基本信息

张勇 男 硕导 中国科学院武汉病毒研究所
电子邮件: yzhang@wh.iov.cn
通信地址: 中国科学院武汉病毒研究所
邮政编码:
电子邮件: yzhang@wh.iov.cn
通信地址: 中国科学院武汉病毒研究所
邮政编码:
招生信息
招生专业
071005-微生物学
招生方向
病原微生物学
教育背景
2006-09--2009-06 中科院武汉病毒所 博士2001-09--2004-06 华中师范大学与中科院武汉病毒所联合培养 硕士1994-09--1998-06 华中师范大学 学士
工作经历
工作简历
2013-03~2014-06,洛克菲勒大学, 访问学者
教授课程
微生物前沿进展
专利与奖励
专利成果
( 1 ) 一种广谱抗植物病毒的转基因植物的制备方法, 发明, 2011, 第 2 作者, 专利号: 201110072905.6( 2 ) 一种广谱抗植物病毒的转基因植物的制备方法及应用 , 发明, 2012, 第 2 作者, 专利号: CN102492719A
出版信息
发表论文
[1] mBionull. 2024, [2] Wei Zhou, Shaojia Huang, Bridgette M Cumming, Yong Zhang, Wei Tang, Adrie J C Steyn, Shiyun Chen, Yangbo Hu. A Feedback Regulatory Loop Containing McdR and WhiB2 Controls Cell Division and DNA Repair in Mycobacteria. MBIO[J]. 2022, 13(2): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040748/.[3] Huang, Shaojia, Zhou, Wei, Tang, Wei, Zhang, Yong, Hu, Yangbo, Chen, Shiyun. Genome-scale analyses of transcriptional start sites in Mycobacterium marinum under normoxic and hypoxic conditions. BMC GENOMICS[J]. 2021, 22(1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022548/.[4] Yan, Yi, Wu, Ke, Chen, Jun, Liu, Haizhou, Huang, Yi, Zhang, Yong, Xiong, Jin, Quan, Weipeng, Wu, Xin, Liang, Yu, He, Kunlun, Jia, Zhilong, Wang, Depeng, Liu, Di, Wei, Hongping, Chen, Jianjun. Rapid Acquisition of High-Quality SARS-CoV-2 Genome via Amplicon-Oxford Nanopore Sequencing. VIROLOGICA SINICA[J]. 2021, 36(5): 901-912, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043101/.[5] Zhu, Yan, Mao, Chunyou, Ge, Xingyi, Wang, Zhongwei, Lu, Pei, Zhang, Yong, Chen, Shiyun, Hu, Yangbo. Characterization of a Minimal Type of Promoter Containing the-10 Element and a Guanine at the-14 or-13 Position in Mycobacteria. JOURNAL OF BACTERIOLOGY[J]. 2017, 199(21): http://www.corc.org.cn/handle/1471x/2373395.[6] Lu, Pei, Wang, Yifei, Zhang, Yong, Hu, Yangbo, Thompson, Karl M, Chen, Shiyun. RpoS-dependent sRNA RgsA regulates Fis and AcpP in Pseudomonas aeruginosa. MOLECULAR MICROBIOLOGY[J]. 2016, 102(2): 244-259, https://www.webofscience.com/wos/woscc/full-record/WOS:000386101000006.[7] Lu, Pei, Zhang, Yong, Hu, Yangbo, Francis, Matthew S, Chen, Shiyun. A cis-encoded sRNA controls the expression of fabH2 in Yersinia. FEBS LETTERS[J]. 2014, 588(10): 1961-1966, http://dx.doi.org/10.1016/j.febslet.2014.04.005.[8] Cai, Kun, Zhang, Yong, Yang, Baoyu, Chen, Shiyun. Yersinia enterocolitica ghost with msbB mutation provides protection and reduces proinflammatory cytokines in mice. VACCINE[J]. 2013, 31(2): 334-340, http://dx.doi.org/10.1016/j.vaccine.2012.11.004.[9] Lu, Pei, Zhang, Yong, Li, Lamei, Hu, Yangbo, Huang, Li, Li, Yunlong, Rayner, Simon, Chen, Shiyun. Small non-coding RNA SraG regulates the operon YPK_1206-1205 in Yersinia pseudotuberculosis. FEMS MICROBIOLOGY LETTERS[J]. 2012, 331(1): 37-43, https://www.webofscience.com/wos/woscc/full-record/WOS:000303438800006.[10] Hu, Yangbo, Feng, Lipeng, Li, Yunlong, Zhang, Yong, Lu, Pei, Rayner, Simon, Chen, Shiyun. Ribosomal Binding Site Switching: An Effective Strategy for High-Throughput Cloning Constructions. PLOS ONE[J]. 2012, 7(11): http://dx.doi.org/10.1371/journal.pone.0050142.[11] Hu, Chunyan, Xiong, Ning, Zhang, Yong, Rayner, Simon, Chen, Shiyun. Functional characterization of lipase in the pathogenesis of Staphylococcus aureus. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2012, 419(4): 617-620, https://www.webofscience.com/wos/woscc/full-record/WOS:000302335800004.[12] Zhang, Jingtao, Zhang, Yong, Du, Yuanyuan, Chen, Shiyun, Tang, Huiru. Dynamic Metabonomic Responses of Tobacco (Nicotiana tabacum) Plants to Salt Stress. JOURNAL OF PROTEOME RESEARCH[J]. 2011, 10(4): 1904-1914, http://dx.doi.org/10.1021/pr101140n.[13] Wang, Youru, Zhang, Yong, Yang, Baoyu, Chen, Shiyun. Characterization of SSU5C promoter of a rbcS gene from duckweed (Lemna gibba). MOLECULAR BIOLOGY REPORTS[J]. 2011, 38(4): 2563-2568, http://www.corc.org.cn/handle/1471x/2375886.[14] Pei, Shaobo, Zhang, Yong, Xu, Hao, Chen, Xinwen, Chen, Shiyun. Inhibition of the Replication of Hepatitis B Virus in Vitro by Pu-erh Tea Extracts. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2011, 59(18): 9927-9934, http://www.corc.org.cn/handle/1471x/2375939.[15] Hu, Yangbo, Lu, Pei, Zhang, Yong, Li, Yunlong, Li, Lamei, Huang, Li, Chen, Shiyun. Cra negatively regulates acid survival in Yersinia pseudotuberculosis. FEMS MICROBIOLOGY LETTERS[J]. 2011, 317(2): 190-195, http://www.corc.org.cn/handle/1471x/2376022.[16] Zhang, Yong, Hu, Yangbo, Yang, Baoyu, Ma, Fang, Lu, Pei, Li, Lamei, Wan, Chengsong, Rayner, Simon, Chen, Shiyun. Duckweed (Lemna minor) as a Model Plant System for the Study of Human Microbial Pathogenesis. PLOS ONE[J]. 2010, 5(10): http://www.corc.org.cn/handle/1471x/2375711.[17] Hu, Yangbo, Lu, Pei, Zhang, Yong, Li, Lamei, Chen, Shiyun. Characterization of an aspartate-dependent acid survival system in Yersinia pseudotuberculosis. FEBS LETTERS[J]. 2010, 584(11): 2311-2314, http://dx.doi.org/10.1016/j.febslet.2010.03.045.[18] Pei, Shaobo, Xiong, Ning, Zhang, Yong, Chen, Shiyun. Increasing M2 epitope density enhances systemic and mucosal immune responses to influenza A virus. BIOTECHNOLOGY LETTERS[J]. 2009, 31(12): 1851-1856, http://www.corc.org.cn/handle/1471x/2375543.[19] Ma, Fang, Wang, Yao, Zhang, Yong, Xiong, Ning, Yang, Baoyu, Chen, Shiyun. Heterologous expression of human paraoxonases in Pseudomonas aeruginosa inhibits biofilm formation and decreases antibiotic resistance. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2009, 83(1): 135-141, http://www.corc.org.cn/handle/1471x/2375556.[20] Xiong, Ning, Hu, Chunyan, Zhang, Yong, Chen, Shiyun. Interaction of sortase A and lipase 2 in the inhibition of Staphylococcus aureus biofilm formation. ARCHIVES OF MICROBIOLOGY[J]. 2009, 191(12): 879-884, http://www.corc.org.cn/handle/1471x/2375625.[21] Wang, Zhihua, Song, Jianhua, Zhang, Yong, Yang, Baoyu, Chen, Shiyun. Expression of baculovirus anti-apoptotic p35 gene in tobacco enhances tolerance to abiotic stress. BIOTECHNOLOGY LETTERS[J]. 2009, 31(4): 585-589, http://www.corc.org.cn/handle/1471x/2375569.[22] Zhang, Yong, Ma, Fang, Wang, Yao, Yang, Baoyu, Chen, Shiyun. Expression of v-cath gene from HearNPV in tobacco confers an antifeedant effect against Helicoverpa armigera. JOURNAL OF BIOTECHNOLOGY[J]. 2008, 138(1-2): 52-55, http://www.corc.org.cn/handle/1471x/2375472.[23] Zhang, Yong, Zhao, Lihong, Wang, Yao, Yang, Baoyu, Chen, Shiyun. Enhancement of heavy metal accumulation by tissue specific co-expression of iaaM and ACC deaminase genes in plants. CHEMOSPHERE[J]. 2008, 72(4): 564-571, http://dx.doi.org/10.1016/j.chemosphere.2008.03.043.[24] Ning XIONG, Yong ZHANG, Yao WANG, Baoyu YANG, Shiyun CHEN. Isolation and Identification of Canine Parvovirus Serotype 2a and Its VP2 Protein Expression in Transgenic Tobacco. 中国病毒学:英文版[J]. 2008, 23(3): 203-210, http://lib.cqvip.com/Qikan/Article/Detail?id=27498513.[25] Wang Yao, Dai Yue, Zhang Yong, Hu YangBo, Yang BaoYu, Chen ShiYun. Effects of quorum sensing autoinducer degradation gene on virulence and biofilm formation of Pseudomonas aeruginosa. SCIENCE IN CHINA SERIES C-LIFE SCIENCES[J]. 2007, 50(3): 385-391, http://www.corc.org.cn/handle/1471x/2375421.[26] Zhang Yong, Yang Baoyu, Chen Shiyun. Inheritance Analysis of Herbicide-Resistant Transgenic Soybean Lines. ACTA GENETICA SINICA[J]. 2006, 33(12): 1105-1111, http://dx.doi.org/10.1016/S0379-4172(06)60148-0.
科研活动
科研项目
( 1 ) 非编码RNA MicF调控假结核耶尔森氏菌耐酸机理研究, 主持, 国家级, 2012-01--2014-12( 2 ) LcrQ调控假结核耶尔森氏菌的机制, 参与, 国家级, 2015-12--2019-12( 3 ) 针对CpxR信号的抗菌药物治疗, 参与, 市地级, 2015-12--2019-12( 4 ) 噬菌体NM1的Gp29通过NadE参与控制金黄色葡萄球菌的机制研究, 主持, 国家级, 2017-01--2020-12
指导学生
已指导学生
唐丽 硕士研究生 085238-生物工程
现指导学生
袁莉莎 硕士研究生 100102-免疫学