基本信息
陈新文 男 博导 中国科学院武汉病毒研究所
电子邮件： chenxw@wh.iov.cn
通信地址： 湖北省武汉市武昌区小洪山中区44号
邮政编码： 430071
电子邮件： chenxw@wh.iov.cn
通信地址： 湖北省武汉市武昌区小洪山中区44号
邮政编码： 430071
研究领域
1、蜱传脑炎病毒等RNA病毒的复制机理：筛选参与病毒复制的宿主相关因子，解析其功能，阐明病毒复制机制；
2、代谢与免疫调控，关注乙酰化修饰、microRNA对代谢以及天然免疫、炎症和适应性免疫的调控机制；
3、大DNA病毒的调控细胞骨架的分子机制：识别和解析参与调控病毒诱导的细胞骨架重排的基因与机制。
招生信息
招生专业
071010-生物化学与分子生物学
071005-微生物学
100103-病原生物学
071005-微生物学
100103-病原生物学
招生方向
乙型肝炎病毒（HBV）和丙型肝炎病毒(HCV)的分子生物学
杆状病毒载体系统并用于重要疾病的基因治疗
杆状病毒载体系统并用于重要疾病的基因治疗
教育背景
学历
荷兰农业大学 19980901--20010801 研究生毕业
学位
荷兰农业大学 19980901--20010801 理学博士学位
工作经历
工作简历
2008-09--今 中国科学院武汉病毒研究所 所长
2002-06--今 中国科学院武汉病毒研究所 博士生导师
2000-04--今 中国科学院武汉病毒研究所 研究员
2002-06--今 中国科学院武汉病毒研究所 博士生导师
2000-04--今 中国科学院武汉病毒研究所 研究员
社会兼职
2011-05--2014-05 省（自治区、直辖市）科协委员
2011-01--2014-01 全国科协委员
2011-01--2014-01 全国科协委员
专利与奖励
一种丙型肝炎病毒自然感染小鼠模型。唐宏，陈新文，陈继征，赵洋，张超，陈海荣。专利号：ZL 2013 10502450.6 授权日：2015年3月18日
奖励信息
（1） 国家技术发明，二等奖，国家级，2005
（2） 湖北省科学技术发明，三等奖，省级，2004
（2） 湖北省科学技术发明，三等奖，省级，2004
出版信息
发表论文
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JOURNAL OF MEDICAL VIROLOGY[J]. 2023, 95(1): [3] Chen, Yingshan, Yao, Yongxuan, Zhao, Kaitao, Liu, Canyu, Yuan, Yifei, Sun, Hao, Huang, Dan, Zheng, Yi, Zhou, Yuan, Chen, Jizheng, Wang, Yun, Wu, Chunchen, Zhang, Bixiang, Guan, Yujuan, Li, Feng, Pei, Rongjuan, Chen, Xinwen. DNA Repair Factor Poly(ADP-Ribose) Polymerase 1 Is a Proviral Factor in Hepatitis B Virus Covalently Closed Circular DNA Formation. JOURNAL OF VIROLOGY[J]. 2022, 96(13): http://dx.doi.org/10.1128/jvi.00585-22.[4] ShanShan Gao, Run Shi, Jing Sun, Yanhong Tang, Zhenhua Zheng, JingFeng Li, Huan Li, Jie Zhang, Qibin Leng, Jiang Xu, Xinwen Chen, Jincun Zhao, ManSun Sy, Liqiang Feng, Chaoyang Li. GPI-anchored ligand-BioID2-tagging system identifies Galectin-1 mediating Zika virus entry. ISCIENCE. 2022, 25(12): http://dx.doi.org/10.1016/j.isci.2022.105481.[5] Yang, Qi, Pei, Rongjuan, Wang, Yun, Zhou, Yuan, Yang, Min, Chen, Xinwen, Chen, Jizheng. ADAM15 Participates in Tick-Borne Encephalitis Virus Replication. JOURNAL OF VIROLOGY[J]. 2021, 95(4): https://www.webofscience.com/wos/woscc/full-record/WOS:000615928800011.[6] Mengyuan Ren, Rongjuan Pei, Bahabaike Jiangtulu, Junxi Chen, Tao Xue, Guofeng Shen, Xiaoru Yuan, Kexin Li, Changxin Lan, Zhen Chen, Xinwen Chen, Yun Wang, Xiaoqian Jia, Zewu Li, Audil Rashid, Tippawan Prapamontol, Xiuge Zhao, Zhaomin Dong, Yali Zhang, Le Zhang, Rongwei Ye, Zhiwen Li, Wuxiang Guan, Bin Wang. Contribution of Temperature Increase to Restrain the Transmission of COVID-19. 创新(英文)[J]. 2021, 2(1): 100071-, http://lib.cqvip.com/Qikan/Article/Detail?id=7104965045.[7] Liu, FengLiang, Wu, Kaixin, Sun, Jiaoyang, Duan, Zilei, Quan, Xiongzhi, Kuang, Junqi, Chu, Shilong, Pang, Wei, Gao, Han, Xu, Ling, Li, YingChang, Zhang, HaiLin, Wang, XueHui, Luo, RongHua, Feng, XiaoLi, Schoeler, Hans R, Chen, Xinwen, Pei, Duanqing, Wu, Guangming, Zheng, YongTang, Chen, Jiekai. Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation. NATIONAL SCIENCE REVIEW[J]. 2021, 8(2): 9-11, http://lib.cqvip.com/Qikan/Article/Detail?id=7104077532.[8] Li, Jing, Hu, Yangyang, Yuan, Yifei, Zhao, Yinan, Han, Qiqi, Liu, Canyu, Hu, Xue, Zhou, Yuan, Wang, Yun, Guo, Yu, Wu, Chunchen, Chen, Xinwen, Pei, Rongjuan. Repurposing of Antazoline Hydrochloride as an Inhibitor of Hepatitis B Virus DNA Secretion. VIROLOGICA SINICA[J]. 2021, 36(3): 501-509, http://dx.doi.org/10.1007/s12250-020-00306-2.[9] Xu, Ling, Yu, Dandan, Peng, Li, Wu, Yong, Fan, Yu, Gu, Tianle, Yao, YuLin, Zhong, Jin, Chen, Xinwen, Yao, YongGang. An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3. JOURNAL OF IMMUNOLOGY[J]. 2020, 204(12): 3191-3204, https://www.webofscience.com/wos/woscc/full-record/WOS:000540261500014.[10] Yang, Qi, Tang, Jielin, Xu, Chonghui, Zhao, He, Zhou, Yuan, Wang, Yanyi, Yang, Min, Chen, Xinwen, Chen, Jizheng. Histone deacetylase 4 inhibits NF-kappa B activation by facilitating I kappa B alpha sumoylation. JOURNAL OF MOLECULAR CELL BIOLOGY[J]. 2020, 12(12): 933-945, https://www.webofscience.com/wos/woscc/full-record/WOS:000634891000004.[11] Lin, Yong, Wu, Chunchen, Wang, Xueyu, Liu, Shi, Zhao, Kaitao, Kemper, Thekla, Yu, Haisheng, Li, Mengqi, Zhang, Jiming, Chen, Mingzhou, Zhu, Ying, Chen, Xinwen, Lu, Mengji. Glucosamine promotes hepatitis B virus replication through its dual effects in suppressing autophagic degradation and inhibiting MTORC1 signaling. AUTOPHAGY[J]. 2020, 16(3): 548-561, https://www.webofscience.com/wos/woscc/full-record/WOS:000473099200001.[12] Wong, Gary, Bi, YuHai, Wang, QiHui, Chen, XinWen, Zhang, ZhiGang, Yao, YongGang. Zoonotic origins of human coronavirus 2019 (HCoV-19/SARS-CoV-2): why is this work important?. ZOOLOGICAL RESEARCH[J]. 2020, 41(3): 213-219, http://lib.cqvip.com/Qikan/Article/Detail?id=7101879881.[13] Jizheng Chen, Zhilei Zhang, Ning Wang, Min Guo, Xiumei Chi, Yu Pan, Jing Jiang, Junqi Niu, Sulaiman Ksimu, John Zhong Li, Xinwen Chen, Qian Wang. Author Correction: Role of HDAC9-FoxO1 Axis in the Transcriptional Program Associated with Hepatic Gluconeogenesis. SCIENTIFIC REPORTS[J]. 2020, 10(1): 1-2, http://dx.doi.org/10.1038/s41598-020-66085-8.[14] Wong Gary, Bi YuHai, Wang QiHui, Chen XinWen, Zhang ZhiGang, Yao YongGang. oonotic origins of human coronavirus 2019 (HCoV-19 / SARS-CoV-2): why is this work important?. ZOOLOGICAL RESEARCH. 2020, 41(3): 213-219, [15] Yang, Qi, You, Jia, Zhou, Yuan, Wang, Yun, Pei, Rongjuan, Chen, Xinwen, Yang, Min, Chen, Jizheng. Tick-borne encephalitis virus NS4A ubiquitination antagonizes type I interferon-stimulated STAT1/2 signalling pathway. EMERGING MICROBES & INFECTIONS[J]. 2020, 9(1): 714-726, http://dx.doi.org/10.1080/22221751.2020.1745094.[16] Qing, Jie, Wu, Ming, Luo, Rui, Chen, Jizheng, Cao, Lin, Zeng, Debin, Shang, Luqing, Nong, Junxiu, Wu, Qinkai, Ding, BiSen, Chen, Xinwen, Rao, Zihe, Liu, Lei, Lou, Zhiyong. Identification of Interferon Receptor IFNAR2 As a Novel HCV Entry Factor by Using Chemical Probes. ACS CHEMICAL BIOLOGY[J]. 2020, 15(5): 1232-1241, https://www.webofscience.com/wos/woscc/full-record/WOS:000535289800016.[17] Li, Shufen, Wang, Yun, Hou, Dianhai, Guan, Zhenqiong, Shen, Shu, Peng, Ke, Deng, Fei, Chen, Xinwen, Hu, Zhihong, Wang, Hualin, Wang, Manli. Host factor heat-shock protein 90 contributes to baculovirus budded virus morphogenesis via facilitating nuclear actin polymerization. VIROLOGY[J]. 2019, 535: 200-209, http://dx.doi.org/10.1016/j.virol.2019.07.006.[18] Yang, Qi, Tang, Jielin, Pei, Rongjuan, Gao, XiaoXiao, Guo, Jing, Xu, Chonghui, Wang, Yun, Wang, Qian, Wu, Chunchen, Zhou, Yuan, Hu, Xue, Zhao, He, Wang, Yanyi, Chen, Xinwen, Chen, Jizheng. Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3. JOURNAL OF MOLECULAR CELL BIOLOGY[J]. 2019, 11(2): 158-169, http://lib.cqvip.com/Qikan/Article/Detail?id=7001603102.[19] Yang, Qi, Guo, Min, Zhou, Yuan, Hu, Xue, Wang, Yun, Wu, Chunchen, Yang, Min, Pei, Rongjuan, Chen, Xinwen, Chen, Jizheng. Phosphatidylserine-Specific Phospholipase A1 is the Critical Bridge for Hepatitis C Virus Assembly. VIROLOGICA SINICA[J]. 2019, 34(5): 521-537, http://lib.cqvip.com/Qikan/Article/Detail?id=7100604392.[20] Xianwen Zhang, Xuping Xie, Hongjie Xia, Jing Zou, Linfen Huang, Vsevolod L Popov, Xinwen Chen, PeiYong Shi. Zika Virus NS2A-Mediated Virion Assembly. MBIO[J]. 2019, 10(5): https://doaj.org/article/c5ac119523884fe89d32d02d31db3f5f.[21] Yuan, Yifei, Zhao, Kaitao, Yao, Yongxuan, Liu, Canyu, Chen, Yingshan, Li, Jing, Wang, Yun, Pei, Rongjuan, Chen, Jizheng, Hu, Xue, Zhou, Yuan, Wu, Chunchen, Chen, Xinwen. HDAC11 restricts HBV replication through epigenetic repression of cccDNA transcription. ANTIVIRAL RESEARCH[J]. 2019, 172: http://dx.doi.org/10.1016/j.antiviral.2019.104619.[22] Wu, Chunchen, Li, Baolin, Zhang, Xiaoyong, Zhao, Kaitao, Chen, Yingshan, Yuan, Yifei, Liu, Yan, Chen, Rongjuan, Xu, Dongping, Chen, Xinwen, Lu, Mengji. Complementation of Wild-Type and Drug-Resistant Hepatitis B Virus Genomes to Maintain Viral Replication and Rescue Virion Production under Nucleos(t)ide Analogs. VIROLOGICA SINICA[J]. 2019, 34(4): 377-385, http://lib.cqvip.com/Qikan/Article/Detail?id=7002861672.[23] Cao, Lin, Chen, Jizheng, Wang, Yaxin, Yang, Yuting, Qing, Jie, Rao, Zihe, Chen, Xinwen, Lou, Zhiyong. Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy. PROTEIN & CELL[J]. 2019, 10(3): 178-195, http://lib.cqvip.com/Qikan/Article/Detail?id=7001589015.[24] Chao Zhang, Xiaomei Wang, Shuran Li, Trix Twelkmeyer, Weihong Wang, Shengyuan Zhang, Shufeng Wang, Jizheng Chen, Xia Jin, Yuzhang Wu, Xinwen Chen, Shengdian Wang, Junqi Niu, Hairong Chen, Hong Tang. NKG2A is a NK cell exhaustion checkpoint for HCV persistence. NATURE COMMUNICATIONS[J]. 2019, 10(1): 1-11, http://www.corc.org.cn/handle/1471x/2373162.[25] Xie, Xuping, Zou, Jing, Zhang, Xianwen, Zhou, Yiyang, Routh, Andrew L, Kang, Congbao, Popov, Vsevolod L, Chen, Xinwen, Wang, QingYin, Dong, Hongping, Shi, PeiYong. Dengue NS2A Protein Orchestrates Virus Assembly. CELLHOSTMICROBE[J]. 2019, 26(5): 606-+, http://dx.doi.org/10.1016/j.chom.2019.09.015.[26] Lin, Yong, Wu, Chunchen, Wang, Xueyu, Liu, Shi, Kemper, Thekla, Li, Fahong, Squire, Anthony, Zhu, Ying, Zhang, Jiming, Chen, Xinwen, Lu, Mengji. Synaptosomal-associated protein 29 is required for the autophagic degradation of hepatitis B virus. FASEB JOURNAL[J]. 2019, 33(5): 6023-6034, http://dx.doi.org/10.1096/fj.201801995RR.[27] Lin, Yong, Wu, Chunchen, Wang, Xueyu, Kemper, Thekla, Squire, Anthony, Gunzer, Matthias, Zhang, Jiming, Chen, Xinwen, Lu, Mengji. Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components. PROTEIN & CELL[J]. 2019, 10(1): 60-66, http://lib.cqvip.com/Qikan/Article/Detail?id=7001589036.[28] Yao, Yongxuan, Yang, Bo, Chen, Yingshan, Wang, Hui, Hu, Xue, Zhou, Yuan, Gao, Xiuzhu, Lu, Mengji, Niu, Junqi, Wen, Zhe, Wu, Chunchen, Chen, Xinwen. RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element. JOURNAL OF VIROLOGY[J]. 2019, 93(6): http://www.corc.org.cn/handle/1471x/2373177.[29] Chen, Jizheng, Zhou, Yue, Zhuang, Yuan, Qin, Tian, Guo, Min, Jiang, Jing, Niu, Junqi, Li, John Zhong, Chen, Xinwen, Wang, Qian. The metabolic regulator small heterodimer partner contributes to the glucose and lipid homeostasis abnormalities induced by hepatitis C virus infection. METABOLISM-CLINICAL AND EXPERIMENTAL[J]. 2019, 100: http://dx.doi.org/10.1016/j.metabol.2019.153954.[30] 袁一菲, 陈新文, 吴春晨. HBV cccDNA的表观遗传学修饰及调控. 科学通报[J]. 2019, 64(30): 3084-3090, http://lib.cqvip.com/Qikan/Article/Detail?id=7100265222.[31] Bai, Huimin, Hu, Yangyang, Hu, Xue, Li, Jing, Mu, Jingfang, Zhou, Yuan, Chen, Xinwen, Wang, Yun. Major capsid protein of Autographa californica multiple nucleopolyhedrovirus contributes to the promoter activity of the very late viral genes. VIRUSRESEARCH[J]. 2019, 273: http://dx.doi.org/10.1016/j.virusres.2019.197758.[32] Zhang, Xianwen, Xie, Xuping, Zou, Jing, Xia, Hongjie, Shan, Chao, Chen, Xinwen, Shi, PeiYong. Genetic and biochemical characterizations of Zika virus NS2A protein. EMERGING MICROBES & INFECTIONS[J]. 2019, 8(1): 585-602, [33] Jizheng Chen, Yue Zhou, Yuan Zhuang, Tian Qin, Min Guo, Jing Jiang, Junqi Niu, John Zhong Li, Xinwen Chen, Qian Wang. The metabolic regulator small heterodimer partner contributes to the glucose and lipid homeostasis abnormalities induced by hepatitis C virus infection. METABOLISM. 2019, 100: http://dx.doi.org/10.1016/j.metabol.2019.153954.[34] Qi Yang, Jielin Tang, Rongjuan Pei, XiaoXiao Gao, Jing Guo, Chonghui Xu, Yun Wang, Qian Wang, Chunchen Wu, Yuan Zhou, Xue Hu, He Zhao, Yanyi Wang, Xinwen Chen, Jizheng Chen, Bing Su. Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3. JOURNAL OF MOLECULAR CELL BIOLOGY. 2018, 11(2): 158-169, [35] Kang, Yaoyue, Li, Fahong, Guo, Hongying, Yang, Sisi, Zhang, Yongmei, Zhu, Haoxiang, Wang, Jinyu, Mao, Richeng, Qin, Yanli, Xu, Jie, Chen, Xinwen, Wu, Chunchen, Zhang, Jiming. Amino acid substitutions Q129N and T131N/M133T in hepatitis B surface antigen (HBsAg) interfere with the immunogenicity of the corresponding HBsAg or viral replication ability. VIRUS RESEARCH[J]. 2018, 257: 33-39, http://dx.doi.org/10.1016/j.virusres.2018.08.019.[36] Yao, Yongxuan, Yang, Bo, Cao, Huang, Zhao, Kaitao, Yuan, Yifei, Chen, Yingshan, Zhang, Zhenhua, Wang, Yun, Pei, Rongjuan, Chen, Jizheng, Hu, Xue, Zhou, Yuan, Lu, Mengji, Wu, Chunchen, Chen, Xinwen. RBM24 stabilizes hepatitis B virus pregenomic RNA but inhibits core protein translation by targeting the terminal redundancy sequence. EMERGING MICROBES & INFECTIONS[J]. 2018, 7: http://202.127.146.157/handle/2RYDP1HH/5359.[37] Cao, Huang, Zhao, Kaitao, Yao, Yongxuan, Guo, Jing, Gao, Xiaoxiao, Yang, Qi, Guo, Min, Zhu, Wandi, Wang, Yun, Wu, Chunchen, Chen, Jizheng, Zhou, Yuan, Hu, Xue, Lu, Mengji, Chen, Xinwen, Pei, Rongjuan. RNA binding protein 24 regulates the translation and replication of hepatitis C virus. PROTEINCELL[J]. 2018, 9(11): 930-944, http://lib.cqvip.com/Qikan/Article/Detail?id=676820272.[38] Zhang, Yongli, Hu, Xue, Mu, Jingfang, Hu, Yangyang, Zhou, Yuan, Zhao, He, Wu, Chunchen, Pei, Rongjuan, Chen, Jizheng, Chen, Xinwen, Wang, Yun. Ac102 Participates in Nuclear Actin Polymerization by Modulating BV/ODV-C42 Ubiquitination during Autographa californica Multiple Nucleopolyhedrovirus Infection. JOURNAL OF VIROLOGY[J]. 2018, 92(12): http://202.127.146.157/handle/2RYDP1HH/5323.[39] Zhao, Kaitao, Liu, Shuhui, Chen, Yingshan, Yao, Yongxuan, Zhou, Ming, Yuan, Yifei, Wang, Yun, Pei, Rongjuan, Chen, Jizheng, Hu, Xue, Zhou, Yuan, Zhao, He, Lu, Mengji, Wu, Chunchen, Chen, Xinwen. Upregulation of HBV transcription by sodium taurocholate cotransporting polypeptide at the postentry step is inhibited by the entry inhibitor Myrcludex B. EMERGING MICROBES & INFECTIONS[J]. 2018, 7(1): http://www.corc.org.cn/handle/1471x/2373221.[40] Zhou, Yuan, Wang, Qian, Yang, Qi, Tang, Jielin, Xu, Chonghui, Gai, Dongwei, Chen, Xinwen, Chen, Jizheng. Histone Deacetylase 3 Inhibitor Suppresses Hepatitis C Virus Replication by Regulating Apo-A1 and LEAP-1 Expression. VIROLOGICA SINICA[J]. 2018, 33(5): 418-428, http://lib.cqvip.com/Qikan/Article/Detail?id=6100074072.[41] Deng, Liu, Cao, Liang, Chen, Yingshan, Chen, Jizheng, Hu, Xue, Chen, Xinwen, Wu, Chunchen, Zhou, Yuan. Hepatitis B surface antigen with N-terminal addition of mCherry can assemble into functional subviral particles. FUTURE VIROLOGY[J]. 2018, 13(11): 769-778, http://202.127.146.157/handle/2RYDP1HH/6330.[42] Kaitao Zhao, Shuhui Liu, Yingshan Chen, Yongxuan Yao, Ming Zhou, Yifei Yuan, Yun Wang, Rongjuan Pei, Jizheng Chen, Xue Hu, Yuan Zhou, He Zhao, Mengji Lu, Chunchen Wu, Xinwen Chen. Upregulation of HBV transcription by sodium taurocholate cotransporting polypeptide at the postentrystep is inhibited by the entry inhibitor Myrcludex B. EMERGING MICROBES AND INFECTIONS[J]. 2018, 7(1): 1-14, http://www.corc.org.cn/handle/1471x/2373221.[43] Huang Cao, Kaitao Zhao, Yongxuan Yao, Jing Guo, Xiaoxiao Gao, Qi Yang, Min Guo, Mengji Lut, Xinwen Chen, Rongjuan Pei. RNA binding protein 24 regulates the translation and replication of hepatitis C virus. 蛋白质与细胞：英文版[J]. 2018, 9(11): 930-944, http://lib.cqvip.com/Qikan/Article/Detail?id=676820272.[44] Zhang, Huixia, Zhang, Chao, Tang, Hong, Gao, Shanshan, Sun, Fang, Yang, Yuan, Zhou, Weiping, Hu, Yu, Ke, Changshu, Wu, Yu, Ding, Zeyang, Guo, Lin, Pei, Rongjuan, Chen, Xinwen, Sy, ManSun, Zhang, Bixiang, Li, Chaoyang. CD2-Associated Protein Contributes to Hepatitis C, Virus Propagation and Steatosis by Disrupting Insulin Signaling. HEPATOLOGY[J]. 2018, 68(5): 1710-1725, http://www.corc.org.cn/handle/1471x/2373230.[45] Lin Cao, Jizheng Chen, Yaxin Wang, Yuting Yang, Jie Qing, Zihe Rao, Xinwen Chen, Zhiyong Lou. Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy. 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SeMNPV抑制HaSNPV诱导的Se—UCR细胞凋亡. 中国病毒学[J]. 2003, 18(6): 587-592, http://lib.cqvip.com/Qikan/Article/Detail?id=9014242.[175] 侯松旺, 陈新文, 王汉中, 胡志红. 一种以PCR产物直接构建同源重组杆状病毒的方法. 中国科学：C辑[J]. 2003, 33(2): 169-174, http://lib.cqvip.com/Qikan/Article/Detail?id=8077817.[176] 梁昌镛, He Bin, 胡志红, 王汉中, 陈新文. 丙型肝炎病毒NS5A基因的克隆以及在原核和昆虫细胞中表达的研究. 华中师范大学学报：自然科学版[J]. 2003, 37(2): 236-241, http://lib.cqvip.com/Qikan/Article/Detail?id=8073951.[177] 侯松旺, 陈新文, 王汉中, 胡志红. 一种以PCR产物直接构建同源重组杆状病毒的方法. 中国科学：C辑[J]. 2003, 33(2): 169-174, http://lib.cqvip.com/Qikan/Article/Detail?id=8077817.[178] 吴东, 王华林, 邓菲, 陈新文, 彭辉银, 胡志红. 棉铃虫单核衣壳核多角体病毒几丁质酶基因的克隆与表达. 中国病毒学[J]. 2002, 17(4): 331-335, http://lib.cqvip.com/Qikan/Article/Detail?id=7140814.[179] 王汉中, 黄弋, 司艳红, 方明刚, 陈新文, Just M Vlak, 胡志红. 一种新颖的棉铃虫单闰包埋核多角体病毒表达系统. 中国病毒学[J]. 2002, 17(4): 319-325, http://lib.cqvip.com/Qikan/Article/Detail?id=7140812.[180] 牟春燕, 余泽华, 王颖, 陈新文, 胡志红. 含果蝇肌动蛋白基因的重组棉铃虫核型多角体病毒的构建. 华中师范大学学报：自然科学版[J]. 2002, 36(1): 76-79, http://lib.cqvip.com/Qikan/Article/Detail?id=6078962.[181] 陈新文, 胡志红, 吴东, Just M Vlak. 棉铃虫单核衣壳核多角体病毒囊膜蛋白odv—e66基因及其邻近区域的序列分析. 中国病毒学[J]. 2001, 16(4): 330-, http://lib.cqvip.com/Qikan/Article/Detail?id=5744331.[182] Vlak J M, 胡志红, 王华林, 陈新文. 棉铃虫核多角体病毒p10基因的序列及转录分析. 病毒学报[J]. 2001, 17(1): 81-, http://lib.cqvip.com/Qikan/Article/Detail?id=5015510.[183] Just M Vlak, 陈新文, 胡志红, 范凌云. 棉铃虫单核衣壳核多角体病毒解螺旋酶基因的序列分析. 中国病毒学[J]. 2001, 16(4): 344-, http://lib.cqvip.com/Qikan/Article/Detail?id=5744334.[184] 方明刚, 王汉中, 胡志红, Just M Vlak, 陈新文. 棉铃虫单核衣壳核多角体病毒（HaSNPV）Hind III-L片段的序列分析. 中国病毒学[J]. 2001, 16(4): 355-, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=832782&detailType=1.[185] 龙钢, 胡志红, Just M Vlak, 陈新文. 中国棉铃虫单粒包埋核多角体病毒（HaSNPV）HindⅢ—Ⅰ片段的序列分析与基因排列研究. 病毒学报[J]. 2001, 17(2): 150-, http://lib.cqvip.com/Qikan/Article/Detail?id=5310767.[186] 刘岚, 陈新文, Basil M Arif, 胡志红, Hilary Lauzon, 孙修炼, Just M Vlak. 棉铃虫单核衣壳核多角体病毒组织蛋白酶基因的序列分析和进化研究. 中国病毒学[J]. 2001, 16(3): 229-, http://lib.cqvip.com/Qikan/Article/Detail?id=5530430.[187] 陈新文, 周志艳. 素质教育的理性批判. 教学与管理[J]. 2000, 12-14, http://lib.cqvip.com/Qikan/Article/Detail?id=4719111.[188] 罗保君, 陈新文, Valk Just M, 彭辉银, Arif Basil M, 胡志红, 王汉中, 王华林, 孙修炼. 油桐尺蠖单粒包埋核型多角体病毒（BusuNPV）BamHI—H片段的序列分析. 中国病毒学[J]. 1999, 14(4): 333-, http://lib.cqvip.com/Qikan/Article/Detail?id=4022975.[189] Basil M Arif, 彭辉银, 张双民, 陈新文, 胡志红, 李星. 中国棉铃虫核型多角体病毒几丁质酶基因的定位与克隆. 中国病毒学[J]. 1998, 13(2): 139-, http://lib.cqvip.com/Qikan/Article/Detail?id=2930626.[190] 沈瑞菊, 彭辉银, 胡志红, 周显明, 陈新文, 姜芸. 松毛虫赤眼蜂携带质型多角体病毒防治马尾松毛虫. 中国生物防治[J]. 1998, 14(3): 111-, http://lib.cqvip.com/Qikan/Article/Detail?id=3218554.[191] 陈新文, 胡志红. 中国棉铃虫单粒包埋核型多角体病毒多角体蛋白基因的序列分析. 中国病毒学[J]. 1997, 12(4): 346-, http://lib.cqvip.com/Qikan/Article/Detail?id=2763150.[192] 彭辉银, 陈新文, 张忠信, 张光裕. 棉铃虫核型多角体病毒在生态环境中的滞留及作用. 中国病毒学[J]. 1995, 10(1): 56-, http://lib.cqvip.com/Qikan/Article/Detail?id=1956007.[193] 彭辉银, 周显明, 陈新文, 谢天恩, 李崇荣. 柏毒蛾核型多角体病毒的分离鉴定. 中国病毒学[J]. 1994, 9(1): 74-, http://lib.cqvip.com/Qikan/Article/Detail?id=1551540.[194] 谢天恩, 彭辉银, 陈世维, 刘润忠, 陈新文. 文山松毛虫质型多角体病毒形态结构及理化性质的研究. 中国病毒学[J]. 1992, 7(1): 69-, http://lib.cqvip.com/Qikan/Article/Detail?id=938095.[195] 陈新文, 郭亨孝. 蜀柏毒蛾核型多角体病毒的分离鉴定. 中国病毒学[J]. 1991, 6(4): 379-380, http://lib.cqvip.com/Qikan/Article/Detail?id=5310786.
发表著作
（1） 病毒的起源与进化，Origin and Evolution of Viruses，科学出版社，2009-04，第1作者
（2） 昆虫病毒分子生物学，Molecular biology of insect virus, Advances in microbial control of insect pests，Kluwer Academic/Plenum Publisher, New York，2003-01，第2作者
（2） 昆虫病毒分子生物学，Molecular biology of insect virus, Advances in microbial control of insect pests，Kluwer Academic/Plenum Publisher, New York，2003-01，第2作者
科研活动
科研项目
（1） 病毒性肝炎树鼩模型，参与，院级级，2011-01--2014-06
（2） 肌动蛋白聚合分子机制，主持，国家级，2010-07--2012-12
（3） 新发传染病流行规律研究，参与，国家级，2010-06--2012-06
（4） 参与HCV翻译调控的宿主信号通路，参与，国家级，2009-01--2013-12
（5） 杆状病毒分子机理，参与，国家级，2009-01--2013-12
（6） HCV对肿瘤细胞的调控，参与，国家级，2009-01--2012-12
（7） 肝炎病毒相关的蛋白质和代谢组NMR方法研究，参与，院级级，2008-01--2011-12
（2） 肌动蛋白聚合分子机制，主持，国家级，2010-07--2012-12
（3） 新发传染病流行规律研究，参与，国家级，2010-06--2012-06
（4） 参与HCV翻译调控的宿主信号通路，参与，国家级，2009-01--2013-12
（5） 杆状病毒分子机理，参与，国家级，2009-01--2013-12
（6） HCV对肿瘤细胞的调控，参与，国家级，2009-01--2012-12
（7） 肝炎病毒相关的蛋白质和代谢组NMR方法研究，参与，院级级，2008-01--2011-12
指导学生
已指导学生
王云 博士研究生 071005-微生物学
李祥 博士研究生 071005-微生物学
梁昌镛 博士研究生 071005-微生物学
曾宪东 博士研究生 071005-微生物学
李莉娟 博士研究生 071005-微生物学
姚相杰 博士研究生 071005-微生物学
黎炎梅 博士研究生 071005-微生物学
宋建华 博士研究生 071005-微生物学
李肖莉 硕士研究生 071010-生物化学与分子生物学
马佳 硕士研究生 071010-生物化学与分子生物学
王瑞青 硕士研究生 071010-生物化学与分子生物学
刘超红 硕士研究生 071010-生物化学与分子生物学
姜婷 硕士研究生 071010-生物化学与分子生物学
李世兴 硕士研究生 071010-生物化学与分子生物学
南方 硕士研究生 071010-生物化学与分子生物学
彭颖 博士研究生 071005-微生物学
吴春晨 博士研究生 071005-微生物学
韩庆霞 博士研究生 071005-微生物学
王倩 博士研究生 071005-微生物学
刘萍萍 博士研究生 071005-微生物学
李妮 硕士研究生 071010-生物化学与分子生物学
邱健 硕士研究生 071010-生物化学与分子生物学
徐松 博士研究生 071005-微生物学
裴荣娟 博士研究生 071005-微生物学
朱文博 博士研究生 071005-微生物学
吕一品 硕士研究生 071010-生物化学与分子生物学
石慧 硕士研究生 071010-生物化学与分子生物学
许春莲 硕士研究生 071010-生物化学与分子生物学
卿杰 硕士研究生 071010-生物化学与分子生物学
耿婷 硕士研究生 071010-生物化学与分子生物学
钦博 博士研究生 071010-生物化学与分子生物学
李坤 博士研究生 071010-生物化学与分子生物学
白慧敏 博士研究生 071010-生物化学与分子生物学
邓万玉 硕士研究生 071010-生物化学与分子生物学
甘小妮 博士研究生 071010-生物化学与分子生物学
邓柳 硕士研究生 071010-生物化学与分子生物学
现指导学生
陈继征 博士研究生 071010-生物化学与分子生物学
陈红贺 博士研究生 071010-生物化学与分子生物学
赵瀚 硕士研究生 071010-生物化学与分子生物学
赖娟 硕士研究生 071010-生物化学与分子生物学
李松侠 硕士研究生 071010-生物化学与分子生物学
朱婉迪 博士研究生 071010-生物化学与分子生物学
曹亮 博士研究生 071010-生物化学与分子生物学
苏玺 硕士研究生 071005-微生物学
王惠 硕士研究生 071005-微生物学
郭敏 博士研究生 071010-生物化学与分子生物学
曹璜 博士研究生 071010-生物化学与分子生物学
穆敬芳 博士研究生 071010-生物化学与分子生物学