基本信息
海军  男  博导  中国科学院兰州化学物理研究所
电子邮件: haijun@licp.cas.cn
通信地址: 甘肃省兰州市城关区天水中路18号
邮政编码:

招生信息

   
招生专业
070302-分析化学
招生方向
药物分析化学,生命分析化学

教育背景

2016-10--2019-05   兰州大学   师资博士后
2012-01--2016-05   Université Paris Diderot - Paris VII   博士

工作经历

   
工作简历
2023-05~现在, 中国科学院兰州化学物理研究所, 特聘青年研究员
2019-01~2023-03,兰州大学, 青年研究员

专利与奖励

   
专利成果
[1] 汪宝堆, 李欣悦, 张华, 海军, 高宁双, 常新月. 一种近红外二区甲基汞离子检测探针及其制备方法和应用. CN: CN115057875A, 2022-09-16.
[2] 汪宝堆, 孟跟平, 海军, 胡国文, 王智勤. 一种耐水凹凸棒-钙钛矿复合荧光粉的制备方法. CN: CN114656953A, 2022-06-24.
[3] 汪宝堆, 常新月, 张华, 梁琨, 海军. 一种超灵敏检测水中Cr(Ⅵ)离子敏感膜及其制备方法. CN: CN113667471A, 2021-11-19.
[4] 汪宝堆, 孟跟平, 海军, 胡国文, 赵永青. 超小尺寸纳米铜粉的宏量制备方法. CN: CN113600829A, 2021-11-05.
[5] 汪宝堆, 海军, 陈凤娟. 一种金属配合物、一种金属配合物的制备方法和应用. CN: CN109851683A, 2019-06-07.

出版信息

   
发表论文
[1] Zhang, Jinlong, Jing, Quan, Yuan, Longlong, Zhou, Xianhui, Di, Duolong, Li, Jinyao, Pei, Dong, Fan, Zhongxiong, Hai, Jun. NIR-triggered programmable nanomotor with H2S and NO generation for cascading oncotherapy by three-pronged reinforcing ICD. MATERIALS TODAY BIO[J]. 2025, 第 9 作者  通讯作者  31: 101540, http://dx.doi.org/10.1016/j.mtbio.2025.101540.
[2] Li, Zhige, Li, Ziyuan, Wang, Jiao, Liao, Lingzi, Li, Xinjie, Zhang, Zhidong, Yang, Xin, Yu, Xiangxue, Fan, Baoquan, Li, Bo, Hai, Jun, Zhang, Baoping. Binary Doping of Strontium-Magnesium to Bioactive Glasses to Enhance Antibacterial and Osteogenic Effects. ACS OMEGA[J]. 2024, 第 11 作者  通讯作者  10(1): 215-229, http://dx.doi.org/10.1021/acsomega.4c04898.
[3] Xu, Jingyuan, Wang, Yun, Wang, Dan, Hai, Jun, Ji, Yibing, Li, Ruijun. Co/Mn-Doped Oxide Nanosheets with Dual Enzyme-Like Activity for Early Visual Diagnosis of Pheochromocytoma. ACS APPLIED NANO MATERIALS[J]. 2024, 第 4 作者  通讯作者  7(14): 16749-16757, http://dx.doi.org/10.1021/acsanm.4c02807.
[4] Wang, Yun, Wang, Dan, Mu, Qixuan, Zhai, Yanke, Hai, Jun, Ji, Yibing, Li, Ruijun. Exploring of laccase-like nanozyme and membrane filters for efficient removal of tetracycline hydrochloride. CHEMICAL ENGINEERING JOURNAL[J]. 2024, 第 5 作者  通讯作者  502: http://dx.doi.org/10.1016/j.cej.2024.158021.
[5] Zhang, Qianqian, Gao, Shuting, Li, Bo, Li, Qian, Li, Xinjie, Cheng, Jingyang, Peng, Zhenjun, Liang, Jun, Zhang, Kailiang, Hai, Jun, Zhang, Baoping. Lithium-Doped Titanium Dioxide-Based Multilayer Hierarchical Structure for Accelerating Nerve-Induced Bone Regeneration. ACS APPLIED MATERIALS & INTERFACES[J]. 2024, 第 10 作者  通讯作者  16(18): 22887-22899, http://dx.doi.org/10.1021/acsami.4c01520.
[6] Hu, Jing, Wang, Tianmiao, Xu, Jingyuan, Hai, Jun, Ji, Yibing, Li, Ruijun. Dual-emission red carbon dots for ATP real-time monitoring and quantification to reveal drug and cancer effects on lysosomes. TALANTA[J]. 2024, 第 4 作者  通讯作者  280: http://dx.doi.org/10.1016/j.talanta.2024.126671.
[7] Li, Xinxin, Wu, Ting, Zhang, Zefan, Liu, Sha, Cui, Hongmei, Fan, Zhongxiong, Wang, Baodui, Hai, Jun. Tumor microenvironment activated nanoreactors for chemiluminescence imaging-guided simultaneous elimination of breast tumors and tumor-resident intracellular pathogens. CHEMICAL ENGINEERING JOURNAL[J]. 2023, 第 8 作者  通讯作者  453: http://dx.doi.org/10.1016/j.cej.2022.139939.
[8] Bi, Xuehan, Lv, Xiao, Mu, Xijiao, Hai, Jun, Cao, Jing, Yang, Yongxiu. Molecular Dipole Modulation of Porphyrins to Enhance Photocatalytic Oxidation Activity for Inactivation of Intracellular Bacteria. ACS BIOMATERIALS SCIENCE & ENGINEERING. 2023, 第 4 作者  通讯作者  http://dx.doi.org/10.1021/acsbiomaterials.2c01219.
[9] Sun, Panpan, Chen, HaiChao, Lu, Siyu, Hai, Jun, Guo, Wenting, Jing, YuHong, Wang, Baodui. Simultaneous Sensing of H2S and ATP with a Two-Photon Fluorescent Probe in Alzheimer's Disease: toward Understanding Why H2S Regulates Glutamate-Induced ATP Dysregulation. ANALYTICAL CHEMISTRY. 2022, 第 4 作者http://dx.doi.org/10.1021/acs.analchem.2c01850.
[10] Meng, Genping, Mu, Xijiao, Zhen, Liping, Hai, Jun, Zhang, Zefan, Hao, Tianzhi, Lu, Siyu, Wang, Aiqin, Wang, Baodui. Confinement and passivation of perovskite quantum dots in porous natural palygorskite toward an efficient and ultrastable light-harvesting system in water. CHEMICAL SCIENCE[J]. 2022, 第 4 作者13(47): 14141-14150, http://dx.doi.org/10.1039/d2sc05220b.
[11] Sun, Dina, Meng, Gengping, Sun, Shihao, Guo, Wenting, Hai, Jun, Su, Junxia, Song, Yanxia, Chen, Fengjuan, Wang, Baodui. Silk nanofibers-ZIF hybrid membrane with improved treatment efficiency and highly enhanced water permeability for excellent removal of multiple pollutants from water. ENVIRONMENTAL SCIENCE-NANO[J]. 2021, 第 5 作者  通讯作者  8(11): 3408-3420, http://dx.doi.org/10.1039/d1en00798j.
[12] Fu, Xu, Yin, Wen, Shi, Dao, Yang, Yifan, He, Suisui, Hai, Jun, Hou, Zhenqing, Fan, Zhongxiong, Zhang, Dekui. Shuttle-Shape Carrier-Free Platinum-Coordinated Nanoreactors with O-2 Self-Supply and ROS Augment for Enhanced Phototherapy of Hypoxic Tumor. ACS APPLIED MATERIALS & INTERFACES[J]. 2021, 第 6 作者13(28): 32690-32702, http://dx.doi.org/10.1021/acsami.1c06668.
[13] Meng, Genping, Zhen, Liping, Sun, Shihao, Hai, Jun, Zhang, Zefan, Sun, Dina, Liu, Qiang, Wang, Baodui. Confining perovskite quantum dots in the pores of a covalent-organic framework: quantum confinement- and passivation-enhanced light-harvesting and photocatalysis. JOURNAL OF MATERIALS CHEMISTRY A[J]. 2021, 第 4 作者  通讯作者  9(43): 24365-24373, http://dx.doi.org/10.1039/d1ta07733c.
[14] Sun, Panpan, Jia, Le, Hai, Jun, Lu, Siyu, Chen, Fengjuan, Liang, Kun, Sun, Shihao, Liu, Hanwen, Fu, Xu, Zhu, Yanhong, Wang, Baodui. Tumor Microenvironment-"AND" Near-Infrared Light-Activated Coordination Polymer Nanoprodrug for On-Demand CO-Sensitized Synergistic Cancer Therapy. ADVANCED HEALTHCARE MATERIALS[J]. 2021, 第 3 作者10(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000597833400001.
[15] Liu, Sha, Chai, Jian, Sun, Shihao, Zhang, Lang, Yang, Jiayue, Fu, Xu, Hai, Jun, Jing, YuHong, Wang, Baodui. Site-Selective Photosynthesis of Ag-AgCl@Au Nanomushrooms for NIR-II Light-Driven O-2(-) and O2(center dot-)-Evolving Synergistic Photothermal Therapy against Deep Hypoxic Tumors. ACS APPLIED MATERIALS & INTERFACES[J]. 2021, 第 7 作者  通讯作者  13(39): 46451-46463, http://dx.doi.org/10.1021/acsami.1c16999.
[16] Li, Xinyue, Lu, Siyu, Mu, Xijiao, Li, Tianrong, Sun, Shihao, Zhao, Yang, Hai, Jun, Wang, Baodui. Red-light-responsive coordination polymers nanorods: New strategy for ultrasensitive photothermal detection of targeted cancer cells. BIOSENSORS & BIOELECTRONICS[J]. 2021, 第 7 作者  通讯作者  190: http://dx.doi.org/10.1016/j.bios.2021.113417.
[17] Liu, Sha, Lu, Siyu, Sun, Shihao, Hai, Jun, Meng, Genping, Wang, Baodui. NIR II Light-Response Au Nanoframes: Amplification of a Pressure- and Temperature-Sensing Strategy for Portable Detection and Photothermal Therapy of Cancer Cells. ANALYTICAL CHEMISTRY[J]. 2021, 第 4 作者  通讯作者  93(42): 14307-14316, http://dx.doi.org/10.1021/acs.analchem.1c03486.
[18] Zhong, Kaipeng, Lu, Siyu, Guo, Wenting, Su, Junxia, Sun, Shihao, Hai, Jun, Chen, Fenjuan, Wang, Aiqin, Wang, Baodui. Embedding CsPbBr3 quantum dots into a pillar5arene-based supramolecular self-assembly for an efficient photocatalytic cross-coupling hydrogen evolution reaction. JOURNAL OF MATERIALS CHEMISTRY A[J]. 2021, 第 6 作者9(16): 10180-10185, http://dx.doi.org/10.1039/d1ta00483b.
[19] Song, Yanxia, Lu, Siyu, Hai, Jun, Liang, Kun, Sun, Shihao, Meng, Genping, Wang, Baodui. Nitrogen-Doped Chiral CuO/CoO Nanofibers: An Enhanced Electrochemiluminescence Sensing Strategy for Detection of 3,4-Dihydroxy-Phenylalanine Enantiomers. ANALYTICAL CHEMISTRY[J]. 2021, 第 3 作者93(33): 11470-11478, http://dx.doi.org/10.1021/acs.analchem.1c01497.
[20] Song, Yanxia, Lu, Siyu, Sun, Shihao, Guo, Wenting, Su, Junxia, Meng, Genping, Hai, Jun, Wang, Baodui. A fluorometric and optical signal dual-readout detection of alkaline phosphatase activity in living cells based on ATP-mediated porphyrin MOFs. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2021, 第 7 作者  通讯作者  342: http://dx.doi.org/10.1016/j.snb.2021.130017.
[21] Zhang, Ruichao, Xu, Qi, Bai, Suo, Hai, Jun, Cheng, Li, Xu, Guoqiang, Qin, Yong. Enhancing the filtration efficiency and wearing time of disposable surgical masks using TENG technology. NANO ENERGY[J]. 2021, 第 4 作者79: http://dx.doi.org/10.1016/j.nanoen.2020.105434.
[22] Sun, Panpan, Hai, Jun, Sun, Shihao, Lu, Siyu, Liu, Sha, Liu, Hanwen, Chen, Fengjuan, Wang, Baodui. Aqueous stable Pd nanoparticles/covalent organic framework nanocomposite: an efficient nanoenzyme for colorimetric detection and multicolor imaging of cancer cells. NANOSCALE[J]. 2020, 第 2 作者12(2): 825-831, https://www.webofscience.com/wos/woscc/full-record/WOS:000507642000030.
[23] 李天荣, 苏军霞, 陈凤娟, 李华, 海军, 梁永民, 汪宝堆. 碳点的合成及对锰离子的比色检测--推荐一个大学化学综合实验. 大学化学[J]. 2020, 第 5 作者35(12): 206-211, http://lib.cqvip.com/Qikan/Article/Detail?id=7103773916.
[24] Su, Junxia, Lu, Siyu, Hai, Jun, Liang, Kun, Li, Tianrong, Sun, Shihao, Chen, Fengjuan, Yang, Zhengyin, Wang, Baodui. Confining Carbon Dots in Porous Wood: The Singlet Oxygen Enhancement Strategy for Photothermal Signal-Amplified Detection of Mn2+. ACS SUSTAINABLE CHEMISTRY & ENGINEERING[J]. 2020, 第 3 作者8(48): 17687-17696, https://www.webofscience.com/wos/woscc/full-record/WOS:000599195300009.
[25] 汪宝堆, 李天荣, 海军, 梁永民, 杨正银. 金纳米粒子的制备及在汞离子检测中的应用——推荐一个分析化学综合实验. 大学化学[J]. 2020, 第 3 作者35(9): 103-109, http://lib.cqvip.com/Qikan/Article/Detail?id=7103098760.
[26] He, Suisui, Lu, Siyu, Liu, Sha, Li, Tianrong, Li, Jieling, Sun, Shihao, Liu, Meilin, Liang, Kun, Fu, Xu, Chen, Fengjuan, Meng, Genping, Zhang, Lang, Hai, Jun, Wang, Baodui. Spatiotemporally controlled O(2)and singlet oxygen self-sufficient nanophotosensitizers enable thein vivohigh-yield synthesis of drugs and efficient hypoxic tumor therapy. CHEMICAL SCIENCE[J]. 2020, 第 13 作者  通讯作者  11(33): 8817-8827, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163376/.
[27] Hai, Jun, Wang, Hao, Sun, Panpan, Li, Tianrong, Lu, Siyu, Zhao, Yang, Wang, Baodui. Smart Responsive Luminescent Aptamer-Functionalized Covalent Organic Framework Hydrogel for High -Resolution Visualization and Security Protection of Latent Fingerprints. ACS APPLIED MATERIALS & INTERFACES[J]. 2019, 第 1 作者11(47): 44664-44672, http://dx.doi.org/10.1021/acsami.9b18251.
[28] Hai, Jun, Tan, Xuan, Yang, Sheng, Chen, Fengjuan, Li, Tianrong, Yang, Xiangliang, Zhu, Yanhong, Wang, Baodui. Facile preparation of a Ca(II) carboxymethyl cellulose complex with enhanced calcium bioavailability for treatment of osteoporosis. DALTONTRANSACTIONS[J]. 2019, 第 1 作者48(17): 5735-5740, https://www.webofscience.com/wos/woscc/full-record/WOS:000466327900030.
[29] He, Suisui, Hai, Jun, Sun, Shihao, Lu, Siyu, Wang, Baodui. Palladium Coordination Polymers Nanosheets: New Strategy for Sensitive Photothermal Detection of H2S. ANALYTICAL CHEMISTRY[J]. 2019, 第 2 作者91(16): 10823-10829, https://www.webofscience.com/wos/woscc/full-record/WOS:000482545300065.
[30] Li, Chaorui, Hai, Jun, Fan, Long, Li, Siliang, Wang, Baodui, Yang, Zhengyin. Amplified colorimetric detection of Ag+ based on Ag+-triggered peroxidase-like catalytic activity of ZIF-8/GO nanosheets. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2019, 第 2 作者284: 213-219, http://dx.doi.org/10.1016/j.snb.2018.12.137.
[31] Hai, Jun, Zeng, Xiaofan, Zhu, Yanhong, Wang, Baodui. Anions reversibly responsive luminescent nanocellulose hydrogels for cancer spheroids culture and release. BIOMATERIALS[J]. 2019, 第 1 作者194: 161-170, http://dx.doi.org/10.1016/j.biomaterials.2018.12.016.
[32] Hai, Jun, Li, Tianrong, Su, Junxia, Liu, Weisheng, Ju, Yanmin, Wang, Baodui, Hou, Yanglong. Reversible Response of Luminescent Terbium(III)-Nanocellulose Hydrogels to Anions for Latent Fingerprint Detection and Encryption. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2018, 第 1 作者57(23): 6786-6790, http://dx.doi.org/10.1002/anie.201800119.
[33] He, Suisui, Hai, Jun, Li, Tianrong, Liu, Sha, Chen, Fengjuan, Wang, Baodui. Photochemical strategies for the green synthesis of ultrathin Au nanosheets using photoinduced free radical generation and their catalytic properties. NANOSCALE[J]. 2018, 第 2 作者10(39): 18805-18811, https://www.webofscience.com/wos/woscc/full-record/WOS:000448421100043.
[34] Wang, Zhiyi, Hai, Jun, Li, Tianrong, Ding, Erli, He, Jianxin, Wang, Baodui. Pressure and Fluorescence Dual Signal Readout CuO-NiO/C Heterojunction Nanofibers-Based Nanoplatform for Imaging and Detection of Target Cancer Cells in Blood. ACS SUSTAINABLE CHEMISTRY & ENGINEERING[J]. 2018, 第 2 作者6(8): 9921-9929, https://www.webofscience.com/wos/woscc/full-record/WOS:000441475500046.
[35] Wang, Zhiyi, Zhang, Jie, Wang, Hao, Hai, Jun, Wang, Baodui. Se Atom-Induced Synthesis of Concave Spherical Fe3O4@Cu2O Nanocrystals for Highly Efficient MRI-SERS Imaging-Guided NIR Photothermal Therapy. PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION[J]. 2018, 第 4 作者35(11): https://www.webofscience.com/wos/woscc/full-record/WOS:000451114200004.
[36] Hai, Jun, Chen, Fengjuan, Su, Junxia, Xu, Fu, Wang, Baodui. Porous Wood Members-Based Amplified Colorimetric Sensor for Hg2+ Detection through Hg2+-Triggered Methylene Blue Reduction Reactions. ANALYTICAL CHEMISTRY[J]. 2018, 第 1 作者90(7): 4909-4915, http://dx.doi.org/10.1021/acs.analchem.8b00710.
[37] Wang, Jianrong, Gong, Xue, Hai, Jun, Li, Tianrong. Synthesis of silver-hydroxyapatite composite with improved antibacterial properties. VACUUM[J]. 2018, 第 3 作者152: 132-137, http://dx.doi.org/10.1016/j.vacuum.2018.03.015.
[38] Hai, J, Piraux, H, Mazario, E, Volatron, J, HaDuong, N T, Decorse, P, Lomas, J S, Verbeke, P, Ammar, S, Wilhelm, C, Chahine, J M El Hage, Hemadi, M. Maghemite nanoparticles coated with human serum albumin: combining targeting by the iron-acquisition pathway and potential in photothermal therapies. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2017, 5(17): 3154-3162, https://www.webofscience.com/wos/woscc/full-record/WOS:000400501900009.
[39] Zhi, Lihua, Zeng, Xiaofan, Wang, Hao, Hai, Jun, Yang, Xiangliang, Wang, Baodui, Zhu, Yanhong. Photocatalysis-Based Nanoprobes Using Noble Metal-Semiconductor Heterostructure for Visible Light-Driven in Vivo Detection of Mercury. ANALYTICAL CHEMISTRY[J]. 2017, 第 4 作者89(14): 7649-7658, https://www.webofscience.com/wos/woscc/full-record/WOS:000406085300049.
[40] Hai, Jun, Li, Hua, Zhao, Yang, Chen, Fengjuan, Peng, Yong, Wang, Baodui. Designing of blue, green, and red CsPbX3 perovskitecodoped flexible films with water resistant property and elimination of anion-exchange for tunable white light emission. CHEMICAL COMMUNICATIONS[J]. 2017, 第 1 作者53(39): 5400-5403, https://www.webofscience.com/wos/woscc/full-record/WOS:000401118400010.
[41] Chen, Gaosong, Hai, Jun, Wang, Hao, Liu, Weisheng, Chen, Fengjuan, Wang, Baodui. Gold nanoparticles and the corresponding filter membrane as chemosensors and adsorbents for dual signal amplification detection and fast removal of mercury(II). NANOSCALE[J]. 2017, 第 2 作者9(9): 3315-3321, http://dx.doi.org/10.1039/c6nr09638g.
[42] Hai, Jun, Serradji, Nawal, Mouton, Ludovic, Redeker, Virginie, Cornu, David, Chahine, JeanMichel El Hage, Verbeke, Philippe, Hemadi, Miryana. Targeted Delivery of Amoxicillin to C. trachomatis by the Transferrin Iron Acquisition Pathway. PLOS ONE[J]. 2016, 第 1 作者11(2): https://doaj.org/article/bb74fbd1ed944eb7a377c6286c4c9da8.
[43] Wang, Baodui, Hai, Jun, Wang, Qin, Li, Tianrong, Yang, Zhengyin. Coupling of Luminescent Terbium Complexes to Fe3O4 Nanoparticles for Imaging Applications. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2011, 第 2 作者50(13): 3063-3066, https://www.webofscience.com/wos/woscc/full-record/WOS:000288333600035.
[44] Qifeng Bai, Yulin Shen, Xiaojun Yao, Fang Wang, Yuping Du, Qin Wang, Nengzhi Jin, Jun Hai, Tiejun Hu, Jinbo Yang. Modeling a New Water Channel That Allows SET9 to Dimethylate p53. PLOS ONE[J]. 2011, 第 8 作者6(5): http://dx.doi.org/10.1371/journal.pone.0019856.
[45] Wang, Baodui, Hai, Jun, Liu, Zengchen, Wang, Qin, Yang, Zhengyin, Sun, Shouheng. Selective Detection of Iron(III) by Rhodamine-Modified Fe3O4 Nanoparticles. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2010, 第 2 作者49(27): 4576-4579, https://www.webofscience.com/wos/woscc/full-record/WOS:000279508500006.
[46] 高笑菲, 海军, 杜宇平, 王勤, 惠新平. TIP-6通过诱导细胞自噬抑制培养的HepG2细胞和正常肝细胞增殖. 细胞与分子免疫学杂志[J]. 2009, 第 2 作者883-886, http://lib.cqvip.com/Qikan/Article/Detail?id=31758466.
[47] Wang, Baodui, Yang, ZhengYin, Lue, Minghua, Hai, Jun, Wang, Qin, Chen, ZhongNing. Synthesis, characterization, cytotoxic activity and DNA binding Ni(II) complex with the 6-hydroxy chromone-3-carbaldehyde thiosemicarbazone. JOURNAL OF ORGANOMETALLIC CHEMISTRY[J]. 2009, 第 4 作者694(25): 4069-4075, http://dx.doi.org/10.1016/j.jorganchem.2009.08.024.

科研活动

   
科研项目
( 1 ) 新型敏感材料精准合成及其检测技术方法研发, 参与, 国家任务, 2020-11--2024-10
( 2 ) 面向重大疾病标志物精准分析新方法和新技术研发及应用, 负责人, 研究所自主部署, 2023-05--2028-05