基本信息

张义兵 男 博导 中国科学院水生生物研究所
电子邮件: ybzhang@ihb.ac.cn
通信地址: 中国科学院水生生物研究所
邮政编码: 430072
电子邮件: ybzhang@ihb.ac.cn
通信地址: 中国科学院水生生物研究所
邮政编码: 430072
招生信息
招生专业
100102-免疫学
090801-水产养殖
090801-水产养殖
招生方向
抗病毒感染免疫学
抗病毒因子的功能及应用
脊椎动物免疫系统发育及分子进化
抗病毒因子的功能及应用
脊椎动物免疫系统发育及分子进化
教育背景
2007-12--2008-12 美国UT MD Anderson Cancer Center 访问学者
2000-09--2003-06 中国科学院水生生物研究所 理学博士
1993-09--1996-08 中国科学院水生生物研究所 理学硕士
1987-08--1991-06 湖北大学生物学系 理学学士
2000-09--2003-06 中国科学院水生生物研究所 理学博士
1993-09--1996-08 中国科学院水生生物研究所 理学硕士
1987-08--1991-06 湖北大学生物学系 理学学士
工作经历
工作简历
2009-07~现在, 中国科学院水生生物研究所, 研究员
2004-01~2009-07,中国科学院水生生物研究所, 副研究员
1997-08~2003-12,中国科学院水生生物研究所, 助理研究员
1996-08~1997-08,中国科学院水生生物研究所, 研究实习员
1992-09~1993-08,湖北省仙桃市第一中学, 中学教师二级
1991-07~1992-08,湖北省仙桃市第五中学, 中学教师三级
2004-01~2009-07,中国科学院水生生物研究所, 副研究员
1997-08~2003-12,中国科学院水生生物研究所, 助理研究员
1996-08~1997-08,中国科学院水生生物研究所, 研究实习员
1992-09~1993-08,湖北省仙桃市第一中学, 中学教师二级
1991-07~1992-08,湖北省仙桃市第五中学, 中学教师三级
教授课程
水产病害防控及免疫学
发育生物学
水产病害防控与免疫学
发育生物学
水产病害防控与免疫学
专利与奖励
奖励信息
(1) 水产动物不同病毒基因组解析及病毒与宿主相互作用的分子机制, 二等奖, 省级, 2017
出版信息
发表论文
[1] Journal of Virology. 2024, 通讯作者
[2] Iscience. 2024, 通讯作者
[3] 水生生物学报. 2023, 通讯作者
[4] Int J Mol Sci.. 2023, 通讯作者
[5] Water Biology and Security. 2023, 通讯作者
[6] Dev Comp Immunol. 2023, 通讯作者
[7] Iscience. 2022, 通讯作者
[8] Dev Comp Immunol. 2022, 通讯作者
[9] Frontiers in Immunology. 2022, 通讯作者
[10] Journal of Immunology. 2022, 通讯作者
[11] Star Protocols. 2022, 通讯作者
[12] Journal of Immunology. 2022, 通讯作者
[13] Frontiers in Immunology. 2022, 通讯作者
[14] 水产学报. 2021, 通讯作者
[15] Zang, ZhaoXing, Dan, Cheng, Zhou, Li, Zhang, QiYa, Gui, JianFang, Zhang, YiBing. Function characterization and expression regulation of two different-sized 3 ' untranslated region-containing interferon genes from clone F of gibel carp Carassius auratus gibelio. MOLECULAR IMMUNOLOGY[J]. 2020, 第 6 作者 通讯作者 119(1): 18-26, http://dx.doi.org/10.1016/j.molimm.2020.01.004.
[16] Chuxin Wu, Yibing Zhang, Chengyu Hu. PKZ, a Fish-Unique eIF2α Kinase Involved in Innate Immune Response. FRONTIERS IN IMMUNOLOGY[J]. 2020, 第 2 作者11: https://doaj.org/article/b790c5ddda69482ab10d3b45c5fbc145.
[17] Xiong, Yang, Dan, Cheng, Ren, Fan, Su, ZiHao, Zhang, Yibing, Mei, Jie. Proteomic profiling of yellow catfish (Pelteobagrus fulvidraco) skin mucus identifies differentially-expressed proteins in response to Edwardsiella ictaluri infection. FISH & SHELLFISH IMMUNOLOGY[J]. 2020, 第 5 作者 通讯作者 100: 98-108, http://dx.doi.org/10.1016/j.fsi.2020.02.059.
[18] 张义兵. Characterization of DNA binding and nuclear retention identifies zebrafish-specific IRF11 as a positive regulator of IFN antiviral response. Journal of Immunology. 2020, 第 1 作者 通讯作者
[19] Gong, XiuYing, Zhang, QiMin, Gui, JianFang, Zhang, YiBing. SVCV infection triggers fish IFN response through RLR signaling pathway. FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 第 4 作者 通讯作者 86: 1058-1063, http://dx.doi.org/10.1016/j.fsi.2018.12.063.
[20] Wu, Min, Dan, Cheng, Gui, JianFang, Zhang, YiBing. Fish species-specific TRIM gene FTRCA1 negatively regulates interferon response through attenuating IRF7 transcription. FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 第 4 作者 通讯作者 90(1): 180-187, http://dx.doi.org/10.1016/j.fsi.2019.04.297.
[21] 张义兵. FTRCA1, a species-specific member of finTRIM family, negatively regulates fish interferon response through autophage-lysosomal degradation of TBK1. Journal of Immunology. 2019, 第 1 作者 通讯作者
[22] 张义兵. Alternative splicing transcripts of zebrafish LGP2 gene differentially contributes to interferon antiviral response. Journal of Immunology. 2018, 第 1 作者 通讯作者
[23] ByungSeok Kim, Huiping Lu, Kenji Ichiyama, Xiang Chen, YiBing Zhang, Nipun A Mistry, Kentaro Tanaka, Younghee Lee, Roza Nurieva, Li Zhang, Xuexian Yang, Yeonseok Chung, Wei Jin, Seon Hee Chang, Chen Dong. Generation of RORγt+ Antigen-Specific T Regulatory 17 Cells from Foxp3+ Precursors in Autoimmunity. CELL REPORTS[J]. 2017, 第 5 作者21(1): 195-207, http://dx.doi.org/10.1016/j.celrep.2017.09.021.
[24] 桂建芳, 张义兵, 熊亚玮. 斑马鱼IRF11基因的鉴定、亚细胞定位及表达特征. 水生生物学报[J]. 2017, 第 2 作者41(1): 1, http://lib.cqvip.com/Qikan/Article/Detail?id=671115015.
[25] Feng, Hui, Zhang, QiMin, Zhang, YiBing, Li, Zhi, Zhang, Jun, Xiong, YaWei, Wu, Min, Gui, JianFang. Zebrafish IRF1, IRF3, and IRF7 Differentially Regulate IFN Phi 1 and IFN Phi 3 Expression through Assembly of Homo- or Heteroprotein Complexes. JOURNAL OF IMMUNOLOGY[J]. 2016, 第 3 作者 通讯作者 197(5): 1893-1904, https://www.webofscience.com/wos/woscc/full-record/WOS:000385002300037.
[26] 张义兵. Zebrafish IRF1 regulates IFN antiviral response through binding to IFNphil1 and IFNphil3 promoters downstream of MyD88 signaling. Journal of Immunology. 2015, 第 1 作者
[27] Chen, Chen, Zhang, YiBing, Gui, JianFang. Expression characterization, genomic structure and function analysis of fish ubiquitin-specific protease 18 (USP18) genes. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2015, 第 2 作者 通讯作者 52(2): 112-122, http://dx.doi.org/10.1016/j.dci.2015.05.003.
[28] Jun Zhang, Yi-Bing Zhang, Min Wu, Bing Wang, Chen Chen, Jian-Fang Gui. Fish MAVS is involved in RLR pathway-mediated IFN response. FISH AND SHELLFISH IMMUNOLOGY. 2014, 第 2 作者41(2): 222-230, http://dx.doi.org/10.1016/j.fsi.2014.09.002.
[29] Bing Wang, Yi-Bing Zhang, Ting-Kai Liu, Jian-Fang Gui. Sequence analysis and subcellular localization of crucian carp Carassius auratus viperin. FISH AND SHELLFISH IMMUNOLOGY. 2014, 第 2 作者39(2): 168-177, http://dx.doi.org/10.1016/j.fsi.2014.04.025.
[30] Wang, Bing, Zhang, YiBing, Liu, TingKai, Shi, Jun, Sun, Fan, Gui, JianFang. Fish viperin exerts a conserved antiviral function through RLR-triggered IFN signaling pathway. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2014, 第 2 作者 通讯作者 47(1): 140-149, http://dx.doi.org/10.1016/j.dci.2014.07.006.
[31] 桂建芳. Gig1, a novel antiviral effector involved in fish interferon response. VIROLOGY[J]. 2014, 448(-): 322-332, http://dx.doi.org/10.1016/j.virol.2013.10.029.
[32] 桂建芳. Identification of a novel Gig2 gene family specific to non-amniote vertebrates. PLOSONE[J]. 2013, 8(4): e60588, https://doaj.org/article/0ba4f544e0af44c18745f158c16e21a4.
[33] 桂建芳. Expression regulation of zebrafish interferon regulatory factor 9 by promoter analysis. DEVELOPMENTAL & COMPARATIVE IMMUNOLOGY. 2013, 41(4): 534-543,
[34] 桂建芳. Lineage-specific expansion of IFIT gene family: an insight into coevolution with IFN gene family. PLOSONE[J]. 2013, 8(6): e66859, https://doaj.org/article/cee11146eef849439cabad870e68e507.
[35] 桂建芳. Molecular regulation of interferon antiviral response in fish (review). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2012, 38(2): 193-202, http://www.irgrid.ac.cn/handle/1471x/533530.
[36] Li, Shun, Sun, Fan, Zhang, YiBing, Gui, JianFang, Zhang, QiYa. Identification of DreI as an Antiviral Factor Regulated by RLR Signaling Pathway. PLOS ONE[J]. 2012, 第 3 作者7(3): http://www.irgrid.ac.cn/handle/1471x/495353.
[37] 刘颖, 张义兵, 刘庭凯, 桂建芳. 斑马鱼一个IFIT家族基因的鉴定及启动子分析. 水生生物学报[J]. 2012, 第 2 作者36(1): 1-8, http://lib.cqvip.com/Qikan/Article/Detail?id=40811923.
[38] Wang, Xiaohu, Zhang, Yibing, Yang, Xuexian O, Nurieva, Roza I, Chang, Seon Hee, Ojeda, Sandra S, Kang, Hong S, Schluns, Kimberly S, Gui, Jianfang, Jetten, Anton M, Dong, Chen. Transcription of Il17 and Il17f Is Controlled by Conserved Noncoding Sequence 2. IMMUNITY[J]. 2012, 第 2 作者36(1): 23-31, http://dx.doi.org/10.1016/j.immuni.2011.10.019.
[39] Jun Shi, Yi-Bing Zhang, Ting-Kai Liu, Fan Sun, Jian-Fang Gui. Subcellular localization and functional characterization of a fish IRF9 from crucian carp Carassius auratus. FISH AND SHELLFISH IMMUNOLOGY. 2012, 第 2 作者33(2): 258-266, http://dx.doi.org/10.1016/j.fsi.2012.05.014.
[40] Liu, TingKai, Zhang, YiBing, Liu, Ying, Sun, Fan, Gui, JianFang. Cooperative Roles of Fish Protein Kinase Containing Z-DNA Binding Domains and Double-Stranded RNA-Dependent Protein Kinase in Interferon-Mediated Antiviral Response. JOURNAL OF VIROLOGY[J]. 2011, 第 2 作者 通讯作者 85(23): 12769-12780, http://www.irgrid.ac.cn/handle/1471x/335974.
[41] Sun, Fan, Zhang, YiBing, Liu, TingKai, Shi, Jun, Wang, Bing, Gui, JianFang. Fish MITA Serves as a Mediator for Distinct Fish IFN Gene Activation Dependent on IRF3 or IRF7. JOURNAL OF IMMUNOLOGY[J]. 2011, 第 2 作者 通讯作者 187(5): 2531-2539, http://dx.doi.org/10.4049/jimmunol.1100642.
[42] 张义兵, 桂建芳. 鱼类干扰素反应及分子调控. 生物工程学报[J]. 2011, 第 1 作者27(5): 675-683, http://lib.cqvip.com/Qikan/Article/Detail?id=37994739.
[43] 张义兵. Characterization of fish IRF3 as an IFN-inducible protein reveals evolving regulation of IFN response in vertebrates. Journal of Immunology. Journal of Immunology. 2010, 第 1 作者
[44] Yu, FeiFei, Zhang, YiBing, Liu, TingKai, Liu, Ying, Sun, Fan, Jiang, Jun, Gui, JianFang. Fish virus-induced interferon exerts antiviral function through Stat1 pathway. MOLECULAR IMMUNOLOGY[J]. 2010, 第 2 作者47(14): 2330-2341, http://dx.doi.org/10.1016/j.molimm.2010.05.282.
[45] 甘力, 张义兵, 孙钒, 桂建芳. 鲫Nub1基因的克隆及特征分析. 水生生物学报[J]. 2010, 第 2 作者34(4): 702-708, http://lib.cqvip.com/Qikan/Article/Detail?id=34898114.
[2] Iscience. 2024, 通讯作者
[3] 水生生物学报. 2023, 通讯作者
[4] Int J Mol Sci.. 2023, 通讯作者
[5] Water Biology and Security. 2023, 通讯作者
[6] Dev Comp Immunol. 2023, 通讯作者
[7] Iscience. 2022, 通讯作者
[8] Dev Comp Immunol. 2022, 通讯作者
[9] Frontiers in Immunology. 2022, 通讯作者
[10] Journal of Immunology. 2022, 通讯作者
[11] Star Protocols. 2022, 通讯作者
[12] Journal of Immunology. 2022, 通讯作者
[13] Frontiers in Immunology. 2022, 通讯作者
[14] 水产学报. 2021, 通讯作者
[15] Zang, ZhaoXing, Dan, Cheng, Zhou, Li, Zhang, QiYa, Gui, JianFang, Zhang, YiBing. Function characterization and expression regulation of two different-sized 3 ' untranslated region-containing interferon genes from clone F of gibel carp Carassius auratus gibelio. MOLECULAR IMMUNOLOGY[J]. 2020, 第 6 作者 通讯作者 119(1): 18-26, http://dx.doi.org/10.1016/j.molimm.2020.01.004.
[16] Chuxin Wu, Yibing Zhang, Chengyu Hu. PKZ, a Fish-Unique eIF2α Kinase Involved in Innate Immune Response. FRONTIERS IN IMMUNOLOGY[J]. 2020, 第 2 作者11: https://doaj.org/article/b790c5ddda69482ab10d3b45c5fbc145.
[17] Xiong, Yang, Dan, Cheng, Ren, Fan, Su, ZiHao, Zhang, Yibing, Mei, Jie. Proteomic profiling of yellow catfish (Pelteobagrus fulvidraco) skin mucus identifies differentially-expressed proteins in response to Edwardsiella ictaluri infection. FISH & SHELLFISH IMMUNOLOGY[J]. 2020, 第 5 作者 通讯作者 100: 98-108, http://dx.doi.org/10.1016/j.fsi.2020.02.059.
[18] 张义兵. Characterization of DNA binding and nuclear retention identifies zebrafish-specific IRF11 as a positive regulator of IFN antiviral response. Journal of Immunology. 2020, 第 1 作者 通讯作者
[19] Gong, XiuYing, Zhang, QiMin, Gui, JianFang, Zhang, YiBing. SVCV infection triggers fish IFN response through RLR signaling pathway. FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 第 4 作者 通讯作者 86: 1058-1063, http://dx.doi.org/10.1016/j.fsi.2018.12.063.
[20] Wu, Min, Dan, Cheng, Gui, JianFang, Zhang, YiBing. Fish species-specific TRIM gene FTRCA1 negatively regulates interferon response through attenuating IRF7 transcription. FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 第 4 作者 通讯作者 90(1): 180-187, http://dx.doi.org/10.1016/j.fsi.2019.04.297.
[21] 张义兵. FTRCA1, a species-specific member of finTRIM family, negatively regulates fish interferon response through autophage-lysosomal degradation of TBK1. Journal of Immunology. 2019, 第 1 作者 通讯作者
[22] 张义兵. Alternative splicing transcripts of zebrafish LGP2 gene differentially contributes to interferon antiviral response. Journal of Immunology. 2018, 第 1 作者 通讯作者
[23] ByungSeok Kim, Huiping Lu, Kenji Ichiyama, Xiang Chen, YiBing Zhang, Nipun A Mistry, Kentaro Tanaka, Younghee Lee, Roza Nurieva, Li Zhang, Xuexian Yang, Yeonseok Chung, Wei Jin, Seon Hee Chang, Chen Dong. Generation of RORγt+ Antigen-Specific T Regulatory 17 Cells from Foxp3+ Precursors in Autoimmunity. CELL REPORTS[J]. 2017, 第 5 作者21(1): 195-207, http://dx.doi.org/10.1016/j.celrep.2017.09.021.
[24] 桂建芳, 张义兵, 熊亚玮. 斑马鱼IRF11基因的鉴定、亚细胞定位及表达特征. 水生生物学报[J]. 2017, 第 2 作者41(1): 1, http://lib.cqvip.com/Qikan/Article/Detail?id=671115015.
[25] Feng, Hui, Zhang, QiMin, Zhang, YiBing, Li, Zhi, Zhang, Jun, Xiong, YaWei, Wu, Min, Gui, JianFang. Zebrafish IRF1, IRF3, and IRF7 Differentially Regulate IFN Phi 1 and IFN Phi 3 Expression through Assembly of Homo- or Heteroprotein Complexes. JOURNAL OF IMMUNOLOGY[J]. 2016, 第 3 作者 通讯作者 197(5): 1893-1904, https://www.webofscience.com/wos/woscc/full-record/WOS:000385002300037.
[26] 张义兵. Zebrafish IRF1 regulates IFN antiviral response through binding to IFNphil1 and IFNphil3 promoters downstream of MyD88 signaling. Journal of Immunology. 2015, 第 1 作者
[27] Chen, Chen, Zhang, YiBing, Gui, JianFang. Expression characterization, genomic structure and function analysis of fish ubiquitin-specific protease 18 (USP18) genes. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2015, 第 2 作者 通讯作者 52(2): 112-122, http://dx.doi.org/10.1016/j.dci.2015.05.003.
[28] Jun Zhang, Yi-Bing Zhang, Min Wu, Bing Wang, Chen Chen, Jian-Fang Gui. Fish MAVS is involved in RLR pathway-mediated IFN response. FISH AND SHELLFISH IMMUNOLOGY. 2014, 第 2 作者41(2): 222-230, http://dx.doi.org/10.1016/j.fsi.2014.09.002.
[29] Bing Wang, Yi-Bing Zhang, Ting-Kai Liu, Jian-Fang Gui. Sequence analysis and subcellular localization of crucian carp Carassius auratus viperin. FISH AND SHELLFISH IMMUNOLOGY. 2014, 第 2 作者39(2): 168-177, http://dx.doi.org/10.1016/j.fsi.2014.04.025.
[30] Wang, Bing, Zhang, YiBing, Liu, TingKai, Shi, Jun, Sun, Fan, Gui, JianFang. Fish viperin exerts a conserved antiviral function through RLR-triggered IFN signaling pathway. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2014, 第 2 作者 通讯作者 47(1): 140-149, http://dx.doi.org/10.1016/j.dci.2014.07.006.
[31] 桂建芳. Gig1, a novel antiviral effector involved in fish interferon response. VIROLOGY[J]. 2014, 448(-): 322-332, http://dx.doi.org/10.1016/j.virol.2013.10.029.
[32] 桂建芳. Identification of a novel Gig2 gene family specific to non-amniote vertebrates. PLOSONE[J]. 2013, 8(4): e60588, https://doaj.org/article/0ba4f544e0af44c18745f158c16e21a4.
[33] 桂建芳. Expression regulation of zebrafish interferon regulatory factor 9 by promoter analysis. DEVELOPMENTAL & COMPARATIVE IMMUNOLOGY. 2013, 41(4): 534-543,
[34] 桂建芳. Lineage-specific expansion of IFIT gene family: an insight into coevolution with IFN gene family. PLOSONE[J]. 2013, 8(6): e66859, https://doaj.org/article/cee11146eef849439cabad870e68e507.
[35] 桂建芳. Molecular regulation of interferon antiviral response in fish (review). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2012, 38(2): 193-202, http://www.irgrid.ac.cn/handle/1471x/533530.
[36] Li, Shun, Sun, Fan, Zhang, YiBing, Gui, JianFang, Zhang, QiYa. Identification of DreI as an Antiviral Factor Regulated by RLR Signaling Pathway. PLOS ONE[J]. 2012, 第 3 作者7(3): http://www.irgrid.ac.cn/handle/1471x/495353.
[37] 刘颖, 张义兵, 刘庭凯, 桂建芳. 斑马鱼一个IFIT家族基因的鉴定及启动子分析. 水生生物学报[J]. 2012, 第 2 作者36(1): 1-8, http://lib.cqvip.com/Qikan/Article/Detail?id=40811923.
[38] Wang, Xiaohu, Zhang, Yibing, Yang, Xuexian O, Nurieva, Roza I, Chang, Seon Hee, Ojeda, Sandra S, Kang, Hong S, Schluns, Kimberly S, Gui, Jianfang, Jetten, Anton M, Dong, Chen. Transcription of Il17 and Il17f Is Controlled by Conserved Noncoding Sequence 2. IMMUNITY[J]. 2012, 第 2 作者36(1): 23-31, http://dx.doi.org/10.1016/j.immuni.2011.10.019.
[39] Jun Shi, Yi-Bing Zhang, Ting-Kai Liu, Fan Sun, Jian-Fang Gui. Subcellular localization and functional characterization of a fish IRF9 from crucian carp Carassius auratus. FISH AND SHELLFISH IMMUNOLOGY. 2012, 第 2 作者33(2): 258-266, http://dx.doi.org/10.1016/j.fsi.2012.05.014.
[40] Liu, TingKai, Zhang, YiBing, Liu, Ying, Sun, Fan, Gui, JianFang. Cooperative Roles of Fish Protein Kinase Containing Z-DNA Binding Domains and Double-Stranded RNA-Dependent Protein Kinase in Interferon-Mediated Antiviral Response. JOURNAL OF VIROLOGY[J]. 2011, 第 2 作者 通讯作者 85(23): 12769-12780, http://www.irgrid.ac.cn/handle/1471x/335974.
[41] Sun, Fan, Zhang, YiBing, Liu, TingKai, Shi, Jun, Wang, Bing, Gui, JianFang. Fish MITA Serves as a Mediator for Distinct Fish IFN Gene Activation Dependent on IRF3 or IRF7. JOURNAL OF IMMUNOLOGY[J]. 2011, 第 2 作者 通讯作者 187(5): 2531-2539, http://dx.doi.org/10.4049/jimmunol.1100642.
[42] 张义兵, 桂建芳. 鱼类干扰素反应及分子调控. 生物工程学报[J]. 2011, 第 1 作者27(5): 675-683, http://lib.cqvip.com/Qikan/Article/Detail?id=37994739.
[43] 张义兵. Characterization of fish IRF3 as an IFN-inducible protein reveals evolving regulation of IFN response in vertebrates. Journal of Immunology. Journal of Immunology. 2010, 第 1 作者
[44] Yu, FeiFei, Zhang, YiBing, Liu, TingKai, Liu, Ying, Sun, Fan, Jiang, Jun, Gui, JianFang. Fish virus-induced interferon exerts antiviral function through Stat1 pathway. MOLECULAR IMMUNOLOGY[J]. 2010, 第 2 作者47(14): 2330-2341, http://dx.doi.org/10.1016/j.molimm.2010.05.282.
[45] 甘力, 张义兵, 孙钒, 桂建芳. 鲫Nub1基因的克隆及特征分析. 水生生物学报[J]. 2010, 第 2 作者34(4): 702-708, http://lib.cqvip.com/Qikan/Article/Detail?id=34898114.
科研活动
科研项目
( 1 ) 鱼类抗病基因调控网络和分子设计育种的基础研究, 参与, 国家任务, 2010-01--2014-06
( 2 ) 重要性状基因功能快速验证动物模型和技术平台的建立及其应用, 参与, 国家任务, 2010-01--2011-12
( 3 ) 不同斑马鱼干扰素基因的诱导表达及比较研究, 负责人, 国家任务, 2012-01--2012-12
( 4 ) 鱼类特有基因Gig1和Gig2在干扰素抗病毒反应中的功能研究, 负责人, 国家任务, 2013-01--2016-12
( 5 ) 鲤抗病分子模块解析, 参与, 中国科学院计划, 2013-08--2018-07
( 6 ) 鱼类特有的干扰素调节因子基因IRF11调控干扰素抗病毒反应 的作用机理, 负责人, 国家任务, 2016-01--2019-12
( 7 ) 鱼类TRIM16家族基因TRIM16a负调控干扰素抗病毒免疫反应的功能研究, 负责人, 国家任务, 2018-01--2021-12
( 8 ) 淡水鱼类抗病与抗逆性状形成的分子机理, 负责人, 国家任务, 2018-12--2022-12
( 9 ) 银鲫a亚类干扰素基因IFNa1转录成胞外和胞内干扰素两个转录本的选择性剪接机理及抗病毒机制, 负责人, 国家任务, 2020-01--2023-12
( 10 ) 淡水鱼类抗病性状形成及调控网络研究, 负责人, 国家任务, 2022-12--2027-12
( 11 ) 抗出血病基因的功能解析与新种质创制, 参与, 国家任务, 2023-09--2025-12
( 12 ) 大宗水产动物重大病毒病害致病机理与高效防控技术, 参与, 中国科学院计划, 2023-12--2027-12
( 2 ) 重要性状基因功能快速验证动物模型和技术平台的建立及其应用, 参与, 国家任务, 2010-01--2011-12
( 3 ) 不同斑马鱼干扰素基因的诱导表达及比较研究, 负责人, 国家任务, 2012-01--2012-12
( 4 ) 鱼类特有基因Gig1和Gig2在干扰素抗病毒反应中的功能研究, 负责人, 国家任务, 2013-01--2016-12
( 5 ) 鲤抗病分子模块解析, 参与, 中国科学院计划, 2013-08--2018-07
( 6 ) 鱼类特有的干扰素调节因子基因IRF11调控干扰素抗病毒反应 的作用机理, 负责人, 国家任务, 2016-01--2019-12
( 7 ) 鱼类TRIM16家族基因TRIM16a负调控干扰素抗病毒免疫反应的功能研究, 负责人, 国家任务, 2018-01--2021-12
( 8 ) 淡水鱼类抗病与抗逆性状形成的分子机理, 负责人, 国家任务, 2018-12--2022-12
( 9 ) 银鲫a亚类干扰素基因IFNa1转录成胞外和胞内干扰素两个转录本的选择性剪接机理及抗病毒机制, 负责人, 国家任务, 2020-01--2023-12
( 10 ) 淡水鱼类抗病性状形成及调控网络研究, 负责人, 国家任务, 2022-12--2027-12
( 11 ) 抗出血病基因的功能解析与新种质创制, 参与, 国家任务, 2023-09--2025-12
( 12 ) 大宗水产动物重大病毒病害致病机理与高效防控技术, 参与, 中国科学院计划, 2023-12--2027-12