基本信息
陈隽  女  博导  中国科学院水生生物研究所
电子邮件: chenjun@ihb.ac.cn
通信地址: 湖北武汉武昌区东湖南路7号
邮政编码:

研究领域

淡水生态毒理学

招生信息

   
招生专业
071004-水生生物学
招生方向
淡水生态学,生态毒理学

教育背景

   
学历
-- 研究生
学位
-- 博士

工作经历

2011.11--今:中国科学院水生生物研究所,研究员,2013年任博士生导师

2010.01--2010.12:英国阿伯丁大学,中国科学院访问学者,访学期间作为独立获奖人荣获英国著名信托基金会颁发的“利华休姆信托—海外访问学者奖学金”

2009.05--2009.10:英国阿伯丁大学,受“国家自然科学基金国际(地区)合作交流项目—微囊藻毒素及鱼类病原菌对鱼类免疫系统基因的影响”资助,开展合作研究

2007.07--2011.11:中国科学院水生生物研究所,副研究员,2008年任硕士生导师

2006.07--2007.07:中国科学院水生生物研究所,助理研究员

1998.07--2003.08:武汉市疾病控制中心,中级

研究方向:自水生所工作以来,主要从事蓝藻衍生污染物的生态毒理学、检测技术以及蓝藻生物控制的生理生态学机制等方面的基础研究。


社会兼职
2017-10-31-2020-10-31,武昌区人大代表,
2016-01-01-2020-12-31,中国海洋湖沼学会湖泊分会常务理事,

专利与奖励

   
奖励信息
(1) 第三届武汉青年科技奖, , 市地级, 2012
(2) 利华休姆信托—海外访问学者奖学, , 其他, 2010
(3) 中科院院长优秀奖, , 院级, 2005

出版信息

   
发表论文
(1) Excretion pattern and dynamics of glutathione detoxification of microcystins in Sprague Dawley rat., Chemosphere, 2018, 通讯作者
(2) Responses of the proteome and metabolome in livers of zebrafish exposed chronically to environmentally relevant concentrations of microcystin-LR, Environmental Science & Toxicology, 2017, 通讯作者
(3) Prolonged exposure to low-dose microcystin induces nonalcoholic steatohepatitis in mice: A systems toxicology study., Archives of toxicology, 2017, 通讯作者
(4) The role of GSH in microcystin-induced apoptosis in rat liver: involvement of oxidative stress and NF-kB, Environmental Toxicology, 2016, 通讯作者
(5) A review of reproductive toxicity of microcystins, Journal of hazardous materials, 2016, 通讯作者
(6) In situ enclosure experiments on the occurrence, development and decline of black bloom and the dynamics of its associated taste and odor compounds, Ecological Engineering, 2016, 通讯作者
(7) The role of glutathione detoxification pathway in MCLR-induced hepatotoxicity in SD rats., Environmental Toxicology, 2015, 通讯作者
(8) Effects of microcystin-LR on gut microflora in different gut regions of mice., Journal of Toxicological Sciences, 2015, 通讯作者
(9) Quantitatively evaluating detoxification of the hepatotoxic microcystin-LR through the glutathione (GSH) pathway in SD rats., Environmental Science and Pollution Research, 2015, 通讯作者
(10) 2013年洱海水华期间微囊藻毒素和浮游植物动态变化, 湖泊科学, 2015, 通讯作者
(11) Rapid Conversion and Reversible Conjugation of Glutathione Detoxification of Microcystins in Bighead Carp (Aristichthys nobilis). , Aquatic Toxicology, 2014, 通讯作者
(12) Simultaneous quantitative determination of microcystin-LR and its glutathione metabolites in rat liver by liquid chromatography-tandem mass spectrometry. , Journal of Chromatography B , 2014, 通讯作者
(13) Quantitative liquid chromatography–tandem mass spectrometry method for determination of microcystin-RR and its glutathione and cysteine conjugates in fish plasma and bile., Journal of Chromatography B , 2014, 通讯作者
(14) The role of glutathione detoxification pathway in MCLR-induced hepatotoxicity in SD rats. , Environmental Toxicology , 2014, 通讯作者
(15) A proteomic analysis of prenatal transfer of microcystin-LR induced neurotoxicity in rat offspring., Journal of Proteomics, 2014, 通讯作者
(16) Phylogenetic analysis of vertebrate CXC chemokines reveals novel lineage specific groups in teleost fish., Developmental and Comparative Immunology, 2013, 第 1 作者
(17) Off-flavor compounds from decaying cyanobacterial blooms of Lake Taihu. , J Environ Sci-China , 2013, 通讯作者
(18) Waterborne exposure to microcystin-LR alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis in zebrafish larvae., Chemosphere, 2012, 通讯作者
(19) The role of cysteine conjugation in the detoxification of microcystin-LR in liver of bighead carp (Aristichthys nobilis): a field and laboratory laboratory study., Ecotoxicology, 2012, 通讯作者
(20) Identification of cda gene in bighead carp and its expression in response to microcystin-LR., Ecotoxicol. Environ. Saf., 2012, 通讯作者
(21) Quantitatively Evaluating Detoxification of the Hepatotoxic Microcystins through the Glutathione and Cysteine Pathway in the Cyanobacteria-eating Bighead Carp., Aquatic Toxicology, 2012, 通讯作者
(22) Development of models for predicting the predominant taste and odor compounds in Taihu , PLoS ONE, 2012, 第 1 作者
(23) Metabolic Response to Oral Microcystin-LR Exposure in the Rat by NMR-based Metabonomic study, J. Proteome Res., 2012, 通讯作者
(24) Comparative Studies on the pH Dependence of DOW of Microcystin-RR and -LR using LC-MS. , TheScientificWorldJo, 2011, 通讯作者
(25) A systematic study on spatial and seasonal patterns of eight taste and odor compounds with relation to various biotic and abiotic parameters in Gonghu Bay of Lake Taihu, China. , Sci Total Environ , 2010, 第 1 作者
(26) Development and validation of a liquid chromatography–tandem mass spectrometry assay for the simultaneous quantitation of microcystin-RR and its metabolites in fish liver. , J Chromatogr A , 2010, 通讯作者
(27) Effects of temperature on the stability of microcystins in muscle of fish and its consequences for food safety. , Bull Environ Contam Toxicol, 2010, 通讯作者
(28) First identification of the hepatotoxic microcystins in the serum of a chronically exposed human population together with indication of hepatocellular damage. , Toxicol Sci , 2009, 第 1 作者
(29)  Simultaneous determination of microcystin contaminations in various vertebrates (fish, turtle, duck and water bird) from a large eutrophic Chinese lake, Lake Taihu, with toxic Microcystis blooms. , Sci Total Environ , 2009, 第 1 作者
(30) Accumulation of hepatotoxic microcystins in freshwater mussels, aquatic insect larvae and oligochaetes in a large, shallow eutrophic lake (Lake Chaohu) of subtropical China.,  Fresen Environ Bull, 2008, 第 1 作者
(31) In situ studies on the distribution patterns and dynamics of microcystins in a biomanipulation fish - bighead carp (Aristichthys nobilis). , Environ Pollut , 2007, 第 1 作者
(32) Microcystin accumulation in freshwater bivalves from Lake Taihu, China and the potential risk to human consumption. , Environ Toxicol Chem, 2007, 第 1 作者
(33) In situ studies on the bioaccumulation of microcystins in the phytoplanktivorous silver carp (Hypophthalmichthys molitrix) stocked in Lake Taihu with dense toxic Microcystis blooms.,  Aquaculture , 2006, 第 1 作者
(34) Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in a freshwater snail (Bellamya aeruginosa) from a large shallow, eutrophic lake of the subtropical China. , Environ Pollut , 2005, 第 1 作者
(35) Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in two freshwater shrimps, Palaemon modestus and Macrobrachium nipponensis, from a large shallow, eutrophic lake of the subtropical China. , Toxicon, 2005, 第 1 作者
(36) Seasonal dynamics of the hepatotoxic microcystins in various organs of four freshwater bivalves from the large eutrophic Lake Taihu of subtropical China and the risk to human consumption. , Environ Toxicol, 2005, 第 1 作者

科研活动

   
科研项目
( 1 ) 谷胱甘肽途径对微囊藻毒素-LR/RR诱导大鼠肝脏DNA损伤的抑制作用及机制探讨, 主持, 国家级, 2011-01--2013-12
( 2 ) 蓝藻水华生态灾害形成机理及防治的基础研究, 主持, 国家级, 2008-07--2012-06
( 3 ) 水生态毒理学, 主持, 国家级, 2014-01--2017-12
( 4 ) 湖泛监控指标及环境效应综合评估技术研究, 主持, 国家级, 2012-12--2016-12
( 5 ) 洱海藻类水华风险预测技术, 主持, 国家级, 2012-12--2017-12
( 6 ) 东湖典型生态系统长期变化趋势分析, 主持, 部委级, 2015-12--2016-12
( 7 ) 城市湖泊多组分在线监测平台建设, 主持, 部委级, 2016-06--2018-12
( 8 ) 三河三湖”重点流域水生动物入侵种调查编目, 主持, 国家级, 2016-01--2018-12
( 9 ) 滨湖城市湖泊生态系统退化识别与草型湖泊弹性变化阈值, 主持, 国家级, 2017-01--2020-06
( 10 ) 微囊藻毒素-LR慢性暴露对哺乳动物大鼠生殖与发育毒性的系统毒理学研究, 主持, 国家级, 2018-01--2021-12

指导学生

已指导学生

谢丽娟  硕士研究生  071004-水生生物学  

朱荣  博士研究生  071004-水生生物学  

现指导学生

刘佳睿  硕士研究生  085238-生物工程  

张佳  硕士研究生  071004-水生生物学  

张蔚珍  博士研究生  071004-水生生物学  

陈阳  硕士研究生  085238-生物工程  

陈峰  博士研究生  071004-水生生物学