081703-生物化工

生物化学，生物催化，糖生物学

1999-04--2002-03   日本爱媛大学   博士
1993-09--1996-07   东北农业大学   硕士
1981-09--1985-07   哈尔滨师范大学   学士

   

2008-07~2011-07,中科院天津工业生物技术研究所, 研究员
2002-08~2008-07,日本香川产业支援财团, 研究员

   

（1） 天然咸味食品香精绿色生物制备技术, 二等奖, 省级, 2013
（2） 生物催化制备新型食品复合调味料的关键技术, 三等奖, 省级, 2011

（ 1 ） 某种梭菌D-塔格糖3-差向异构酶的核苷酸序列及其应用, 发明, 2010, 第 1 作者, 专利号: 201010264400.5
（ 2 ） 来源于戊糖片球菌的食品级L-阿拉伯糖异构酶的核苷酸序列及其应用, 发明, 2011, 第 1 作者, 专利号: 2011061700386930
（ 3 ） 一种来自鱼肉骨蛋白的鲜味食品香精及其制备方法, 发明, 2010, 第 1 作者, 专利号: 201010180294.2
（ 4 ） 瘤胃菌D-塔格糖3-差向异构酶的核苷酸序列及其应用, 发明, 2011, 第 1 作者, 专利号: 201110378798.X
（ 5 ） 一株产酸克雷伯氏菌及其在生产蒜糖醇中的应用, 发明, 2013, 第 1 作者, 专利号: 201310354386.1
（ 6 ） 来源于产酸克雷伯氏菌的核糖醇脱氢酶（RDH）及其编码基因与应用, 发明, 2013, 第 2 作者, 专利号: 201310354387.6
（ 7 ） 一株生物合成稀少糖的谷氨酸棒杆菌工程菌株及其构建方法和应用, 发明, 2014, 第 1 作者, 专利号: 201410055300.X
（ 8 ） 一株生物转化生产蒜糖醇的大肠杆菌工程菌株及其构建方法和应用, 发明, 2014, 第 5 作者, 专利号: 201410186502.8
（ 9 ） 一种利用醛缩酶生物合成2-脱氧稀少醛糖的方法, 发明, 2014, 第 1 作者, 专利号: 201410227098.4
（ 10 ） 罗汉果糖基转移酶基因UGT74AC1及其应用, 发明, 2014, 第 1 作者, 专利号: 201410671420.2
（ 11 ） 罗汉果葫芦二烯醇合成酶基因SgCbQ及其应用, 发明, 2014, 第 1 作者, 专利号: 201410671558.2
（ 12 ） 罗汉果醇合成途径中萜类化合物及其糖基化产物的合成方法, 发明, 2015, 第 5 作者, 专利号: 201510425384.6
（ 13 ） 一株胶原酶生产菌株及其胶原酶基因序列与应用, 发明, 2016, 第 5 作者, 专利号: 201610013029.2
（ 14 ） 一种褐藻胶裂解酶、其制备方法及应用, 发明, 2016, 第 5 作者, 专利号: 201610043881.4

   

[1] 蔡韬, 刘玉万, 朱蕾蕾, 苏浩, 王钰, 王国坤, 张玲玲, 朱之光, 盛翔, 毕昌昊, 马红武, 田朝光, 张学礼, 吴洽庆, 孙媛霞, 江会锋, 马延和. 二氧化碳人工生物转化. 生物工程学报[J]. 2022, 38(11): 4101-4114, http://lib.cqvip.com/Qikan/Article/Detail?id=7108545586.
[2] 朱玥明, 陈朋, 曾艳, 滕昆, 余义发, 陈成, 孙媛霞. 海藻寡糖的生物制造关键技术与应用. 中国科技成果[J]. 2022, 23(8): F0002-F0002, http://lib.cqvip.com/Qikan/Article/Detail?id=7107402650.
[3] Tian, Chaoyu, Yang, Jiangang, Liu, Cui, Chen, Peng, Zhang, Tong, Men, Yan, Ma, Hongwu, Sun, Yuanxia, Ma, Yanhe. Engineering substrate specificity of HAD phosphatases and multienzyme systems development for the thermodynamic-driven manufacturing sugars. NATURE COMMUNICATIONS[J]. 2022, 13(1): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000815263200013.
[4] 张学文, 孙媛霞. 蔗糖合成结构可控的功能性淀粉研究进展. 食品与生物技术学报[J]. 2022, 41(10): 37-48, http://lib.cqvip.com/Qikan/Article/Detail?id=7108393228.
[5] Zhang, Tong, Liu, Pi, Wei, Hongli, Sun, Xinming, Zeng, Yan, Zhang, Xuewen, Cai, Yi, Cui, Mengfei, Ma, Hongwu, Liu, Weidong, Sun, Yuanxia, Yang, Jiangang. Protein Engineering of Glucosylglycerol Phosphorylase Facilitating Efficient and Highly Regio- and Stereoselective Glycosylation of Polyols in a Synthetic System. ACS CATALYSIS[J]. 2022, 12(24): 15715-15727, [6] Dai, Longhai, Qin, Lujiao, Hu, Yumei, Huang, Jianwen, Hu, Zheyang, Min, Jian, Sun, Yuanxia, Guo, ReyTing. Structural dissection of unnatural ginsenoside-biosynthetic UDP-glycosyltransferase Bs-YjiC from Bacillus subtilis for substrate promiscuity. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2021, 534: 73-78, https://www.webofscience.com/wos/woscc/full-record/WOS:000607297600012.
[7] Ren, Chenxi, Yang, Jiangang, Zeng, Yan, Zhang, Tong, Tian, Chaoyu, Men, Yan, Sun, Yuanxia. Novel catalytic property of fructose-6-phosphate aldolase in directly conversion of two 1-hydroxyalkanones to diketones. ENZYME AND MICROBIAL TECHNOLOGY[J]. 2021, 147: http://dx.doi.org/10.1016/j.enzmictec.2021.109784.
[8] Bertelsen, Anne S, Zeng, Yan, Mielby, Line A, Sun, YuanXia, Byrne, Derek V, Kidmose, Ulla. Cross-modal Effect of Vanilla Aroma on Sweetness of Different Sweeteners among Chinese and Danish Consumers. FOOD QUALITY AND PREFERENCE[J]. 2021, 87: http://dx.doi.org/10.1016/j.foodqual.2020.104036.
[9] Jiao Li, Ge Qu, Na Shang, Peng Chen, Yan Men, Weidong Liu, Zelong Mei, Yuanxia Sun, Zhoutong Sun. Near-perfect control of the regioselective glucosylation enabled by rational design of glycosyltransferases. GREEN SYNTHESIS AND CATALYSIS[J]. 2021, 2(1): 45-53, http://dx.doi.org/10.1016/j.gresc.2021.01.005.
[10] 田朝玉, 杨建刚, 朱玥明, 孙媛霞. 甘蔗基蔗糖高附加值利用的研究进展. 广西科学[J]. 2020, 27(1): 10-19, http://lib.cqvip.com/Qikan/Article/Detail?id=7101134096.
[11] Zhu, Ping, Zeng, Yan, Chen, Peng, Men, Yan, Yang, Jiangang, Yue, Xiaoping, Zhang, Jiangang, Zhu, Yueming, Sun, Yuanxia. A one-pot two-enzyme system on the production of high value-added D-allulose from Jerusalem artichoke tubers. PROCESS BIOCHEMISTRY[J]. 2020, 88: 90-96, http://dx.doi.org/10.1016/j.procbio.2019.10.006.
[12] Zhang, Tong, Yang, Jiangang, Tian, Chaoyu, Ren, Chenxi, Chen, Peng, Men, Yan, Sun, Yuanxia. High-Yield Biosynthesis of Glucosylglycerol through Coupling Phosphorolysis and Transglycosylation Reactions. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2020, 68(51): 15249-15256, https://www.webofscience.com/wos/woscc/full-record/WOS:000603399600019.
[13] Junge, Jonas Yde, Bertelsen, Anne Sjoerup, Mielby, Line Ahm, Zeng, Yan, Sun, YuanXia, Byrne, Derek Victor, Kidmose, Ulla. Taste Interactions between Sweetness of Sucrose and Sourness of Citric and Tartaric Acid among Chinese and Danish Consumers. FOODS[J]. 2020, 9(10): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600934/.
[14] Tian, Chaoyu, Yang, Jiangang, Li, Yunjie, Zhang, Tong, Li, Jiao, Ren, Chenxi, Men, Yan, Chen, Peng, You, Chun, Sun, Yuanxia, Ma, Yanhe. Artificially designed routes for the conversion of starch to value-added mannosyl compounds through coupling in vitro and in vivo metabolic engineering strategies. METABOLIC ENGINEERING[J]. 2020, 61: 215-224, http://dx.doi.org/10.1016/j.ymben.2020.06.008.
[15] Zhang, Ying, Zeng, Yan, Cui, Yongsheng, Liu, Hanmin, Dong, Caixia, Sun, Yuanxia. Structural characterization, antioxidant and immunomodulatory activities of a neutral polysaccharide from Cordyceps militaris cultivated on hull-less barley. CARBOHYDRATE POLYMERS[J]. 2020, 235: http://dx.doi.org/10.1016/j.carbpol.2020.115969.
[16] Yan, Junjun, Chen, Peng, Zeng, Yan, Yang, Jiangang, Men, Yan, Zhu, Yueming, Sun, Yuanxia. Production of neoagarobiose from agar through a dual-enzyme and two-stage hydrolysis strategy. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 160: 288-295, http://dx.doi.org/10.1016/j.ijbiomac.2020.05.206.
[17] Li, Jiao, Yang, Jiangang, Mu, Shicheng, Shang, Na, Liu, Cui, Zhu, Yueming, Cai, Yi, Liu, Pi, Lin, Jianping, Liu, Weidong, Sun, Yuanxia, Ma, Yanhe. Efficient O-Glycosylation of Triterpenes Enabled by Protein Engineering of Plant Glycosyltransferase UGT74AC1. ACS CATALYSIS[J]. 2020, 10(6): 3629-3639, https://www.webofscience.com/wos/woscc/full-record/WOS:000526394500013.
[18] 孙媛霞. Artificially designed routes for the conversion of starch to value-added mannosyl compounds through coupling in vitro and in vivo metabolic engineering strategies. Metabolic Engineering. 2020, [19] Mu, Shicheng, Li, Jiao, Liu, Cui, Zeng, Yan, Men, Yan, Cai, Yi, Chen, Ning, Ma, Hongwu, Sun, Yuanxia. Effective Glycosylation of Cucurbitacin Mediated by UDP-Glycosyltransferase UGT74AC1 and Molecular Dynamics Exploration of Its Substrate Binding Conformations. CATALYSTS[J]. 2020, 10(12): https://doaj.org/article/ee80cad14bff4ee89ae6a84986c78997.
[20] Wang, Wei, Yang, Jiangang, Sun, Yuanxia, Li, Zhimin, You, Chun. Artificial ATP-Free in Vitro Synthetic Enzymatic Biosystems Facilitate Aldolase-Mediated C-C Bond Formation for Biomanufacturing. ACS CATALYSIS[J]. 2020, 10(2): 1264-1271, https://www.webofscience.com/wos/woscc/full-record/WOS:000508466700030.
[21] 曾艳, 朱玥明, 张建刚, 岳晓平, 孙媛霞. 大豆发酵食品中的活性肽及其生理功能研究进展. 大豆科学[J]. 2019, 159-166, http://lib.cqvip.com/Qikan/Article/Detail?id=68687588504849574849485053.
[22] 岳晓平, 陈朋, 朱玥明, 曾艳, 刘汉民, 刘红彦, 王敏, 孙媛霞. 米曲霉酸性蛋白酶基因在毕赤酵母中的异源表达及酶学性质. 生物工程学报[J]. 2019, 415-424, http://lib.cqvip.com/Qikan/Article/Detail?id=83728785504849574851484857.
[23] Men, Yan, Zhu, Ping, Zhu, Yueming, Zeng, Yan, Yang, Jiangang, Sun, Yuanxia. The development of low-calorie sugar and functional jujube food using biological transformation and fermentation coupling technology. FOOD SCIENCE & NUTRITION[J]. 2019, 7(4): 1302-1310, [24] 孙媛霞, 杨建刚, 田朝玉, 马延和. 功能寡糖绿色生物合成技术的研究进展. 生物产业技术[J]. 2019, 26-33, http://lib.cqvip.com/Qikan/Article/Detail?id=7002787396.
[25] Yan, Junjun, Chen, Peng, Zeng, Yan, Men, Yan, Mu, Shicheng, Zhu, Yueming, Chen, Yefu, Sun, Yuanxia. The Characterization and Modification of a Novel Bifunctional and Robust Alginate Lyase Derived from Marinimicrobium sp. H1. MARINE DRUGS[J]. 2019, 17(10): http://dx.doi.org/10.3390/md17100545.
[26] Tian, Chaoyu, Yang, Jiangang, Zeng, Yan, Zhang, Tong, Zhou, Yingbiao, Men, Yan, You, Chun, Zhu, Yueming, Sun, Yuanxia. Biosynthesis of Raffinose and Stachyose from Sucrose via an In Vitro Multienzyme System. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2019, 85(2): https://www.webofscience.com/wos/woscc/full-record/WOS:000455226800024.
[27] Wang, Wen, He, Ping, Zhao, Dongdong, Ye, Lijun, Dai, Longhai, Zhang, Xueli, Sun, Yuanxia, Zheng, Jing, Bi, Changhao. Construction of Escherichia coli cell factories for crocin biosynthesis. MICROBIAL CELL FACTORIES[J]. 2019, 18(1): http://dx.doi.org/10.1186/s12934-019-1166-1.
[28] Yang, Jiangang, Zhang, Tong, Tian, Chaoyu, Zhu, Yueming, Zeng, Yan, Men, Yan, Chen, Peng, Sun, Yuanxia, Ma, Yanhe. Multi-enzyme systems and recombinant cells for synthesis of valuable saccharides: Advances and perspectives. BIOTECHNOLOGY ADVANCESnull. 2019, 37(7): http://dx.doi.org/10.1016/j.biotechadv.2019.06.005.
[29] Yang, Jiangang, Tian, Chaoyu, Zhang, Tong, Ren, Chenxi, Zhu, Yueming, Zeng, Yan, Men, Yan, Sun, Yuanxia, Ma, Yanhe. Development of food-grade expression system for d-allulose 3-epimerase preparation with tandem isoenzyme genes in Corynebacterium glutamicum and its application in conversion of cane molasses to D-allulose. BIOTECHNOLOGY AND BIOENGINEERING[J]. 2019, 116(4): 745-756, [30] Dai, Longhai, Li, Jiao, Yang, Jiangang, Men, Yan, Zeng, Yan, Cai, Yi, Sun, Yuanxia. Enzymatic Synthesis of Novel Glycyrrhizic Acid Glucosides Using a Promiscuous Bacillus Glycosyltransferase. CATALYSTS[J]. 2018, 8(12): http://dx.doi.org/10.3390/catal8120615.
[31] Chen, Peng, Zhu, Yueming, Men, Yan, Zeng, Yan, Sun, Yuanxia. Purification and Characterization of a Novel Alginate Lyase from the Marine Bacterium Bacillus sp. Alg07. MARINE DRUGS[J]. 2018, 16(3): https://doaj.org/article/80012be30fa64fb1b612574bc878c939.
[32] Liu, Can, Dai, Longhai, Liu, Yueping, Dou, Dequan, Sun, Yuanxia, Ma, Lanqing. Pharmacological activities of mogrosides. FUTURE MEDICINAL CHEMISTRY[J]. 2018, 10(8): 845-850, https://www.webofscience.com/wos/woscc/full-record/WOS:000431873100003.
[33] 孙媛霞. 枯草芽孢杆菌来源糖基转移酶合成原人参三醇型人参皂苷. J. Agric. Food Chem.. 2018, [34] 孙媛霞. 来自海洋微生物褐藻胶裂解酶的纯化与表征. Marine Drugs. 2018, [35] Zhang, Ying, Zeng, Yan, Men, Yan, Zhang, Jiangang, Liu, Hanmin, Sun, Yuanxia. Structural characterization and immunomodulatory activity of exopolysaccharides from submerged culture of Auricularia auricula-judae. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2018, 115: 978-984, http://dx.doi.org/10.1016/j.ijbiomac.2018.04.145.
[36] Yang, Jiangang, Zhu, Yueming, Qu, Ge, Zeng, Yan, Tian, Chaoyu, Dong, Caixia, Men, Yan, Dai, Longhai, Sun, Zhoutong, Sun, Yuanxia, Ma, Yanhe. Biosynthesis of dendroketose from different carbon sources using in vitro and in vivo metabolic engineering strategies. BIOTECHNOLOGY FOR BIOFUELS[J]. 2018, 11(1): https://doaj.org/article/96f147a8ff334e1fb1770283fe511793.
[37] Dong, CaiXia, Zhang, WenSheng, Sun, QiLi, Jiang, YunJia, Fu, Zheng, Zhang, Ying, Du, Juan, Sun, YuanXia, Tao, Ning, Yao, Zhi. Structural characterization of a pectin-type polysaccharide from Curcuma kwangsiensis and its effects on reversing MDSC-mediated T cell suppression. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2018, 115: 1233-1240, http://dx.doi.org/10.1016/j.ijbiomac.2018.04.153.
[38] Dai, Longhai, Li, Jiao, Yang, Jiangang, Zhu, Yueming, Men, Yan, Zeng, Yan, Cai, Yi, Dong, Caixia, Dai, Zhubo, Zhang, Xueli, Sun, Yuanxia. Use of a Promiscuous Glycosyltransferase from Bacillus subtilis 168 for the Enzymatic Synthesis of Novel Protopanaxatriol-Type Ginsenosides. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2018, 66(4): 943-949, https://www.webofscience.com/wos/woscc/full-record/WOS:000424313300023.
[39] Dai, Longhai, Liu, Can, Li, Jiao, Dong, Caixia, Yang, Jiangang, Dai, Zhubo, Zhang, Xueli, Sun, Yuanxia. One-Pot Synthesis of Ginsenoside Rh2 and Bioactive Unnatural Ginsenoside by Coupling Promiscuous Glycosyltransferase from Bacillus subtilis 168 to Sucrose Synthase. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2018, 66(11): 2830-2837, https://www.webofscience.com/wos/woscc/full-record/WOS:000428356200037.
[40] 刘灿, 马兰青, 孙媛霞. 罗汉果甜苷降糖机制及生物合成研究进展. 天然产物研究与开发[J]. 2018, 30(11): 2023-2031, http://lib.cqvip.com/Qikan/Article/Detail?id=7000933527.
[41] Zhang, Jiangang, Yue, Xiaoping, Zeng, Yan, Hua, Erbin, Wang, Min, Sun, Yuanxia. Bacillus amyloliquefaciens levan and its silver nanoparticles with antimicrobial properties. BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT[J]. 2018, 32(6): 1583-1589, https://doaj.org/article/713242c8938b4a4f95859265554c3868.
[42] Zeng, Yan, Zhang, Jiangang, Zhang, Ying, Men, Yan, Zhang, Bo, Sun, Yuanxia. Prebiotic, Immunomodulating, and Antifatigue Effects of Konjac Oligosaccharide. JOURNAL OF FOOD SCIENCE[J]. 2018, 83(12): 3110-3117, http://dx.doi.org/10.1111/1750-3841.14376.
[43] Zhou, Yingbiao, Zhu, Yueming, Dai, Longhai, Men, Yan, Wu, Jinhai, Zhang, Juankun, Sun, Yuanxia. Efficiency Analysis and Mechanism Insight of that Whole-Cell Biocatalytic Production of Melibiose from Raffinose with Saccharomyces cerevisiae. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY[J]. 2017, 181(1): 407-423, http://124.16.173.210/handle/834782/2274.
[44] Yang, Jiangang, Sun, Shangshang, Men, Yan, Zeng, Yan, Zhu, Yueming, Sun, Yuanxia, Ma, Yanhe. Transformation of formaldehyde into functional sugars via multi-enzyme stepwise cascade catalysis. CATALYSIS SCIENCE & TECHNOLOGY[J]. 2017, 7(16): 3459-3463, https://www.webofscience.com/wos/woscc/full-record/WOS:000407636600004.
[45] 曾艳, 张颖, 郝学财, 邓莉, 孙媛霞. 电子舌对不同工艺制备的海带调味品味感特征分析. 中国调味品[J]. 2017, 42(1): 80-84, http://lib.cqvip.com/Qikan/Article/Detail?id=671078231.
[46] 孙媛霞. 构建酵母工程菌利用棉籽糖合成蜜二糖. J Ind Microbiol Biotechnol. 2017, [47] 孙媛霞. 微生物来源糖基转移酶及其合成糖苷应用. Journal of Biotechnology. 2017, [48] Dai, Longhai, Li, Jiao, Yao, Peiyuan, Zhu, Yueming, Men, Yan, Zeng, Yan, Yang, Jiangang, Sun, Yuanxia. Exploiting the aglycon promiscuity of glycosyltransferase Bs-YjiC from Bacillus subtilis and its application in synthesis of glycosides. JOURNAL OF BIOTECHNOLOGY[J]. 2017, 248: 69-76, http://dx.doi.org/10.1016/j.jbiotec.2017.03.009.
[49] Zhou, Yingbiao, Zhu, Yueming, Men, Yan, Dong, Caixia, Sun, Yuanxia, Zhang, Juankun. Construction of engineered Saccharomyces cerevisiae strain to improve that whole-cell biocatalytic production of melibiose from raffinose. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY[J]. 2017, 44(3): 489-501, https://www.webofscience.com/wos/woscc/full-record/WOS:000395204400016.
[50] 曾艳, 张颖, 门燕, 孙媛霞. 羧甲基果聚糖的胶原肽修饰及其活性研究. 食品工业科技[J]. 2017, 38(9): 49-54, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5987565&detailType=1.
[51] Liu, Can, Dai, Longhai, Liu, Yueping, Rong, Long, Dou, Dequan, Sun, Yuanxia, Ma, Lanqing. Antiproliferative Activity of Triterpene Glycoside Nutrient from Monk Fruit in Colorectal Cancer and Throat Cancer. NUTRIENTS[J]. 2016, 8(6): http://124.16.173.210/handle/834782/2908.
[52] Zhang, Jiangsheng, Dai, Longhai, Yang, Jiangang, Liu, Can, Men, Yan, Zeng, Yan, Cai, Yi, Zhu, Yueming, Sun, Yuanxia. Oxidation of Cucurbitadienol Catalyzed by CYP87D18 in the Biosynthesis of Mogrosides from Siraitia grosvenorii. PLANT AND CELL PHYSIOLOGY[J]. 2016, 57(5): 1000-1007, http://dx.doi.org/10.1093/pcp/pcw038.
[53] Chen, Jingqi, Zhu, Yueming, Fu, Gang, Song, Yafeng, Jin, Zhaoxia, Sun, Yuanxia, Zhang, Dawei. High-level intra- and extra-cellular production of D-psicose 3-epimerase via a modified xylose-inducible expression system in Bacillus subtilis. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY[J]. 2016, 43(11): 1577-1591, http://124.16.173.210/handle/834782/2942.
[54] 孙媛霞. 一株新型海洋微生物菌基因组与转录组分析及其褐藻胶降解机制. Scientific Reports. 2016, [55] 孙媛霞. 谷氨酸棒杆菌途径构建与甘油合成稀少糖. Journal of Agricultural and Food Chemistry. 2016, [56] Zhu, Yueming, Chen, Peng, Bao, Yunjuan, Men, Yan, Zeng, Yan, Yang, Jiangang, Sun, Jibin, Sun, Yuanxia. Complete genome sequence and transcriptomic analysis of a novel marine strain Bacillus weihaiensis reveals the mechanism of brown algae degradation. SCIENTIFIC REPORTS[J]. 2016, 6: http://124.16.173.210/handle/834782/2284.
[57] Yang, Jiangang, Zhu, Yueming, Men, Yan, Sun, Shangshang, Zeng, Yan, Zhang, Ying, Sun, Yuanxia, Ma, Yanhe. Pathway Construction in Corynebacterium glutamicum and Strain Engineering To Produce Rare Sugars from Glycerol. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2016, 64(50): 9497-9505, http://124.16.173.210/handle/834782/2280.
[58] 李星硕, 朱玥明, 管于平, 柏玮, 贾士儒, 孙媛霞. 产胶原酶菌株的筛选鉴定、发酵优化及胶原酶纯化. 微生物学报[J]. 2016, 56(6): 1034-1043, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5713265&detailType=1.
[59] 张颖, 曾艳, 张丽姣, 郁鹏, 孙媛霞. 解淀粉芽孢杆菌果聚糖的化学修饰与抗氧化、抗肿瘤活性研究. 食品工业科技[J]. 2016, 37(13): 96-100, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5729011&detailType=1.
[60] Chen, Jingqi, Zhao, Liuqun, Fu, Gang, Zhou, Wenjuan, Sun, Yuanxia, Zheng, Ping, Sun, Jibin, Zhang, Dawei. A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis. MICROBIAL CELL FACTORIES[J]. 2016, 15(1): http://124.16.173.210/handle/834782/2246.
[61] 孙媛霞. Biosynthesis of L-sorbose/psicose based on C-C bond formation catalyzed by aldolase in an engineered Corynebacterium glutamicum strain. Applied and Environmental Microbiology. 2015, [62] 刘灿, 蔡天宇, 赵晓萌, 马兰青, 窦德泉, 孙媛霞. 罗汉果提取物诱导肺癌细胞A549凋亡的研究. 中国药理学通报[J]. 2015, 31(9): 1310-1314, http://lib.cqvip.com/Qikan/Article/Detail?id=665880826.
[63] Yang, Jiangang, Zhu, Yueming, Li, Jitao, Men, Yan, Sun, Yuanxia, Ma, Yanhe. Biosynthesis of Rare Ketoses Through Constructing a Recombination Pathway in an Engineered Corynebacterium glutamicum. BIOTECHNOLOGY AND BIOENGINEERING[J]. 2015, 112(1): 168-180, https://www.webofscience.com/wos/woscc/full-record/WOS:000345517800017.
[64] Dong, CaiXia, Zhang, LiJiao, Xu, Rong, Zhang, Gong, Zhou, YingBiao, Han, XiaoQiang, Zhang, Ying, Sun, YuanXia. Structural characterization and immunostimulating activity of a levan-type fructan from Curcuma kwangsiensis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2015, 77: 99-104, http://dx.doi.org/10.1016/j.ijbiomac.2015.03.009.
[65] 张丽姣, 曾艳, 张颖, 宋诙, 贾士儒, 孙媛霞. 解淀粉芽孢杆菌胞外多糖发酵条件的优化. 食品工业科技[J]. 2015, 36(9): 214-219, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5399654&detailType=1.
[66] Dou, Dequan, Leng, Pingsheng, Li, Yuehua, Zeng, Yan, Sun, Yuanxia. Comparative study of antioxidant compounds and antiradical properties of the fruit extracts from three varieties of Crataegus pinnatifida. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE[J]. 2015, 52(1): 430-436, https://www.webofscience.com/wos/woscc/full-record/WOS:000347523800044.
[67] Zeng, Yan, Dou, Dequan, Zhang, Ying, Zhang, Lijiao, Sun, Yuanxia. Rare Sugars and Antioxidants in Itea virginica, Itea oblonga Hand.-Mazz., and Itea yunnanensis Franch Leaves. INTERNATIONAL JOURNAL OF FOOD PROPERTIES[J]. 2015, 18(11): 2549-2560, http://124.16.173.210/handle/834782/1505.
[68] Bai, Wei, Shen, Jie, Zhu, Yueming, Men, Yan, Sun, Yuanxia, Ma, Yanhe. Characteristics and Kinetic Properties of L-Rhamnose Isomerase from Bacillus Subtilis by Isothermal Titration Calorimetry for the Production of D-Allose. FOOD SCIENCE AND TECHNOLOGY RESEARCH[J]. 2015, 21(1): 13-22, http://124.16.173.210/handle/834782/1421.
[69] 孙媛霞. Biosynthesis of rare ketoses through constructing a simulated-gluconeogenesis pathway in an engineered Corynebacterium glutamicum. Biotechnology and bioengineering. 2015, [70] Dai, Longhai, Liu, Can, Zhu, Yueming, Zhang, Jiangsheng, Men, Yan, Zeng, Yan, Sun, Yuanxia. Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii. PLANT AND CELL PHYSIOLOGY[J]. 2015, 56(6): 1172-1182, http://dx.doi.org/10.1093/pcp/pcv043.
[71] 孙媛霞. Multi-sites directed mutagenesis of 2-deoxy-D-ribose 5-phosphate aldolase and whole-cell transformation to efficiently biosynthesize. Applied Microbiology and Biotechnology. 2015, [72] Li, Jitao, Yang, Jiangang, Men, Yan, Zeng, Yan, Zhu, Yueming, Dong, Caixia, Sun, Yuanxia, Ma, Yanhe. Biosynthesis of 2-deoxysugars using whole-cell catalyst expressing 2-deoxy-d-ribose 5-phosphate aldolase. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2015, 99(19): 7963-7972, http://124.16.173.210/handle/834782/1568.
[73] Liu, Can, Zeng, Yan, Dai, LongHai, Cai, TianYu, Zhu, YueMing, Dou, DeQuan, Ma, LanQing, Sun, YuanXia. Mogrol represents a novel leukemia therapeutic, via ERK and STAT3 inhibition. AMERICAN JOURNAL OF CANCER RESEARCH[J]. 2015, 5(4): 1308-+, http://124.16.173.210/handle/834782/1496.
[74] 陈朋, 朱玥明, 韩文佳, 门燕, 贾士儒, 孙媛霞. 产褐藻胶裂解酶菌种的筛选、鉴定及发酵条件优化. 食品科学[J]. 2015, 36(15): 105-111, http://lib.cqvip.com/Qikan/Article/Detail?id=665811351.
[75] Zeng, Yan, Zhang, Ying, Zhang, Lijiao, Cui, Shimao, Sun, Yuanxia. Structural Characterization and Antioxidant and Immunomodulation Activities of Polysaccharides from the Spent Rice Substrate of Cordyceps militaris. FOOD SCIENCE AND BIOTECHNOLOGY[J]. 2015, 24(5): 1591-1596, http://124.16.173.210/handle/834782/1566.
[76] 张颖, 曾艳, 张丽姣, 崔世茂, 孙媛霞. 不同食用菌菌糠多糖的组分分析与抗氧化活性评价. 食品科学[J]. 2015, 18-23, http://lib.cqvip.com/Qikan/Article/Detail?id=83807588504849534853484854.
[77] Zhu, Yueming, Li, Hongyi, Liu, Pingping, Yang, Jiangang, Zhang, Xueli, Sun, Yuanxia. Construction of allitol synthesis pathway by multi-enzyme coexpression in Escherichia coli and its application in allitol production. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY[J]. 2015, 42(5): 661-669, http://124.16.173.210/handle/834782/1459.
[78] Yang, Jiangang, Li, Jitao, Men, Yan, Zhu, Yueming, Zhang, Ying, Sun, Yuanxia, Ma, Yanhe. Biosynthesis of L-Sorbose and L-Psicose Based on C-C Bond Formation Catalyzed by Aldolases in an Engineered Corynebacterium glutamicum Strain. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2015, 81(13): 4284-4294, http://124.16.173.210/handle/834782/1490.
[79] 张丽姣, 曾艳, 张换, 张颖, 门燕, 孙媛霞. 海带酶解液的戊糖片球菌发酵及其产物的抗氧化性、抑菌性. 食品科学[J]. 2014, 164-169, http://lib.cqvip.com/Qikan/Article/Detail?id=83807588504849525049485152.
[80] 韩文佳, 朱現明, 柏玮, 何森健, 张同存, 孙媛霞. 双酶偶联转化果糖制备含有稀少糖的混合糖液. 生物工程学报[J]. 2014, 30(1): 90-97, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5061929&detailType=1.
[81] 窦德泉, 曾艳, 朱玥明, 刘灿, 孙媛霞. 弗吉尼亚鼠刺叶片中稀少糖醇生物转化及分离制备. 食品科学[J]. 2014, 35(22): 28-32,  http://dx.doi.org/10.7506/spkx1002-6630-201422006.
[82] Tseng, ChihWen, Liao, ChienYi, Sun, Yuanxia, Peng, ChiChung, Tzen, Jason T C, Guo, ReyTing, Liu, JeRuei. Immobilization of Clostridium cellulolyticum D-Psicose 3-Epimerase on Artificial Oil Bodies. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2014, 62(28): 6771-6776, http://dx.doi.org/10.1021/jf502022w.
[83] 张黎丽, 朱玥明, 门燕, 康振奎, 孙媛霞. 来源于瘤胃菌Ruminococcus sp.的D-阿洛酮糖3-差向异构酶的底物结合位点分析. 微生物学通报[J]. 2014, 41(5): 811-817, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5145294&detailType=1.
[84] 张颖, 曾艳, 张丽姣, 崔世茂, 孙媛霞. 蛹虫草菌糠多糖的分离纯化及结构组成分析. 食品科学[J]. 2014, 35(13): 54-58,  http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=spkx201413011.
[85] 孙媛霞. Co-expression of D-glucose isomerase and D-psicose 3-epimerase in E. coli and development of an efficient one step conversion of D-glucose to D-psicose. Enzyme and Microbial Technology. 2014, [86] Men, Yan, Zhu, Yueming, Zeng, Yan, Izumori, Ken, Sun, Yuanxia, Ma, Yanhe. Co-expression of D-glucose isomerase and D-psicose 3-epimerase: Development of an efficient one-step production of D-psicose. ENZYME AND MICROBIAL TECHNOLOGY[J]. 2014, 64-65: 1-5, http://dx.doi.org/10.1016/j.enzmictec.2014.06.001.
[87] Men, Yan, Zhu, Yueming, Zhang, Lili, Kang, Zhenkui, Izumori, Ken, Sun, Yuanxia, Ma, Yanhe. Enzymatic conversion of D-galactose to D-tagatose: Cloning, overexpression and characterization of L-arabinose isomerase from Pediococcus pentosaceus PC-5. MICROBIOLOGICAL RESEARCH[J]. 2014, 169(2-3): 171-178, http://dx.doi.org/10.1016/j.micres.2013.07.001.
[88] Han, Wenjia, Zhu, Yueming, Men, Yan, Yang, Jiangang, Liu, Can, Sun, Yuanxia. Production of allitol from D-psicose by a novel isolated strain of Klebsiella oxytoca G4A4. JOURNAL OF BASIC MICROBIOLOGY[J]. 2014, 54(10): 1073-1079, http://dx.doi.org/10.1002/jobm.201300647.
[89] 孙媛霞. 壳聚糖固定D-阿洛酮糖3-差向异构酶生产D-阿洛酮糖. 食品与发酵工业. 2013, [90] 孙媛霞. Utilization of Candida utilis cells for the production of yeast extract:Effects of enzyme types, dosages and treatment time. Advance Journal of Food Science and Technology. 2013, [91] Takashi Hishiike, Masahiro Ogawa, Shigeru Hayakawa, Daichi Nakajima, Daichi Nakajima, Hisaka Ooshima, Yuanxia Sun. Transepithelial Transports of Rare SugarD‑Psicose in Human Intestine. J. AGRIC. FOOD CHEM[J]. 2013, 7381−7386-, http://124.16.173.210/handle/311007/710.
[92] Zeng, Yan, Zhang, Huan, Guan, Yuping, Zhang, Lili, Sun, Yuanxia. Comparative study on the effects of d-psicose and d-fructose in the Maillard reaction with beta-lactoglobulin. FOOD SCIENCE AND BIOTECHNOLOGY[J]. 2013, 22(2): 341-346, http://124.16.173.210/handle/834782/1273.
[93] Xiaobo Li, Yueming Zhu, Yan Zeng, Tongcun Zhang, Yuanxia Sun. Overexpression of D-psicose 3-epimerase from Clostridium cellulolyticum H10 in Bacillus subtilis and its Prospect for D-psicose Production. ADVANCEJOURNALOFFOODSCIENCEANDTECHNOLOGY[J]. 2013, 5(3): 264-269, http://124.16.173.210/handle/311007/709.
[94] Dequan Dou, Pingsheng Leng, Yuehua Li, Yan Zeng, Yuanxia Sun. Comparative study of antioxidant compounds and antiradical properties of the fruit extracts from three varieties of Crataegus pinnatifida. J FOOD SCI TECHNOL[J]. 2013, http://124.16.173.210/handle/311007/707.
[95] Yan Zeng, Huan Zhang, Yuping Guan, Lili Zhang, Yuanxia Sun. Comparative Study on the Effects of D-Psicose and D-Fructose in the Maillard Reaction with β-Lactoglobulin. FOOD SCI. BIOTECHNOL.[J]. 2013, 22(2): 341-346, http://124.16.173.210/handle/311007/708.
[96] 李晓波, 朱玥明, 柏玮, 张同存, 何森健, 孙媛霞. 壳聚糖固定D-阿洛酮糖3-差向异构酶转化D-阿洛酮糖. 食品工业科技[J]. 2013, 34(17): 158-162, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=4939605&detailType=1.
[97] Hishiike, Takashi, Ogawa, Masahiro, Hayakawa, Shigeru, Nakajima, Daichi, OCharoen, Siwaporn, Ooshima, Hisaka, Sun, Yuanxia. Transepithelial Transports of Rare Sugar D-Psicose in Human Intestine. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2013, 61(30): 7381-7386, http://124.16.173.210/handle/834782/1275.
[98] 孙媛霞. 响应面法优化海带多糖的酶法提取工艺及其抗氧化研究. 食品工业科技. 2013, [99] Chan, HsiuChien, Zhu, Yueming, Hu, Yumei, Ko, TzuPing, Huang, ChunHsiang, Ren, Feifei, Chen, ChunChi, Ma, Yanhe, Guo, ReyTing, Sun, Yuanxia. Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars. PROTEIN & CELL[J]. 2012, 3(2): 123-131, http://124.16.173.210/handle/311007/725.
[100] 张倩倩, 管于平, 刁爱坡, 孙媛霞. 产朊假丝酵母培养条件的优化研究. 中国调味品[J]. 2012, http://124.16.173.210/handle/312001/331.
[101] Zhu, Yueming, Men, Yan, Bai, Wei, Li, Xiaobo, Zhang, Lili, Sun, Yuanxia, Ma, Yanhe. Overexpression of D-psicose 3-epimerase from Ruminococcus sp. in Escherichia coli and its potential application in D-psicose production. BIOTECHNOLOGY LETTERS[J]. 2012, 34(10): 1901-1906, http://www.irgrid.ac.cn/handle/1471x/483706.
[102] Yueming Zhu, Yan Men, Wei Bai, Xiaobo Li, Lili Zhang, Yuanxia Sun, Yanhe Ma. Overexpression of D-psicose 3-epimerase from Ruminococcussp. in Escherichia coliand its potential application in D-psicose production. BIOTECHNOL LETT[J]. 2012, http://124.16.173.210/handle/311007/608.
[103] 张换, 曾艳, 管于平, 刁爱坡, 孙媛霞. 响应面法优化海带多糖的酶法提取工艺及抗氧化研究. 食品科技[J]. 2012, http://124.16.173.210/handle/312001/332.
[104] 孙媛霞. Overexpression of D-psicose 3-epimerase from Ruminococcus sp. In Escherichia coli and its prospect for D-psicose production. Biotechnology Letters. 2012, [105] 门燕, 朱玥明, 管于平, 张同存, 何森健, 孙媛霞. 生物转化生产D-塔格糖的食品级菌种选育及L-阿拉伯糖异构酶的克隆表达. 生物工程学报[J]. 2012, 28(5): 592-601, http://lib.cqvip.com/Qikan/Article/Detail?id=41939458.
[106] Zeng, Yan, Zhang, Xiaoxi, Guan, Yuping, Sun, Yuanxia. Enzymatic hydrolysates from tuna backbone and the subsequent Maillard reaction with different ketohexoses. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY[J]. 2012, 47(6): 1293-1301, http://www.irgrid.ac.cn/handle/1471x/427375.
[107] 柏玮, 朱玥明, 门燕, 李晓波, 何森健, 孙媛霞. 以D-果糖为原料利用新型异构酶转化生产D-阿洛糖. 生物工程学报[J]. 2012, 28(4): 457-465, http://lib.cqvip.com/Qikan/Article/Detail?id=41695014.
[108] Liu, Ling, Wu, Junhua, Zhang, Jinlu, Li, Zhenjing, Wang, Changlu, Chen, Mianhua, Wang, Yurong, Sun, Yuanxia, Wang, Likui, Luo, Cheng. A compatibility assay of ursolic acid and foodborne microbial exopolysaccharides by antioxidant power and anti-proliferative properties in hepatocarcinoma cells. JOURNAL OF FOOD AGRICULTURE & ENVIRONMENT[J]. 2012, 10(2): 111-114, http://www.irgrid.ac.cn/handle/1471x/483705.
[109] 孙媛霞, 管于平. 一种来自鱼肉骨蛋白的鲜味食品香精及其制备方法. 2011, http://124.16.173.210/handle/0/159.
[110] 朱玥明, 孙媛霞. 某种梭菌D-塔格糖3-差向异构酶的核苷酸序列及其应用. 2011, http://124.16.173.210/handle/0/160.
[111] 曾艳, 孙媛霞, 管于平. 来源于贝类加工副产物的生物活性肽及其制备方法. 2011, http://124.16.173.210/handle/0/177.
[112] 孙媛霞, 朱玥明. 来源于戊糖片球菌的食品级L-阿拉伯糖异构酶的核苷酸序列及其应用. 2011, http://124.16.173.210/handle/0/161.
[113] Yuanxia Sun, Yin Li, Hui Song, Yang Zhu. Microbial fermentation for Food preservation. NATURAL ANTIMICROBIALS IN FOOD SAFETY AND QUALITY. 2011, http://124.16.173.210/handle/311007/518.
[114] Yuanxia Sun, Shigeru Hayakawa, Masahiro Ogawa, Supaporn Naknukool, Yupin Guan, Yoshiyuki Matsumoto. Evaluation of Angiotensin I-Converting Enzyme (ACE) Inhibitory Activities of Hydrolysates Generated from Byproducts of Freshwater Clam. FOOD SCI. BIOTECHNOL.[J]. 2011, 20(2): http://124.16.173.210/handle/311007/597.
[115] Sun, Yuanxia, Hayakawa, Shigeru, Ogawa, Masahiro, Naknukool, Supaporn, Guan, Yupin, Matsumoto, Yoshiyuki. Evaluation of angiotensin I-converting enzyme (ACE) inhibitory activities of hydrolysates generated from byproducts of freshwater clam. FOOD SCIENCE AND BIOTECHNOLOGY[J]. 2011, 20(2): 303-310, http://www.irgrid.ac.cn/handle/1471x/419193.
[116] 孙媛霞, 朱玥明. 瘤胃菌D-塔格糖-3-差向异构酶的核苷酸序列及其应用. 2011, http://124.16.173.210/handle/0/186.
[117] 张晓溪, 曾艳, 张泽生, 孙媛霞. 果糖与氨基酸美拉德反应产物的抗氧化性研究. 食品工业科技[J]. 2011, 32(6): 175-178, http://124.16.173.210/handle/0/84.
[118] Zeng, Yan, Zhang, Xiaoxi, Guan, Yuping, Sun, Yuanxia. Characteristics and Antioxidant Activity of Maillard Reaction Products from Psicose-Lysine and Fructose-Lysine Model Systems. JOURNAL OF FOOD SCIENCE[J]. 2011, 76(3): C398-C403, http://www.irgrid.ac.cn/handle/1471x/483707.
[119] 孙媛霞, 管于平. 来源与海洋鱼类加工副产物的生物活性肽及制备方法. 2011, http://124.16.173.210/handle/0/158.
[120] Li, Yanjun, Zhu, Yueming, Liu, Anjun, Sun, Yuanxia. Identification and characterization of a novel l-arabinose isomerase from Anoxybacillus flavithermus useful in d-tagatose production. EXTREMOPHILES[J]. 2011, 15(3): 441-450, http://www.irgrid.ac.cn/handle/1471x/483710.
[121] 张晓溪, 曾艳, 张泽生, 孙媛霞. 果糖与氨基酸美拉德反应产物的抗氧化性研究. 食品工业科技[J]. 2011, 32(6): 175-178, http://124.16.173.210/handle/0/84.
[122] 张陆霞, 管于平, 姜玮, 张泽生, 孙媛霞. 鳕鱼排蛋白水解及其营养风味型美拉德反应产物的制备. 食品与发酵工业[J]. 2010, 70-74, http://lib.cqvip.com/Qikan/Article/Detail?id=35888774.
[123] Yuanxia SUN, Huihong JIANG, Yuping GUAN, Wei BAl, Wei JIANG. Influence of Rare Sugar, D-psicose, on Antioxidant and Antimicrobial Properties of Foods in Heat Processing. 2010年第三届国际食品安全高峰论坛null. 2010, http://124.16.173.210/handle/0/67.
[124] 孙媛霞. Influence of D-Psicose on Quality and Functional Properties of an Aerated Food System Containing Egg.. 2008, [125] Sun, Yuanxia, Hayakawa, Shigeru, Ogawa, Masahiro, Izumori, Ken. Antioxidant properties of custard pudding dessert containing rare hexose, D-psicose. FOOD CONTROL[J]. 2007, 18(3): 220-227, https://www.webofscience.com/wos/woscc/full-record/WOS:000241048200006.
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（ 1 ） 在食品安全与质量中自然抗微生物作用-微生物发酵与食品保藏, Natural Antimicrobials in Food Safety and Quality-Microbial Fermentation for Food Preservation, CAB international, 2011-09, 第 1 作者

   

（ 1 ） 功能性稀少糖的生物转化, 主持, 部委级, 2011-01--2013-12
（ 2 ） 复合蛋白酶催化技术生产8000吨富肽天然调味料高技术产业化, 主持, 部委级, 2011-01--2013-12
（ 3 ） 褐藻多糖及其微生物发酵食品添加剂的开发利用, 主持, 省级, 2012-10--2014-09
（ 4 ） 糖工程关键技术与重大产品开发, 参与, 国家级, 2012-01--2015-12
（ 5 ） 糖质资源高效生物利用关键技术研究, 参与, 国家级, 2013-01--2017-12
（ 6 ） 基于酶催化羟醛反应立体选择性构建谷氨酸棒杆菌模式细胞生物合成稀少糖, 主持, 国家级, 2016-01--2019-12

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