声镊，超声微流控，复杂介质中的声传播

• 【拟研究课题】：
• 超声操控微纳米颗粒理论研究；
• 基于人工声场的超声操控微纳颗粒的原理、现象、机制研究；
• 基于MEMS工艺的超声微流控关键技术研究；
• 超声与细胞、生物组织的生物效应研究。
• 【背景要求】
• 物理、力学、声学、生物医学工程等专业​；
• 具有一定的数理基础，英语通过CET6。

生物医学超声
声镊，声辐射力，声操控微粒
复杂介质声传播

2003-09--2008-07   武汉大学   博士
1999-09--2003-07   华中师范大学   学士

   

2019-07~2020-12,美国密西西比大学, 访问学者
2008-07~现在, 中科院深圳先进技术研究院, 助理研究员/副研究员/研究员

2018-10-01-今,中国声学学会生物医学超声工程分会, 第八届委员会委员

   

（1） 深圳市自然科学, 一等奖, 市地级, 2019
（2） 国家技术发明奖二等奖, 二等奖, 国家级, 2017
（3） 2016年广东省科学技术发明奖一等奖, 一等奖, 省级, 2016

[1] 蔡飞燕, 张汝钧, 张志强, 林勤, 潘东文, 邱维宝, 郑海荣. 一种超声移液装置及方法. CN114308156A, 2022-04-12.
[2] 蔡飞燕, 夏向向, 李永川, 郑海荣, 周慧. 人工结构超声换能器以及超声装置. CN: CN111842095B, 2021-07-27.
[3] 蔡飞燕, 林勤, 李飞, 夏向向, 周伟, 孟龙, 郑海荣. 声学流体传感器. CN: CN109443406B, 2021-04-09.
[4] 郑海荣, 李飞, 严飞, 蔡飞燕, 孟龙, 肖杨. 超声给药实验装置、超声给药实验方法. CN: CN112553070A, 2021-03-26.
[5] 蔡飞燕, 夏向向, 郑海荣, 牛丽丽, 周慧. 超声针灸装置. CN: CN110478632B, 2021-03-23.
[6] 李飞, 张鹏飞, 蔡飞燕, 郑海荣, 黄继卿, 周伟, 肖杨, 邱维宝, 李永川, 苏敏. 一种声镊装置. CN: CN109939913B, 2021-03-23.
[7] 蔡飞燕, 邹峰, 夏向向, 邱维宝, 李永川, 郑海荣. 超声清洗装置、清洗方法及其应用. CN: CN110560425B, 2021-01-29.
[8] 郑海荣, 夏向向, 蔡飞燕, 周慧. 超声神经调控装置. CN: CN112245818A, 2021-01-22.
[9] 马腾, 杨晔, 王丛知, 李永川, 黄继卿, 蔡飞燕, 刘佳妹, 郑海荣. 一种声镊装置及对微粒的操控方法. CN: CN111013518B, 2020-12-08.
[10] 蔡飞燕, 李飞, 王辰, 邱维宝, 孟龙, 王丛知, 肖杨, 郑海荣. 一种基于时间反转技术操控微粒的系统与方法. CN: CN107050630B, 2020-12-08.
[11] 郑海荣, 李飞, 王珊珊, 蔡飞燕, 孟龙, 苏敏, 黄继卿. 生物3D打印系统与方法. CN: CN111826262A, 2020-10-27.
[12] 蔡飞燕, 夏向向, 郑海荣, 周慧. 一种声波聚焦透镜和超声调控装置. CN: CN111803121A, 2020-10-23.
[13] 蔡飞燕, 夏向向, 郑海荣, 周慧. 超声足疗装置. CN: CN110721066A, 2020-01-24.
[14] 蔡飞燕, 郑海荣, 祝雪丰, 马腾, 李永川, 沈亚西, 杨晔. 一种通信方法及装置. 中国: CN110730042A, 2020-01-24.
[15] 蔡飞燕, 夏向向, 郑海荣, 邹峰, 刘佳妹, 周慧. 超分辨超声显微装置. CN: CN110584713A, 2019-12-20.
[16] 蔡飞燕, 夏向向, 郑海荣, 周慧. 一种超声针灸系统和超声针灸系统控制方法. CN: CN110507918A, 2019-11-29.
[17] 郑海荣, 周慧, 牛丽丽, 孟龙, 蔡飞燕, 夏向向. 一种神经调控装置及方法. CN: CN110368608A, 2019-10-25.
[18] 郑海荣, 夏向向, 蔡飞燕, 马腾, 周慧, 李飞, 刘佳妹, 王丛知. 声波聚焦透镜及超声成像装置. CN: CN209360736U, 2019-09-10.
[19] 郑海荣, 夏向向, 蔡飞燕, 柯满竹, 周慧, 李飞, 许迪, 李永川. 平面透镜和平面透镜的制作方法. CN: CN107870381B, 2019-08-23.
[20] 李永川, 郭瑞彪, 唐彩云, 钱明, 蔡飞燕, 黄继卿, 郑海荣. 一种细胞刺激装置和细胞刺激方法. CN: CN109957508A, 2019-07-02.
[21] 郑海荣, 李飞, 蔡飞燕, 许迪, 夏向向, 林勤, 孟龙, 肖杨, 邱维宝, 李永川, 苏敏, 黄继卿. 一种声驱动的流式细胞检测装置. CN: CN109946217A, 2019-06-28.
[22] 马腾, 蔡飞燕, 李永川, 沈亚西, 祝雪丰, 王丛知, 郑海荣. 一种超声波信号调整方法、装置及超声阵列. CN: CN109620291A, 2019-04-16.
[23] 郑海荣, 夏向向, 蔡飞燕, 马腾, 周慧, 李飞, 刘佳妹, 王丛知. 声波聚焦透镜、超声成像装置及方法. CN: CN109431543A, 2019-03-08.
[24] 蔡飞燕, 张鹏飞, 李飞, 郑海荣, 孟龙, 严飞, 王辰. 体内定点给药装置. CN: CN105854165B, 2019-02-22.
[25] 郑海荣, 夏向向, 蔡飞燕, 柯满竹, 周慧, 李飞, 许迪, 苏敏. 一种基于平面人工结构的超声聚焦透镜. 中国: CN107644636A, 2018.01.30.
[26] 王辰, 蔡飞燕, 李飞, 孟龙, 韦紫君, 康雁, 郑海荣. 一种基于狭缝声子晶体的微粒操控系统及方法. 中国: CN106251925B, 2018-09-07.
[27] 郑海荣, 牛丽丽, 刘新, 孟龙, 邱维宝, 钱明, 蔡飞燕, 肖杨, 王丛知. 声敏感离子通道遗传操作方法及系统. 中国: CN106687587A, 2017-05-17.
[28] 蔡飞燕, 王辰, 耿刘峰, 李飞, 孟龙, 郑海荣. 一种声学流体传感器. 中国: CN106324090A, 2017-01-11.
[29] 蔡飞燕, 张鹏飞, 李飞, 郑海荣, 孟龙, 严飞, 王辰. 体内定点给药装置. 中国: CN205729963U, 2016-11-30.
[30] 陈冕, 郑海荣, 王志勇, 刘新, 蔡飞燕, 孟龙, 严飞, 李飞, 王辰. 一种基于声场操控的纳米粒子靶向递送方法. 中国: CN105535968A, 2016-05-04.
[31] 郑海荣, 李飞, 蔡飞燕, 孟龙, 王辰, 张成祥, 邱维宝, 李永川, 严飞, 牛丽丽, 耿刘峰, 徐超伟. 基于人工结构声场的微流体系统及操控微粒的方法. 中国: CN105214742A, 2016-01-06.
[32] 蔡飞燕, 徐超伟, 李飞, 李永川, 郑海荣. 基于人工周期结构过滤超声波的系统和方法. 中国: CN104259080A, 2015-01-07.
[33] 郑海荣, 孟龙, 蔡飞燕, 牛丽丽, 李飞, 肖杨. 用于对特异性细胞进行筛选的微流控芯片及细胞筛选方法. 中国: CN104195028A, 2014.12.10.
[34] 郑海荣, 孟龙, 蔡飞燕, 牛丽丽, 李飞, 肖杨. 基因导入芯片及基因导入方法. 中国: CN103981090A, 2014.08.13.
[35] 郑海荣, 蔡飞燕, 李飞, 孟龙, 王辰. 基于结构声场操控和筛选颗粒的系统及方法. 中国: CN103203328A, 2013-07-17.

[1] 黄来鑫, 李飞, 蔡飞燕, 孟龙, 周伟, 孔德卿, 郑海荣. Phononic crystal-induced standing Lamb wave for the translation of subwavelength microparticles. Applied Physics Letters[J]. 2022, [2] Joseph Rufo, Feiyan Cai, James Friend, Martin Wiklund, Tony Jun Huang. Acoustofluidics for biomedical applications. NATURE Reviews Methods Primeds[J]. 2022, [3] Lin, Qin, Wang, Jiaqian, Cai, Feiyan, Zhang, Rujun, Zhao, Degang, Xia, Xiangxiang, Wang, Jinping, Zheng, Hairong. A deep learning approach for the fast generation of acoustic holograms. JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA[J]. 2021, 149(4): 2312-2322, https://www.webofscience.com/wos/woscc/full-record/WOS:000636818600004.
[4] Yang, Ye, Wang, Congzhi, Li, Yongchuan, Huang, Jiqing, Cai, Feiyan, Xiao, Yang, Ma, Teng, Zheng, Hairong. Development of Scalable 2D Plane Array for Transcranial Ultrasonic Neuromodulation on Non-Human Primates: An Ex Vivo Study. IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING[J]. 2020, 28(2): 361-369, https://www.webofscience.com/wos/woscc/full-record/WOS:000519699400001.
[5] Xia, Xiangxiang, Li, Yongchuan, Cai, Feiyan, Zhou, Hui, Ma, Teng, Zheng, Hairong. Ultrasonic tunable focusing by a stretchable phase-reversal Fresnel zone plate. APPLIED PHYSICS LETTERS[J]. 2020, 117(2): https://www.webofscience.com/wos/woscc/full-record/WOS:000553037900001.
[6] 郑海荣, 邱维宝, 王丛知, 牛丽丽, 严飞, 蔡飞燕, 邹超, 隆晓菁, 乔阳紫, 肖杨. 超声成像与治疗技术进展与趋势. 中国科学:生命科学[J]. 2020, 50(11): 1256-1267, http://lib.cqvip.com/Qikan/Article/Detail?id=7103245117.
[7] Meng, Long, Cui, Xiaoyu, Dong, Chenyu, Liu, Xiufang, Zhou, Wei, Zhang, Wenjun, Wang, Xinhui, Niu, Lili, Li, Fei, Cai, Feiyan, Wu, Junru, Zheng, Hairong. Microbubble enhanced acoustic tweezers for size-independent cell sorting. APPLIED PHYSICS LETTERS[J]. 2020, 116(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000519603100001.
[8] Ma, Zhichao, Zhou, Yinning, Cai, Feiyan, Meng, Long, Zheng, Hairong, Ai, Ye. Ultrasonic microstreaming for complex-trajectory transport and rotation of single particles and cells. LAB ON A CHIP[J]. 2020, 20(16): 2947-2953, https://www.webofscience.com/wos/woscc/full-record/WOS:000558065700006.
[9] Lin, Qin, Zhou, Wei, Cai, Feiyan, Li, Fei, Xia, Xiangxiang, Wang, Jieqiong, Zhao, Degang, Yan, Fei, Meng, Long, Zheng, Hairong. Trapping of sub-wavelength microparticles and cells in resonant cylindrical shells. APPLIED PHYSICS LETTERS[J]. 2020, 117(5): http://dx.doi.org/10.1063/5.0019758.
[10] Li, Fei, Cai, Feiyan, Zhang, Likun, Liu, Zhengyou, Li, Feng, Meng, Long, Wu, Junru, Li, Jiangyu, Zhang, Xiaofeng, Zheng, Hairong. Phononic-Crystal-Enabled Dynamic Manipulation of Microparticles and Cells in an Acoustofluidic Channel. PHYSICAL REVIEW APPLIED[J]. 2020, 13(4): https://www.webofscience.com/wos/woscc/full-record/WOS:000529842800001.
[11] Lin, Qin, Cai, Feiyan, Li, Fei, Zhao, Degang, Xia, Xiangxiang, Zhou, Wei, Meng, Long, Zheng, Hairong. The compact acoustic liquid sensor based on the circumferential modes of a cylindrical shell. SENSORS AND ACTUATORS A-PHYSICAL[J]. 2020, 304: http://dx.doi.org/10.1016/j.sna.2020.111843.
[12] Meng, Long, Cai, Feiyan, Li, Fei, Zhou, Wei, Niu, Lili, Zheng, Hairong. Acoustic tweezers. JOURNAL OF PHYSICS D-APPLIED PHYSICSnull. 2019, 52(27): https://www.webofscience.com/wos/woscc/full-record/WOS:000467460800001.
[13] Zhou, Wei, Chen, Mian, Liu, Xiufang, Zhang, Wenjun, Cai, Feiyan, Li, Fei, Wu, Junru, Wang, Jinping, Wang, Yang, Huang, Xiaowei, Lin, Zhengrong, Zhou, Hui, Meng, Long, Niu, Lili, Zheng, Hairong. Selective photothermal ablation of cancer cells by patterned gold nanocages using surface acoustic waves. LAB ON A CHIP[J]. 2019, 19(20): 3387-3396, https://www.webofscience.com/wos/woscc/full-record/WOS:000490548200017.
[14] Meng, Long, Liu, Xiufang, Wang, Yuchen, Zhang, Wenjun, Zhou, Wei, Cai, Feiyan, Li, Fei, Wu, Junru, Xu, Lisheng, Niu, Lili, Zheng, Hairong. Sonoporation of Cells by a Parallel Stable Cavitation Microbubble Array. Advanced Science[J]. 2019, 6(17): n/a-n/a, https://doaj.org/article/4ef857a8769141a196bf021d1747f3eb.
[15] Shen, Yaxi, Zhu, Xuefeng, Cai, Feiyan, Ma, Teng, Li, Fei, Xia, Xiangxiang, Li, Yongchuan, Wang, Congzhi, Zheng, Hairong. Active Acoustic Metasurface: Complete Elimination of Grating Lobes for High-Quality Ultrasound Focusing and Controllable Steering. PHYSICAL REVIEW APPLIED[J]. 2019, 11(3): [16] Xia, Xiangxiang, Cai, Feiyan, Li, Fei, Meng, Long, Ma, Teng, Zhou, Hui, Ke, Manzhu, Qiu, Chunyin, Liu, Zhengyou, Zheng, Hairong. Planar Ultrasonic Lenses Formed by Concentric Circular Sandwiched-Ring Arrays. ADVANCED MATERIALS TECHNOLOGIES[J]. 2019, 4(2): [17] Li, Fei, Xia, Xiangxiang, Deng, Zhiting, Lei, Junjun, Shen, Yaxi, Lin, Qin, Zhou, Wei, Meng, Long, Wu, Junru, Cai, Feiyan, Zheng, Hairong. Ultrafast Rayleigh-like streaming in a sub-wavelength slit between two phononic crystal plates. JOURNAL OF APPLIED PHYSICS[J]. 2019, 125(13): https://www.webofscience.com/wos/woscc/full-record/WOS:000463657500015.
[18] Li, Guofeng, Qiu, Weibao, Zhang, Zhiqiang, Jiang, Qiuju, Su, Min, Cai, Ruilin, Li, Yongchuan, Cai, Feiyan, Deng, Zhiting, Xu, Di, Zhang, Huailing, Zheng, Hairong. Noninvasive Ultrasonic Neuromodulation in Freely Moving Mice. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING[J]. 2019, 66(1): 217-224, https://www.webofscience.com/wos/woscc/full-record/WOS:000454110200024.
[19] YaXi Shen, YuGui Peng, Feiyan Cai, Kun Huang, DeGang Zhao, ChengWei Qiu, Hairong Zheng, XueFeng Zhu. Ultrasonic super-oscillation wave-packets with an acoustic meta-lens. Nature Communications[J]. 2019, 10(1): 1-7, http://dx.doi.org/10.1038/s41467-019-11430-3.
[20] Xu, Di, Cai, Feiyan, Chen, Mian, Li, Fei, Wang, Chen, Meng, Long, Xu, Dehui, Wang, Wei, Wu, Junru, Zheng, Hairong. Acoustic manipulation of particles in a cylindrical cavity: Theoretical and experimental study on the effects of boundary conditions. ULTRASONICS[J]. 2019, 93: 18-25, http://ir.siat.ac.cn:8080/handle/172644/14375.
[21] Li, Fei, Xiao, Yang, Lei, Junjun, Xia, Xiangxian, Zhou, Wei, Meng, Long, Niu, Lili, Wu, Junru, Li, Jiangyu, Cai, Feiyan, Zheng, Hairong. Rapid acoustophoretic motion of microparticles manipulated by phononic crystals. APPLIED PHYSICS LETTERS[J]. 2018, 113(17): http://ir.siat.ac.cn:8080/handle/172644/14367.
[22] Wang, Kaiyue, Zhou, Wei, Lin, Zhengrong, Cai, Feiyan, Li, Fei, Wu, Junru, Meng, Long, Niu, Lili, Zheng, Hairong. Sorting of tumour cells in a microfluidic device by multi-stage surface acoustic waves. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 258: 1174-1183, http://ir.siat.ac.cn:8080/handle/172644/14317.
[23] Kaiyue Wang, Wei Zhou, Zhengrong Lin, Feiyan Cai, Fei Li, Junru Wu, Long Meng, Lili Niu, Hairong Zheng. Sorting of tumour cells in a microfluidic device by multi-stage surface acoustic waves. Sensors & Actuators: B. Chemical. 2018, 258: 1174-1183, http://dx.doi.org/10.1016/j.snb.2017.12.013.
[24] Li, Fei, Yan, Fei, Chen, Zhiyi, Lei, Junjun, Yu, Jinsui, Chen, Mian, Zhou, Wei, Meng, Long, Niu, Lili, Wu, Junru, Li, Jiangyu, Cai, Feiyan, Zheng, Hairong. Phononic crystal-enhanced near-boundary streaming for sonoporation. APPLIED PHYSICS LETTERS[J]. 2018, 113(8): http://ir.siat.ac.cn:8080/handle/172644/14348.
[25] Zhang, Jian, Chen, Zhuwen, Wang, Yanding, Zheng, Guangchao, Zheng, Hairong, Cai, Feiyan, Hong, Mei. Influence of the nature of amino acids on the formation of mesoporous LTA-type zeolite. MICROPOROUS AND MESOPOROUS MATERIALS[J]. 2017, 252: 79-89, http://dx.doi.org/10.1016/j.micromeso.2017.05.036.
[26] Zhou, Wei, Wang, Jingjing, Wang, Kaiyue, Huang, Bin, Niu, Lili, Li, Fei, Cai, Feiyan, Chen, Yan, Liu, Xin, Zhang, Xiaoyan, Cheng, Hankui, Kang, Lijun, Meng, Long, Zheng, Hairong. Ultrasound neuro-modulation chip: activation of sensory neurons in Caenorhabditis elegans by surface acoustic waves. LAB ON A CHIP[J]. 2017, 17(10): 1725-1731, https://www.webofscience.com/wos/woscc/full-record/WOS:000401551300003.
[27] Gao, Mengdi, Yu, Yanyan, Zhao, Huixia, Li, Guofeng, Jiang, Hongyang, Wang, Congzhi, Cai, Feiyan, Chan, Leanne LaiHang, Chiu, Bernard, Qian, Wei, Qiu, Weibao, Zheng, Hairong. Simulation Study of an Ultrasound Retinal Prosthesis With a Novel Contact-Lens Array for Noninvasive Retinal Stimulation. IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING[J]. 2017, 25(9): 1605-1611, http://www.chinair.org.cn/handle/1471x/1747541.
[28] Chen, Mian, Cai, Feiyan, Wang, Chen, Wang, Zhiyong, Meng, Long, Li, Fei, Zhang, Pengfei, Liu, Xin, Zheng, Hairong. Observation of Metal Nanoparticles for Acoustic Manipulation. ADVANCED SCIENCE[J]. 2017, 4(5): https://www.webofscience.com/wos/woscc/full-record/WOS:000402740300008.
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已指导学生

郭宁  硕士研究生  081002-信号与信息处理  

梁素姿  硕士研究生  085208-电子与通信工程