基本信息

吕军鸿  男  博导  中国科学院上海应用物理研究所、中国科学院上海高等研究院
电子邮件: lvjh@@sari.ac.cn
通信地址: 上海市浦东新区海科路100号
邮政编码: 201800

研究领域

1. 生物膜界面物理化学:膜-蛋白质相互作用、靶向细胞膜药物

2. 生物医学光谱学:红外/太赫兹光谱、单细胞成像

3. 纳米生物学: 气体生物效应、抗菌纳米材料

招生信息

   
招生专业
071011-生物物理学
070301-无机化学
070202-粒子物理与原子核物理
招生方向
纳米科学和单分子生物物理
纳米材料和纳米生物学
生物光子学

教育背景

2001-03--2004-06   中国科学院上海应用物理研究所   博士

专利与奖励

   
奖励信息
(1) 中国科学院“****”, , 院级, 2013
(2) 上海市浦江人才, , 省级, 2013
(3) 欧盟居里学者, , 其他, 2011
(4) 美国血液学会Travel Award, , 专项, 2009
(5) 上海市科技进步奖, 三等奖, 省级, 2007
(6) 上海—联合利华研究与发展基金奖学金, , 专项, 2004
专利成果
( 1 ) 一种基于纳米力学的蛋白分析方法, 专利授权, 2021, 第 1 作者, 专利号: CN109489545B

( 2 ) 含磷脂的微乳液及制备方法、在研究界面水性能中的应用, 发明专利, 2016, 第 2 作者, 专利号: CN106198444A

( 3 ) 分离与纯化单个病毒的方法, 发明专利, 2009, 第 1 作者, 专利号: CN101565691

( 4 ) 用于AFM研究的病毒样品的制备方法及制得的病毒样品, 发明专利, 2008, 第 5 作者, 专利号: CN101109675

( 5 ) DNA单分子有序化测序方法, null, 2006, 第 3 作者, 专利号: CN1266283

( 6 ) 单个生物分子分离装置, null, 2006, 第 1 作者, 专利号: CN2785098

( 7 ) 单个生物大分子的分离方法, null, 2006, 第 1 作者, 专利号: CN1238370

( 8 ) 快速制备AFM生物样品的方法, 发明专利, 2005, 第 2 作者, 专利号: CN1677075

( 9 ) 一种基于原子力显微镜的测量衬底上样品高度的装置, null, 2004, 第 7 作者, 专利号: CN2600809

出版信息

   
发表论文
[1] Zhang, Guangxu, Wang, Yadi, Qian, Jiang, Wang, Yue, Li, Xueling, Lue, Junhong. Terahertz refractive phenotype of living cells. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY[J]. 2023, 10: http://dx.doi.org/10.3389/fbioe.2022.1105249.
[2] Wang, Cheng, Cheng, Tingting, Lu, Qianqian, Li, Wenzhen, Liu, Ben, Yue, Lijun, Du, Maoru, Sheng, Wenxue, Lu, Zhaochen, Yang, Jingnan, Geng, Feng, Gao, Xue, Lu, Junhong, Pan, Xiaohong. Oxygen therapy accelerates apoptosis induced by selenium compounds via regulating Nrf2/MAPK signaling pathway in hepatocellular carcinoma. PHARMACOLOGICAL RESEARCH[J]. 2023, 187: http://dx.doi.org/10.1016/j.phrs.2022.106624.
[3] 吕军鸿. Nanobubble can modulate microbial communities and sedimentary ecosystem during the treatment of pond water. Environ. Sci.: Water Res. Technol.[J]. 2023, [4] 郑晋, 吕军鸿, 胡钧. An antioxidation strategy based on ultra-small nanobubbles without exogenous antioxidants. Sci Rep[J]. 2023, [5] Yujie Chen, Ruimin Xu, Shuang Zhou, Chengchen Zhao, Ziyue Hu, Yuwei Hua, Yanhong Xiong, Xiaoyu Liu, Junhong L, Yao Sun, Chong Li, Shaorong Gao, Yong Zhang. Mechanical strain treatment improves nuclear transfer reprogramming efficiency by enhancing chromatin accessibility. STEM CELL REPORTS. 2023, 18(4): 807-816, http://dx.doi.org/10.1016/j.stemcr.2023.02.007.
[6] 吕军鸿. Label-free analysis of biofilm phenotypes by infrared micro- and correlation- spectroscopy. Anal Bioanal Chem[J]. 2023, [7] Yuru Cao, Ben Liu, Wenzhen Li, Feng Geng, Xue Gao, Lijun Yue, Huiping Liu, Congying Liu, Zhenguo Su, Junhong L, Xiaohong Pan. Protopanaxadiol manipulates gut microbiota to promote bone marrow hematopoiesis and enhance immunity in cyclophosphamide‐induced immunosuppression mice. MEDCOMM[J]. 2023, 4(2): n/a-n/a, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950037/.
[8] 吕军鸿. Hydrogel microenvironment contributes to chemical-induced differentiation of Mesenchymal stem cells: Single cell infrared microspectroscopy characterization. Anal Bioanal Chem[J]. 2023, [9] Wang, Yadi, Liu, Huiping, Geng, Feng, Yang, Pan, Lu, Junhong, Li, Xueling. Label-free analysis of biofilm phenotypes by infrared micro- and correlation spectroscopy. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2023, 415(17): 3515-3523, http://dx.doi.org/10.1007/s00216-023-04741-4.
[10] Wang, Yadi, Zheng, Jin, Cheng, Jie, Zhou, Runlong, Li, Xueling, Hu, Jun, Lue, Junhong. Nanobubbles can modulate microbial communities and sedimentary ecosystem during the treatment of pond water. ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY[J]. 2023, 9(7): 1804-1812, http://dx.doi.org/10.1039/d3ew00257h.
[11] Jiao, Shi, Li, Chuanchuan, Guo, Fenghua, Zhang, Jinjin, Zhang, Hui, Cao, Zhifa, Wang, Wenjia, Bu, Wenbo, Lin, Mobin, Lue, Junhong, Zhou, Zhaocai. SUN1/2 controls macrophage polarization via modulating nuclear size and stiffness. NATURE COMMUNICATIONS[J]. 2023, 14(1): http://dx.doi.org/10.1038/s41467-023-42187-5.
[12] Yadi Wang, Yu Gao, Xueling Li, Geng Tian, Junhong L. Single-cell infrared phenomics identifies cell heterogeneity of individual pancreatic islets in mouse model. ANALYTICA CHIMICA ACTA[J]. 2023, 1258: http://dx.doi.org/10.1016/j.aca.2023.341185.
[13] Qian, Jiang, Wang, Yadi, Li, Xueling, Lu, Junhong. Hydrogel microenvironment contributes to chemical-induced differentiation of mesenchymal stem cells: single-cell infrared microspectroscopy characterization. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2023, 415(17): 3305-3312, http://dx.doi.org/10.1007/s00216-023-04746-z.
[14] Tingting Cheng, Cheng Wang, Qianqian Lu, Yuru Cao, Weiwei Yu, Xue Gao, 吕军鸿, Xiaohong Pan. Metformin inhibits the tumor-promoting effect of low-dose resveratrol, and enhances the anti-tumor activity of high-dose resveratrol by increasing its reducibility in triple negative breast cancer. Free Radical Biology & Medicine[J]. 2022, [15] Tang, Chao, Wang, Yadi, Cheng, Jie, Chang, Chao, Hu, Jun, Lu, Junhong. Probing terahertz dynamics of multidomain protein in cell-like confinement. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY[J]. 2022, 275: http://dx.doi.org/10.1016/j.saa.2022.121173.
[16] 郑晋, 王亚迪, 周润龙, 李雪玲, 吕军鸿, 胡钧. 微纳米气泡对池塘微生态系统的调节作用. 净水技术. 2022, 41(8): 123-128, http://lib.cqvip.com/Qikan/Article/Detail?id=7107950360.
[17] Zhang, Guangxu, Tang, Chao, Pan, Lexin, Lu, Junhong. Low-frequency collective motion of DNA-binding domain defines p53 function. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS[J]. 2022, 90(3): 881-888, [18] Feng Geng, Zhang GuangXu, YaDi Wang, 吕军鸿. Membrane phosphatidylserine allosterically regulates the cytosolic phospholipase A2 activity via an electrostatic-switch mechanism. Soft Matter[J]. 2022, [19] Qian, Jiang, Gao, Xue, Wang, YaDi, Li, XueLing, Hu, Jun, Lu, JunHong. Synchrotron Infrared Microspectroscopy for Stem Cell Research. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESnull. 2022, 23(17): http://dx.doi.org/10.3390/ijms23179878.
[20] 吕军鸿. 砷(III)对p53突变蛋白活性恢复作用的太赫兹物理机制. 物理学报. 2021, [21] 唐朝, 张广旭, 胡钧, 吕军鸿. 砷(Ⅲ)对p53突变蛋白活性恢复作用的太赫兹物理机制. 物理学报[J]. 2021, 70(12): 133-140, http://lib.cqvip.com/Qikan/Article/Detail?id=7104924845.
[22] Jinfang LU, Jin ZHENG, Yadi WANG, Jie CHENG, Xueling LI, Jun HU, Bin LI, Junhong L. Response of Escherichia coli to hydrogen nanobubbles: an in vitro evaluation using synchrotron infrared spectroscopy. JOURNAL OF ZHEJIANG UNIVERSITY. SCIENCE. B[J]. 2021, 22(11): 966-970, [23] Zhang, Guangxu, Tang, Chao, Pan, Lexin, Lu, Junhong, 吕军鸿. Low-frequency collective motion of DNA-binding domain defines p53 function. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS[J]. 2021, [24] Mingyu Wu, Yu Sun, Meiru Zhu, Laiyu Zhu, Junhong Lu, Feng Geng, 吕军鸿. Molecular Dynamics-Based Allosteric Prediction Method to Design Key Residues in Threonine Dehydrogenase for Amino-Acid Production. ACS OMEGA[J]. 2021, 6(16): 10975-10983, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153896/.
[25] Tang, Chao, Yang, Jing, Wang, Yadi, Cheng, Jie, Li, Xueling, Chang, Chao, Hu, Jun, Lu, Junhong. Integrating terahertz metamaterial and water nanodroplets for ultrasensitive detection of amyloid beta aggregates in liquids. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2021, 329: http://dx.doi.org/10.1016/j.snb.2020.129113.
[26] Wang, Yadi, Dai, Wentao, Liu, Zhixiao, Liu, Jixiang, Cheng, Jie, Li, Yuanyuan, Li, Xueling, Hu, Jun, Lu, Junhong. Single-Cell Infrared Microspectroscopy Quantifies Dynamic Heterogeneity of Mesenchymal Stem Cells during Adipogenic Differentiation. ANALYTICAL CHEMISTRY[J]. 2021, 93(2): 671-676, https://www.webofscience.com/wos/woscc/full-record/WOS:000612336200003.
[27] 吕军鸿. Integrating terahertz metamaterial with water nanodroplets for ultrasensitive detection of soluble amyloid b aggregates in liquids. Sensors & Actuators: B. Chemical. 2021, [28] Tang Chao, Zhang GuangXu, Hu Jun, Lu JunHong, 吕军鸿. Terahertz physical mechanism of arsenic (III) restoring p53 mutant protein activity. ACTA PHYSICA SINICA[J]. 2021, 70(12): [29] Wang, Yadi, Dai, Wentao, Wang, Yue, Liu, Jixiang, Liu, Zhixiao, Li, Yuanyuan, Li, Xueling, Hu, Jun, Lu, Junhong. How many cells are enough for single-cell infrared spectroscopy?. CHEMICAL COMMUNICATIONS[J]. 2020, 56(26): 3773-3776, https://www.webofscience.com/wos/woscc/full-record/WOS:000526690200013.
[30] Wang, Yadi, Wang, Yue, Qian, Jiang, Pan, Xiaohong, Li, Xueling, Chen, Feng, Hu, Jun, Lu, Junhong. Single-cell infrared phenomics: phenotypic screening with infrared microspectroscopy. CHEMICAL COMMUNICATIONS[J]. 2020, 56(86): 13237-13240, http://dx.doi.org/10.1039/d0cc05721e.
[31] Cheng, Jie, Tang, Chao, Li, Xueling, Hu, Jun, Lu, Junhong. Hydrogen molecules can modulate enzymatic activity and structural properties of pepsin in vitro. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2020, 189: http://dx.doi.org/10.1016/j.colsurfb.2020.110856.
[32] Jinjin Zhang, Yizhou Yang, Shuo Yang, Jie Song, Ying Wang, Xiaoguo Liu, Qingqing Yang, Yue Shen, Shuo Wang, Haijun Yang, Junhong L, Bin Li, Haiping Fang, Ratnesh Lal, Daniel M Czajkowsky, Jun Hu, Guosheng Shi, Yi Zhang. Unconventional Atomic Structure of Graphene Sheets on Solid Substrates. Small[J]. 2019, 15(42): https://www.doi.org/10.1002/smll.201902637.
[33] Yang, Jing, Tang, Chao, Wang, Yadi, Chang, Chao, Zhang, Jianbing, Hu, Jun, Lu, Junhong. The terahertz dynamics interfaces to ion-lipid interaction confined in phospholipid reverse micelles. CHEMICAL COMMUNICATIONS[J]. 2019, 55(100): 15141-15144, https://www.webofscience.com/wos/woscc/full-record/WOS:000502728800026.
[34] Wang, YaDi, Li, XueLing, Hu, Jun, Lu, JunHong. Synchrotron infrared spectral regions as signatures for foodborne bacterial typing. NUCLEAR SCIENCE AND TECHNIQUES[J]. 2019, 30(2): 25-, http://lib.cqvip.com/Qikan/Article/Detail?id=7001554659.
[35] Song, Dingka, Meng, Junchen, Cheng, Jie, Fan, Zheng, Chen, Pengyu, Ruan, Hefei, Tu, Zhongyuan, Kang, Ning, Li, Nan, Xu, Ying, Wang, Xiaobo, Shi, Fei, Mu, Libing, Li, Tengfei, Ren, Wenran, Lin, Xin, Zhu, Jun, Fang, Xiaohong, Amrein, Matthias W, Wu, Weihui, Yan, LiTang, Lu, Junhong, Xia, Tie, Shi, Yan, 吕军鸿. Pseudomonas aeruginosa quorum-sensing metabolite induces host immune cell death through cell surface lipid domain dissolution. NATURE MICROBIOLOGY[J]. 2019, 4(1): 97-+, [36] Wang, Y, Wang, YD, Huang, LN, Liu, XY, Hu, J, L, JH. Evaluating the biochemical changes of LPS-stimulated endothelial cells by synchrotron FTIR microspectroscopy at a single-cell level. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2019, 411(27): 7157-7164, http://dx.doi.org/10.1007/s00216-019-02083-8.
[37] Liu, Wenjing, Guo, Yourong, Wang, Kaizhe, Zhou, Xingfei, Wang, Ying, Lu, Junhong, Shao, Zhifeng, Hu, Jun, Czajkowsky, Daniel M, Li, Bin. Atomic force microscopy-based single-molecule force spectroscopy detects DNA base mismatches. NANOSCALE[J]. 2019, 11(37): 17206-17210, [38] Cheng, Jie, Wang, Yadi, Pan, Yatao, Li, Xueling, Hu, Jun, Lu, Junhong. Single-molecule nanomechanical spectroscopy shows calcium ions contribute to chain association and structural flexibility of blood clotting factor VIII. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2019, 513(4): 857-861, http://dx.doi.org/10.1016/j.bbrc.2019.04.068.
[39] Cheng, Jie, Geng, Feng, Hu, Jun, Lu, Junhong. Single-molecule measurement and bioinformatics analysis suggest a preferred orientation of human coagulation factor VIII on hydrophobic interfaces. BIOPHYSICAL CHEMISTRY[J]. 2019, 248: 9-15, http://dx.doi.org/10.1016/j.bpc.2019.03.001.
[40] YaDi Wang, XueLing Li, Jun Hu, JunHong Lu, 吕军鸿. Synchrotron infrared spectral regions as signatures for foodborne bacterial typing. 核技术:英文版[J]. 2019, 30(2): 109-113, http://lib.cqvip.com/Qikan/Article/Detail?id=7001554659.
[41] 吕军鸿. AFM单分子力谱技术在G四链体研究中的应用. 南方医科大学学报. 2018, [42] Huang, Lina, Zhang, Xiaohua, Ma, Xiaohong, Zhang, Dong, Li, Dongxiao, Feng, Jiali, Pan, Xinjie, Lu, Junhong, Wang, Xiaozhi, Liu, Xiangyong. Berberine alleviates endothelial glycocalyx degradation and promotes glycocalyx restoration in LPS-induced ARDS. INTERNATIONAL IMMUNOPHARMACOLOGY[J]. 2018, 65: 96-107, http://dx.doi.org/10.1016/j.intimp.2018.10.001.
[43] Xiankai Jiang, Jinjin Zhang, Bo Zhou, Pei Li, Xiaojuan Hu, Zhi Zhu, Yanwen Tan, Chao Chang, Junhong L, Bo Song, 吕军鸿. Anomalous behavior of membrane fluidity caused by copper-copper bond coupled phospholipids. SCIENTIFIC REPORTS[J]. 2018, 8(1): https://doaj.org/article/0e9900c342eb4c9c838c199ccb99afbb.
[44] Liu, XiangYong, Xu, HaiXiao, Li, JianKui, Zhang, Dong, Ma, XiaoHong, Huang, LiNa, Lu, JunHong, Wang, XiaoZhi. Neferine Protects Endothelial Glycocalyx via Mitochondrial ROS in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome. FRONTIERS IN PHYSIOLOGY[J]. 2018, 9: https://doaj.org/article/8eb6c173530c46f88f9374da7b5b7529.
[45] 潘亚涛, 吕军鸿. 基于太赫兹光谱技术的生物膜界面水研究. 激光与光电子学进展[J]. 2017, 54(4): "315-320", http://www.corc.org.cn/handle/1471x/2224586.
[46] 刘知晓, 张金金, 王鑫艳, 陈峰. 利用原子力显微镜峰值力定量测量模式分析人间充质干细胞早期分化的力学表型. 第二军医大学学报[J]. 2017, 38(10): 1261-1266, http://lib.cqvip.com/Qikan/Article/Detail?id=7000398501.
[47] Zhang, Lijuan, Zhang, Yuebin, Cheng, Jie, Wang, Lei, Wang, Xingya, Zhang, Meng, Gao, Yi, Hu, Jun, Zhang, Xuehua, Lu, Junhong, Li, Guohui, Tai, Renzhong, Fang, Haiping, 吕军鸿. Inert Gas Deactivates Protein Activity by Aggregation. SCIENTIFIC REPORTS[J]. 2017, 7(1): http://cas-ir.dicp.ac.cn/handle/321008/149979.
[48] Ya-Di Wang, Xue-Ling Li, Zhi-Xiao Liu, Xing-Xing Zhang, Jun Hu, Jun-Hong Lu, 吕军鸿. Discrimination of foodborne pathogenic bacteria using synchrotron FTIR microspectroscopy. 核技术:英文版[J]. 2017, 28(4): 38-43, http://lib.cqvip.com/Qikan/Article/Detail?id=7000198280.
[49] Hu, XiaoJuan, Liu, ZhiXiao, Wang, YaDi, Li, XueLing, Hu, Jun, Lu, JunHong. Synchrotron FTIR spectroscopy reveals molecular changes in Escherichia coli upon Cu2+ exposure. NUCLEAR SCIENCE AND TECHNIQUES[J]. 2016, 27(3): http://ir.sinap.ac.cn/handle/331007/26643.
[50] Wang, Shuo, Wang, Xingya, Zhao, Binyu, Wang, Lei, Qiu, Jie, Zhou, Limin, Dong, Yaming, Li, Bin, Lu, Junhong, Wang, Ying, Zhang, Yi, Zhang, Lijuan, Hu, Jun, 吕军鸿. Size-Dependent Stiffness of Nanodroplets: A Quantitative Analysis of the Interaction between an AFM Probe and Nanodroplets. LANGMUIR[J]. 2016, 32(43): 11230-11235, http://ir.sinap.ac.cn/handle/331007/26625.
[51] Liu, Zhixiao, Tang, Yuzhao, Chen, Feng, Liu, Xia, Liu, Zhaojian, Zhong, Jiajia, Hu, Jun, Lu, Junhong, 吕军鸿. Synchrotron FTIR microspectroscopy reveals early adipogenic differentiation of human mesenchymal stem cells at single-cell level. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2016, 478(3): 1286-1291, [52] Yadi Wang, Jun Hu, Qilong Xu, Xingxing Zhang, Xueling Li, Junhong L. Multi-metal element analysis for the identification of foodborne pathogenic bacteria. ROYAL SOCIETY OF CHEMISTRY. 2016, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201912010194047ZK.
[53] Zhang, Xingxing, Li, Xueling, Wang, Yadi, Xu, Qilong, Hu, Jun, Lu, Junhong, 吕军鸿. Multi-metal element analysis for the identification of foodborne pathogenic bacteria. ANALYTICAL METHODS[J]. 2016, 8(27): 5421-5426, http://ir.sinap.ac.cn/handle/331007/26580.
[54] Zhao, Binyu, Wang, Xingya, Song, Yang, Hu, Jun, Lu, Junhong, Zhou, Xingfei, Tai, Renzhong, Zhang, Xuehua, Zhang, Lijuan, 吕军鸿. Stiffness and evolution of interfacial micropancakes revealed by AFM quantitative nanomechanical imaging. PHYSICAL CHEMISTRY CHEMICAL PHYSICS[J]. 2015, 17(20): 13598-13605, http://ir.sinap.ac.cn/handle/331007/24579.
[55] Song, Yang, Zhao, Binyu, Zhang, Lijuan, Lu, Junhong, Wang, Shuo, Dong, Yaming, Hu, Jun, 吕军鸿. The Origin of the "Snap-In" in the Force Curve between AFM Probe and the Water/Gas Interface of Nanobubbles. CHEMPHYSCHEM[J]. 2014, 15(3): 492-499, https://www.webofscience.com/wos/woscc/full-record/WOS:000331407900011.
[56] Lu, Junhong, Yang, Ju, Dong, Mingdong, Sahin, Ozgur, 吕军鸿. Nanomechanical spectroscopy of synthetic and biological membranes. NANOSCALE[J]. 2014, 6(13): 7604-7608, https://www.webofscience.com/wos/woscc/full-record/WOS:000337786700063.
[57] 吕军鸿. Direct Resolution of the Pitch of DNA on Positively Charged Lipid Bilayers by Frequency-Modulation AFM. J. Shanghai Jiaotong Univ. (Sci.). 2014, [58] 陈润生. Gold nanoparticle-assisted primer walking for closing the human chromosomal gap. ANALYTICAL METHODS[J]. 2013, 5(40): 4746-4749, [59] Zhao, Binyu, Song, Yang, Wang, Shuo, Dai, Bin, Zhang, Lijuan, Dong, Yaming, Lu, Junhong, Hu, Jun, 吕军鸿. Mechanical mapping of nanobubbles by PeakForce atomic force microscopy. SOFT MATTER[J]. 2013, 9(37): 8837-8843, https://www.webofscience.com/wos/woscc/full-record/WOS:000323844600006.
[60] Junhong Lu PhD, Gary E Gilbert MD. Focal Procoagulant Activity in Space Between TNF-α Treated Endothelial Cells Mediates Focal Fibrin Accumulation and Anti-Streptococcal Function. BLOOD[J]. 2012, 120(21): 3307-3307, [61] Valerie A Novakovic MS, Junhong Lu PhD, Gary E Gilbert MD. Antibody ESH4, Against the Factor VIII C2 Domain, Causes a Remote Change near the Factor IXa Active Site and Inhibition That Is Related to Membrane Composition. BLOOD[J]. 2012, 120(21): 3355-3355, [62] Lue, Junhong, Pipe, Steven W, Miao, Hongzhi, Jacquemin, Marc, Gilbert, Gary E, 吕军鸿. A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain for cofactor function. BLOOD[J]. 2011, 117(11): 3181-3189, http://dx.doi.org/10.1182/blood-2010-08-301663.
[63] 吕军鸿. A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain epitopes for cofactor function. 2011, [64] Lue, Junhong, Ye, Ming, Duan, Na, Li, Bin, 吕军鸿. Enzymatic Digestion of Single DNA Molecules Anchored on Nanogold-Modified Surfaces. NANOSCALE RESEARCH LETTERS[J]. 2009, 4(9): 1029-1034, http://www.irgrid.ac.cn/handle/1471x/393261.
[65] 王鹏, 杨海军, 王化斌, 李海, 王鑫艳, 汪颖, 吕军鸿, 李宾, 张益, 胡钧. Modification of AFM Tips for Facilitating Picking-up of Nanoparticles. 中国物理快报:英文版[J]. 2008, 25(7): 2407-2409, http://lib.cqvip.com/Qikan/Article/Detail?id=27686135.
[66] 王鹏, 吕军鸿, 王鑫艳, 杨海军, 王化斌, 黄一波, 李宾. 戊二醛交联固定病毒颗粒及其在衬底表面上分散的研究. 核技术[J]. 2008, 31(7): 557-560, http://lib.cqvip.com/Qikan/Article/Detail?id=27740494.
[67] Wang, Peng, Wang, Xinyan, Yang, Haijun, Lue, Junhong, 吕军鸿. DISPERSION AND FIXATION OF ADENO-ASSOCIATED VIRUS WITH GLUTARALDEHYDE FOR AFM STUDIES. SURFACE REVIEW AND LETTERS[J]. 2008, 15(5): 595-598, http://www.irgrid.ac.cn/handle/1471x/394001.
[68] Wang Peng, Yang HaiJun, Wang HuaBin, Li Hai, Wang XinYan, Wang Ying, Lue JunHong, Li Bin, Zhang Yi, Hu Jun, 吕军鸿. Modification of AFM tips for facilitating picking-up of nanoparticles. CHINESE PHYSICS LETTERS[J]. 2008, 25(7): 2407-2409, http://lib.cqvip.com/Qikan/Article/Detail?id=27686135.
[69] 吕鸣, 李雪玲, 吕军鸿, 邵志峰, 胡钧. 基于纳米操纵的基因组测序技术与策略. 电子显微学报[J]. 2007, 26(5): 488-493, http://lib.cqvip.com/Qikan/Article/Detail?id=25571853.
[70] 汪颖, 张益, 李宾, 吕军鸿, 黄一波, 胡钧. 基于“纳米蘸笔技术”的单个纳米颗粒在不同基底表面的转移. 电子显微学报[J]. 2007, 26(5): 484-487, http://lib.cqvip.com/Qikan/Article/Detail?id=25571852.
[71] Wang, Peng, Li, Hai, Yang, Hai Jun, Wang, Hua Bing, Lu, Jun Hong, Zhang, Yi, Hu, Jun. Glycerol facilitates the disaggregation of recombinant adeno-associated virus serotype 2 on mica surface. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2007, 60(2): 264-267, http://dx.doi.org/10.1016/j.colsurfb.2007.06.027.
[72] An, Hongjie, Huang, Jiehuan, Lue, Ming, Li, Xueling, Lue, Junhong, Li, Haikuo, Zhang, Yi, Li, Minqian, Hu, Jun. Single-base resolution and long-coverage sequencing based on single-molecule nanomanipulation. NANOTECHNOLOGY[J]. 2007, 18(22): http://www.irgrid.ac.cn/handle/1471x/397617.
[73] Li, Bin, Zhang, Yi, Yan, Shuhua, Lu, JunHong, Ye, Ming, Li, Minqian, Hu, Jun, 吕军鸿. Positioning scission of single DNA molecules with nonspecific endonuclease based on nanomanipulation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2007, 129(21): 6668-+, http://www.irgrid.ac.cn/handle/1471x/397589.
[74] Zhang, Yi, Lu, Junhong, Li, Minqian, Hu, Jun. A strategy for ordered single molecule sequencing based on nanomanipulation (OsmSN). INTERNATIONAL JOURNAL OF NANOTECHNOLOGY[J]. 2007, 4(1-2): 163-170, http://www.irgrid.ac.cn/handle/1471x/397673.
[75] Wang, Ying, Zhang, Yi, Li, Bin, Lu, Junhong, Hu, Jun. Capturing and depositing one nanoobject at a time: Single particle dip-pen nanolithography. APPLIED PHYSICS LETTERS[J]. 2007, 90(13): http://www.irgrid.ac.cn/handle/1471x/397683.
[76] Lu, Junhong, An, Hongjie, Li, Haikuo, Li, Xueling, Wang, Ying, Li, Minqian, Zhang, Yi, Hu, Jun. Nanodissection, isolation, and PCR amplification of single DNA molecules. SURFACE AND INTERFACE ANALYSIS[J]. 2006, 38(6): 1010-1013, https://www.webofscience.com/wos/woscc/full-record/WOS:000238329400005.
[77] Lu JunHong, Li HaiKuo, An HongJie, Wang GuoHua, Wang Ying, Li MinQian, Zhang Yi, Li Bin, Hu Jun, IEEE, 吕军鸿. Nano-manipulation of single DNA molecules based on atomic force microscopy. 2005 27TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-7[J]. 2005, 7478-7481, http://www.irgrid.ac.cn/handle/1471x/451998.
[78] Li, HK, Huang, JH, Lv, JH, An, HJ, Zhang, XD, Zhang, ZZ, Fan, CH, Hu, J. Nanoparticle PCR: Nanogold-assisted PCR with enhanced specificity. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2005, 44(32): 5100-5103, http://www.irgrid.ac.cn/handle/1471x/397544.
[79] Lu, JH, Li, HK, An, HJ, Wang, GH, Wang, Y, Li, MQ, Zhang, Y, Hu, J. Positioning isolation and biochemical analysis of single DNA molecules based on nanomanipulation and single-molecule PCR. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2004, 126(36): 11136-11137, https://www.webofscience.com/wos/woscc/full-record/WOS:000223799900011.
[80] Lu, JH, 吕军鸿. Nanomanipulation of extended single-DNA molecules on modified mica surfaces using the atomic force microscopy. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2004, 39(4): 177-180, http://dx.doi.org/10.1016/j.colsurfb.2004.07.013.
[81] 吕军鸿. Positioning isolation and biochemical analysis of single molecules based on nanomanipulation and single-molecule PCR.. Journal of the American Chemical Society. 2004, [82] 吕军鸿, 陈润生. DNA单分子的纳米定位切割与拾取研究. 电子显微学报[J]. 2003, 22(3): 185-188, http://lib.cqvip.com/Qikan/Article/Detail?id=9026786.0.

工作经历

   
工作简历
2018-10~现在, 中国科学院上海高等研究院, 研究员
2014-12~2014-12,马普胶体与界面研究所, 高级研究学者
2013-02~2015-09,牛津大学化学系, 国际居里学者
2012-05~现在, 中国科学院上海应用物理研究所, 研究员
2007-11~2012-08,美国哈佛大学(医学院、Rowland研究所), Research Fellow
2007-03~2007-10,美国密歇根州立大学, 访问学者
2004-07~2008-04,中国科学院上海应用物理研究所, 助研,副研

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