主要研究方向为天然产物的化学生物学，综合运用有机化学、生物信息学、分子生物学、生物化学、分析化学、基因工程及代谢工程等学科知识与实验技术手段，进行以下三个方面研究：  

1、真菌活性次生代谢产物生物合成途径及酶催化机制研究； 

2、针对天然产物研究中的关键原始创新点----靶标/药物新结合位点的发现展开研究，阐明活性天然产物的作用靶标及其作用机制； 

3、活性天然产物的合成生物学研究。

   

100701-药物化学
0703Z1-化学生物学
100705-微生物与生化药学

药物化学
化学生物学
生物合成

2011-04--2012-04   加利福尼亚大学洛杉矶分校   访问学者
2004-03--2007-03   中国科学院昆明植物研究所   理学博士
2000-09--2003-07   中国科学院成都生物研究所   理学硕士
1992-09--1996-06   兰州大学生物系   理学学士

   

2022-01~现在, 中国科学院昆明植物研究所, 生物合成与智造专题组 PI
2019-01~现在, 中国科学院昆明植物研究所, 博士生导师
2016-01~现在, 中国科学院昆明植物研究所, 研究员
2009-01~2015-12,中国科学院昆明植物研究所, 副研究员
2007-04~2008-12,中国科学院昆明植物研究所, 助理研究员
2003-07~2003-12,贵州省中国科学院天然产物重点实验室, 研究实习员
1996-07~2000-08,太原瑞丰制药有限公司, 开发部业务主管

生物碱化学

   

（1） 植物化学防御 物质与新农药先导物的研究, 一等奖, 省级, 2013
（2） 虎皮楠中新颖结构生物碱的研究, 一等奖, 省级, 2009
（3） 中国科学院院长奖优秀奖, , 院级, 2007

[1] 郝小江, 姚永刚, 邸迎彤, 罗荣灿, 唐小涵. 牛筋果三内酯A、治疗抗阿尔兹海默症的药物及制备方法和应用. CN: CN112592351B, 2022-02-22.

[2] 杨崇林, 郝小江, 李洋, 徐猛, 丁骁, 晏晨, 邸迎彤, 穆淑珍, 蹇友理, 宋智琴, 郭伟翔. 巨大戟醇及其衍生物在增强溶酶体生成中的应用. CN: CN106619600B, 2019-10-18.

[3] 郝小江, 蔡洁云, 何红平, 黎胜红, 骆世洪, 邸迎彤, 景树溪, 李顺林. 四降三萜类化合物及其制备方法与应用. CN: CN103788078A, 2014-05-14.

[4] 郝小江, 陈铎之, 尹俊林, 彭宗根, 何红平, 蒋建东, 邸迎彤, 张于, 李顺林. 菲啶类衍生物及其药物组合物和其制备方法与应用. CN: CN103145617A, 2013-06-12.

[5] 郝小江, 张于, 何红平, 李艳, 郭伶俐, 邸迎彤. 抗肿瘤生物碱类化合物,其药物组合物及其制备方法和应用. CN: CN102225937A, 2011-10-26.

[6] 郝小江, 郑永唐, 何红平, 黄宁, 谭承建, 李春燕, 邸迎彤, 王睿睿. 三宝木内酯A-D,其药物组合物,制备方法和应用. CN: CN102101864A, 2011-06-22.

[7] 郝小江, 陈全, 刘海洋, 赵丽霞, 邸迎彤, 金海京, 何红平, 乐雯, 高锁, 王晓慧, 杜蕾. 15－氧代绣线菊内酯，其药物组合物和其制备方法及其应用. CN: CN101239964A, 2008-08-13.

   

[1] 邸迎彤. Pepluenone, a new pepluane-type diterpenoid with inhibitory activity on the release of NO from the whole plant of Euphorbia peplus L.. Tetrahedron Letters[J]. 2023, 第 1 作者  通讯作者  
[2] Yan, Ying, Ran, Xiaoqian, Wang, Dan, Zhang, Xiong, Peng, Mingyou, Yan, Xiaoyan, Tang, Lei, Liang, Hong, Qin, Xujie, Di, YingTong, Luo, Rongcan, Hao, XiaoJiang, Yao, YongGang. Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2023, 第 10 作者21(3): 514-519, http://dx.doi.org/10.1039/d2ob01965e.
[3] Guan, ShiPeng, Yang, Ying, Sun, Mao, Cai, Min, Pu, XueXue, Huang, JianYi, Yi, Ping, Liu, Lin, Yuan, MingRui, Cheng, YuanYuan, Di, YingTong. Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L.. PHYTOCHEMISTRY LETTERS[J]. 2023, 第 11 作者  通讯作者  55: 61-66, http://dx.doi.org/10.1016/j.phytol.2023.03.011.
[4] Xu, Wenqiang, Sun, TianYu, Di, Yingtong, Hao, Xiaojiang, Wu, YunDong. Inverse Electron-Demanding Diels-Alder Reactions in the Chemical Synthesis of Prenylated Indole Alkaloids Containing a Bicycle2.2.2diazaoctane Moiety: A Theoretical Study. CHEMISTRY-AN ASIAN JOURNAL. 2023, 第 3 作者18(7): http://dx.doi.org/10.1002/asia.202300063.
[5] Ran, Xiaoqian, Lu, QingYun, Li, YingYao, Pu, XueXue, Guo, Yarong, Yuan, MingRui, Guan, ShiPeng, Sun, Mao, Jiao, Lijin, Yao, YongGang, Di, YingTong, Hao, XiaoJiang, Luo, Rongcan. Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway. HELIYON[J]. 2023, 第 11 作者  通讯作者  9(2): http://dx.doi.org/10.1016/j.heliyon.2023.e13691.
[6] Yan, Ying, Zhou, Qi, Ran, Xiaoqian, Lu, Qingyun, Zhang, Cuishan, Peng, Mingyou, Tang, Lei, Luo, Rongcan, Di, Yingtong, Hao, Xiaojiang. Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2023, 第 9 作者  通讯作者  24(2): http://dx.doi.org/10.3390/ijms24021088.
[7] Cai, Min, Bai, XiaoLin, Zang, HaoJing, Tang, XiaoHan, Yan, Ying, Wan, JiaJia, Peng, MinYou, Liang, Hong, Liu, Lin, Guo, Feng, Zhao, PeiJi, Liao, Xun, Di, YingTong, Hao, XiaoJiang. Quassinoids from Twigs of Harrisonia perforata (Blanco) Merr and Their Anti-Parkinson's Disease Effect. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2023, 第 13 作者  通讯作者  24(22): http://dx.doi.org/10.3390/ijms242216196.
[8] Pu, XueXue, Ran, XiaoQian, Yan, Ying, Lu, QingYun, Li, JinCun, Li, YingYao, Guan, ShiPeng, Cao, MingMing, Liu, Jie, Hao, XiaoJiang, Luo, RongCan, Di, YingTong. Three new jatrophane diterpenoids from Euphorbia peplus Linn. with activity towards autophagic flux. Phytochemistry Letters[J]. 2022, 第 12 作者  通讯作者  50: 141-146, 
[9] Li, YingYao, Yang, Ying, Sun, Mao, Lu, QingYun, Pu, XueXue, Ran, Xiaoqian, Li, DongMei, Wan, JiaJia, Huang, JianYi, Guan, ShiPeng, Luo, Rongcan, Cheng, YuanYuan, Di, YingTong, Hao, XiaoJiang. Jatrophane polyesters from the leaves of Euphorbia peplus with anti-inflammatory activity. PHYTOCHEMISTRY LETTERS[J]. 2022, 第 13 作者  通讯作者  49: 114-119, http://dx.doi.org/10.1016/j.phytol.2022.03.017.
[10] QingYunLu, JiaHuiZhang, YingYaoLi, XueXuePu, CuiShanZhang, ShuaiLiu, JiaJiaWan, YingTongDi, XiaoJiangHao. New Secodaphnane-Type Alkaloids with Cytotoxic Activities fromDaphniphyllum angustifoliumHutch. Natural Products and Bioprospecting[J]. 2021, 第 8 作者11(4): 453-457, http://npb.kib.ac.cn/EN/10.1007/s13659-021-00309-w.
[11] Chen, YanNi, Ding, Xiao, Li, DongMei, Sun, Mao, Yang, Lei, Zhang, Yu, Di, YingTong, Fang, Xin, Hao, XiaoJiang. Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2021, 第 7 作者19(7): 1541-1545, https://www.webofscience.com/wos/woscc/full-record/WOS:000621563000010.
[12] Tang,XiaoHan, Luo,RongCan, Ye,MaoSen, Tang,HongYu, Ma,YuanLiang, Chen,YanNi, Wang,XinMeng, Lu,QingYun, Liu,Shuai, Li,XiaoNian, Yan,Ying, Yang,Jing, Ran,XiaoQian, Fang,Xin, Zhou,Yan, Yao,YongGang, Di,YingTong, Hao,XiaoJiang. Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr. ORGANIC LETTERS[J]. 2021, 第 17 作者23(2): 262-267, 
[13] 姚永刚. Harpertrioate A， an A，B，D-seco-limonoid with promising biological activity against Alzheimer's disease from twigs of Harrisonia perforata （Blanco） Merr （共同一作）. Organic Letters[J]. 2021, 23(2): 262-267, 
[14] Yuan, WenJuan, Gao, WenFen, Zhao, JiangYu, Zhang, Yu, Chen, DuoZhi, Li, ShunLin, Di, YingTong, Hao, XiaoJiang. Diterpenes with potential treatment of vitiligo from the aerials parts of Euphorbia antiquorum L. FITOTERAPIA[J]. 2020, 第 7 作者  通讯作者  144(7): http://ir.kib.ac.cn/handle/151853/72049, http://www.irgrid.ac.cn/handle/1471x/6927915, http://ir.kib.ac.cn/handle/151853/72050, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000537596000004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[15] Gui, PengYan, Yan, XiaoHui, Yuan, WenJuan, Ma, YuanLiang, Ding, Xiao, Liu, Shuai, Di, YingTong, Zhu, WeiMing, Hao, XiaoJiang. 12 beta-Acetyloxyperforatin, a New Limonoid from Harrisonia Perforata. NATURAL PRODUCT RESEARCH[J]. 2019, 第 7 作者  通讯作者  33(19): 2830-2836, http://dx.doi.org/10.1080/14786419.2018.1508139.
[16] Zhang, Jiahui, Cao, Pei, Ma, Yuanliang, Fang, Xin, Yang, Jing, Zhang, Yu, Chen, Duozhi, Gu, Yucheng, Di, Yingtong, Hao, Xiaojiang. Structural Revision of Macropodumine A and Structure of 2-Deoxymacropodumine A, Daphniphyllum Alkaloids with 11-Membered Macrolactone Rings. JOURNAL OF NATURAL PRODUCTS[J]. 2019, 第 9 作者  通讯作者  82(3): 427-430, http://dx.doi.org/10.1021/acs.jnatprod.8b00232.
[17] Duan, XiaoXiang, Qin, Dan, Song, HongChuan, Gao, TianCong, Zuo, ShiHao, Yan, Xiao, Wang, JunQi, Ding, Xiao, Di, YingTong, Dong, JinYan. Irpexlacte A-D, four new bioactive metabolites of endophytic fungus Irpex lacteus DR10-1 from the waterlogging tolerant plant Distylium chinense. PHYTOCHEMISTRY LETTERS[J]. 2019, 第 9 作者32: 151-156, http://dx.doi.org/10.1016/j.phytol.2019.06.001.
[18] YuanLiangMa, XiaoHanTang, WenJuanYuan, XiaoDing, YingTongDi, XiaoJiangHao. Abietane Diterpernoids from the Roots ofEuphorbia ebracteolata. Natural Products and Bioprospecting[J]. 2018, 第 5 作者  通讯作者  8(2): 131-135, http://npb.kib.ac.cn/EN/10.1007/s13659-018-0159-9.
[19] Yi, Wenfang, Chen, Duozhi, Ding, Xiao, Li, Xiaonian, Li, Shunlin, Di, Yingtong, Zhang, Yu, Hao, Xiaojiang. Cytotoxic indole alkaloids from Melodinus khasianus and Melodinus tenuicaudatus. FITOTERAPIA[J]. 2018, 第 6 作者128: 162-168, http://dx.doi.org/10.1016/j.fitote.2018.05.015.
[20] Yan, Ying, Tang, Lei, Hu, Jiaqi, Wang, Jianta, Adelakun, Tiwalade Adegoke, Yang, Dongqiong, Di, Yingtong, Zhang, Yu, Hao, Xiaojiang. Munronin O, a potential activator for plant resistance. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY[J]. 2018, 第 7 作者146: 13-18, http://dx.doi.org/10.1016/j.pestbp.2018.02.001.
[21] Wang, Zhe, Zhao, SiMeng, Hu, YanYun, Feng, Li, Zhao, LiMei, Di, YingTong, Tan, NingHua. Rubipodanones A-D, naphthohydroquinone dimers from rhizomes of &ITRubia podantha &IT. PHYTOCHEMISTRY[J]. 2018, 第 6 作者145: 153-160, https://www.webofscience.com/wos/woscc/full-record/WOS:000423245300018.
[22] Bian, Guangkai, Hou, Anwei, Yuan, Yujie, Hu, Ben, Cheng, Shu, Ye, Ziling, Di, Yingtong, Deng, Zixin, Liu, Tiangang. Metabolic Engineering-Based Rapid Characterization of a Sesquiterpene Cyclase and the Skeletons of Fusariumdiene and Fusagramineol from Fusarium graminearum. ORGANIC LETTERS[J]. 2018, 第 7 作者20(6): 1626-1629, https://doi.org/10.1021/acs.orglett.8b00366.
[23] Zhao, NingDong, Ding, Xiao, Song, Yu, Yang, DongQiong, Adelakun, Tiwalade Adegoke, Qian, WenDan, Zhang, Yu, Di, YingTong, Gao, Fang, Hao, XiaoJiang, Li, ShunLin. Identification of Ingol and Rhamnofolane Diterpenoids from Euphorbia resinifera and Their Abilities to Induce Lysosomal Biosynthesis. JOURNAL OF NATURAL PRODUCTS[J]. 2018, 第 8 作者81(5): 1209-1218, https://www.webofscience.com/wos/woscc/full-record/WOS:000433635500010.
[24] Liu, Shuai, Zhang, Jiahui, Di, Yingtong, Dong, Jinyan, Hao, Xiaojiang. Daphniphyllum alkaloids with cytotoxic activity from Daphniphyllum angustifolium. NATURAL PRODUCT RESEARCH[J]. 2018, 第 3 作者32(18): 2165-2170, https://www.webofscience.com/wos/woscc/full-record/WOS:000441057100007.
[25] 杨智, 孙国太, 邸迎彤, 王跃虎, 胡旭佳. 茶褐牛肝菌化学成分研究. 热带亚热带植物学报[J]. 2018, 第 3 作者26(3): 309-316, http://jtsb.ijournals.cn/jtsb_cn/article/abstract/3839?st=article_issue.
[26] Yuan, WenJuan, Gao, WenFen, Zhang, JiaHui, Cao, Pei, Zhang, Yu, Chen, DuoZhi, Li, ShunLin, Di, YingTong, Hao, XiaoJiang. (+/-)-Perforison A, A Pair of New Chromone Enantiomers from Harrisonia perforata. NATURAL PRODUCT COMMUNICATIONS[J]. 2017, 第 8 作者  通讯作者  12(1): 63-65, http://ir.kib.ac.cn/handle/151853/41892.
[27] Yuan, WenJuan, Ding, Xiao, Wang, Zhe, Yang, BiJuan, Li, XiaoNian, Zhang, Yu, Chen, DuoZhi, Li, ShunLin, Chen, Quan, Di, YingTong, Aisa, Haji Akber, Hao, XiaoJiang. Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A. SCIENTIFICREPORTS[J]. 2017, 第 10 作者  通讯作者  7(1): https://doaj.org/article/e37a28dc25a9453b84cb871969fa2f32.
[28] XiaoHuiYan, Yi, Ping, Cao, Pei, Yang, ShiYing, Fang, Xin, Zhang, Yu, Wu, Bin, Leng, Ying, Di, YingTong, Lv, Yang, Hao, XiaoJiang. 16-nor Limonoids from Harrisonia perforata as promising selective 11 beta-HSD1 inhibitors. SCIENTIFIC REPORTS[J]. 2016, 第 9 作者  通讯作者  6: http://ir.kib.ac.cn/handle/151853/33667.
[29] XiaoHui Yan, Ping Yi, Pei Cao, ShiYing Yang, Xin Fang, Yu Zhang, Bin Wu, Ying Leng, YingTong Di, Yang Lv, XiaoJiang Hao. 16-nor Limonoids from Harrisonia perforata as promising selective 11 β -HSD1 inhibitors. SCIENTIFIC REPORTS. 2016, 第 9 作者6: 
[30] Tian, Dong Song, Yi, Ping, Xia, Lei, Xiao, Xin, Fan, Yi Min, Gu, Wei, Huang, Lie Jun, BenDavid, Yaacov, Di, Ying Tong, Yuan, Chun Mao, Hao, Xiao Jiang. Garmultins A-G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora. ORGANIC LETTERS[J]. 2016, 第 9 作者18(22): 5904-5907, http://www.irgrid.ac.cn/handle/1471x/1175722.
[31] Li, XiaoHui, Zhang, Yu, Zhang, JiaHui, Li, XiaoNian, Cao, MingMing, Di, YingTong, Peng, ZongGen, Jiang, JianDong, Hao, XiaoJiang. Myritonines A-C, Alkaloids from Myrioneuron tonkinensis Based on a Novel Hexacyclic Skeleton. JOURNAL OF NATURAL PRODUCTS[J]. 2016, 第 6 作者79(4): 1203-1207, http://ir.kib.ac.cn/handle/151853/26223.
[32] Yuan, WenJuan, Yang, GuoPing, Zhang, JiaHui, Zhang, Yu, Chen, DuoZhi, Li, ShunLin, Di, YingTong, Hao, XiaoJiang. Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata. PHYTOCHEMISTRY LETTERS[J]. 2016, 第 7 作者  通讯作者  18(1): 176-179, http://dx.doi.org/10.1016/j.phytol.2016.10.008.
[33] Li, Yang, Xu, Meng, Ding, Xiao, Yan, Chen, Song, Zhiqin, Chen, Lianwan, Huang, Xiahe, Wang, Xin, Jian, Youli, Tang, Guihua, Tang, Changyong, Di, Yingtong, Mu, Shuzhen, Liu, Xuezhao, Liu, Kai, Li, Ting, Wang, Yingchun, Miao, Long, Guo, Weixiang, Hao, Xiaojiang, Yang, Chonglin. Protein kinase C controls lysosome biogenesis independently of mTORC1. NATURE CELL BIOLOGY[J]. 2016, 第 12 作者18(10): 1065-1077, http://www.irgrid.ac.cn/handle/1471x/1140918.
[34] Liu, YongQin, Di, YingTong, Wang, YueHu, Hao, XiaoJiang, Hu, XuJia. New Compounds from the Roots and Stems of Trigonostemonlii and Their Cytotoxic Activities. HELVETICA CHIMICA ACTA[J]. 2016, 第 2 作者99(7): 558-561, http://www.irgrid.ac.cn/handle/1471x/1109883.
[35] Zhang, JiaHui, JingGuo, Jing, Yuan, Yu Xi, Fu, YanHui, Gu, YuCheng, Zhang, Yu, Chen, DuoZhi, Li, ShunLin, Di, YingTong, Hao, XiaoJiang. Four new tetracyclic alkaloids with cis-decahydroquinoline motif from Myrioneuron effusum. FITOTERAPIA[J]. 2016, 第 9 作者  通讯作者  112: 217-221, http://dx.doi.org/10.1016/j.fitote.2016.06.006.
[36] Qin, XuJie, Yan, Huan, Ni, Wei, Yu, MuYuan, Khan, Afsar, Liu, Hui, Zhang, HongXia, He, Li, Hao, XiaoJiang, Di, YingTong, Liu, HaiYang. Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone. SCIENTIFIC REPORTS[J]. 2016, 第 10 作者  通讯作者  6: http://www.irgrid.ac.cn/handle/1471x/1109614.
[37] Chang, YaoWen, Yuan, ChunMao, Zhang, Jing, Liu, Shuai, Cao, Pei, Hua, HuiMing, Di, YingTong, Hao, XiaoJiang. Speramides A-B, two new prenylated indole alkaloids from the freshwater-derived fungus Aspergillus ochraceus KM007. TETRAHEDRON LETTERS[J]. 2016, 第 7 作者  通讯作者  57(45): 4952-4955, http://dx.doi.org/10.1016/j.tetlet.2016.09.071.
[38] Chunxiang Wang, Xiao Ding, ShiXiu Feng, Qiunong Guan, XiaoPing Zhang, Caigan Du, YingTong Di, Tao Chen. Seven New Tetrahydroanthraquinones from the Root of Prismatomeris connata and Their Cytotoxicity against Lung Tumor Cell Growth. MOLECULES[J]. 2015, 第 7 作者20(12): 22565-22577, https://doaj.org/article/d07fda9194324dccba0c4834ca82a821.
[39] Chen, Duozhi, Cai, Jieyun, Yin, Junlin, Jiang, Jiandong, Jing, Chenxu, Zhu, Yanping, Cheng, Junjun, Di, Yingtong, Zhang, Yu, Cao, Mingming, Li, Shunlin, Peng, Zonggen, Hao, Xiaojiang. Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors. FUTURE MEDICINAL CHEMISTRY[J]. 2015, 第 8 作者7(5): 561-570, http://www.irgrid.ac.cn/handle/1471x/963675.
[40] Chang, YaoWen, Yuan, ChunMao, Zhang, Jing, Zhang, Yu, Hua, HuiMing, Di, YingTong, Hao, XiaoJiang. A novel gamma-lactone derivative from the twigs of Turraea pubescens. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES[J]. 2015, 第 6 作者70(8): 533-536, http://ir.kib.ac.cn/handle/151853/25086.
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[100] Zhu, Feng, Di, YingTong, Liu, LingLi, Zhang, Qiang, Fang, Xin, Yang, TingQuan, Hao, XiaoJiang, He, HongPing. Cytotoxic Neoclerodane Diterpenoids from Scutellaria barbata. JOURNAL OF NATURAL PRODUCTS[J]. 2010, 第 2 作者73(2): 233-236, http://dx.doi.org/10.1021/np900309p.
[101] Guo, Jie, He, HongPing, Fang, Xin, Di, YingTong, Li, ShunLin, Zhang, Zhen, Leng, Ying, Hua, HuiMing, Hao, XiaoJiang. Kansuinone, a novel euphane-type triterpene from Euphorbia kansui. TETRAHEDRON LETTERS[J]. 2010, 第 4 作者51(48): 6286-6289, http://dx.doi.org/10.1016/j.tetlet.2010.09.099.
[102] Guo, Jie, Fang, Xin, Di, Ying Tong, Hua, Hui Ming, Hao, Xiao Jiang. Kansuinine J, a new macrocyclic diterpenoid from the roots of Euphorbia kansui. CHINESE CHEMICAL LETTERS[J]. 2010, 第 3 作者21(8): 943-946, http://lib.cqvip.com/Qikan/Article/Detail?id=35077983.
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[132] 任艳丽, 唐前瑞, 邸迎彤, 张桢, 何红平, 李顺林, 郝小江. 灰毛浆果楝的化学成分研究. 中草药[J]. 2008, 第 3 作者39(9): 1302-1303, http://lib.cqvip.com/Qikan/Article/Detail?id=28265032.
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[135] Zhang, Yu, He, Hongping, Di, Yingtong, Mu, Shuzhen, Wang, Yuehu, Wang, Junsong, Li, Chunshun, Kong, Ningchuan, Gao, Suo, Hao, Xiaojiang. Paxiphyllines a and b, new alkaloids from Daphniphyllum paxianum. TETRAHEDRON LETTERS[J]. 2007, 第 3 作者48(52): 9104-9107, http://dx.doi.org/10.1016/j.tetlet.2007.10.136.
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（ 1 ） penamycin 生物合成途径的研究, 负责人, 中国科学院计划, 2014-03--2017-02
（ 2 ） 基于自噬—溶酶体通路的抗肿瘤先导化合物川楝素构效关系及其作用靶点的研究, 负责人, 地方任务, 2015-01--2017-12
（ 3 ） 南欧大戟中巨大戟醇生物合成基因簇初探, 负责人, 研究所自选, 2015-01--2015-12
（ 4 ） 生物活性分子的发现、修饰及应用, 参与, 国家任务, 2015-01--2019-12
（ 5 ） 中亚地区中药资源评价及活性, 参与, 中国科学院计划, 2014-01--2017-03
（ 6 ） 真菌中二聚烯化吲哚生物碱生物的生物合成机制与其药用功能导向的 生物合成途径理性改造, 负责人, 国家任务, 2016-01--2019-12
（ 7 ） 靶向昆虫烟碱乙酰胆碱受体的C-25型苦木素作用机制与其杀虫功能导 向的理性设计, 负责人, 国家任务, 2018-01--2021-12
（ 8 ） 十种药食同源芳香植物的关键技术开发与应用, 负责人, 地方任务, 2018-01--2020-12
（ 9 ） 对叶大戟基因组测序及其中假白榄烷二萜酯 生物合成基因的分离, 负责人, 中国科学院计划, 2018-06--2020-05
（ 10 ） 靶向自噬-溶酶体通路用于防治AD的小分子激活剂20-去氧巨大戟 烷酯衍生物的设计合成及作用机制挖掘, 负责人, 地方任务, 2022-06--2025-05
（ 11 ） 云南高山植物美白等功效成分的研究, 负责人, 企业委托, 2022-04--2024-12

（1）烯化吲哚生物碱生物合成途径研究   第三十二届全国化学会   2021-04-19

已指导学生

马元良  硕士研究生  078001-药物化学  

陆庆云  硕士研究生  078001-药物化学  

张翠珊  硕士研究生  078001-药物化学  

刘帅  博士研究生  100701-药物化学  

现指导学生

周琪  硕士研究生  078001-药物化学  

袁名睿  博士研究生  100701-药物化学  

刘林  硕士研究生  078001-药物化学  

郭峰  硕士研究生  105500-药学  

姚佩彤  硕士研究生  105500-药学  

梁弘  博士研究生  100701-药物化学