General
邓馨 女 汉族 博导 植物研究所
Email: deng@ibcas.ac.cn
Telephone: 62836261
Mobile phone:
Address: Institute of Botany, Chinese Academy of Sciences
Postcode: 100093

Research Areas

1. The molecular mechanisms of plant desiccation resistance;
2. Hormone regulation of plant growth and development in stress conditions;

3. Epigenetic regulation of plant stress memory.


     Drought stress severely affects plant growth and development. Resurrection plants have evolved a unique set of adaptive mechanisms to tolerate water loss of more than 95% and recover rapidly after rehydration. To reveal the bases of their adaptation, we have launched comprehensive omics studies on the resurrection plants Boea hygrometrica, aiming to identify the key components that play important roles for the protection and repair during dehydration and resurrection process. Special attention is paid to the genes that are involved in signal transduction, hormone regulation, stomata movement and osmo-regulation, as well as the epigenetic regulation of plant stress memory. 

Education

Dr. Deng received her bachelor's degree in Heilongjiang Bayi Agricultural University in 1993, master's degree in Shenyang Agricultural University in 1996, and her Ph.D. degree in Institute of Botany, Chinese Academy of Sciences in 1999.

Experience

From1999 to 2003, she worked on desiccation tolerance of resurrection plants in Max Planck Institute for Plant Breeding Research as a postdoctoral researcher. 
As a visiting scholar, she visited University of Bonn, Germany in 2005 and UC Riverside, United States in 2009 and 2010 and established collaboration on the project of plant stress molecular mechanisms.
Work Experience
In 2003, she started her career in IBCAS. She became a professor since 2009 and the leader of Plant Desiccation tolerance Group since 2008.

Honors & Distinctions

In 2006, she was elected to Novel Stars of Science and Technology supported by Beijing Metropolis.

Publications

  1. DNA methylation-mediated modulation of rapid desiccation tolerance acquisition and dehydration stress memory in the resurrection plant Boea hygrometrica, PLOS GENETICS, 2021

  2. A role of age-dependent DNA methylation reprogramming in regulating the regeneration capacity of Boea hygrometrica leaves, FUNCTIONAL & INTEGRATIVE GENOMICS, 2020

  3. Common and Specific Mechanisms of Desiccation Tolerance in Two Gesneriaceae Resurrection Plants. Multiomics Evidences, FRONTIERS IN PLANT SCIENCE, 2019

  4. Single-Molecule Imaging and Computational Microscopy Approaches Clarify the Mechanism of the Dimerization and Membrane Interactions of Green Fluorescent Protein, International Journal of Molecular Sciences, 2019

  5. Weighted Gene Co-expression Network Analysis (WGCNA) Reveals the Hub Role of Protein Ubiquitination in the Acquisition of Desiccation Tolerance in Boea hygrometrica, PLANT AND CELL PHYSIOLOGY, 2019

  6. Transcriptome reprogramming during severe dehydration contributes to physiological and metabolic changes in the resurrection plant Haberlea rhodopensis, BMC PLANT BIOLOGY, 2018

  7. Arabidopsis Blue Light Receptor Phototropin 1 Undergoes Blue Light-Induced Activation in Membrane Microdomains, MOLECULAR PLANT, 2018

  8. Acclimation-induced metabolic reprogramming contributes to rapid desiccation tolerance acquisition in Boea hygrometrica, ENVIRONMENTAL AND EXPERIMENTAL BOTANY, 2018

  9. BhbZIP60 from Resurrection Plant Boea hygrometrica Is an mRNA Splicing-Activated Endoplasmic Reticulum Stress Regulator Involved in Drought Tolerance, FRONTIERS IN PLANT SCIENCE, 2017

  10. A modified GFP facilitates counting membrane protein subunits by step-wise photobleaching in Arabidopsis, JOURNAL OF PLANT PHYSIOLOGY, 2017

  11. Arabidopsis seed germination speed is controlled by SNL histone deacetylase-binding factor-mediated regulation of AUX1, NATURE COMMUNICATIONS, 2016

  12. An Effective and Inducible System of TAL Effector-Mediated Transcriptional Repression in Arabidopsis, MOLECULAR PLANT, 2016

  13. Transcriptome and Degradome Sequencing Reveals Dormancy Mechanisms of Cunninghamia lanceolata Seeds, PLANT PHYSIOLOGY, 2016

  14. ABA receptor PYL9 promotes drought resistance and leaf senescence, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016

  15. RDM4 modulates cold stress resistance in Arabidopsis partially through the CBF-mediated pathway, NEW PHYTOLOGIST, 2016

  16. An Effective and Inducible System of TAL Effector-Mediated Transcriptional Repression in Arabidopsis, An Effective and Inducible System of TAL Effector-Mediated Transcriptional Repression in Arabidopsis, Molecular Plant, 2015

  17. The resurrection genome of Boea hygrometrica : A blueprint for survival of dehydration, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015

  18. Microrna857 is involved in the regulation of secondary growth of vascular tissues in arabidopsis, PLANT PHYSIOLOGY, 2015

  19. Single-molecule fluorescence imaging to quantify membrane protein dynamics and oligomerization in living plant cells, NATURE PROTOCOLS, 2015

  20. Global transcriptome analysis reveals acclimation-primed processes involved in the acquisition of desiccation tolerance in boea hygrometrica, PLANT AND CELL PHYSIOLOGY, 2015

  21. A comparative study on Ca content and distribution in two Gesneriaceae species reveals distinctive mechanisms to cope with high rhizospheric soluble calcium, FRONTIERS IN PLANT SCIENCE, 2014

  22. Identification of a retroelement from the resurrection plant boea hygrometrica that confers osmotic and alkaline tolerance in arabidopsis thaliana., PLOS ONE, 2014

  23. A 30-kb genomic DNA fragment of resurrection plant Boea hygrometrica enhances Arabidopsis osmotic and alkaline tolerance, Journal of Food, Agriculture & Environment, 2014

  24. Identification of Quantitative Trait Loci Controlling High Calcium Response in Arabidopsis thaliana, PLOS ONE, 2014

  25. Molecular cloning and differential expression of sHSP gene family members from the resurrection plant Boea hygrometrica in response to abiotic stresses, BIOLOGIA, 2013

  26. Understanding desiccation tolerance using the resurrection plant Boea hygrometrica as a model system, FRONTIERS IN PLANT SCIENCE, 2013

  27.  Maize membrane-bound transcription factor zmbzip17 is a key regulator in the crosstalk of er quality control and aba signaling, PLANT AND CELL PHYSIOLOGY, 2013

  28. Arabidopsis paired amphipathic helix proteins snl1and snl2 redundantly regulate primary seed dormancy via abscisic acid–ethylene antagonism mediated by histone deacetylation, PLANT CELL, 2013

  29. The Complete Chloroplast and Mitochondrial Genome Sequences of Boea hygrometrica : Insights into the Evolution of Plant Organellar Genomes, PLOS ONE, 2012

  30. Comparative Study on the Expression of Genes Involved in Carotenoid and ABA Biosynthetic Pathway in Response to Salt Stress in Tomato, JOURNAL OF INTEGRATIVE AGRICULTURE, 2012

  31. A novel role for histone methyltransferase KYP/SUVH4 in the control of Arabidopsis primary seed dormancy, NEW PHYTOLOGIST, 2012

  32. An atypical component of RNA-directed DNA methylation machinery has both DNA methylation-dependent and -independent roles in locus-specific transcriptional gene silencing, CELL RESEARCH, 2011

  33. LEA 4 group genes from the resurrection plant Boea hygrometrica confer dehydration tolerance in transgenic tobacco, PLANT SCIENCE, 2009

  34. A WRKY transcription factor participates in dehydration tolerance in Boea hygrometrica by binding to the W-box elements of the galactinol synthase (BhGolS1) promoter, PLANTA, 2009

  35. Cloning and expression analysis of a dirigent protein gene from the resurrection plant Boea hygrometrica, PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL, 2009

  36. A role for a cell wall localized glycine-rich protein in dehydration and rehydration of the resurrection plant Boea hygrometrica, PLANT BIOLOGY, 2009

  37.  Ectopic over-expression of BhHsf1, a heat shock factor from the resurrection plant Boea hygrometrica, leads to increased thermotolerance and retarded growth in transgenic Arabidopsis and tobacco, PLANT MOLECULAR BIOLOGY, 2009

  38. A protein extraction method compatible with proteomic analysis for the euhalophyte Salicornia europaea, ELECTROPHORESIS, 2007

  39. Proteome analysis of leaves from the resurrection plant Boea hygrometrica in response to dehydration and rehydration, PLANTA, 2007

  40. Characterization and expression of beta-1,3-glucanase genes in jujube fruit induced by the microbial biocontrol agent cryptococcus laurentii, PHYTOPATHOLOGY, 2007

  41. A homeodomain leucine zipper gene from Craterostigma plantagineum regulates abscisic acid responsive gene expression and physiological responses, PLANT MOLECULAR BIOLOGY, 2006

  42. Changes in Photosynthetic Functions of a Resurrection Angiosperm Boea hygrometrica (Bunge) R.Br. (Gesneriaceae) during dessication and rehydration, Plant Sci, 2003

  43. Characterization of five novel dehydration-responsive homeodomain leucine zipper genes from the resurrection plant Craterostigma plantagineum, PLANT MOLECULAR BIOLOGY, 2002

  44. mRNA differential display visualized by silver staining tested on gene expression in resurrection plant Boea hygrometrica, PLANT MOLECULAR BIOLOGY REPORTER, 1999


Papers
  1. Zhao Y§, Chan Z§, Gao J, Xing L, Cao M, Yu C, Hu Y, You J, Shi H, Zhu Y, Gong Y, Mu Z, Wang H, Deng X, Wang P, Bressan RA, Zhu JK* (2016) The ABA receptor PYL9 promotes drought resistance and leaf senescence. Proc Natl Acad Sci U S A, doi:10.1073/pnas.1522840113.
  2. Xiao, Lihong; Yang, Ge; Zhang, Liechi; Yang, Xinhua; Zhao, Shuang; Ji, Zhongzhong; Zhou, Qing; Hu, Min; Wang, Yu; Chen, Ming; Xu, Yu; Jin, Haijing; Xiao, Xuan; Hu, Guipeng; Bao, Fang; Hu, Yong; Wan, Ping; Li, Legong; Deng, Xin; Kuang, Tingyun; Xiang, Chengbin; Zhu, Jian-Kang*; Oliver, Melvin J.*; He, Yikun* (2015) The resurrection genome of Boea hygrometrica: A blueprint for survival of dehydration. Proc Natl Acad Sci U S A. 112(18):5833-5837
  3. Yan Zhu; Bo Wang; Jonathan Phillips; Zhen-Nan Zhang; Hong Du; Tao Xu; Lian-Cheng Huang; Xiao-Fei Zhang; Guang-Hui Xu; Wen-Long Li; Zhi Wang; Ling Wang; Yong-Xiu Liu; Xin Deng* (2015) Global transcriptome analysis reveals acclimation-primed processes involved in the acquisition of desiccation tolerance in Boea hygrometrica. Plant Cell Physiol 56(7):1429-41 
  4. W Li, F Xu, S Chen, Z Zhang, Y Zhao, Y Jin, M Li, Y Zhu, Y Liu, Y Yang and Xin Deng* (2014) A comparative study on Ca content and distribution in two Gesneriaceae species reveals distinctive mechanisms to cope with high rhizospheric soluble calcium. Front Plant Sci 5: 647. doi: 10.3389/fpls.2014.00647  
  5. Yan Zhao, Tao Xu, Chun-Ying Shen, Guang-Hui Xu, Shi-Xuan Chen, Li-Zhen Song, Mei-Jing Li, Li-Li Wang, Yan Zhu, Wei-tao Lv, Zhi-Zhong Gong, Chun-Ming Liu, Xin Deng* (2014) Identification of a retroelement from the resurrection plant Boea hygrometrica that confers osmotic and alkaline tolerance in Arabidopsis thaliana. PLoS ONE 9(5): e98098. doi:10.1371/journal.pone.0098098.
  6. Wenlong Li, Huikun Duan, Fengying Chen, Zhi Wang, Xueqing Huang, Xin Deng, Yongxiu Liu* (2014) Identification of Quantitative Trait Loci Controlling High Calcium Response in Arabidopsis thaliana. PLoS ONE 9(11): e112511.
  7. Zhi Wang, Hong Cao, Yongzhen Sun, Xiaoying Li, Fengying Chen, Annaick Carles, Yong Li, Meng Ding, Cun Zhang, Xin Deng, Wim J.J. Soppe, Yong-Xiu Liu* (2013) Arabidopsis paired amphipathic helix proteins SNL1and SNL2 redundantly regulate primary seed dormancy via abscisic acid-ethylene antagonism mediated by histone deacetylation. Plant Cell, 25:149-166.
  8. Yan-Ge Yang, Wei-Tao Lv, Mei-Jing Li, Bo Wang, Dong-Mei Sun*, Xin Deng* (2013). Maize membrane-bound transcription factor Zmbzip17 is a key regulator in the crosstalk of ER quality control and aba signaling. Plant Cell Physiol 54(12): 2020–2033
  9. J Mitra, G Xu, B Wang, M Li, Xin Deng* (2013) Understanding desiccation tolerance using the resurrection plant Boea hygrometrica as a model system. Front Plant Sci 4:446. doi: 10.3389/fpls.2013.00446
  10. Zhennan Zhang, Bo Wang, Dongmei Sun* , Xin Deng* (2013) Molecular cloning and differential expression of sHSP gene family members from the resurrection plant Boea hygrometrica in response to abiotic stresses. Biologia 68(4): 651-661. 
  11. Zheng J, Chen FY, Wang Z, Cao H, Li XY, Deng X, Soppe Wim JJ, Li Y and Liu YX*. 2012. A novel role for histone methyltransferase KYPSUVH4 in the control of Arabidopsis primary seed dormancy. New Phytol 193: 605–616.
  12. HK Duan, Y Zhu, WL Li, DD Qi, YX Liu, Xin Deng * (2012) Comparative study on the expression of genes involved in carotenoid and ABA biosynthetic pathway in response to salt stress in tomato. J Integr Agr (formally: Agricultural Sciences in China), 11(7): 1093-1102.
  13. Jun Liu, Ge Bai, Cuijun Zhang, Wei Chen, Jinxing Zhou, Suwei Zhang, Qing Chen, Xin Deng, Xin-Jian He *, Jian-Kang Zhu. An atypical component of RNA-directed DNA methylation machinery has both DNA methylation- dependent and -independent roles in locus-specific transcriptional gene silencing. Cell Res (2011) 21:1691-1700.
  14. Tongwu Zhang, Yongjun Fang, Xumin Wang, Xin Deng, Xiaowei Zhang, Songnian Hu, Jun Yu*. (2011) The complete chloroplast and mitochondrial genome sequences of Boea hygrometrica: insights into the evolution of plant organellar genomes. PLoS ONE 7(1): e30531. doi:10.1371/journal.pone.0030531
  15. Y Zhu, Z Wang, YJ Jing, LL Wang, X Liu; YX Liu, Xin Deng * (2009) Ectopic over-expression of BhHsf1, a heat shock factor from the resurrection plant Boea hygrometrica, leads to increased thermotolerance and retarded growth in transgenic Arabidopsis and tobacco. Plant Mol Biol, 71(4-5): 451-67
  16. Zhi Wang, Yan Zhu, Lili Wang, Xia Liu, Yongxiu Liu, Jonathan Phillips, Xin Deng* (2009) A WRKY transcription factor participates in dehydration tolerance in Boea hygrometrica by binding to the W-box elements of the galactinol synthase (BhGolS1) promoter. Planta, 230(6): 1155-1166
  17. Lili Wang, Haihong Shang, Yongxiu Liu, Maozhong Zheng, Renhua Wu, Jonathan Phillips, Dorothea Bartels, Xin Deng* (2009) A role for a cell wall localized glycine-rich protein in dehydration and rehydration of the resurrection plant Boea hygrometrica. Plant Biol,11(6): 837-848
  18. Xia Liu, Zhi Wang, Lili Wang, Renhua Wu, Jonathan Phillips, Xin Deng* (2009) LEA 4 group genes from the resurrection plant Boea hygrometrica confer dehydration tolerance in transgenic tobacco. Plant Sci, 176: 90–98.
  19. Renhua Wu, Lili Wang, Zhi Wang, Haihong Shang, Xia Liu, Yan Zhu, Dongdong Qi, Xin Deng* (2009) Cloning and expression analysis of a dirigent protein gene from the resurrection plant Boea hygrometrica, Prog Nat Sci: 193: 347-353.
  20. G Jiang, Z Wang, H Shang, W Yang, Z Hu, J Phillips, Xin Deng * (2007) Proteome analysis of leaves from the resurrection plant Boea hygrometrica in response to dehydration and rehydration. Planta, 225 (6): 1405-1420 
  21. Xuchu WangXiaofang LiXin DengHeping HanWuliang ShiYinxin Li* (2007) A protein extraction method compatible with proteomic analysis for euhalophyte Salicornia europaea. Electrophoresis, 28(21):3976-3987 
  22. Tian S., Yao H., Deng X., et al. (2007) Characterization and expression of ß-1, 3-glucanase genes in jujube fruit induced by biocontrol microbial agent. Phytopathology 97, 260-268
  23. Xin Deng, J Phillips, A Brautigam, P Engström, H Johannesson, P Ouwerkerk, I Ruberti, J Salinas, P Vera, R Iannacone, A Meijer, D Bartels (2006) A homeodomain leucine zipper gene from Craterostigma plantagineum regulates abscisic acid responsive gene expression and physiological responses. Plant Mol Biol 61(3): 469-489.
  24. Xin Deng, Z Hu, H Wang, X Wen, T Kuang (2003) Changes in Photosynthetic Functions of a Resurrection Angiosperm Boea hygrometrica (Bunge) R.Br. (Gesneriaceae) during dessication and rehydration. Plant Sci 165(4): 851-861.
  25. Xin Deng, J Phillips, A Meijer, F Salamini, D Bartels (2002) Characterization of five novel dehydration-responsive homeodomain leucine zipper genes from the resurrection plant Craterostigma plantagineum. Plant Mol Biol 49 (6): 601-610.
  26. Li Y, Hu Z, Zhang Q, Deng X, and Wang H (2000) Genetic variation in wild soybean (Glycine soja Sieb. & Zucc.) populations revealed with simple sequence repeat marders. Soybean genetics newsletter 27: 17
  27. Xin Deng, Z Hu, H Wang (1999) mRNA differential display visualized by silver staining tested on gene expression in resurrection plant Boea hygrometrica. Plant Mol Biol Rep 17: 279.  
  28. Zhang Q, Yun R, Hu Z-A, Zhong M, Deng X. (1999) Cloning and characterization of a molecu-lar marker associated with salt tolerance from soybean cultivars. Soybean Genetics Newsletter 26:14

Patents
[1] Deng Xin et al. The application of salt-related genes and their encoded proteins in Boea hygrometrica. China, ZL200510127881.4. 
[2] Deng Xin et al. The synthesis and application of inositol-galactosidase gene and its encoded protein: China, ZL200510112540.X. 
[3] Deng Xin et al. A protein and its coding gene that functions in plant drought tolerance: China,ZL200510127881.4
[4] Deng Xin et al. An HSF and its coding gene that functions in plant stress tolerance: China,200910078056.8 
[5] Deng Xin et al. A DNA fragment that regulates plant tolerance to osmotic and alkaline stress. China,201210135602.9
[6]. Deng Xin et al. BhHSP70-1 and its coding gene that improves plant drought tolerance: China, 201210581636.07. 
[7] Deng Xin et al. The application of ZmbZIP17 and its coding gene in improving plant stress tolerance: China,201310065802.6
[8] Deng Xin et al. An plant drought tolerance-related protein and its coding gene: China, 201310149496.4

Research Interests

Drought stress severely affects plant growth and development. Resurrection plants in the long process of evolution have developed a unique adaptation mechanism of tolerating water loss more than95% and recovering after rehydration. To reveal the mechanism of their adaptation, we launched a systematic set of studies about the Resurrection plants (Boea hygrometrica), aiming to indentify the important genes and proteins e analysis of during the drought- recovery process. We pay more attention to the function of genes relating to signal transduction pathways, hormones regulation, stomata regulation and permeability protection, targeting at identifying drought gene resources, create drought-resistant plant materials.

Collaboration

1.  Joint Project under the Bulgaria/China agreement on cooperation in science and technology:

Revealing mechanisms that prime or trigger desiccation tolerance reprograming in local resurrection plants to improve crops stress response


2. Joint Project under the South Africa/China agreement on cooperation in science and technology:

A systems biology-based study of the cell wall of the resurrection plant Boea hygrometrica in comparison with the non-desiccation tolerant Chirita heterotrichia using molecular genetics and high-throughput profiling methods.


3. Joint Project under the Bulgaria/China agreement on cooperation in science and technology:

A comparative study of the mechanisms of desiccation tolerance in Gesneriaceae resurrection plants in Bulgaria and China


Students

已指导学生

王智  01  19174  

刘霞  02  19181  

吴仁花  02  19181  

朱燕  01  19181  

姬飞腾  02  19181  

段会坤  02  19181  

张兰军  02  19181  

赵燕  01  19181  

李美静  02  19181  

徐广惠  02  19181  

李文龙  01  19181  

沈春颖  02  19181  

刘璐  02  19181  

现指导学生

许韬  01  19181  

杜红  01  19181  

张潇雅  02  19182  

马金英  02  19182  

靳松松  01  19182  

赵通  02  19182  

刘杨  01  19182