基本信息
黄勋  男  博导  中国科学院遗传与发育生物学研究所
电子邮件: xhuang@genetics.ac.cn
通信地址: 北京市朝阳区北辰西路1号院2号
邮政编码: 100101

研究领域

脂肪代谢调控

教育背景

1997-09--2003-09 University of California, Santa Cruz 博士
1994-09--1997-07 中国科学院微生物研究所 硕士
1990-09--1994-07 厦门大学 学士
学历
-- 研究生
学位
-- 博士

工作经历

   
工作简历
2006-07--今 中科院遗传发育所 ****
2003-07--2006-07 美国斯坦福大学(Stanford University) 博士后

教授课程

信号转导、 分子遗传学

出版信息

   
发表论文
[1] Chen, Siyu, Huang, Xun. Cytosolic lipolysis in non-adipose tissues: energy provision and beyond. FEBS JOURNAL. 2021, [2] Leilei Yang, Jingjing Liang, Sin Man Lam, Ahmet Yavuz, Guanghou Shui, Mei Ding, Xun Huang. Neuronal lipolysis participates in PUFA‐mediated neural function and neurodegeneration. EMBO Reports. 2020, 21(11): [3] Xiao Yang, Jingjing Liang, Long Ding, Xia Li, SinMan Lam, Guanghou Shui, Mei Ding, Xun Huang. Phosphatidylserine synthase regulates cellular homeostasis through distinct metabolic mechanisms.. PLoS Genetics[J]. 2019, 15(12): https://doaj.org/article/283ae42a327b48048daf2a2175f0c770.
[4] Liu, Yuan, Ji, Yuan, Li, Xia, Shui, Guanghou, Huang, Xun. Lipid storage regulator CdsA is essential for Drosophila metamorphosis. JOURNAL OF GENETICS AND GENOMICSnull. 2019, 46(4): 231-234, http://lib.cqvip.com/Qikan/Article/Detail?id=7002171816.
[5] Wei Wang, Jingxue Xin, Xiao Yang, Sin Man Lam, Guanghou Shui, Yong Wang, Xun Huang. Lipid-gene regulatory network reveals coregulations of triacylglycerol with phosphatidylinositol/lysophosphatidylinositol and with hexosyl-ceramide. BBA - Molecular and Cell Biology of Lipids. 2019, 1864(2): 168-180, http://ir.amss.ac.cn/handle/2S8OKBNM/32271.
[6] Yao, Yan, Li, Xia, Wang, Wei, Liu, Zhonghua, Chen, Jianming, Ding, Mei, Huang, Xun. MRT, Functioning with NURF Complex, Regulates Lipid Droplet Size. CELL REPORTS[J]. 2018, 24(11): 2972-2984, https://doaj.org/article/77f2fc9c6ebd47d68e9eeea82500ea72.
[7] Zhao Yannan, Luo Lilan, Xu Jiesi, Xin Peiyong, Guo Hongyan, Wu Jian, Bai Lin, Wang Guodong, Chu Jinfang, Zuo Jianru, Yu Hong, Huang Xun, Li Jiayang. Malate transported from chloroplast to mitochondrion triggers production of ROS and PCD in Arabidopsis thaliana.. Cell research[J]. 2018, 448-461, https://www.webofscience.com/wos/woscc/full-record/WOS:000432028300008.
[8] Ding, Long, Yang, Xiao, Tian, He, Liang, Jingjing, Zhang, Fengxia, Wang, Guodong, Wang, Yingchun, Ding, Mei, Shui, Guanghou, Huang, Xun. Seipin regulates lipid homeostasis by ensuring calcium-dependent mitochondrial metabolism. EMBO JOURNAL[J]. 2018, 37(17): [9] Fan, Wei, Lam, Sin Man, Xin, Jingxue, Yang, Xiao, Liu, Zhonghua, Liu, Yuan, Wang, Yong, Shui, Guanghou, Huang, Xun. Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition. PLOS GENETICS[J]. 2017, 13(3): https://doaj.org/article/c1c43ef857a048fd942933432b16c10b.
[10] Wang, Jinbo, Chitturi, Jyothsna, Ge, Qinglan, Laskova, Valeriya, Wang, Wei, Li, Xia, Ding, Mei, Zhen, Mei, Huang, Xun. The C-elegans COE transcription factor UNC-3 activates lineage-specific apoptosis and affects neurite growth in the RID lineage. DEVELOPMENT[J]. 2015, 142(8): 1447-1457, https://www.webofscience.com/wos/woscc/full-record/WOS:000353590900008.
[11] Liu, Yuan, Wang, Wei, Shui, Guanghou, Huang, Xun. CDP-Diacylglycerol Synthetase Coordinates Cell Growth and Fat Storage through Phosphatidylinositol Metabolism and the Insulin Pathway. PLOS GENETICS[J]. 2014, 10(3): https://doaj.org/article/27aecc4bcb404277a59607b5a35f9943.
[12] Bi, Junfeng, Wang, Wei, Liu, Zhonghua, Huang, Xiahe, Jiang, Qingqing, Liu, George, Wang, Yingchun, Huang, Xun. Seipin Promotes Adipose Tissue Fat Storage through the ER Ca2+-ATPase SERCA. CELL METABOLISM[J]. 2014, 19(5): 861-871, http://dx.doi.org/10.1016/j.cmet.2014.03.028.
[13] Zhou, Bing, Yang, Liu, Li, Shoufeng, Huang, Jialiang, Chen, Haiyang, Hou, Lei, Wang, Jinbo, Green, Christopher D, Yan, Zhen, Huang, Xun, Kaeberlein, Matt, Zhu, Li, Xiao, Huasheng, Liu, Yong, Han, JingDong J. Midlife gene expressions identify modulators of aging through dietary interventions. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2012, 109(19): E1201-E1209, http://202.127.25.144/handle/331004/283.
[14] Bi, Junfeng, Xiang, Yanhui, Chen, Haiyang, Liu, Zhonghua, Groenke, Sebastian, Kuehnlein, Ronald P, Huang, Xun. Opposite and redundant roles of the two Drosophila perilipins in lipid mobilization. JOURNAL OF CELL SCIENCE[J]. 2012, 125(15): 3568-3577, https://www.webofscience.com/wos/woscc/full-record/WOS:000309105800009.
[15] WANG Chao, HUANG Xun. Lipid metabolism and Drosophila sperm development. 中国科学:生命科学英文版. 2012, 55(1): 35-40, http://lib.cqvip.com/Qikan/Article/Detail?id=40814404.
[16] Wang, Chao, Liu, Zhonghua, Huang, Xun. Rab32 Is Important for Autophagy and Lipid Storage in Drosophila. PLOS ONE[J]. 2012, 7(2): https://doaj.org/article/0ac6b9907e614db5ac343b6ab2ba3bf9.
[17] Ma, Zhiguo, Liu, Zhonghua, Huang, Xun. Membrane Phospholipid Asymmetry Counters the Adverse Effects of Sterol Overloading in the Golgi Membrane of Drosophila. GENETICS[J]. 2012, 190(4): 1299-1308, https://www.webofscience.com/wos/woscc/full-record/WOS:000302775700010.
[18] Xun Huang. RIM-9 functions in the UNC-6/UNC-40 pathway to regulate ventral guidance.. 2011, [19] Wang, Chao, Ma, Zhiguo, Scott, Matthew P, Huang, Xun. The cholesterol trafficking protein NPC1 is required for Drosophila spermatogenesis. DEVELOPMENTAL BIOLOGY[J]. 2011, 351(1): 146-155, http://dx.doi.org/10.1016/j.ydbio.2010.12.042.
[20] Xiang, Yanhui, Liu, Zhonghua, Huang, Xun. br regulates the expression of the ecdysone biosynthesis gene npc1. DEVELOPMENTAL BIOLOGY[J]. 2010, 344(2): 800-808, http://www.corc.org.cn/handle/1471x/2405694.
[21] Chen, Haiyang, Liu, Zhonghua, Huang, Xun. Drosophila models of peroxisomal biogenesis disorder: peroxins are required for spermatogenesis and very-long-chain fatty acid metabolism. HUMAN MOLECULAR GENETICS[J]. 2010, 19(3): 494-505, http://www.corc.org.cn/handle/1471x/2409301.
[22] Song, Song, Zhang, Bo, Sun, Hui, Li, Xia, Xiang, Yanhui, Liu, Zhonghua, Huang, Xun, Ding, Mei. A Wnt-Frz/Ror-Dsh Pathway Regulates Neurite Outgrowth in Caenorhabditis elegans. PLOS GENETICS[J]. 2010, 6(8): http://www.corc.org.cn/handle/1471x/2405508.
[23] Zhang Peng, Na Huimin, Liu Zhenglong, Zhang Shuyan, Xue Peng, Chen Yong, Pu Jing, Peng Gong, Huang Xun, Yang Fuquan, Xie Zhensheng, Xu Tao, Xu Pingyong, Ou Guangshuo, Zhang Shaobing O., Liu Pingsheng. Proteomic Study and Marker Protein Identification of Caenorhabditis elegans Lipid Droplets *. Molecular & Cellular Proteomics : MCP. 11(8): 317-328, http://dx.doi.org/10.1074/mcp.M111.016345.

指导学生

已指导学生

项延会  博士研究生  071009-细胞生物学  

陈海洋  博士研究生  071008-发育生物学  

王超  博士研究生  071008-发育生物学  

马志国  博士研究生  071008-发育生物学  

葛庆兰  博士研究生  071008-发育生物学  

田嫄  博士研究生  071008-发育生物学  

宋松  博士研究生  071008-发育生物学  

王金铂  博士研究生  071008-发育生物学  

毕俊峰  博士研究生  071008-发育生物学  

刘元  博士研究生  071008-发育生物学  

现指导学生

刘正隆  博士研究生  071009-细胞生物学  

范玮  博士研究生  071008-发育生物学  

赵雪璠  硕士研究生  071006-神经生物学  

杨雷雷  博士研究生  071008-发育生物学  

姚艳  博士研究生  071008-发育生物学  

丁隆  博士研究生  071008-发育生物学  

杨晓  博士研究生  071008-发育生物学  

许梦瑶  博士研究生  071008-发育生物学  

苏醒  博士研究生  071008-发育生物学  

樊蓉  博士研究生  071008-发育生物学