General

Personal Data

First Name: Chun

Last Name: Wang

Ph. D, Associate Professor

Date of Birth: 1963-09-09

Nationality: Chinese

Tel: +86-28-82890812

Email: wangchun@cib.ac.cn

Address

Chengdu Institute of Biology, Chinese Academy of Sciences.

No.9 Section 4, Renmin Nan Road, Chengdu, Sichuan, P.R. China

P. O. BOX 416, Chengdu, 610041, China.

 


Research Areas


Organic Chemistry, medicinal chemistry, materials chemistry.

Education

Ph.D, 2007.12, Chemistry, Western Michigan University, Kalamazoo, MI., U.S.A.

MBA, 2002.12, Colorado Technical University, Sioux Falls, SD., U.S.A.

M.S., 1995.05, Chemistry, Central South University, Changsha, China.

B.S., 1984.08, Fine Chemical Engineering, Kunming University of Science & Technology, Kunming, China.


Experience

Postdoctoral Fellow, 2008.02-2008.10, Department of Chemistry & Biochemistry, University of South Carolina, Columbia, SC, U.S.A.

Senior Chemist, 2008.10- 2009.07, Micropoint BioSciences Inc, Sunnyvale, CA, U.S.A.

Associate Professor, 2009.08—Present, Chengdu Institute of Biology, Chinese Academy of Sciences.


Publications

1. Shen, X. Y., Liu, X. S., Wan, X. L., Fan, X., He, H. Y., Wei , R., Pu, W. C.,  Peng, Y. and Wang, C.*, “Discovery of Coumarin as Microtuble Affinity-Regulating Kinase 4 Inhibitor That Sensitize Hepatocellular Carcinoma to Paclitaxel", Frontiers in Chemistry, 2019, 7, 1-doi.org/10.3389/fchem.2019.00366.



2. Shen, X. Y.; Zhou, Q., Xiong, W.; Pu, W. C.; Zhang, W.; Zhang, G. L.* and Wang, C.*, Synthesis of 5-subsituted flavonols via the Algar-Flynn-Oyamada (AFO) reaction: The mechanistic implication”,Tetrahedron2017, 4822-4829.

 

2.      Zhao, W.; Song, S.; Tao, J.; Zhang, J.; Huang, M.; Wang, C.* and Gou, M.*, “Thiol-Functionalized Mesoporous Silica for Effective Trap of Mercury in Rats”, Journal of Nanomaterials, 2016, http://dx.doi.org/10.1155/2016/9758264.

 

3.      Li, Y. P.; Xiong, W.; Wang, C.*, Song, B. and Zhang, G. L., “Synthesis of hexagonal mesoporous silicates with amino groups functionalized on the pore channels by a co-condensation approach”, RSC Advances, 2016, 6, 53991–54000.

 

4.      Fu, X. W.; Yang, Q.; Zhou, Q.; Lin, Q. and Wang, C., “Template-Monomer Interaction in Molecular Imprinting: Is the Strongest the Best? ”, Open Journal of Organic Polymer Materials, 2015, 5, 58-68.

 

5.      Mei, Q. G.; Wang, C.; Yuan, W. C. and Zhang, G. L., “Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates”, Beilstein Journal of Organic Chemistry, 2015, 11, 288–293.

 

6.      Lu, J.; Fu, X. W.; Zhang, G. and Wang, C.*, “b-Cyclodextrin as an efficient catalyst for the one-pot synthesis of tetrahydrobenzo[b]pyran derivatives in water”, Research on Chemical Intermediates, 2016, 42, 417-424.

 

7.      Luo, G. T.; Li, Y. P.; Wang, A.; Lin, Q.; Zhang, G. L. and Wang, C.*, Dummy molecularly imprinted mesoporous silicates for selective adsorption of 2-naphthol”,Open Chemistry, 2015, 756-762.

 

8.      Fu, X. W.; Pu, W. C.;Zhang, G. L. and Wang, C.*, Synthesis of Salicylaldehydes from Phenols via Copper-mediated Duff Reaction”, Research on Chemical Intermediates, 2015, 41:81478158.

 

9.      Mei, Q. G.; Yuan, W. C and Wang, C.*, Progress in the Synthesis of 3-Hydroxyflavones”,Chin. J. Org. Chem. 2015, 35, 7084.

 

10.   Fu, X. W.; Wang, X.; Pu, W. C.; Li, X. R.; Wang, C.*, Synthesis and antitumor activity of calycosin and its derivatives, Chin. J. Syn. Chem., 2015, 23(3), 223-226.

 

11.   Pu, W. C.; Lin, Y.; Zhang, J. S.; Wang, F.; Wang, C.; Zhang, G. L. 3-Arylcoumarins: Synthesis and potent anti-inflammatory activity, Bioorganic & Medicinal Chemistry Letters, 2014, 24, 5432-5434

 

12.   Pu, W. C. Mu, G. M. Zhang, G. L.* and Wang, C. *,“Copper-catalyzed decarboxylative intramolecular CO coupling: Synthesis of 2-arylbenzofuran from 3-arylcoumarin, RSC Advances, 2014, 4, 903-906.

 

13.   Mu, G. M.; Pu, W. C.; Zhou, M.; Liu, Y.; Yang, H. J.; Wang, C.*, “Synthesis of Icaritin”, Chinese Journal of Organic Chemistry, 2013, 33, 1298-1303.

 

14.   Chen, Q. F.; Chen, X. Z.; Li, G. Y.; Wang, C.; Zhang, G. L. “Two new 2-phenylbenzofurans from the bark of Styrax perkinsiae”, Chinese Journal of Natural Medicine, 2012, 10(2), 0092-0097.

 

15.   Liao, X. L.; Xu, X. Y.; Wang, C.; Wu, Z. J.; Fang, D. M.; Zhang, G. L; Luo, S. W. “ESI-IT-MSn and DFT calculation for electron affinities of bimetallic oxovanadium complexes”, Monatshefte fur Chemie, 2011, 142 (11), 1105-1109.

 

16.   Wang, X.; Lv, G. Y.; Yang, L. J.; Wang, F.; Wang, C.*, “Synthesis and Selective Estrogen Receptor Binding Affinity of  7-hydroxylisoflavones”, Chinese Journal of Organic Chemistry, 2011, 8, 1245-1251.

 

17.   Lu, J.; Liao, X. L.; Chen, X. Z.; Wang, C.*, “Asymmetric Inductive Effect of N-Stereogenic Center in Quaternary Ammonium Salts”, Chinese Journal of Organic Chemistry, 2011, 3, 341-345.

 

18.   Pu, W. C.; Wang, F.; Wang, C.*, Bioactivities and Synthetic Methods of 2-Arylbenzo[b]furans, Chinese Journal of Organic Chemistry, 20112155-165.

 

19.   Liao, X. L.; Lin, W. B.; Lu, J.; Wang, C.*, “Oxidative aromatization of Hantzsch 1,4-dihydropyridines by sodium chlorite”, Tetrahedron Letters, 2010, 51, 3859–3861.

 


Students

已指导学生

李云萍  硕士研究生  078001-药物化学  

周强  硕士研究生  078001-药物化学  

沈先艳  硕士研究生  078001-药物化学  

现指导学生

张龙兴  硕士研究生  085238-生物工程  

万顺莉  硕士研究生  078001-药物化学