基本信息
韩方普  男  博导  中国科学院遗传与发育生物学研究所
电子邮件: fphan@genetics.ac.cn
通信地址: 中国科学院遗传与发育生物学研究所
邮政编码: 100101

招生信息

   
招生专业
071007-遗传学
071009-细胞生物学
090102-作物遗传育种
招生方向
植物分子遗传学
植物细胞生物学

工作经历

   
工作简历
2004-03~2009-04,美国密苏里大学生物学系, 博士后
2001-01~2004-03,加拿大农业部, Visiting Fellow & Biologist
1998-08~2001-01,以色列 Weizmann 研究所, 博士后
社会兼职
2014-01-10-今,PAG Plant Chromosome Biology workshop, 召集人
2013-01-01-今,作物学报, 编委

教授课程

分子细胞遗传学
遗传学实验
遗传学实验课
遗传发育学系列讲座

专利与奖励

   
奖励信息
(1) 中科院遗传所益海嘉里优秀教师奖, 一等奖, 研究所(学校), 2014
专利成果
( 1 ) 小麦-长穗偃麦草抗赤霉病易位系的选育方法及分子标记, 2018, 第 1 作者, 专利号: 201710462612.6

( 2 ) 一种基因编辑系统及应用其对植物基因组进行编辑的方法, 2018, 第 1 作者, 专利号: 201710599030.2

( 3 ) 一种快速分析和鉴定小麦外源染色体的多色荧光原位杂交方法, 2016, 第 1 作者, 专利号: 20131027485.6

出版信息

   
发表论文
(1) Functional analysis of the glutathione S-transferases from Thinopyrum and its derivatives on wheat Fusarium head blight resistance, PLANT BIOTECHNOLOGY JOURNAL, 2023, 通讯作者
(2) New insights on the evolution of nucleolar dominance in newly resynthesized hexaploid wheat Triticum zhukovskyi, PLANT JOURNAL, 2023, 通讯作者
(3) Non–B-form DNA tends to form in centromeric regions and has undergone changes in polyploid oat subgenomes, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 第11作者
(4) Pan-centromere reveals widespread centromere repositioning of soybean genomes, Proceedings of the National Academy of Sciences of the United States of America, 2023, 第 1 作者
(5) Development and cytological characterization of wheat– Thinopyrum intermedium translocation lines with novel stripe rust resistance gene, FRONTIERS IN PLANT SCIENCE, 2023, 通讯作者
(6) Young retrotransposons and non-B DNA structures promote the establishment of dominant rye centromere in the 1RS.1BL fused centromere, The New Phytologist, 2023, 第 1 作者
(7) Systemic development of wheat-Thinopyrum elongatum translocation lines and their deployment in wheat breeding for Fusarium head blight resistance, PLANT JOURNAL, 2023, 通讯作者
(8) Autoploid origin and rapid diploidization of the tetraploid Thinopyrum elongatum revealed by genome differentiation and chromosome pairing in meiosis, PLANT JOURNAL, 2022, 通讯作者
(9) Distribution, Polymorphism and Function Characteristics of the GST-Encoding Fhb7 in Triticeae, PLANTS, 2022, 第 5 作者
(10) Prospects and challenges of epigenomics in crop improvement, GENES & GENOMICS, 2022, 通讯作者
(11) Centromeres: From chromosome biology to biotechnology applications and synthetic genomes in plants, PLANT BIOTECHNOLOGY JOURNAL, 2022, 通讯作者
(12) Establishment of a set of wheat‑rye addition lines with resistance to stem rust, TAG, 2022, 通讯作者
(13) Phosphorylation of histone H3 by Haspin regulates chromosome alignment and segregation during mitosis in maize, JOURNAL OF EXPERIMENTAL BOTANY, 2021, 通讯作者
(14) Sequence of the supernumerary B chromosome of maize provides insight into its drive mechanism and evolution, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 通讯作者
(15) Knl1 participates in spindle assembly checkpoint signaling in maize, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 第 9 作者
(16) Genome-wide mapping reveals R-loops associated with centromeric repeats in maize, GENOME RESEARCH, 2021, 通讯作者
(17) Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize, PLOS BIOLOGY, 2020, 通讯作者
(18) Rapid Birth or Death of Centromeres on Fragmented Chromosomes in Maize, PLANT CELL, 2020, 通讯作者
(19) The Cohesin Complex Subunit ZmSMC3 Participates in Meiotic Centromere Pairing in Maize., Plant Cell, 2020, 通讯作者
(20) Centromere Satellite Repeats Have Undergone Rapid Changes in Polyploid Wheat Subgenomes, PLANT CELL, 2019, 通讯作者
(21) The deposition of CENH3 in maize is stringtently regulated, Plant Journal, 2019, 通讯作者
(22) High-efficiency genome editing using a dmc1 promoter-controlled CRISPR/Cas9 system in maize, PLANT BIOTECHNOLOGY JOURNAL, 2018, 通讯作者
(23) The Behavior of the Maize B Chromosome and Centromere, GENES, 2018, 通讯作者
(24) Barbara McClintock’s Unsolved Chromosomal Mysteries: Parallels to Common Rearrangements and Karyotype Evolution, THE PLANT CELL, 2018, 第 2 作者
(25) Meiotic Studies on Combinations of Chromosomes With Different Sized Centromeres in Maize., FRONTIERS IN PLANT SCIENCE, 2018, 第 1 作者
(26) Site-specific transfer of chromosomal segments and genes in wheat engineered chromosomes, JOURNAL OF GENETICS AND GENOMICS, 2017, 第 8 作者
(27) Centromere structure and function analysis in wheat-rye translocation lines, PLANT JOURNAL, 2017, 通讯作者
(28) Cohesion and centromere activity are required for phosphorylation of histone H3 in maize, THE PLANT JOURNAL, 2017, 第 7 作者
(29) De nove centromere formation and centromeric sequence expansion in wheat and its wide hybrids., PLOS GENETICS, 2016, 通讯作者
(30) Dynamic chromatin changes associated with de novo centromere formation in maize euchromatin, PLANT JOURNAL, 2016, 通讯作者
(31) Sequential de novo centromere formation and inactivation on a chromosomal fragment in maize., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 第 7 作者
(32) Characterization of two CENH3 genes and their roles in wheat evolution, NEW PHYTOLOGIST, 2015, 通讯作者
(33) Asymmetric Epigenetic Modification and Elimination of rDNA Sequences by Polyploidization in Wheat, PLANT CELL, 2014, 通讯作者
(34) Centromere Pairing in Early Meiotic Prophase Requires Active Centromeres and Precedes Installation of the Synaptonemal Complex in Maize, PLANT CELL, 2013, 通讯作者
(35) Formation of a functional maize centromere after loss of centromeric sequences and gain of ectopic sequences, PLANT CELL, 2013, 通讯作者
(36) De novo centromere formation on a chromosome fragment in maize, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 第11作者
(37) Phosphorylation of histone H2A is associated with centromere function and maintenance in meiosis, PLANT JOURNAL, 2012, 通讯作者
(38) istinct DNA methylation patterns associated with active and inactive centromeres of the maize B chromosome., Genome Res., 2011, 第 1 作者
(39) Epigenetic aspects of centromere function in plants, CURRENT OPINION IN PLANT BIOLOGY, 2011, 第 5 作者
(40) Inactivation of a centromere during the formation of a translocation in maize, CHROMOSOME RESEARCH, 2011, 第 4 作者
(41) Centromere inactivation and reactivation reveal both genetic and epigenetic components for centromere specification, 2009, 
(42) Maize centromeres: structure, function, epigenetics., ANNUAL REVIEW OF GENETICS, 2009, 第 2 作者
(43) Minichromosome Analysis of Chromosome Pairing, Disjunction, and Sister Chromatid Cohesion in Maize W, THE PLANT CELL, 2007, 第 1 作者
(44) “远中”号小偃麦在小麦育种中的应用, 麦类作物学报, 2000, 第 9 作者
(45) 应用荧光原位杂交和染色体配对研究八倍体小冰麦中2的染色体组构成及染色体特征, 植物学报, 1999, 第 5 作者
(46) 普通小麦7B染色体的显微分离和低拷贝专化DNA序列的克隆, 科学通报, 1999, 第 6 作者
(47) 应用荧光原位杂交技术研究小冰麦异附加系TAI—27的变异, 中国科学:C辑, 1998, 第 1 作者
(48) 应用荧光原位杂交技术研究小冰麦异附加系TAI—14中的冰草染色体的变异, 植物学报:英文版, 1998, 第 1 作者
(49) 应用FISH技术鉴定一个小冰麦易位系, 植物学报:英文版, 1998, 第 1 作者
(50) 应用荧光原位杂交技术研究小冰麦异附加系TAI—27的变异, 中国科学:C辑, 1998, 第 2 作者
(51) 应用FISH技术鉴定一个小冰麦易位系, 植物学报:英文版, 1998, 第 2 作者

科研活动

   
科研项目
( 1 ) 主要农作物染色体细胞工程育种, 负责人, 国家任务, 2016-07--2020-12
( 2 ) 植物减数分裂染色体配对起始及染色体分离的分子机理, 负责人, 国家任务, 2017-01--2022-12
( 3 ) 异源多倍体小麦核型稳定的遗传机制, 负责人, 国家任务, 2020-01--2024-12
( 4 ) 植物着丝粒失活及新着丝粒形成的表观遗传学研究, 负责人, 国家任务, 2020-01--2024-12