基本信息
胡松年  男  博导  中国科学院微生物研究所
电子邮件: husn@im.ac.cn
通信地址: 北京市朝阳区北辰西路1号院3号
邮政编码: 100101

研究领域

   

招生信息

   
招生专业
071007-遗传学
0710J3-生物信息学
0710Z1-基因组学
招生方向
复杂基因组的精细结构解析
药物基因组学与精准用药指导
生物信息学工具开发与数据库构建

教育背景

1991-09--1996-07   中国农业大学   生物化学专业 获理学博士学位
1987-09--1991-07   天津商学院   食品工程专业 获理学学士学位
学历
   
学位
   

工作经历

   
工作简历
2019-08~现在, 中国科学院微生物研究所, 研究员 博士生导师
2003-02~2019-07,中国科学院北京基因组研究所, 研究员 博士生导师
2002-02~2008-09,浙江大学沃森基因组科学研究院, 教授 硕士生导师
1999-08~2003-02,中国科学院遗传与发育研究所人类基因组中心, 总工程师
1998-08~1999-07,美国西雅图华盛顿大学基因组中心, 访问学者
1996-09~1998-07,中国医学科学院基础医学研究所, 助理研究员
1991-09~1996-07,中国农业大学, 生物化学专业 获理学博士学位
1987-09~1991-07,天津商学院, 食品工程专业 获理学学士学位
社会兼职
   

教授课程

基因组信息系统与实践
基因组学分析技术与原理
基因组学技术与原理
基因组学
基因组学前沿
基因组学实用技术讲座

专利与奖励

   
奖励信息
(1) 河北省科学技术进步三等奖, 三等奖, 省级, 2015
(2) 唐山市科技进步二等奖, 二等奖, 市地级, 2015
(3) 国务院特殊津贴_, 国家级, 2014
(4) 中国科学院朱李月华优秀教师奖, , 院级, 2008
(5) 利用EST信息资源大规模克隆家蚕功能基因 浙江省科学技术一等奖, 一等奖, 省级, 2007
(6) 中国科学院优秀教师奖, , 院级, 2006
(7) 中国杂交水稻基因组计划 中国科学院杰出科技成就集体奖, , 院级, 2003
(8) 中国杂交水稻基因组计划 香港求是科技基金求是杰出科技成就集体奖, , 其他, 2002
专利成果
   

出版信息

   
发表论文
(1) REDO: RNA Editing Detection in Plant Organelles Based on Variant Calling Results, J Comput Biol., 2018, 第 11 作者
(2) Identification of a G2-like transcription factor, OsPHL3, functions as a negative regulator of flowering in rice by co-expression and reverse genetic analysis., BMC Plant Biol., 2018, 第 11 作者
(3) Tung Tree (Vernicia fordii, Hemsl.) Genome and Transcriptome Sequencing Reveals Co-Ordinate Up-Regulation of Fatty Acid β-Oxidation and Triacylglycerol Biosynthesis Pathways During Eleostearic Acid Accumulation in Seeds., Plant Cell Physiol., 2018, 第 11 作者
(4) Analysis of gut microbiota diversity and auxiliary diagnosis as a biomarker in patients with schizophrenia: A cross-sectional study., Schizophr Res., 2018, 第 11 作者
(5) Rice Expression Database (RED): An integrated RNA-Seq-derived gene expression database for rice, Journal of Genetics and Genomics, 2017, 第 12 作者
(6) Genetic Alterations in Esophageal Tissues From Squamous Dysplasia to Carcinoma, Gastroenterology, 2017, 第 12 作者
(7) DRDB: An Online Date Palm Genomic Resource Database, Front Plant Sci., 2017, 第 11 作者
(8) CYP2A6 Polymorphisms Associate with Outcomes of S-1 Plus Oxaliplatin Chemotherapy in Chinese Gastric Cancer Patients, Genomics, Proteomics & Bioinformatics, 2017, 第 11 作者
(9) ISVASE: identification of sequence variant associated with splicing event using RNA-seq data, BMC Bioinformatics, 2017, 第 11 作者
(10) A meta-analysis of the association of CKM gene rs8111989 polymorphism with sport performance, Biology of Sport, 2017, 第 11 作者
(11) REDO: RNA Editing Detection in Plant Organelles Based on Variant Calling Results, Journal of Computational Biology, 2017, 第 11 作者
(12) DRDB: An Online Date Palm Genomic Resource Database, Frontiers in Plant Science, 2017, 第 11 作者
(13) MVP: a microbe-phage interaction database, Nucleic Acids Research, 2017, 第 4 作者
(14) Comparative genome analysis of programmed DNA elimination in nematodes, Genome Research, 2017, 第 12 作者
(15) De novo Transcriptome Analysis Reveals Distinct Defense Mechanisms by Young and Mature Leaves of Hevea brasiliensis (Para Rubber Tree), Scientific Reports, 2016, 第 11 作者
(16) Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host, Nat Commun, 2016, 第 11 作者
(17) Conserved intramolecular interactions maintain myosin interacting-heads motifs explaining tarantula muscle super-relaxed state structural basis, Journal of molecular biology, 2016, 第 11 作者
(18) Information Commons for Rice (IC4R), Nucleic Acids Research, 2016, 第 11 作者
(19) Identification and analysis of house-keeping and tissue-specific genes based on RNA-seq data sets across 15 mouse tissues, Gene, 2016, 第 11 作者
(20) De novo sequencing and transcriptome analysis of Pleurotus eryngii subsp. tuoliensis (Bailinggu) mycelia in response to cold stimulation, Moleculars, 2016, 第 11 作者
(21) Evolview v2: an online visualization and management tool for customized and annotated phylogenetic trees, Nucleic Acids Research, 2016, 第 11 作者
(22) Identification and analysis of mouse non-coding RNA using transcriptome data, Science China. Life Sciences, 2016, 第 11 作者
(23) The rubber tree genome reveals new insights into rubber production and species adaptation, Nature Plants, 2016, 第 11 作者
(24) De novo sequencing and transcriptome analysis of Pleurotus eryngii subsp. tuoliensis (Bailinggu) mycelia in response to cold stimulation, Moleculars, 2016, 第 11 作者
(25) Metatranscriptomic analyses of plant cell wall polysaccharide degradation by microorganisms in cow rumen, Applied and Ennvironmental Microbiology, 2015, 第 11 作者
(26) Integrated analysis of gene expression and microRNA regulation in three leukemia-related lymphoblastic cell lines, Gene, 2015, 第 11 作者
(27) De novo transcriptome analysis of Medicago falcata reveals novel insights about the mechanisms underlying abiotic stress-responsive pathway, BMC Genomics, 2015, 第 11 作者
(28) Genome-wide mapping of 5-hydroxymethylcytosine in three rice cultivars reveals its preferential localization in transcriptionally silent transposable element genes, Journal of Experimental Botany, 2015, 第 11 作者
(29) An integrated RNA-Seq and network study reveals a complex regulation process of rice embryo during seed germination, Biochemical and Biophysical Research Communications, 2015, 第 11 作者
(30) Profiling microRNA expression during multi-staged date palm (Phoenix dactylifera L.) fruit development, Genomics, 2015, 第 11 作者
(31) Evaluation of the optimal dosage of S-1 in adjuvant SOX chemotherapy for gastric cancer, Oncology Letters, 2015, 第 11 作者
(32) Transcriptomic study of the red palm weevil Rhynchophorus ferrugineus embryogenesis, Insect Science, 2015, 第 11 作者
(33) Whole transcriptome RNA-seq analysis: tumorigenesis and metastasis of melanoma, Gene, 2014, 第 11 作者
(34) De novo characterization of the spleen transcriptome of the large yellow croaker (Pseudosciaena crocea) and analysis of the immune relevant genes and pathways involved in the antiviral response, PLoS One, 2014, 第 11 作者
(35) XELIRI compared with FOLFIRI as a second-line treatment in patients with metastatic colorectal cancer, Oncology Letters, 2014, 第 11 作者
(36) Transcriptional profiling of biomass degradation-related genes during Trichoderma reesei growth on different carbon sources, Journal of Biotechnology, 2014, 第 11 作者
(37) Transgenic rice plants overexpressing BBTI4 confer partial but broad-spectrum bacterial blight resistance, Journal of Plant Biology, 2013, 第 11 作者
(38) Dynamic transcriptomes of human myeloid leukemia cells, Genomics, 2013, 第 11 作者
(39) Genome sequence of the date palm Phoenix dactylifera L, Nat Commun., 2013, 第 1 作者
(40) The Complete Mitochondrial Genome of Gossypium hirsutum and Evolutionary Analysis of Higher Plant Mitochondrial Genomes, PLos One, 2013, 第 11 作者
(41) Insight into the specific virulence related genes and toxin-antitoxin virulent pathogenicity islands in swine streptococcosis pathogen Streptococcus equi ssp zooepidemicus strain ATCC35246, BMC Genomics, 2013, 第 11 作者
(42) Digital Gene Expression Tag Profiling Analysis of the Gene Expression Patterns Regulating the Early Stage of Mouse Spermatogenesis, PLoS One, 2013, 第 11 作者
(43) Large-scale collection and annotation of gene models for date palm (Phoenix dactylifera, L.), Plant Molecular Biology, 2012, 第 11 作者
(44) Comparative transcriptome analysis of transporters, phytohormone and lipid metabolism pathways in response to arsenic stress in rice (Oryza sativa L.) , New Phytologist , 2012, 第 11 作者
(45) High-throughput sequencing-based gene profiling on multi-staged fruit development of date palm (Phoenix dactylifera, L.), Plant Molecular Biology, 2012, 第 11 作者
(46) Evolutional and functional analysis of a serine protease in Spodoptera litura, Archives of Insect Biochemistry and Physiology, 2012, 第 11 作者
(47) Comparative analysis of the genomes of two field isolates of the rice blast fungus Magnaporthe oryzae, PLoS Genetics, 2012, 第 4 作者
(48) Pyrosequencing the Bemisia tabaci transcriptome reveals a highly diverse bacterial community and a robust system for insecticide resistance, PLoS One, 2012, 第 11 作者
(49) A large-scale gene discovery for the red palm weevil Rhynchophorus ferrugineus (Coleoptera: Curculionidae), Insect Science, 2012, 第 11 作者
(50) Thousands of novel transcripts identified in mouse cerebrum, testis, and ES cells based on ribo-minus RNA sequencing, Frontiers in Genetics, 2012, 第 11 作者
(51) Replication-associated mutational pressure (RMP) governs strand-biased compositional asymmetry (SCA) and gene organization in animal mitochondrial genomes, Current Genomics, 2012, 第 11 作者
(52) Complete genome sequence of the metabolically versatile halophilic archaeon Haloferax mediterranei, a Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) producer, Journal of Bacteriology, 2012, 第 11 作者
(53) Molecular identification of Diphyllobothrium latum and a brief review of diphyllobothriosis in China, Acta Parasitologica, 2012, 第 11 作者
(54) A complete sequence and transcriptomic analysis of date palm (Phoenix dactylifera L.) mitochondrial genome, PLoS One, 2012, 第 11 作者
(55) Transcriptome comparison between honey bee queen- and worker-destined larvae, Insect Biochemistry and Molecular Biology, 2012, 第 11 作者
(56) EvolView, an online tool for visualizing, annotating and managing phylogenetic trees, Nucleic Acids Research, 2012, 第 11 作者
(57) Genomic analysis of the multi-drug resistant Acinetobacter baumannii strain MDR-ZJ06 widely spread in China, Antimicrobial Agents and Chemotherapy. , 2011, 第 11 作者
(58) wapRNA: a web-based application for the processing of RNA sequences, Bioinformatics. , 2011, 第 11 作者
(59) Hydroxyurea-induced global transcriptional suppression in mouse ES cells, Carcinogenesis, 2010, 第 11 作者
(60) A comparison between ribo-minus RNA-sequencing and polyA-selected RNA-sequencing, Genomics, 2010, 第 11 作者
(61) Transcriptome and expression profiling analysis revealed changes of multiple signaling pathways involved in immunity in the large yellow croaker during Aeromonas hydrophila infection., BMC genomics, 2010, 第 11 作者
发表著作
( 1 ) 基因组数据分析手册, handbook of genomic data analysis, 浙江大学出版社, 2003-05, 第 1 作者
( 2 ) 基因表达序列标签(EST)数据, handbook of expressed sequence tag (est) data analysis, 浙江大学出版社, 2005-05, 第 1 作者
( 3 ) 基因组学概论(第二版), Introduction to Genomics (Second edition), 科学出版社, 2016-01, 第 2 作者
( 4 ) 转录组学与精准医学, Transcriptomics and Precision Medicine, 上海交通大学, 2017-12, 第 2 作者

科研活动

   
科研项目
( 1 ) 广东潮汕食管癌发病风险预测的分子基础研究, 参与, 省级, 2012-05--2015-12
( 2 ) 应用组学策略选育茶薪菇新品种与人工栽培技术研究, 主持, 部委级, 2012-01--2015-12
( 3 ) 基于第二代测序技术及比较转录组学的人参皂苷合成途径及调控网络研究, 主持, 国家级, 2012-01--2016-08
( 4 ) 水稻粒型分子模块系统解析, 主持, 部委级, 2013-08--2017-12
( 5 ) 2016YFC1202804, 主持, 国家级, 2016-07--2018-12
( 6 ) 精准医学大数据处理和利用的标准化技术体系建设, 参与, 国家级, 2016-07--2019-12
( 7 ) 转录组纵深信息挖掘, 主持, 国家级, 2006-12--2011-08
( 8 ) 基于小鼠多组织和细胞链特异性RNA-seq数据的Antisense RNA 分析及数据库构建, 主持, 国家级, 2013-01--2016-12
参与会议
   

合作情况

   
项目协作单位
   

指导学生