1001J6-再生医学

干细胞与器官再造

2009-09--2012-06   东北农业大学   博士研究生/博士学位
2006-09--2009-06   甘肃农业大学   硕士研究生/硕士学位
2002-09--2006-06   东北农业大学   本科/学士学位

   

2020-07~现在, 中国科学院动物研究所, 副研究员
2014-06~2020-07,中国科学院动物研究所, 助理研究员
2012-07~2014-06,中国科学院动物研究所, 博士后
2009-09~2012-06,东北农业大学, 博士研究生/博士学位
2006-09~2009-06,甘肃农业大学, 硕士研究生/硕士学位
2002-09~2006-06,东北农业大学, 本科/学士学位

2023-01-01-今,中国细胞生物学学会 科普工作委员会, 主任委员
2020-12-01-今,《实验动物科学》编委会, 委员

   

（1） Functional mouse hepatocytes derived from interspecies chimeric livers effectively mitigate chronic liver fibrosis, Stem Cell Reports, 2024, 
（2） Live-cell imaging reveals redox metabolic reprogramming during zygotic genome activation, JOURNAL OF CELLULAR PHYSIOLOGY, 2023, 第 3 作者
（3） TRANSCRIPTOME AND DNA METHYLATION PROFILES OF MOUSE FETUS AND PLACENTA GENERATED BY ROUND SPERMATID INJECTION, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 第 4 作者
（4） Clinical analysis of human umbilical cord mesenchymal stem cell allotransplantation in patients with premature ovarian insufficiency, CELL PROLIFERATION, 2020, 第 8 作者
（5） Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs, PROTEIN & CELL, 2020, 第 9 作者
（6） Human umbilical cord mesenchymal stem cells restore the ovarian metabolome and rescue premature ovarian insufficiency in mice, STEM CELL RESEARCH & THERAPY, 2020, 第 8 作者
（7） Phase 1 trial for treatment of COVID-19 patients with pulmonary fibrosis using hESC-IMRCs, CELL PROLIFERATION, 2020, 第 5 作者
（8） Derivation of Mouse Haploid Trophoblast Stem Cells, CELL REPORTS, 2019, 第 3 作者
（9） Sox2 and Klf4 as the Functional Core in Pluripotency Induction without Exogenous Oct4, CELL REPORTS, 2019, 第 5 作者
（10） Generation of rat-mouse chimeras by introducing single cells of rat inner cell masses into mouse blastocysts, Generation of rat-mouse chimeras by introducing single cells of rat inner cell masses into mouse blastocysts, Journal of Genetics and Genomics, 2018, 第 1 作者
（11） Individual blastomeres of 4-and 8-cell embryos have ability to develop into a full organism in mouse, JOURNAL OF GENETICS AND GENOMICS, 2018, 第 2 作者
（12） Repurposing CRISPR-Cas12b for mammalian genome engineering, CELLDISCOVERY, 2018, 第 7 作者
（13） Mitochondrially produced ATP affects stem cell pluripotency via ActI6a-mediated histone acetylation, FASEB JOURNAL, 2018, 第 7 作者
（14） Generation of rat-mouse chimeras by introducing single cells of rat inner cell masses into mouse blastocysts, JOURNAL OF GENETICS AND GENOMICS, 2018, 第 1 作者
（15） Human embryonic stem cells contribute to embryonic and extraembryonic lineages in mouse embryos upon inhibition of apoptosis, CELL RESEARCH, 2018, 第 2 作者
（16） Overexpression of Stella Improves the Efficiency of Nuclear Transfer Reprogramming, JOURNAL OF GENETICS AND GENOMICS, 2017, 第 8 作者
（17） Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-Wide Genetic Screening, CELL REPORTS, 2017, 第 9 作者
（18） Rat Embryonic Stem Cells Produce Fertile Offspring Through Tetraploid Complementation, PNAS, 2017, 第 1 作者
（19） Rat embryonic stem cells produce fertile offspring through tetraploid complementation, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 第 1 作者
（20） Efficient Production of Fluorescent Transgenic Rats Using the piggyBac Transposon, SCIENTIFIC REPORTS, 2016, 第 1 作者
（21） Genetic Modification and Screening in Rat Using Haploid Embryonic Stem Cells, CELL STEM CELL, 2014, 第 3 作者
（22） Parthenogenetic Haploid Embryonic Stem Cells Produce Fertile Mice, CELL RESEARCH, 2013, 第 11 作者
（23） Simultaneous Generation and Germline Transmission of Multiple Gene Mutations in Rat Using CRISPR-Cas Systems, NATURE BIOTECHNOLOGY, 2013, 
（24） Generation of Transgenic Rats through Induced Pluripotent Stem Cells*, JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 第 2 作者
（25） Generation of Tripotent Neural Progenitor Cells from Rat Embryonic Stem Cells, JOURNAL OF GENETICS AND GENOMICS, 2012, 第 3 作者
（26） Androgenetic haploid embryonic stem cells produce live transgenic mice, NATURE, 2012, 
（27） Derivation of Germline Competent Rat Embryonic Stem Cells from DA Rats, JOURNAL OF GENETICS AND GENOMICS, 2012, 第 1 作者
（28） Induced Pluripotent Stem-Induced Cells Show Better Constitutive Heterochromatin Remodeling and Developmental Potential After Nuclear Transfer Than Their Parental Cells, STEM CELLS AND DEVELOPMENT, 2012, 第 7 作者

   

（ 1 ） 空间低敏感小鼠模型建立及微重力影响胚胎发育机制, 参与, 国家任务, 2021-12--2026-11