基本信息
Daisuke Miki  男  博导  中国科学院分子植物科学卓越创新中心
电子邮件: daisukemiki@psc.ac.cn
通信地址: 上海市
邮政编码:

研究领域

植物分子生物学

招生信息

博士1名,硕士2名

招生专业
071007-遗传学
招生方向
植物分子生物学
植物基因编辑
植物表观遗传

教育背景

2000-04--2004-03   Nara Institute of Science and Technology   博士
1998-04--2000-03   Nara Institute of Science and Technology   硕士
1994-04--1998-03   Meiji University   学士
学历
研究生

学位
博士

工作经历

   
工作简历
2020-05~现在, Shanghai Center for Plant Stress Biology, Center of Excellence in Molecular Plant Sciences, CAS, Principal Investigator
2019-01~2020-04,Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, CAS, Principal Investigator
2012-02~2018-12,Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, CAS, Associate Professor
2011-03~2012-02,VIB, Ghent University, Post Doc
2010-04~2011-03,University of California Riverside, Post Doc
2009-04~2010-04,University of California Riverside, TOYOBO BIOFOUNDATION "Long-Term Research Grants"
2007-04~2009-04,University of California Riverside, JSPS Research Fellowships for Yong Scientists
2006-04~2007-04,University of Tokyo, JSPS Research Fellowships for Yong Scientists
2004-04~2006-04,Nara Institute of Science and Technology, COE Post Doctor
2003-04~2004-04,Nara Institute of Science and Technology, Technician
2000-04~2003-04,JSPS Research Fellowships for Yong Scientists, DC1 Nara Institute of Science and Technology, JSPS Research Fellowships for Yong Scientists

教授课程

植物逆境生物学
逆境生物学

专利与奖励

   
奖励信息
(1) 2015 Annual Meeting of The Japanese Society of Epigenetics, 特等奖, 其他, 2015
(2) NAIST COE Summer Camp Meeting, 特等奖, 研究所(学校), 2005
专利成果
( 1 ) 一种无标签用于基因编辑的试剂 组合及其应用, 发明, 2018, 第 2 作者, 专利号: 201810130658.2

出版信息

   
发表论文
(1) Genome-wide distribution and functions of the AAE complex in epigenetic regulation in Arabidopsis, Journal of Integrative Plant Biology, 2021, 第 5 作者
(2) Roles of DEMETER in regulating DNA methylation in vegetative tissues and pathogen resistance, Journal of Integrative Plant Biology, 2021, 通讯作者
(3) Gene targeting in Arabidopsis via an all-in-one strategy that uses a translational enhancer to aid Cas9 expression, Plant Biotechnology Journal, 2020, 通讯作者
(4) DNA demethylases are required for myo-inositol-mediated mutualism between plants and beneficial rhizobacteria, Nature Plants, 2020, 其他(合作组作者)
(5) Gene targeting in Arabidopsis via an all-in-one strategy that uses a translational enhancer to aid Cas9 expression, Plant Biotechnology Journal, 2020, 通讯作者
(6) DNA demethylases are required for myo-inositol-mediated mutualism between plants and beneficial rhizobacteria, Nature Plants, 2020, 其他(合作组作者)
(7) The genome of broomcorn millet, Nature Communications, 2019, 第 3 作者
(8) CRISPR/Cas9-mediated gene targeting in Arabidopsis using sequential transfromation, Nature Communications, 2018, 通讯作者
(9) SAC3B, a central component of the mRNA export complex TREX-2, is required for prevention of epigenetic gene silencing in Arabidopsis., Nucleic Acids Research, 2017, 第 4 作者
(10) A pair of transposon-derived proteins function in a histone acetyltransferase complex for active DNA demethylation, Cell Research, 2017, 第 5 作者
(11) Efficient Generation of diRNAs Requires Components in the Posttranscriptional Gene Silencing Pathway, Scientific Reports, 2017, 通讯作者
(12) The developmental regulator PKL is required to maintain correct DNA methylation patterns at RNA-directed DNA methylation loci, Genome Biology, 2017, 第 6 作者
(13) The methyl-CpG-binding protein MBD7 facilitates active DNA demethylation to limit DNA hyper-methylation and transcriptional gene silencing, Molecular Cell, 2015, 第 5 作者
(14) Involvement of Multiple Gene-Silencing Pathways in a Paramutation-like Phenomenon in Arabidopsis., Cell Reports, 2015, 第 3 作者
(15) Insights into the localization and function of GNOM ARF-GEF at the Golgi apparatus in Arabidopsis thaliana., Plant Cell, 2014, 第 10 作者
(16) Arabidopsis EDM2 promotes IBM1 distal polyadenylation and regulates genome DNA methylation patterns, Proc. Natl. Acad. Sci. USA, 2014, 第 5 作者
(17) Regulation of Active DNA Demethylation by An α-Crystallin Domain Protein in Arabidopsis., Molecular Cell, 2014, 第 1 作者
(18) Overproduction of stomatal lineage cells in Arabidopsis mutants defective in active DNA demethylation, Nature Communications, 2014, 第 2 作者
(19) A Pre-mRNA-Splicing Factor Is Required for RNA-Directed DNA Methylation in Arabidopsis., PLOS Genetics, 2013, 第 2 作者
(20) A Histone Acetyltransferase Regulates Active DNA Demethylation in Arabidopsis., Science, 2012, 第 1 作者
(21) Sulfamethazine Suppresses Epigenetic Silencing in Arabidopsis by Impairing Folate Synthesis., Plant Cell, 2012, 第 3 作者
(22) A DNA 3’-phosphatase functions in active DNA demethylation in Arabidopsis., Molecular Cell, 2012, 第 1 作者
(23) DNA replication factor C1 mediates genomic stability and transcriptional gene silencing in Arabidopsis, Plant Cell, 2010, 第 3 作者
(24) An RNA polymerase II- and AGO4-associated protein acts in RNA-directed DNA methylation, Nature, 2010, 第 10 作者
(25) Knock-down of OsDCL2 in Rice Negatively Affects Maintenance of the Endogenous dsRNA Virus, Oryza sativa Endornavirus, Plant and Cell Physiology,, 2010, 第 5 作者
(26) Analysis of the Rac/Rop Small GTPase Family in Rice: Expression, Subcellular Localization and Role in Disease Resistance., Plant and Cell Physiology, 2010, 第 4 作者
(27) ROS3, an RNA-binding protein required for DNA demethylation in Arabidopsis., Nature, 2008, 第 4 作者
(28) De novo DNA methylation induced by siRNA targeted to endogenous transcribed sequences is gene-specific and OsMet1-independent in rice., The Plant Journal, 2008, 第 1 作者
(29) Small interfering RNA (siRNA) targeting of endogenous promoters induces DNA methylation, but not necessarily gene silencing, in rice., The Plant Journal, 2008, 第 2 作者
(30) RNA silencing of single and multiple members in a gene family of rice., Plant Physiology, 2005, 第 1 作者
(31) RNAi-mediated silencing of OsGEN-L (OsGEN-like), a new member of the RAD2/XPG nuclease family, causes male sterility by defect of microspore development in rice., Plant and Cell Physiology, 2005, 第 2 作者
(32) Simple RNAi vectors for stable and transient suppression of gene function in rice., Plant and Cell Physiology, 2004, 第 1 作者
(33) 

科研活动

   
科研项目
( 1 ) 植物逆境生物学研究, 参与, 市地级, 2012-01--2025-12
( 2 ) DNA甲基化和分化控制基因影响江淮地区籼稻碱基编辑的分子机制及应用, 参与, 国家级, 2020-01--2024-12
( 3 ) 作物高效精确的基因打靶, 主持, 省级, 2020-07--2023-06

指导学生

已指导学生

彭方楠  硕士研究生  071007-遗传学  

现指导学生

曾文婕  博士研究生  071007-遗传学  

王睿  硕士研究生  071007-遗传学  

宋明磊  博士研究生  071007-遗传学  

朱巧巧  博士研究生  071007-遗传学  

王应英  博士研究生  071007-遗传学  

李敬  硕士研究生  071007-遗传学  

孔大莉  硕士研究生  071010-生物化学与分子生物学  

张蕾  硕士研究生  071010-生物化学与分子生物学  

郝建楠  硕士研究生  071007-遗传学  

黄文嘉  硕士研究生  071007-遗传学  

张学宁  博士研究生  071007-遗传学  

何雨欣  博士研究生  071007-遗传学  

姚瑶  博士研究生  071007-遗传学  

黄博宇  博士研究生  071007-遗传学  

张燕  博士研究生  071007-遗传学  

柯永平  硕士研究生  071007-遗传学  

钟达庭  硕士研究生  071010-生物化学与分子生物学  

孔喆  硕士研究生  071010-生物化学与分子生物学