基本信息
刘成波  男  博导  中国科学院深圳先进技术研究院
电子邮件: cb.liu@siat.ac.cn
通信地址: 深圳市西丽大学城学苑大道1068号
邮政编码: 518055

研究领域

生物医学光学,光声成像

招生信息

博士生,硕士生

招生专业
081102-检测技术与自动化装置
081104-模式识别与智能系统
081101-控制理论与控制工程
招生方向
生物医学光学,光声成像,光学分子影像
组织光谱
生物光子学

教育背景

2009-10--2011-10   美国杜克大学   访问学者
2007-09--2012-11   西安交通大学   博士
2003-09--2007-07   西安交通大学   学士
学历

研究生

学位
博士研究生

工作经历

2020.12-至今,中国科学院深圳先进技术研究院,研究员

2015.12-2020.12,中国科学院深圳先进技术研究院,副研究员
2012.11-2015.11,中国科学院深圳先进技术研究院,助理研究员

工作简历
2020-12~现在, 中国科学院深圳先进技术研究院, 研究员
2015-12~2020-12,中国科学院深圳先进技术研究院, 副研究员
2012-11~2015-11,中国科学院深圳先进技术研究院, 助理研究员

专利与奖励

   
专利成果
( 1 ) 一种手持式光声成像探头, 发明, 2015, 第 2 作者, 专利号: CN103393407B
( 2 ) 简易手持式光声成像探头, 发明, 2015, 第 2 作者, 专利号: CN103393406B
( 3 ) 一种光声探头及光声成像系统, 发明, 2016, 第 1 作者, 专利号: CN201710046338.4
( 4 ) 一种二硫化钼纳米片的剥离制备方法及二硫化钼纳米片的应用, 发明, 2016, 第 2 作者, 专利号: CN201610930421.3
( 5 ) 一种光声成像用纳米复合造影剂及其制备方法, 发明, 2015, 第 3 作者, 专利号: CN201410797931.9
( 6 ) 一种光声显微成像系统, 发明, 2016, 第 3 作者, 专利号: CN201710078203.6
( 7 ) 一种暗场照明声学分辨率光声显微装置, 发明, 2016, 第 3 作者, 专利号: CN201511030810.2

出版信息

   
发表论文
(1) Design and synthesis of a ratiometric photoacoustic probe for in situ imaging of zinc Ions in deep tissue in vivo, Analytical Chemistry, 2020, 通讯作者
(2) A new deep learning method for image deblurring in optical microscopic systems, Journal of Biophotonics, 2020, 通讯作者
(3) A 1064 nm excitable semiconducting polymer nanoparticle for photoacoustic imaging of gliomas, Nanoscale, 2019, 通讯作者
(4) Multiscale Vascular Enhancement Filter Applied to In Vivo Morphologic and Functional Photoacoustic, IEEE Photonics Journal, 2019, 通讯作者
(5) Optical-resolution photoacoustic microscopy for monitoring vascular normalization during anti-angiogenic therapy, Photoacoustics, 2019, 通讯作者
(6) In vivo transrectal imaging of canine prostate with a sensitive and compact handheld transrectal array photoacoustic probe for early diagnosis of prostate cancer, Biomedical Optics Express, 2019, 第 1 作者
(7) Novel small molecular dye-loaded lipid nanoparticles with efficient near-infrared-II absorption for photoacoustic imaging and photothermal therapy of hepatocellular carcinoma, Biomaterials Science, 2019, 通讯作者
(8) The integrated high-resolution reflection-mode photoacoustic and fluorescence confocal microscopy, Photoacoustics, 2019, 第 1 作者
(9) Motion Correction in Optical Resolution Photoacoustic Microscopy, IEEE Transactions on Medical Imaging, 2019, 通讯作者
(10) High-Resolution 3D NIR-II Photoacoustic Imaging of Cerebral and Tumor Vasculatures Using Conjugated Polymer Nanoparticles as Contrast Agent, Advanced Materials, 2019, 通讯作者
(11) Ultrasmall hybrid protein-copper sulfide nanoparticles for targeted photoacoustic imaging of orthotopic hepatocellular carcinoma with high signal-to-noise ratio, Biomaterials Science, 2019, 通讯作者
(12) Quantitative analysis on in vivo tumor-microvascular images from optical-resolution photoacoustic microscopy, Journal of Biophotonics, 2019, 第 1 作者
(13) Lack of association between acupoint sensitization and microcirculatory structural changes in a mouse model of knee osteoarthritis: A pilot study, Journal of Biophotonics, 2019, 通讯作者
(14) Ce6-Modified Carbon Dots for Multimodal-Imaging-Guided and Single-NIR-Laser-Triggered Photothermal/Photodynamic Synergistic Cancer Therapy by Reduced Irradiation Power, ACS Applied Materials & Interfaces, 2019, 通讯作者
(15) In vivo theranostics with near-infrared-emitting carbon dots-highly efficient photothermal therapy based on passive targeting after intravenous administration, Light: Science & Application, 2018, 通讯作者
(16) Single-Layer MoS2 Nanosheets with Amplified Photoacoustic Effect for Highly Sensitive Photoacoustic Imaging of Orthotopic Brain Tumors, Advanced Functional Materials, 2016, 第 1 作者
(17) Advances in Imaging Techniques and Genetically Encoded Probes for Photoacoustic Imaging, Theranostics, 2016, 第 1 作者
(18) Indocyanine Green-Loaded Polydopamine-Iron Ions Coordination Nanoparticles for Photoacoustic/Magnetic Resonance Dual-Modal Imaging-Guided Photothermal Therapy, Nanoscale, 2016, 第 1 作者
(19) Indocyanine Green Loaded Reduced Graphene Oxide for In Vivo Photoacoustic/Fluorescence Dual-Modality Tumor Imaging, Nanoscale Research Letters, 2016, 通讯作者
(20) Functional Photoacoustic Imaging of Gastric Acid Secretion Using pH-Responsive Polyaniline Nanoprobes, Small, 2016, 第 4 作者
(21) Activatable albumin-photosensitizer nanoassemblies for triple-modal imaging and thermal-modulated photodynamic therapy of cancer, Biomaterials, 2016, 第 5 作者
(22) Advances in Imaging Techniques and Genetically Encoded Probes for Photoacoustic Imaging, Theranostics, 2016, 第 1 作者
(23) Dual-color photoacoustic lymph node imaging using nanoformulated naphthalocyanines, Biomaterials, 2015, 第 5 作者
(24) A Facile Synthesis of Versatile Cu2-xS Nanoprobe for Enhanced MRI and Infrared Thermal/Photoacoustic Multimodal Imaging, Biomaterials, 2015, 第 1 作者
(25) Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging, Nanoscale, 2015, 第 1 作者
(26) Ultrasmall Cu2-xS Nanodots for Highly Efficient Photoacoustic Imaging-Guided Photothermal Therapy, Small, 2015, 第 3 作者
(27) High-speed intravascular spectroscopic photoacoustic imaging at 1000 A-lines per second with a 0.9 mm diameter catheter, Journal of Biomedical Optics, 2015, 第 3 作者
(28) In vivo photoacoustic molecular imaging of breast carcinoma with folate receptor-targeted indocyanine green nanoprobes, Nanoscale, 2014, 第 1 作者
(29) India ink incorporated multifunctional phase-transition nanaodroplets for photoacoustic/ultrasound dual-modality imaging and photoacoustic effect based tumor therapy, Theranostics, 2014, 第 2 作者
(30) Compressed sensing based virtual-detector photoacoustic microscopy in vivo, Journal of Biomedical Optics, 2014, 第 2 作者
(31) Intravascular optical-resolution photoacoustic microscopy with a 1.1 mm diameter catheter, PLOS ONE, 2014, 第 5 作者
(32) Experimental Validation of an Inverse Fluorescence Monte Carlo Model to Extract Concentrations of Metabolically Relevant Fluorophores From Turbid Phantoms and A Murine Tumor Model, Journal of Biomedical Optics, 2012, 第 1 作者
(33) Mechanisms of laser nanoparticle-based techniques for gene transfection—a calculation study, Journal of Biological Physics, 2009, 第 1 作者
发表著作
(1) Nano Imaging: From Fundamental Principles to Translational Medical Applications (Chapter 5: Nanoparticles for Photoacoustic Imaging), World Scientific, 2016-07, 第 1 作者

科研活动

   
科研项目
( 1 ) 基于新型液态氟碳纳米颗粒的光声超声双模成像及光声治疗研究, 主持, 国家级, 2015-01--2017-12
( 2 ) 适用于临床肿瘤成像的新型高灵敏光声成像探头与系统, 主持, 省级, 2017-01--2018-12
( 3 ) 并行采集式高速光声人体外周血管成像技术研究, 主持, 省级, 2018-01--2020-12
( 4 ) 超声/光声分子影像融合引导前列腺癌早期精准介入诊疗基础研究, 参与, 国家级, 2015-01--2019-12
( 5 ) 脑胶质瘤精准诊疗技术的关键科学问题研究, 参与, 国家级, 2015-01--2019-12
( 6 ) 中科院青促会, 主持, 部委级, 2019-01--2022-12
( 7 ) 面向狨猴脑科学研究的光声超声双模态成像仪器, 主持, 部委级, 2020-01--2021-12
参与会议
(1)用于肿瘤精准治疗影像导航的实时光声/超声成像系统   2017-04-20
(2)A novel handheld linear­array photoacoustic probe towards clinical translation for sentinel lymph node mapping   2016-10-12
(3)A novel folate receptor-targeted indocyanine green nanoprobe for in vivo dual modality photoacoustic/fluorescence imaging of breast carcinoma   2015-04-11
(4)Multifunctional phase-transition nanodroplets for dual-modality imaging and theranostic application   2014-06-14

指导学生

现指导学生

吕圣苗  硕士研究生  085400-电子信息