蛋白质翻译后修饰方法研究

蛋白质糖基化及其在转化医学中的应用
新型蛋白质结构活性探针反应研究

蛋白质氧化与疾病关联性研究

有机化学、应用化学、化学生物学背景

070302-分析化学
0703Z1-化学生物学

蛋白质糖基化，蛋白-蛋白相互作用及蛋白质分泌组学，化学生物学
化学蛋白质组学

2007-09--2013-07   中国科学院大连化学物理研究所   理学博士
2003-09--2007-07   天津大学   理学学士

2013.07-2018.06  中国科学院大连化学物理研究所   副研究员 

2018.07---             中国科学院大连化学物理研究所   研究员 

   

[1] Li, Jiaying, Zhou, Jiahua, Tian, Kailu, Zhu, He, Chen, Yao, Huang, Yangyu, Wang, Guosheng, Gong, Zhou, Qin, Hongqiang, Ye, Mingliang, Xu, Hao. ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2023, 第 9 作者  通讯作者  http://dx.doi.org/10.1021/jacs.2c12653.
[2] Jia, Xiaochen, Zhang, Hongyan, Qin, Hongqiang, Li, Kuikui, Liu, Xiaoyan, Wang, Wenxia, Ye, Mingliang, Yin, Heng. Protein O-GlcNAcylation impairment caused by N-acetylglucosamine phosphate mutase deficiency leads to growth variations in Arabidopsis thaliana. PLANT JOURNAL[J]. 2023, 第 3 作者114(3): 613-635, http://dx.doi.org/10.1111/tpj.16156.
[3] 李佳颖, 王国胜, 叶明亮, 秦洪强. 活性导向的化学探针在氨基酸反应活性表征中的应用进展. 色谱[J]. 2023, 第 4 作者41(1): 14-23, http://lib.cqvip.com/Qikan/Article/Detail?id=7108709453.
[4] 方正, 秦洪强, 叶明亮. 提高N-连接完整糖肽鉴定准确性的母离子特征筛选策略. 质谱学报[J]. 2023, 第 2 作者44(3): 377-386, https://zpxb.xml-journal.net/article/doi/10.7538/zpxb.2022.0134.
[5] Ruan, Hongxia, Li, Xuejuan, Zhou, Lina, Zheng, Zihan, Hua, Rulin, Wang, Xu, Wang, Yuan, Fan, Yujie, Guo, Shuwen, Wang, Lihua, Ur Rahman, Shafiq, Wang, Ziwei, Wei, Yuyuan, Yu, Shuangyan, Zhang, Rongzhi, Cheng, Qian, Sheng, Jie, Li, Xue, Liu, Xiaoyan, Yuan, Ruqiang, Zhang, Xiaoyan, Chen, Lihong, Xu, Guowang, Guan, Youfei, Nie, Jing, Qin, Hongqiang, Zheng, Feng. Melatonin decreases GSDME mediated mesothelial cell pyroptosis and prevents peritoneal fibrosis and ultrafiltration failure. SCIENCE CHINA-LIFE SCIENCES. 2023, 第 26 作者  通讯作者  http://dx.doi.org/10.1007/s11427-022-2365-1.
[6] Wu, RuiQi, Lao, XiangMing, Chen, DongPing, Qin, Hongqiang, Mu, Ming, Cao, WenJie, Deng, Jia, Wan, ChaoChao, Zhan, WanYu, Wang, JunCheng, Xu, Li, Chen, MinShan, Gao, Qiang, Zheng, Limin, Wei, Yuan, Kuang, DongMing. Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma. IMMUNITY[J]. 2023, 第 4 作者56(1): 180-+, http://dx.doi.org/10.1016/j.immuni.2022.11.014.
[7] Zhang, Jinrui, Zhang, Ge, Zhang, Wenjing, Bai, Lu, Wang, Luning, Li, Tiantian, Yan, Li, Xu, Yang, Chen, Dan, Gao, Wenting, Gao, Chuanzhou, Chen, Chaoqun, Ren, Menglin, Jiao, Yuexia, Qin, Hongqiang, Sun, Yu, Zhi, Lili, Qi, Yangfan, Zhao, Jinyao, Liu, Quentin, Liu, Han, Wang, Yang. Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer. CELL DEATH AND DIFFERENTIATION[J]. 2022, 第 15 作者29(11): 2247-2261, http://dx.doi.org/10.1038/s41418-022-01012-0.
[8] Ji, Yanli, Sun, Lin, Chen, Yao, Qin, Hongqiang, Xuan, Weimin. Sirtuin-Derived Covalent Binder for the Selective Recognition of Protein Crotonylation. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, 第 4 作者  通讯作者  61(31): http://dx.doi.org/10.1002/anie.202205522.
[9] Chen, Yao, Tang, Feng, Qin, Hongqiang, Yue, Xuyang, Nie, Yongzhan, Huang, Wei, Ye, Mingliang. Endo-M Mediated Chemoenzymatic Approach Enables Reversible Glycopeptide Labeling for O-GlcNAcylation Analysis. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, 第 3 作者  通讯作者  http://dx.doi.org/10.1002/anie.202117849.
[10] Wang, Qi, Li, Zhouxian, Zhou, Jiahua, Wang, Yan, Wang, Keyun, Qin, Hongqiang, Ye, Mingliang. Chemical Depletion of Histidine-Containing Peptides Allows Identification of More Low-Abundance Methylation Sites from Proteome Samples. JOURNAL OF PROTEOME RESEARCH[J]. 2021, 第 6 作者20(5): 2497-2505, http://dx.doi.org/10.1021/acs.jproteome.0c00976.
[11] Liu, Luyao, Zhu, Bin, Fang, Zheng, Zhang, Na, Qin, Hongqiang, Guo, Zhimou, Liang, Xinmiao, Yao, Zhenzhen, Ye, Mingliang. Automated Intact Glycopeptide Enrichment Method Facilitating Highly Reproducible Analysis of Serum Site-Specific N-Glycoproteome. ANALYTICAL CHEMISTRY[J]. 2021, 第 5 作者93(20): 7473-7480, http://dx.doi.org/10.1021/acs.analchem.1c00645.
[12] 刘璐瑶, 秦洪强, 叶明亮. 完整糖基化肽段的富集与质谱解析新技术研究进展. 色谱[J]. 2021, 第 2 作者39(10): 1045-1054, http://lib.cqvip.com/Qikan/Article/Detail?id=7105506360.
[13] Yue, Xuyang, Qin, Hongqiang, Chen, Yao, Fang, Zheng, Liu, Luyao, Zhu, He, Liu, Xiaoyan, Zhou, Jiahua, Tian, Kailu, Qiao, Xiaoqiang, Ye, Mingliang. Highly Efficient Enrichment of O-GalNAc Glycopeptides by Using Immobilized Metal Ion Affinity Chromatography. ANALYTICAL CHEMISTRY[J]. 2021, 第 2 作者  通讯作者  93(21): 7579-7587, http://dx.doi.org/10.1021/acs.analchem.0c05236.
[14] 毛家维, 王科云, 刘璐瑶, 秦洪强, 叶明亮. 提高开放性检索鉴定灵敏度的互补离子谱图策略. 质谱学报[J]. 2020, 第 4 作者41(1): 11-18, https://zpxb.xml-journal.net/article/doi/10.7538/zpxb.2018.0155.
[15] Li, Minmin, Xiong, Yuting, Lu, Wenqi, Wang, Xue, Liu, Yunhai, Na, Bing, Qin, Haijuan, Tang, Mingliang, Qin, Hongqiang, Ye, Mingliang, Liang, Xinmiao, Qing, Guangyan. Functional Nanochannels for Sensing Tyrosine Phosphorylation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2020, 第 9 作者142(38): 16324-16333, https://www.webofscience.com/wos/woscc/full-record/WOS:000575684100026.
[16] 周家华, 秦洪强, 叶明亮. 羰基化蛋白质组学分析进展. 分析测试学报[J]. 2020, 第 2 作者39(1): 82-88, http://lib.cqvip.com/Qikan/Article/Detail?id=7101155751.
[17] Zhang, Na, An, Jun, Qin, Hongqiang, Wang, Yan, Fang, Zheng, Ji, Yinqun, Ye, Mingliang. A Mass-Spectrometry-Based Antibody-Free Approach Enables the Quantification of D-Dimer in Plasma. JOURNAL OF PROTEOME RESEARCH[J]. 2020, 第 3 作者19(8): 3143-3152, https://www.webofscience.com/wos/woscc/full-record/WOS:000562081000022.
[18] Wang, Shuyue, Qin, Hongqiang, Mao, Jiawei, Fang, Zheng, Chen, Yao, Zhang, Xiaolei, Hu, Lianghai, Ye, Mingliang. Profiling of Endogenously Intact N-Linked and O-Linked Glycopeptides from Human Serum Using an Integrated Platform. JOURNAL OF PROTEOME RESEARCH[J]. 2020, 第 2 作者19(4): 1423-1434, https://www.webofscience.com/wos/woscc/full-record/WOS:000526337800007.
[19] Jia, Xiaochen, Qin, Hongqiang, Bose, Santosh Kumar, Liu, Tongmei, He, Jinxia, Xie, Shangqiang, Ye, Mingliang, Yin, Heng. Proteomics analysis reveals the defense priming effect of chitosan oligosaccharides in Arabidopsis-Pst DC3000 interaction. PLANT PHYSIOLOGY AND BIOCHEMISTRY[J]. 2020, 第 2 作者149: 301-312, http://dx.doi.org/10.1016/j.plaphy.2020.01.037.
[20] Wang, Shuyue, Qin, Hongqiang, Dong, Jing, Hu, Lianghai, Ye, Mingliang. Multi-histidine functionalized material for the specific enrichment of sialylated glycopeptides. JOURNAL OF CHROMATOGRAPHY A[J]. 2020, 第 2 作者1627: http://dx.doi.org/10.1016/j.chroma.2020.461422.
[21] Sheng, Qianying, Wang, Cunli, Li, Xiaopei, Qin, Hongqiang, Ye, Mingliang, Xiong, Yuting, Wang, Xue, Li, Xiuling, Lan, Minbo, Li, Junyan, Ke, Yanxiong, Qing, Guangyan, Liang, Xinmiao. Highly Efficient Separation of Methylated Peptides Utilizing Selective Complexation between Lysine and 18-Crown-6. ANALYTICAL CHEMISTRY[J]. 2020, 第 4 作者92(23): 15663-15670, https://www.webofscience.com/wos/woscc/full-record/WOS:000596727600052.
[22] Li, Yanan, Qin, Hongqiang, Ye, Mingliang. An overview on enrichment methods for cell surface proteome profiling. JOURNAL OF SEPARATION SCIENCE. 2020, 第 2 作者43(1): 292-312, http://dx.doi.org/10.1002/jssc.201900700.
[23] Qin, Hongqiang, Dong, Xuefang, Mao, Jiawei, Chen, Yao, Dong, Mingming, Wang, Liming, Guo, Zhimou, Liang, Xinmiao, Ye, Mingliang. Highly Efficient Analysis of Glycoprotein Sialylation in Human Serum by Simultaneous Quantification of Glycosites and Site-Specific Glycoforms. JOURNAL OF PROTEOME RESEARCH[J]. 2019, 第 1 作者18(9): 3439-3446, 
[24] Mao, Jiawei, You, Xin, Qin, Hongqiang, Wang, Chenye, Wang, Liming, Ye, Mingliang. A New Searching Strategy for the Identification of O-Linked Glycopeptides. ANALYTICAL CHEMISTRY[J]. 2019, 第 3 作者91(6): 3852-3859, http://cas-ir.dicp.ac.cn/handle/321008/165732.
[25] Hongqiang Qin. Proteomics Analysis of Site-specific Glycoforms by a Virtual Multistage Mass Spectrometry Metho. Analytica Chimica Acta. 2019, 第 1 作者
[26] Qin, Hongqiang, Chen, Yao, Mao, Jiawei, Cheng, Kai, Sun, Deguang, Dong, Mingming, Wang, Lu, Wang, Liming, Ye, Mingliang. Proteomics analysis of site-specific glycoforms by a virtual multistage mass spectrometry method. ANALYTICA CHIMICA ACTA[J]. 2019, 第 1 作者1070: 60-68, http://cas-ir.dicp.ac.cn/handle/321008/171875.
[27] You, Xin, Qin, Hongqiang, Ye, Mingliang. Recent advances in methods for the analysis of protein o-glycosylation at proteome level. JOURNAL OF SEPARATION SCIENCE[J]. 2018, 第 2 作者41(1): 248-261, http://cas-ir.dicp.ac.cn/handle/321008/168498.
[28] Tian, Yu, Han, Zhao, Ma, Kexin, Qin, Hongqiang, Zhang, Rixin, Sun, Deguang, Wang, Haibo, Dong, Chengyong, Dong, Bing, Wang, Liming, Ye, Mingliang, Liang, Rui. LCN1 is highly expressed in cholangiocarcinoma patients and indicates poor prognosis. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE[J]. 2018, 第 4 作者11(10): 10917-10922, http://www.corc.org.cn/handle/1471x/2373132.
[29] You, Xin, Qin, Hongqiang, Mao, Jiawei, Tian, Yu, Dong, Mingming, Guo, Zhimou, Liang, Xinmiao, Wang, Liming, Jin, Yan, Ye, Mingliang. Highly Efficient Identification of O-GalNAc Glycosylation by an Acid-Assisted Glycoform Simplification Approach. PROTEOMICS[J]. 2018, 第 2 作者18(17): https://www.webofscience.com/wos/woscc/full-record/WOS:000443407000005.
[30] You, Xin, Yao, Yating, Mao, Jiawei, Qin, Hongqiang, Liang, Xinmiao, Wang, Liming, Ye, Mingliang. Chemoenzymatic Approach for the Proteomics Analysis of Mucin-Type Core-1 O-Glycosylation in Human Serum. ANALYTICAL CHEMISTRY[J]. 2018, 第 4 作者90(21): 12714-12722, http://cas-ir.dicp.ac.cn/handle/321008/166628.
[31] Wu, Sijin, Zhang, Keren, Qin, Hongqiang, Niu, Mingshan, Zhao, Weijie, Ye, Mingliang, Zou, Hanfa, Yang, Yongliang. Caffeic acid phenethyl ester (CAPE) revisited: Covalent modulation of XPO1/CRM1 activities and implication for its mechanism of action. CHEMICAL BIOLOGY & DRUG DESIGN[J]. 2017, 第 3 作者89(5): 655-662, https://www.webofscience.com/wos/woscc/full-record/WOS:000399734600001.
[32] Dong, Xuefang, Qin, Hongqiang, Mao, Jiawei, Yu, Dongping, Li, Xiuling, Shen, Aijin, Yan, Jingyu, Yu, Long, Guo, Zhimou, Ye, Mingliang, Zou, Hanfa, Liang, Xinmiao. In-Depth Analysis of Glycoprotein Sialylation in Serum Using a Dual-Functional Material with Superior Hydrophilicity and Switchable Surface Charge. ANALYTICAL CHEMISTRY[J]. 2017, 第 2 作者89(7): 3966-3972, http://cas-ir.dicp.ac.cn/handle/321008/169302.
[33] Dong, Mingming, Bian, Yangyang, Wang, Yan, Dong, Jing, Yao, Yating, Deng, Zhenzhen, Qin, Hongqiang, Zou, Hanfa, Ye, Mingliang. Sensitive, Robust, and Cost-Effective Approach for Tyrosine Phosphoproteome Analysis. ANALYTICAL CHEMISTRY[J]. 2017, 第 7 作者89(17): 9307-9314, http://cas-ir.dicp.ac.cn/handle/321008/149957.
[34] Cong, Yuting, Hu, Lianghai, Zhang, Zhang, Gao, Yin, Dong, Mingming, Qin, Hongqiang, Ye, Mingliang, Gu, Jingkai, Zou, Hanfa. Analysis of therapeutic monoclonal antibody glycoforms by mass spectrometry for pharmacokinetics study. TALANTA[J]. 2017, 第 6 作者165: 664-670, http://cas-ir.dicp.ac.cn/handle/321008/169566.
[35] Qin, Hongqiang, Cheng, Kai, Zhu, Jun, Mao, Jiawei, Wang, Fangjun, Dong, Mingming, Chen, Rui, Guo, Zhimou, Liang, Xinmiao, Ye, Mingliang, Zou, Hanfa. Proteomics Analysis of O-GaINAc Glycosylation in Human Serum by an Integrated Strategy. ANALYTICAL CHEMISTRY[J]. 2017, 第 1 作者89(3): 1469-1476, http://cas-ir.dicp.ac.cn/handle/321008/169606.
[36] Wu, Jian, Qin, Hongqiang, Li, Ting, Cheng, Kai, Dong, Jiaqiang, Tian, Miaomiao, Chai, Na, Guo, Hao, Li, Jinjing, You, Xin, Dong, Mingming, Ye, Mingliang, Nie, Yongzhan, Zou, Hanfa, Fan, Daiming. Characterization of site-specific glycosylation of secreted proteins associated with multi-drug resistance of gastric cancer. ONCOTARGET[J]. 2016, 第 2 作者7(18): 25315-25327, http://cas-ir.dicp.ac.cn/handle/321008/148378.
[37] Peng, Jiaxi, Zhang, Hongyan, Li, Xin, Liu, Shengju, Zhao, Xingyun, Wu, Jing, Kang, Xiaohui, Qin, Hongqiang, Pan, Zaifa, Wu, Renan. Dual-Metal Centered Zirconium-Organic Framework: A Metal-Affinity Probe for Highly Specific Interaction with Phosphopeptides. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 第 8 作者8(51): 35012-35020, http://cas-ir.dicp.ac.cn/handle/321008/151845.
[38] Yao, Yating, Huang, Junfeng, Cheng, Kai, Pan, Yanbo, Qin, Hongqiang, Ye, Mingliang, Zou, Hanfa. Specific Enrichment of Peptides with N-Terminal Serine/Threonine by a Solid-Phase Capture-Release Approach for Efficient Proteomics Analysis. ANALYTICAL CHEMISTRY[J]. 2015, 第 5 作者87(22): 11353-11360, https://www.webofscience.com/wos/woscc/full-record/WOS:000365151000027.
[39] Dong, Mingming, Bian, Yangyang, Dong, Jing, Wang, Keyun, Liu, Zheyi, Qin, Hongqiang, Ye, Mingliang, Zou, Hanfa. Selective Enrichment of Cysteine-Containing Phosphopeptides for Subphosphoproteome Analysis. JOURNAL OF PROTEOME RESEARCH[J]. 2015, 第 6 作者14(12): 5341-5347, http://dx.doi.org/10.1021/acs.jproteome.5b00830.
[40] 黄俊峰, 万昊, 姚亚婷, 李吉楠, 程凯, 毛家维, 陈津, 王, 秦洪强, 张维冰, 叶明亮, 邹汉法. Highly Efficient Release of Glycopeptides from Hydrazide Beads by Hydroxylamine Assisted PNGase F Deglycosylation for N‑Glycoproteome Analysis. ANALYTICAL CHEMISTRY[J]. 2015, 第 9 作者87: 10199, http://cas-ir.dicp.ac.cn/handle/321008/147820.
[41] 张章, 孙德光, 丛宇婷, 毛家维, 黄俊峰, 秦洪强, 刘静, 黄光, 王立明, 叶明亮, 邹汉法. Amine Chemistry Method for Selective Enrichment of N‑Linked Glycopeptides for Glycoproteomics Analysis. JOURNAL OF PROTEOME RESEARCH[J]. 2015, 第 6 作者14(1): 3892, http://cas-ir.dicp.ac.cn/handle/321008/143750.
[42] 由昕, 秦洪强, 叶明亮, 邹汉法. AN INTEGRATED METHOD FOR DETERMINATION OF SITE-SPECIFIC GLYCOFORMS IN EPITHELIAL-MESENCHYMAL TRANSITION (EMT) PROCESS. 43rd international symposium on high performance liquid phase separations and related techniques. 2015, 第 2 作者http://cas-ir.dicp.ac.cn/handle/321008/143429.
[43] 秦洪强, 程凯, 朱俊, 由昕, 毛家维, 叶明亮, 邹汉法. Development of Methods for Site-Specifi Analysis of N-Linked Protein Glycosylation. hupo 2015 world congress. 2015, 第 1 作者http://cas-ir.dicp.ac.cn/handle/321008/143433.
[44] 陈贵夫, 王峰, 王业红, 张晓辰, 秦洪强, 邹汉法, 徐杰. Imine—linked conjugated organic polymer bearing bis(imino) pyridine ligands and its catalytic application in C–C coupling reactions. CHINESE JOURNAL OF CATALYSIS催化学报[J]. 2015, 第 5 作者35(1): 540, http://cas-ir.dicp.ac.cn/handle/321008/144546.
[45] Huang, Junfeng, Wan, Hao, Yao, Yating, Li, Jinan, Cheng, Kai, Mao, Jiawei, Chen, Jin, Wang, Yan, Qin, Hongqiang, Zhang, Weibing, Ye, Mingliang, Zou, Hanfa. Highly Efficient Release of Glycopeptides from Hydrazide Beads by Hydroxylamine Assisted PNGase F Deglycosylation for N-Glycoproteome Analysis. ANALYTICAL CHEMISTRY[J]. 2015, 第 9 作者87(20): 10199-10204, https://www.webofscience.com/wos/woscc/full-record/WOS:000363348300008.
[46] 张章, 丛宇婷, 黄俊峰, 秦洪强, 刘静, 黄光, 叶明亮, 邹汉法. AN AMINE CHEMISTRY METHOD FOR SELECTIVE ENRICHMENT OF N-LINKED GLYCOPEPTIDES FOR GLYCOPROTEOMICS ANALYSIS. 31st international symposium on microscale bioseparation. 2015, 第 4 作者http://cas-ir.dicp.ac.cn/handle/321008/143489.
[47] 姚亚婷, 黄俊峰, 程凯, 潘彦博, 秦洪强, 叶明亮, 邹汉法. Specific Enrichment of Peptides with N‑Terminal Serine/Threonine by a Solid-Phase Capture-Release Approach for Efficient Proteomics Analysis. ANALYTICAL CHEMISTRY[J]. 2015, 第 5 作者87: 11353, http://cas-ir.dicp.ac.cn/handle/321008/147819.
[48] Zhang, Zhang, Sun, Deguang, Cong, Yuting, Mao, Jiawei, Huang, Junfeng, Qin, Hongqiang, Liu, Jing, Huang, Guang, Wang, Liming, Ye, Mingliang, Zou, Hanfa. Amine Chemistry Method for Selective Enrichment of N-Linked Glycopeptides for Glycoproteomics Analysis. JOURNAL OF PROTEOME RESEARCH[J]. 2015, 第 6 作者14(9): 3892-3899, http://cas-ir.dicp.ac.cn/handle/321008/146549.
[49] 李瑞宾, ZhaoxiaJi, 秦洪强, XuedongKang, BingbingSun, MeiyingWang, ChongHyunChang, XiangWang, HaiyuanZhang, 邹汉法, AndreENel, TianXia. Interference in Autophagosome Fusion by Rare Earth Nanoparticles Disrupts Autophagic Flux and Regulation of an Interleukin-1β Producing Inflammasome. ACS NANO[J]. 2014, 第 3 作者8(10): 10280, http://cas-ir.dicp.ac.cn/handle/321008/144329.
[50] Huang, Guang, Sun, Zhen, Qin, Hongqiang, Zhao, Liang, Xiong, Zhichao, Peng, Xiaojun, Ou, Junjie, Zou, Hanfa. Preparation of hydrazine functionalized polymer brushes hybrid magnetic nanoparticles for highly specific enrichment of glycopeptides. ANALYST[J]. 2014, 第 3 作者139(9): 2199-2206, http://www.irgrid.ac.cn/handle/1471x/858830.
[51] Li, Ruibin, Ji, Zhaoxia, Qin, Hongqiang, Kang, Xuedong, Sun, Bingbing, Wang, Meiying, Chang, Chong Hyun, Wang, Xiang, Zhang, Haiyuan, Zou, Hanfa, Nel, Andre E, Xia, Tian. Interference in Autophagosome Fusion by Rare Earth Nanoparticles Disrupts Autophagic Flux and Regulation of an Interleukin-1 beta Producing Inflammasome. ACS NANO[J]. 2014, 第 3 作者8(10): 10280-10292, http://dx.doi.org/10.1021/nn505002w.
[52] Huang, Junfeng, Qin, Hongqiang, Dong, Jing, Song, Chunxia, Bian, Yangyang, Dong, Mingming, Cheng, Kai, Wang, Fangjun, Sun, Deguang, Wang, Liming, Ye, Mingliang, Zou, Hanfa. In Situ Sample Processing Approach (iSPA) for Comprehensive Quantitative Phosphoproteome Analysis. JOURNAL OF PROTEOME RESEARCH[J]. 2014, 第 2 作者13(9): 3896-3904, http://cas-ir.dicp.ac.cn/handle/321008/144524.
[53] 秦洪强, 黄俊峰, 孙珍, 王方军, 叶明亮, 邹汉法. 原位富集-选择性标记技术用于蛋白质翻译后修饰的定量分析. The 5th Asia Oceania Mass Spectrometry Conference & The 33rd Chinese Mass Spectrometry Society Annual Conference. 2014, 第 1 作者http://cas-ir.dicp.ac.cn/handle/321008/143594.
[54] Liu, Jing, Wang, Fangjun, Zhu, Jun, Mao, Jiawei, Liu, Zheyi, Cheng, Kai, Qin, Hongqiang, Zou, Hanfa. Highly efficient N-glycoproteomic sample preparation by combining C-18 and graphitized carbon adsorbents. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2014, 第 7 作者406(13): 3103-3109, http://cas-ir.dicp.ac.cn/handle/321008/145575.
[55] Dong, Mingming, Ye, Mingliang, Cheng, Kai, Dong, Jing, Zhu, Jun, Qin, Hongqiang, Bian, Yangyang, Zou, Hanfa. Identification of phosphopeptides with unknown cleavage specificity by a de novo sequencing assisted database search strategy. PROTEOMICS[J]. 2014, 第 6 作者14(21-22): 2410-2416, http://cas-ir.dicp.ac.cn/handle/321008/144419.
[56] Deng, Zhenzhen, Ye, Mingliang, Bian, Yangyang, Liu, Zheyi, Liu, Fangjie, Wang, Chunli, Qin, Hongqiang, Zou, Hanfa. Multiplex isotope dimethyl labeling of substrate peptides for high throughput kinase activity assay via quantitative MALDI MS. CHEMICAL COMMUNICATIONS[J]. 2014, 第 7 作者50(90): 13960-13962, http://cas-ir.dicp.ac.cn/handle/321008/144507.
[57] Huang, Guang, Xiong, Zhichao, Qin, Hongqiang, Zhu, Jun, Sun, Zhen, Zhang, Yi, Peng, Xiaojun, Ou, Junjie, Zou, Hanfa. Synthesis of zwitterionic polymer brushes hybrid silica nanoparticles via controlled polymerization for highly efficient enrichment of glycopeptides. ANALYTICA CHIMICA ACTA[J]. 2014, 第 3 作者809: 61-68, http://dx.doi.org/10.1016/j.aca.2013.11.049.
[58] Wu, Yue, Wang, Fangjun, Liu, Zheyi, Qin, Hongqiang, Song, Chunxia, Huang, Junfeng, Bian, Yangyang, Wei, Xiaoluan, Dong, Jing, Zou, Hanfa. Five-plex isotope dimethyl labeling for quantitative proteomics. CHEMICAL COMMUNICATIONS[J]. 2014, 第 4 作者50(14): 1708-1710, http://cas-ir.dicp.ac.cn/handle/321008/143851.
[59] Li, Ruibin, Wu, Renan, Zhao, Liang, Qin, Hongqiang, Wu, Jianlin, Zhang, Jingwen, Bao, Ruyi, Zou, Hanfa. In vivo detection of magnetic labeled oxidized multi-walled carbon nanotubes by magnetic resonance imaging. NANOTECHNOLOGY[J]. 2014, 第 4 作者25(49): http://cas-ir.dicp.ac.cn/handle/321008/145725.
[60] Fang, Chunli, Xiong, Zhichao, Qin, Hongqiang, Huang, Guang, Liu, Jing, Ye, Mingliang, Feng, Shun, Zou, Hanfa. One-pot synthesis of magnetic colloidal nanocrystal clusters coated with chitosan for selective enrichment of glycopeptides. ANALYTICA CHIMICA ACTA[J]. 2014, 第 3 作者841: 99-105, http://dx.doi.org/10.1016/j.aca.2014.05.037.
[61] Chen, Guifu, Wang, Feng, Wang, Yehong, Zhang, Xiaochen, Qin, Hongqiang, Zou, Hanfa, Xu, Jie. Imine-linked conjugated organic polymer bearing bis(imino)pyridine ligands and its catalytic application in C-C coupling reactions. CHINESE JOURNAL OF CATALYSIS[J]. 2014, 第 5 作者35(4): 540-545, http://dx.doi.org/10.1016/S1872-2067(14)60021-8.
[62] Chen Guifu, Wang Feng, Wang Yehong, Zhang Xiaochen, Qin Hongqiang, Zou Hanfa, Xu Jie. 一种嵌有双亚胺基吡啶配体的全共轭有机聚合物材料及其在C-C偶联反应中的应用. 催化学报[J]. 2014, 第 5 作者35(4): 540-545, http://lib.cqvip.com/Qikan/Article/Detail?id=49148613.
[63] 陈贵夫, 王峰, 王业红, 张晓辰, 秦洪强, 邹汉法, 徐杰. 一种嵌有双亚胺基吡啶配体的全共轭有机聚合物材料及其在C-C偶联反应中的应用. 催化学报[J]. 2014, 第 5 作者35(4): 540-545, http://lib.cqvip.com/Qikan/Article/Detail?id=49148613.
[64] Pan, Yanbo, Ye, Mingliang, Zheng, Hao, Cheng, Kai, Sun, Zhen, Liu, Fangjie, Liu, Jing, Wang, Keyun, Qin, Hongqiang, Zou, Hanfa. Trypsin-Catalyzed N-Terminal Labeling of Peptides with Stable Isotope-Coded Affinity Tags for Proteome Analysis. ANALYTICALCHEMISTRY[J]. 2014, 第 9 作者86(2): 1170-1177, http://cas-ir.dicp.ac.cn/handle/321008/145495.
[65] 邹汉法, 王方军, 叶明亮, 朱俊, 孙珍, 秦洪强, 黄俊峰. Solid-phase based technologies and methods for glycoproteome and phsophoproteome analysis. 39TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS. 2013, 第 6 作者34, http://159.226.238.44/handle/321008/116938.
[66] 张轶, 胡争艳, 秦洪强, 卫晓鸾, 程凯, 刘芳洁, 吴仁安, 邹汉法. Highly Efficient Extraction of the Cellular Nucleic Acid Associated Protein in Vitro with Magnetic Oxidized Carbon Nanotube. 39TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS. 2013, 第 3 作者119, http://159.226.238.44/handle/321008/116937.
[67] Liu, Fangjie, Ye, Mingliang, Wang, Chunli, Hu, Zhengyan, Zhang, Yi, Qin, Hongqiang, Cheng, Kai, Zou, Hanfa. Polyacrylamide Gel with Switchable Trypsin Activity for Analysis of Proteins. ANALYTICAL CHEMISTRY[J]. 2013, 第 6 作者85(15): 7024-7028, http://www.irgrid.ac.cn/handle/1471x/720995.
[68] Qin, Hongqiang, Hu, Zhengyan, Wang, Fangjun, Zhang, Yi, Zhao, Liang, Xu, Guiju, Wu, Renan, Zou, Hanfa. Facile preparation of ordered mesoporous silica-carbon composite nanoparticles for glycan enrichment. CHEMICAL COMMUNICATIONS[J]. 2013, 第 1 作者49(45): 5162-5164, http://www.irgrid.ac.cn/handle/1471x/721074.
[69] Xu, Bo, Chen, Chen, Wang, Fangjun, Bian, Yangyang, Cheng, Kai, Qin, Hongqiang, Song, Chunxia, Zhu, Jun, Liu, Jing, Ye, Mingliang, Zou, Hanfa. High specific phosphopeptides enrichment by titanium silicalite with post-treatment of desilication. ANALYTICAL METHODS[J]. 2013, 第 6 作者5(12): 2939-2946, http://www.irgrid.ac.cn/handle/1471x/721029.
[70] Xiong, Zhichao, Qin, Hongqiang, Wan, Hao, Huang, Guang, Zhang, Zhang, Dong, Jing, Zhang, Lingyi, Zhang, Weibing, Zou, Hanfa. Layer-by-layer assembly of multilayer polysaccharide coated magnetic nanoparticles for the selective enrichment of glycopeptides. CHEMICALCOMMUNICATIONS[J]. 2013, 第 2 作者49(81): 9284-9286, http://www.irgrid.ac.cn/handle/1471x/858638.
[71] Wan, Hao, Qin, Hongqiang, Xiong, Zhichao, Zhang, Weibing, Zou, Hanfa. Facile synthesis of yolk-shell magnetic mesoporous carbon microspheres for efficient enrichment of low abundance peptides. NANOSCALE[J]. 2013, 第 2 作者5(22): 10936-10944, http://159.226.238.44/handle/321008/119175.
[72] Zhu, Jun, Wang, Fangjun, Cheng, Kai, Song, Chunxia, Qin, Hongqiang, Hu, Lianghai, Figeys, Daniel, Ye, Mingliang, Zou, Hanfa. Analysis of human serum phosphopeptidome by a focused database searching strategy. JOURNAL OF PROTEOMICS[J]. 2013, 第 5 作者78: 389-397, http://dx.doi.org/10.1016/j.jprot.2012.10.006.
[73] 邹汉法, 秦洪强, 王方军, 吴仁安. Highly efficient extraction of biological samples with mesoporous adsorbents for protein and peptides analysis. the 5th international symposium on microchemistry and microsystems. 2013, 第 2 作者10, http://159.226.238.44/handle/321008/120178.
[74] 徐博, 周丽萍, 王方军, 秦洪强, 朱俊, 邹汉法. Selective capture of phosphopeptides by the hierarchical Ti-aluminophosphate-5 molecular sieves. the 5th international symposium on microchemistry and microsystems. 2013, 第 4 作者18, http://159.226.238.44/handle/321008/120176.
[75] 胡争艳, 张轶, 赵樑, 秦洪强, 吴仁安, 邹汉法. Highly Efficient Cleavage of Protein Corona on Fe3O4 Nanoparticles by a Magnetic Tryptic Nanorazor. the 5th international symposium on microchemistry and microsystems. 2013, 第 4 作者19, http://159.226.238.44/handle/321008/120174.
[76] Bian, Yangyang, Ye, Mingliang, Wang, Chunli, Cheng, Kai, Song, Chunxia, Dong, Mingming, Pan, Yanbo, Qin, Hongqiang, Zou, Hanfa. Global Screening of CK2 Kinase Substrates by an Integrated Phosphoproteomics Workflow. SCIENTIFIC REPORTS[J]. 2013, 第 8 作者3: http://www.irgrid.ac.cn/handle/1471x/858648.
[77] 宋春侠, 孙珍, 秦洪强, 叶明亮, 张丽华, 张玉奎, 邹汉法. 修饰蛋白质组学分离鉴定新技术新方法. 科学通报[J]. 2013, 第 3 作者58(30): 1, http://159.226.238.44/handle/321008/119541.
[78] Wang, Fangjun, Cheng, Kai, Wei, Xiaoluan, Qin, Hongqiang, Chen, Rui, Liu, Jing, Zou, Hanfa. A six-plex proteome quantification strategy reveals the dynamics of protein turnover. SCIENTIFIC REPORTS[J]. 2013, 第 4 作者3: http://www.irgrid.ac.cn/handle/1471x/721015.
[79] Pan, Yanbo, Ye, Mingliang, Zhao, Liang, Cheng, Kai, Dong, Mingming, Song, Chunxia, Qin, Hongqiang, Wang, Fangjun, Zou, Hanfa. N-Terminal Labeling of Peptides by Trypsin-Catalyzed Ligation for Quantitative Proteomics. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2013, 第 7 作者52(35): 9205-9209, http://www.irgrid.ac.cn/handle/1471x/720966.
[80] Zhang, Yi, Hu, Zhengyan, Qin, Hongqiang, Liu, Fangjie, Cheng, Kai, Wu, Renan, Zou, Hanfa. Cell Nucleus Targeting for Living Cell Extraction of Nucleic Acid Associated Proteins with Intracellular Nanoprobes of Magnetic Carbon Nanotubes. ANALYTICAL CHEMISTRY[J]. 2013, 第 3 作者85(15): 7038-7043, http://www.irgrid.ac.cn/handle/1471x/720971.
[81] Xiong, Zhichao, Zhao, Liang, Wang, Fangjun, Zhu, Jun, Qin, Hongqiang, Wu, Renan, Zhang, Weibing, Zou, Hanfa. Synthesis of branched PEG brushes hybrid hydrophilic magnetic nanoparticles for the selective enrichment of N-linked glycopeptides. CHEMICAL COMMUNICATIONS[J]. 2012, 第 5 作者48(65): 8138-8140, http://www.irgrid.ac.cn/handle/1471x/721275.
[82] 邹汉法, 秦洪强, 赵樑, 吴仁安. Highly Selective Extraction of Biological Samples with the Adsorbents of Mesoporous Materials. THE 27TH INTERNATIONAL SYMPOSIUM ON MICROSCALE BIOSEPARATIONS AND ANALYSES. 2012, 第 2 作者37, http://159.226.238.44/handle/321008/117234.
[83] Sun, Zhen, Chen, Rui, Cheng, Kai, Liu, Hongwei, Qin, Hongqiang, Ye, Mingliang, Zou, Hanfa. A new method for quantitative analysis of cell surface glycoproteome. PROTEOMICS[J]. 2012, 第 5 作者12(22): 3328-3337, http://www.irgrid.ac.cn/handle/1471x/721362.
[84] Qin, Hongqiang, Wang, Fangjun, Wang, Peiyuan, Zhao, Liang, Zhu, Jun, Yang, Qihua, Wu, Renan, Ye, Mingliang, Zou, Hanfa. Phosphoric acid functionalized mesoporous organo-silica (EPO) as the adsorbent for in situ enrichment and isotope labeling of endogenous phosphopeptides. CHEMICAL COMMUNICATIONS[J]. 2012, 第 1 作者48(7): 961-963, http://www.irgrid.ac.cn/handle/1471x/721703.
[85] 秦洪强, 王方军, 张轶, 胡争艳, 宋春侠, 吴仁安, 叶明亮, 邹汉法. Isobaric Cross-Sequence Labeling of Peptides by Using Site-Selective Dimethylation Reaction. 38TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2012, 第 1 作者120, http://159.226.238.44/handle/321008/117214.
[86] Zhao, Liang, Qin, Hongqiang, Hu, Zhengyan, Zhang, Yi, Wu, Renan, Zou, Hanfa. A poly(ethylene glycol)-brush decorated magnetic polymer for highly specific enrichment of phosphopeptides. CHEMICAL SCIENCE[J]. 2012, 第 2 作者3(9): 2828-2838, http://www.irgrid.ac.cn/handle/1471x/721719.
[87] Wang, Fangjun, Zhu, Jun, Hu, Lianghai, Qin, Hongqiang, Ye, Mingliang, Zou, Hanfa. Comprehensive analysis of the N and C terminus of endogenous serum peptides reveals a highly conserved cleavage site pattern derived from proteolytic enzymes. PROTEIN & CELL[J]. 2012, 第 4 作者3(9): 669-674, http://www.irgrid.ac.cn/handle/1471x/721441.
[88] Zhao, Liang, Qin, Hongqiang, Wu, Renan, Zou, Hanfa. Recent advances of mesoporous materials in sample preparation. JOURNAL OF CHROMATOGRAPHY A[J]. 2012, 第 2 作者1228: 193-204, http://dx.doi.org/10.1016/j.chroma.2011.09.051.
[89] Xu, Bo, Zhou, Lipeng, Wang, Fangjun, Qin, Hongqiang, Zhu, Jun, Zou, Hanfa. Selective capture of phosphopeptides by hierarchical Ti-aluminophosphate-5 molecular sieves. CHEMICAL COMMUNICATIONS[J]. 2012, 第 4 作者48(12): 1802-1804, http://www.irgrid.ac.cn/handle/1471x/721440.
[90] Zhang, Zhenbin, Lin, Hui, Ou, Junjie, Qin, Hongqiang, Wu, Renan, Dong, Jing, Zou, Hanfa. Preparation of phenyl-silica hybrid monolithic column with "one-pot" process for capillary liquid chromatography. JOURNAL OF CHROMATOGRAPHY A[J]. 2012, 第 4 作者1228: 263-269, http://dx.doi.org/10.1016/j.chroma.2011.07.048.
[91] Zhang, Yi, Hu, Zhengyan, Qin, Hongqiang, Wei, Xiaoluan, Cheng, Kai, Liu, Fangjie, Wu, Renan, Zou, Hanfa. Highly Efficient Extraction of Cellular Nucleic Acid Associated Proteins in Vitro with Magnetic Oxidized Carbon Nanotubes. ANALYTICAL CHEMISTRY[J]. 2012, 第 3 作者84(23): 10454-10462, http://www.irgrid.ac.cn/handle/1471x/721410.
[92] 秦洪强, 王方军, 张轶, 胡争艳, 宋春侠, 吴仁安, 叶明亮, 邹汉法. Isobaric Cross-Sequence Labeling of Peptides for Quantification of Proteins by MS/MS. ASIA OCEANIA HUMAN PROTEOME ORGANIZATION 6TH CONGRESS　. 2012, 第 1 作者232, http://159.226.238.44/handle/321008/116980.
[93] 徐博, ZhouLipeng, 王方军, 秦洪强, 朱俊, 邹汉法. Selective Capture of Phosphopeptides by the Hierarchical Tialuminophosphate-. ASIA OCEANIA HUMAN PROTEOME ORGANIZATION 6TH CONGRESS　. 2012, 第 4 作者295, http://159.226.238.44/handle/321008/116978.
[94] Sun, Zhen, Qin, Hongqiang, Wang, Fangjun, Cheng, Kai, Dong, Mingming, Ye, Mingliang, Zou, Hanfa. Capture and Dimethyl Labeling of Glycopeptides on Hydrazide Beads for Quantitative Glycoproteomics Analysis. ANALYTICAL CHEMISTRY[J]. 2012, 第 2 作者84(20): 8452-8456, http://www.irgrid.ac.cn/handle/1471x/721429.
[95] 邹汉法, 秦洪强, 王方军, 吴仁安. Size-selective Extraction of Biological Samples with Mesoporous Adsorbents for Protein and Peptides Analysis. 19TH INTERNATIONAL SYMPOSIUM EXHIBIT & WORKSHOPS ON ELECTRO- AND LIQUID PHASE-SEPARATION TECHNIQUES. 2012, 第 2 作者6, http://159.226.238.44/handle/321008/117144.
[96] Qin, Hongqiang, Wang, Fangjun, Zhang, Yi, Hu, Zhengyan, Song, Chunxia, Wu, Renan, Ye, Mingliang, Zou, Hanfa. Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation. CHEMICAL COMMUNICATIONS[J]. 2012, 第 1 作者48(50): 6265-6267, http://www.irgrid.ac.cn/handle/1471x/721369.
[97] Zhang, Zhenbin, Wang, Fangjun, Xu, Bo, Qin, Hongqiang, Ye, Mingliang, Zou, Hanfa. Preparation of capillary hybrid monolithic column with sulfonate strong cation exchanger for proteome analysis. JOURNAL OF CHROMATOGRAPHY A[J]. 2012, 第 4 作者1256: 136-143, http://dx.doi.org/10.1016/j.chroma.2012.07.071.
[98] 吴仁安, 张宇, 秦洪强, 闵乾昊, 邹汉法. Mesoporous Materials for Sample Preparation in Bioanalysis. JONIT CONGRESS 2011 FINAL PROGRAM. 2011, 第 3 作者37-0, http://159.226.238.44/handle/321008/115945.
[99] 吴仁安, 张宇, 秦洪强, 闵乾昊, 邹汉法. Mesoporous Materials for Sample Preparation in Bioanalysis. 26TH INTERNATIONAL SYMPOSIUM ON MICROSCALE BIOSEPARATIONS. 2011, 第 3 作者37, http://159.226.238.44/handle/321008/117465.
[100] Qin, Hongqiang, Zhao, Liang, Li, Ruibin, Wu, Renan, Zou, Hanfa. Size-Selective Enrichment of N-Linked Glycans Using Highly Ordered Mesoporous Carbon Material and Detection by MALDI-TOF MS. ANALYTICAL CHEMISTRY[J]. 2011, 第 1 作者83(20): 7721-7728, http://www.irgrid.ac.cn/handle/1471x/456645.
[101] Qin, Hongqiang, Gao, Peng, Wang, Fangjun, Zhao, Liang, Zhu, Jun, Wang, Aiqin, Zhang, Tao, Wu, Renan, Zou, Hanfa. Highly Efficient Extraction of Serum Peptides by Ordered Mesoporous Carbon. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2011, 第 1 作者50(51): 12218-12221, http://www.irgrid.ac.cn/handle/1471x/457107.
[102] 王方军, 徐博, 秦洪强, 邹汉法. Solid-phase isotope labeling and multidimensional separation for proteome and phosphoproteome quantification. 37TH INTERNATIONAL SYMPOSIUM ON HIGH-PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 3 作者138, http://159.226.238.44/handle/321008/117422.
[103] Wu, Minghuo, Wu, Renan, Li, Ruibing, Qin, Hongqiang, Dong, Jing, Zhang, Zhenbin, Zou, Hanfa. Polyhedral Oligomeric Silsesquioxane as a Cross-linker for Preparation of Inorganic-Organic Hybrid Monolithic Columns. ANALYTICAL CHEMISTRY[J]. 2010, 第 4 作者82(13): 5447-5454, http://159.226.238.44/handle/321008/103143.
[104] 张宇, 秦洪强, 吴仁安, 邹汉法. Ti-SBA-15介孔材料用于磷酸化肽的高效富集. 色谱[J]. 2010, 第 2 作者28(2): 123-127, http://lib.cqvip.com/Qikan/Article/Detail?id=33012691.
[105] Min, Qianhao, Wu, Renan, Zhao, Liang, Qin, Hongqiang, Ye, Mingliang, Zhu, JunJie, Zou, Hanfa. Size-selective proteolysis on mesoporous silica-based trypsin nanoreactor for low-MW proteome analysis. CHEMICAL COMMUNICATIONS[J]. 2010, 第 4 作者46(33): 6144-6146, http://159.226.238.44/handle/321008/103187.
[106] Dong, Mingming, Wu, Minghuo, Wang, Fangjun, Qin, Hongqiang, Han, Guanghui, Gong, Jing, Wu, Renan, Ye, Mingliang, Liu, Zhen, Zou, Hanfa. Coupling Strong Anion-Exchange Monolithic Capillary with MALDI-TOF MS for Sensitive Detection of Phosphopeptides in Protein Digest. ANALYTICAL CHEMISTRY[J]. 2010, 第 4 作者82(7): 2907-2915, http://dx.doi.org/10.1021/ac902907w.
[107] Zhang, Yu, Chen, Chen, Qin, Hongqiang, Wu, Renan, Zou, Hanfa. The synthesis of Ti-hexagonal mesoporous silica for selective capture of phosphopeptides. CHEMICAL COMMUNICATIONS[J]. 2010, 第 3 作者46(13): 2271-2273, http://159.226.238.44/handle/321008/103055.
[108] 秦洪强, 吴仁安, 潘陈松, 陈锐, 赵梁, 邹汉法. Profiling of N-linked Glycans from Human Serum with Oxidative Ordered Mesoporous Carbon. the 24th international symposium on micro-scale bioseparation,. 2009, 第 1 作者264/1, http://159.226.238.44/handle/321008/113854.
[109] 董铭铭, 吴明火, 王方军, 秦洪强, 韩广辉, 董靖, 吴仁安, 叶明亮, 刘震, 邹汉法. Enrichment of Phosphopeptides by a Novel SAX Capillary Monolithic Column for Sensitive MALDI-TOF MS Analysis. the 24th international symposium on micro-scale bioseparation,. 2009, 第 4 作者259/1, http://159.226.238.44/handle/321008/113840.

   

（ 1 ） 血清内源性多肽定量分析方法的建立及其用于抑郁症疾病标记物的筛, 负责人, 国家任务, 2015-01--2017-12
（ 2 ） 蛋白糖基化修饰在胃癌多药耐药中特征性改变及其作用机制研究, 负责人, 国家任务, 2015-01--2018-12
（ 3 ） 基于非天然糖代谢标记的分泌蛋白质糖基化精细分析新方法研究, 负责人, 国家任务, 2018-01--2021-12
（ 4 ） 人类蛋白质组计划2.0-蛋白质组学驱动的精准 医学计划, 参与, 国家任务, 2020-12--2023-12

第四军医大学、大连医科大学、大连理工大学等单位

现指导学生

周家华  博士研究生  070302-分析化学  

刘莉  硕士研究生  070302-分析化学  

王佳怡  硕士研究生  070302-分析化学  

陈尧  博士研究生  070302-分析化学