General
Wen-xiang CHENG
Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS)
E-mail: wx.cheng@siat.ac.cn
Address: 1068 Xueyuan Avenue, Nanshan District, Shenzhen, Guangdong, P. R. China
Postal Code: 518055
Research Areas
Inflammatory bone disease, drug development, osteoclastic function, protein structure
Education
2016-09--2020-07 University of Chinese Academy of Sciences PhD
2004-09-07-07 Shantou University, Master
Experience
Work Experience
2011-01~Now, Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Associate Researcher
2007-07~2011-01, AstraZeneca China Innovation Centre, Assistant Scientist
Publications
（1） Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis, FRONTIERS IN PHARMACOLOGY, 2021
（2） Treatment of collagen-induced arthritis rat model by using Notch signalling inhibitor, JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021
（3） The effect and mechanism of QufengZhitong capsule for the treatment of osteoarthritis in a rat model, JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021
（4） Cinnamaldehyde Inhibits Inflammation of Human Synoviocyte Cells Through Regulation of Jak/Stat Pathway and Ameliorates Collagen-Induced Arthritis in Rats, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2020
（6） Downregulation of Hypoxia-Inducible Factor-1 alpha by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats, MOLECULAR THERAPY-NUCLEIC ACIDS, 2020
（7） Qu Feng Zhi Tong capsule increases mechanical properties of cortical bone in ovariectomised rats, JOURNAL OF ORTHOPAEDIC TRANSLATION, 2020
（8） Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway, JOURNAL OF ORTHOPAEDIC TRANSLATION, 2020
（9） THP-1源巨噬细胞上清液对类风湿性关节炎成纤维细胞和血管内皮细胞的作用, The Effect of Supernatant-Derived from THP-1 Macrophage on Rheumatoid Arthritis Fibroblasts and Vascular Endothelial Cells in Vitro, 集成技术
（10） Characterization and validation of somatic mutation spectrum to reveal heterogeneity in gastric cancer by single cell sequencing, SCIENCE BULLETIN, 2019
（2） Treatment of collagen-induced arthritis rat model by using Notch signalling inhibitor, JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021
（3） The effect and mechanism of QufengZhitong capsule for the treatment of osteoarthritis in a rat model, JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021
（4） Cinnamaldehyde Inhibits Inflammation of Human Synoviocyte Cells Through Regulation of Jak/Stat Pathway and Ameliorates Collagen-Induced Arthritis in Rats, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2020
（6） Downregulation of Hypoxia-Inducible Factor-1 alpha by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats, MOLECULAR THERAPY-NUCLEIC ACIDS, 2020
（7） Qu Feng Zhi Tong capsule increases mechanical properties of cortical bone in ovariectomised rats, JOURNAL OF ORTHOPAEDIC TRANSLATION, 2020
（8） Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway, JOURNAL OF ORTHOPAEDIC TRANSLATION, 2020
（9） THP-1源巨噬细胞上清液对类风湿性关节炎成纤维细胞和血管内皮细胞的作用, The Effect of Supernatant-Derived from THP-1 Macrophage on Rheumatoid Arthritis Fibroblasts and Vascular Endothelial Cells in Vitro, 集成技术
（10） Characterization and validation of somatic mutation spectrum to reveal heterogeneity in gastric cancer by single cell sequencing, SCIENCE BULLETIN, 2019