997-07,北京大学化学学院, 学士
社会兼职
2012-01-01-今,北京理化分析测试技术学会波谱专业委员会, 副理事长
2012-01-01-今,北京理化分析测试技术学会, 常务理事
2012-01-01-今,中国分析测试协会, 专家组成员

教授课程

有机结构分析
核磁共振原理及应用

专利与奖励

   
奖励信息
(1) 院所两级公共技术服务中心优秀集体, 院级, 2018
(2) 北京市科学技术奖二等奖:“基于谱学技术和组学原理的中药物质基础研究的技术体系构建及应用”, 二等奖, 省级, 2015
(3) 中国分析测试协会科学技术奖二等奖:“基于纳米超分子可控组装的检测探针设计及临床应用”, 二等奖, 其他, 2014
(4) 中国药学会科学技术奖三等奖:“靶向G-四链体的药物先导物发现、研究及应用”, 三等奖, 其他, 2012
(5) “中关村物质科学大型仪器区域中心”2011年度仪器使用共享之星, 院级, 2011
(6) 中国分析测试协会科学技术奖一等奖:“基于生物靶分子识别的天然抗肿瘤分子筛选鉴定一体化技术”, 一等奖, 其他, 2009
(7) 中国分析测试协会科学技术奖三等奖:“抗肿瘤药物分子与生物大分子相互作用的谱学研究”, 三等奖, 其他, 2007
专利成果
   

出版信息

   
发表论文
(1) Ultra-tough injectable cytocompatible hydrogel for 3D cell culture and cartilage repair, Journal of Materials Chemistry B, 2018, 第 4 作者
(2) From CO2 to 4H‑Quinolizin-4-ones: A One-Pot Multicomponent Approach via Ag2O/Cs2CO3 Orthogonal Tandem Catalysis, The Journal of Organic Chemistry, 2018, 第 2 作者
(3) Ethyl-substitutive Thioflavin T as a highly-specific fluorescence probe for detecting G-quadruplex structure, Scientific Reports, 2018, 第 5 作者
(4) Ultrasensitive and high specific detection of non-small-cell lung cancer cells in human serum and clinical pleural effusion by aptamer-based fluorescence spectroscopy, Talanla, 2018, 第 3 作者
(5) MCl4n- (AuCl4-, PtCl42-, or PdCl42-) anion extraction from NanMCl4 in water using a tetraimidazolium macrocyclic receptor, Tetrahedron Letters, 2018, 第 2 作者
(6) Novel fluorescent cationic benzothiazole dye tha tresponds to G-quadruplex aptamer as a novel K+ sensor, Analyst, 2017, 第 3 作者
(7) Discrete 1 : 1 complexes and higher order assemblies formed from aminobenzene sulphonate anions and a tetraimidazolium ‘‘molecular box’’, Chem Comm, 2017, 第 4 作者
(8) Ionic liquid accelerates the crystallization of Zr-based metal–organic frameworks, Nature Comm, 2017, 第 3 作者
(9) Selective Utilization of the Methoxy Group in Lignin to Produce Acetic Acid, Angew. Chem. Int. Ed, 2017, 第 6 作者
(10) Dual effects of dimethylsulfoxide on cellulose solvating ability of 1-allyl-3-methylimidazolium chloride, Cellulose, 2016, 第 11 作者
(11) Characterizing the adsorption of poly(vinyl alcohol) on colloidal silica with aggregation-induced emission fluorophore, Langmuir, 2016, 第 4 作者
(12) Pure shift proton NMR spectroscopy and its applications, Chin. J. Magn. Reson., 2016, 第 11 作者
(13) Stabilizing G-quadruplex DNA by methylazacalix n pyridine through shape-complementary interaction, Bioorg. Med. Chem. Lett., 2016, 第 11 作者
(14) Selective recognition of specific G-quadruplex vs. duplex DNA by a phenanthroline derivative, Int. J. Biol. Macromol., 2015, 第 2 作者
(15) A comparative study for recognizing G-quadruplexes using dimeric cyanine dyes with different sizes of aromatic substituents, Anal. Methods, 2015, 第 3 作者
(16) Targeting of parallel c-myc G-quadruplex by dimeric cyanine dye supramolecular assembly: dependence on the linker length, Analyst, 2015, 第 11 作者
(17) Multicomponent self-assembled metal-organic 3 rotaxanes, J. Am. Chem. Soc., 2015, 第 11 作者
(18) Directly lighting up RNA G-quadruplexes from test tubes to living human cells, Nucleic Acids Res., 2015, 第 3 作者
(19) Controllable cy3-MTC-dye aggregates and its applications served as a chemosensor, Dyes Pigment., 2015, 第 2 作者
(20) Novel DNA catalysts based on G-quadruplex for organic synthesis, Adv. Synth. Catal., 2015, 第 2 作者
(21) Pyridostatins selectively recognize two different forms of the human telomeric G-quadruplex structures and their anti-tumor activities in vitro, Tetrahedron, 2015, 第 4 作者
(22) 2,6-Pyridodicarboxamide-bridged triptycene molecular transmission devices: converting rotation to rocking vibration, J. Org. Chem., 2015, 第 3 作者
(23) A colorimetric lead (II) ions sensor based on selective recognition of G-quadruplexes by a clip-like cyanine dye., Talanta, 2015, 第 4 作者
(24) i-Motif-modulated fluorescence detection of silver(I) with an ultrahigh specificity, Anal. Chim. Acta, 2015, 第 3 作者
(25) Cation-triggered switchable asymmetric catalysis with chiral aza-crownphos, Angew. Chem.-Int. Edit., 2015, 第 4 作者
(26) Stepwise motion in a multivalent [2](3)catenane, J. Am. Chem. Soc., 2015, 第 11 作者
(27) Non-flat bisbenzylisoquinoline alkaloid fangchinoline as a class of potent G-quadruplex stabilizer with anti-cancer activity, Chin. J. Chem., 2015, 第 2 作者
(28) Copper-catalyzed intramolecular C-C bond cleavage to construct 2-substituted quinazolinones, Eur. J. Org. Chem., 2015, 第 4 作者
(29) Cu(II)-catalyzed domino reaction of 2-halobenzamide and arylmethanamine to construct 2-aryl quinazolinone, Chin. Chem. Lett., 2015, 第 4 作者
(30) G-quadruplex induced chirality of methylazacalix 6 pyridine via unprecedented binding stoichiometry: en route to multiplex controlled molecular switch, Sci Rep, 2015, 第 3 作者
(31) Aromatic sulfonate anion-induced pseudorotaxanes: environmentally benign synthesis, selectivity, and structural characterization, Chem. Commun., 2015, 第 11 作者
(32) Tuneable dynamics of a scandium nitride cluster inside an Ih-C80 cage, Dalton Trans., 2015, 第 3 作者
(33) Dissolution mechanism of cellulose in N,N-dimethylacetamide/lithium chloride: revisiting through molecular interactions, J. Phys. Chem. B, 2015, 第 3 作者
(34) Naryl-substituted anthranilamides with intramolecular hydrogen bonds, Tetrahedron, 2014, 第 11 作者
(35) Facile synthesis of N-iodoacetyl-N'-biotinyl-3,6-dioxaoctane-1,8-diamine, Chin. J. Syn. Chem., 2014, 第 2 作者
(36) A colorimetric and fluorometric dual-modal supramolecular chemosensor and its application for HSA detection, Analyst, 2014, 第 2 作者
(37) A colorimetric temperature sensor of a cyanine dye supramolecule and its application in reversible switch, Appl. Phys. Lett., 2014, 第 2 作者
(38) A newly identified G-quadruplex as a potential target regulating Bcl-2 expression., Biochim. Biophys. Acta-Gen. Subj., 2014, 第 2 作者
(39) Construction of DNA logic gates utilizing a H+/Ag+ induced i-motif structure, Chem. Commun., 2014, 第 3 作者
(40) Tristable [n]rotaxanes: from molecular shuttle to molecular cable car, Chem. Sci., 2014, 第 2 作者
(41) Intermolecular interactions and 3D structure in cellulose-NaOH-urea aqueous system, J. Phys. Chem. B, 2014, 第 3 作者
(42) Highly sensitive chemical-vapor sensor based on thin-film organic field-effect transistors with benzothiadiazole-fused-tetrathiafulvalene, Adv. Funct. Mater., 2013, 第 4 作者
(43) Quantification of the Na+/K+ ratio based on the different response of a newly identified G-quadruplex to Na+ and K+, Chem. Commun., 2013, 第 2 作者
(44) The effect of polyhydroxylated alkaloids on maltase-glucoamylase, PLoS One, 2013, 第 2 作者
(45) G4LDB: a database for discovering and studying G-quadruplex ligands, Nucleic Acids Res., 2013, 第 2 作者
(46) Novel dual-functional regulation of a chair-like antiparallel G-quadruplex inducing assembly-disassembly of a cyanine dye, Phys. Chem. Chem. Phys., 2013, 第 3 作者
(47) Roles of flanking sequences in the binding between unimolecular parallel-stranded G-quadruplexes and ligands, Chin. Sci. Bull., 2013, 第 3 作者
(48) A novel signal-amplified strategy based on assembly reactivation for highly specific and sensitive detection of chair-like antiparallel G-quadruplex., Analyst, 2013, 第 3 作者
(49) A dual-site simultaneous binding mode in the interaction between parallel-stranded G-quadruplex d(TGGGGT)4 and cyanine dye 2,2'-diethyl-9-methyl-, Nucleic Acids Res., 2013, 第 3 作者
(50) Recognize three different human telomeric G-quadruplex conformations by quinacrine, Analyst, 2012, 第 2 作者
(51) Visual detection of potassium by a cyanine dye supramolecular aggregate responsive to G-quadruplex motif transition, Analyst, 2012, 第 2 作者
(52) Screening alpha-glucosidase inhibitors from mulberry extracts via DOSY and relaxation-edited NNR, Talanta, 2012, 第 2 作者
(53) Searching drug-like anti-cancer compound(s) based on G-quadruplex ligands, Curr. Pharm. Design, 2012, 第 2 作者
(54) NMR identification of anti-influenza lead compound targeting at PAC subunit of H5N1 polymerase, Chin. Chem. Lett., 2012, 第 3 作者
(55) Screen anti-influenza lead compounds that target the PAC subunit of H5N1 viral RNA polymerase, PLoS One, 2012, 第 3 作者
(56) Interaction between PEO-PPO-PEO copolymers and a hexapeptide in aqueous solutions, Langmuir, 2012, 第 3 作者
(57) The interaction of telomeric DNA and c-myc22 G-quadruplex with 11 natural alkaloids, Nucl. Acid Ther., 2012, 第 3 作者
(58) Complexation between triptycene-based macrotricyclic host and pi-extended viologens: formation of supramolecular poly 3 pseudorotaxanes, Chem. Commun., 2012, 第 3 作者
(59) Regulating the conformation of methylazacalix[6]pyridine by oligonucleotide BCL-2 2345 and its recognition of hydroxymethylpiperazinofullerene., J. Phys. Chem. B, 2012, 第 11 作者
(60) Mingyue Tian, Studies of the interactions between three protoberberine alkaloids and Bcl-2 by fluorescence spectroscopy, Acta Chim. Sin., 2011, 第 4 作者
(61) Constructing transferrin receptor targeted drug delivery system by using doxorubicin hydrochloride and vanadocene dichloride, Bioorg. Med. Chem. Lett., 2011, 第 2 作者
(62) Self-assembly of a new C60 compound with a L-glutamid-derived lipid unit: formation of organogels and hierarchically structured spherical particles, Soft Matter, 2011, 第 4 作者
(63) An important functional group, benzo 1,3 dioxole, of alkaloids induces the formation of the human telomeric DNA G-quadruplex, Chin. Sci. Bull., 2011, 第 11 作者
(64) alide-guided oligo(aryl-triazole-amide)s foldamers: receptors for multiple halide ions, Chem.-Eur. j., 2011, 第 2 作者
(65) Controllable assembly and cycling conversion of various supramolecular aggregates of a cyanine dye, Appl. Phys. Lett., 2011, 第 2 作者
(66) A stabilizing and denaturing dual-effect for natural polyamines interacting with G-quadruplexes depending on concentration, Biochimie, 2011, 第 2 作者
(67) , A low-bandgap conjugated polymer based on squaraine with strong two-photon absorption, Macromolecules, 2011, 第 3 作者
(68) Fishing potential antitumor agents from natural plant extracts pool by dialysis and G-quadruplex recognition, Talanta, 2011, 第 2 作者
(69) Screening anti-influenza agents that target avian influenza polymerase protein PAC from plant extracts based on NMR methods, Chem. Lett., 2011, 第 3 作者
(70) Interaction between reduced glutathione and PEO-PPO-PEO copolymers in aqueous solutions: studied by 1H NMR and spin-lattice relaxation, J. Phys. Chem. B, 2011, 第 4 作者
(71) A new tetrathiafulvalene-phenoxynaphthacenequinone dyad: switching on the intramolecular electron-transfer with UV light irradiation and metal ion coordination, Chem. Commun., 2011, 第 4 作者
(72) Effects of loops and nucleotides in G-quadruplexes on their interaction with an azacalixarene, methylazacalix[6]pyridine, J. Phys. Chem. B, 2011, 第 3 作者
(73) Synthesis and Aggregation Behavior of a Hexameric Quaternary Ammonium Surfactant, Langmuir, 2011, 第 3 作者
(74) Direct screening of G-quadruplex ligands from Kalopanax septemlobus (Thunb.) Koidz extract by high performance liquid chromatography, J. Chromatogr. A, 2011, 第 4 作者
发表著作
   

科研活动

   
科研项目
( 1 ) 金属富勒烯纳米肿瘤无创诊疗系统研制, 参与, 国家级, 2016-01--2018-12
参与会议
   

合作情况

   
项目协作单位
   

指导学生