基本信息
袁成前 男 硕导 中国科学院过程工程研究所
电子邮件: cqyuan@ipe.ac.cn
通信地址: 北京市海淀区中关村北二街1号
邮政编码: 100190
电子邮件: cqyuan@ipe.ac.cn
通信地址: 北京市海淀区中关村北二街1号
邮政编码: 100190
招生信息
招生专业
081703-生物化工080502-材料学
招生方向
生物分子自组装生物分子玻璃
工作经历
工作简历
2024-10~现在, 中国科学院过程工程研究所, 项目研究员2022-12~2023-11,特拉维夫大学, 访问学者2020-08~2024-10,中国科学院过程工程研究所, 副研究员2018-12~2020-08,中国科学院过程工程研究所, 助理研究员2016-08~2018-11,中国科学院过程工程研究所, 博士后
专利与奖励
奖励信息
(1) 化学所杰士杰奖学金, 一等奖, 研究所(学校), 2016(2) 2014年山东高等学校优秀科研成果奖, 三等奖, 省级, 2014(3) 研究生国家奖学金, 特等奖, 部委级, 2012
专利成果
( 1 ) 一种含黄酮和免疫调节肽的组合制剂、其制备方法及应用, 2022, 第 5 作者, 专利号: CN111317822B( 2 ) 环肽玻璃及含有环肽的药物组合物玻璃, 2022, 第 3 作者, 专利号: CN114014908A( 3 ) 一种基于氨基酸的玻璃、其制备方法及应用, 2021, 第 3 作者, 专利号: CN113754556A( 4 ) 一种活性寡肽水凝胶材料及其制备方法和应用, 2021, 第 4 作者, 专利号: CN112957476A( 5 ) 一种胶体活性银及其制备方法和应用, 2021, 第 4 作者, 专利号: CN112933111A( 6 ) 一种碱性电解水增效液及其制备方法和应用, 2021, 第 5 作者, 专利号: CN112889839A( 7 ) 一种抗氧化肽组合物及其制备方法和应用, 2021, 第 4 作者, 专利号: CN112587439A( 8 ) 一种含有胜肽的水溶性溶液及应用, 2020, 第 4 作者, 专利号: CN111714405A( 9 ) 一种寡肽醇凝胶或水醇凝胶及其制备方法和应用, 2020, 第 4 作者, 专利号: CN111481463A( 10 ) 基于氨基酸的含纳米银的抗菌水凝胶及其制备方法和用途, 2018, 第 4 作者, 专利号: CN107625725A
出版信息
发表论文
(1) High-entropy non-covalent cyclic peptide glass, Nature Nanotechnology, 2024, 第 1 作者(2) Self-assembled amphiphilic peptide hydrogels for antimicrobial application, Current Opinion in Colloid & Interface Science, 2024, 第 4 作者 通讯作者(3) Effective Treatment of Helicobacter pylori Infection Using Supramolecular Antimicrobial Peptide Hydrogels, Biomacromolecules, 2024, 第 5 作者 通讯作者(4) Multistep Desolvation as a Fundamental Principle Governing Peptide Self-Assembly Through Liquid���Liquid Phase Separation, CCS Chemistry, 2024, 第 1 作者 通讯作者(5) Water-modulated low-wavelength fluorescence emission of PSmOrange, COLLOIDS AND SURFACES A: PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2024, 第 3 作者 通讯作者(6) Metal Ion-Coordinated Biomolecular Noncovalent Glass with Ceramic-like Mechanics, CCS Chemistry, 2024, 第 4 作者 通讯作者(7) Peptide Self-assembly: From Ordered to Disordered, Accounts of Chemical Research, 2024, 第 2 作者(8) 微观作用力对肽自组装过程中结构演化的影响:分子模拟研究, Effect of microscopic interactions on the evolution of structures in peptide self-assembly process:a molecular dynamics study, 中国科学:化学, 2023, 第 2 作者(9) Treatment of Superbug Infection through a Membrane-Disruption and Immune-Regulation Cascade Effect Based on Supramolecular Peptide Hydrogels, Advanced Functional Materials, 2023, 第 4 作者 通讯作者(10) Molecular Engineering of Ordered Piezoelectric Sulfonic Acid-Containing Assemblies, SMALL, 2023, 第 5 作者(11) Peptide self-assembly through liquid-liquid phase separation, Chem, 2023, 第 1 作者(12) Steering phase-separated droplets to control fibrillar network evolution of supramolecular peptide hydrogels, MATTER, 2023, 第 5 作者 通讯作者(13) Biomolecular glass with amino acid and peptide nanoarchitectonics, SCIENCE ADVANCES, 2023, 第 2 作者(14) Enzyme-driven oxygen-fuelled pathway selectivity of tyrosine-containing peptide oxidation evolution, CHEMICAL ENGINEERING JOURNAL, 2022, 第 3 作者(15) Metal-Free Nanoassemblies of Water-Soluble Photosensitizer and Adenosine Triphosphate for Efficient and Precise Photodynamic Cancer Therapy, ACS NANO, 2021, 第 4 作者(16) Supramolecular Nanofibrils Formed by Coassembly of Clinically Approved Drugs for Tumor Photothermal Immunotherapy, ADVANCED MATERIALS, 2021, 第 4 作者(17) Porphyrin/Ionic-Liquid Co-assembly Polymorphism Controlled by Liquid-Liquid Phase Separation, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 第 1 作者(18) Injectable self-assembled bola-dipeptide hydrogels for sustained photodynamic prodrug delivery and enhanced tumor therapy, JOURNAL OF CONTROLLED RELEASE, 2020, 第 4 作者(19) TunableMechanical and Optoelectronic Properties ofOrganic Cocrystals by Unexpected Stacking Transformation from H- toJ- and X-Aggregation, ACS NANO, 2020, 第 8 作者(20) Acid-Activatable Transmorphic Peptide-Based Nanomaterials for Photodynamic Therapy, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 第 4 作者(21) Deciphering the structure-property relationship in coumarin-based supramolecular organogel materials, COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2020, 第 2 作者(22) Coassembly-Induced Transformation of Dipeptide Amyloid-Like Structures into Stimuli-Responsive Supramolecular Materials, ACS NANO, 2020, 第 2 作者(23) Multifunctional Antimicrobial Biometallohydrogels Based on Amino Acid Coordinated Self-Assembly, SMALL, 2020, 第 2 作者(24) A versatile cyclic dipeptide hydrogelator: self-assembly and rheology in various physiological conditions, COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2019, 第 4 作者(25) Metal-Ion Modulated Structural Transformation of Amyloid-Like Dipeptide Supramolecular Self-Assembly, ACS NANO, 2019, 第 2 作者(26) Nucleation and Growth of Amino Acid and Peptide Supramolecular Polymers through Liquid-Liquid Phase Separation, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 第 1 作者(27) Stoichiometry-controlled secondary structure transition of amyloid-derived supramolecular dipeptide co-assemblies, COMMUNICATIONS CHEMISTRY, 2019, 第 2 作者(28) The dominant role of oxygen in modulating the chemical evolution pathways of tyrosine in peptides: dityrosine or melanin, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 第 3 作者(29) Self-assembling endogenous biliverdin as a versatile near-infrared photothermal nanoagent for cancer theranostics, ADVANCED MATERIALS, 2019, 第 3 作者(30) Cyclic dipeptide nanoribbons formed by dye-mediated hydrophobic self-assembly for cancer chemotherapy, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2019, 第 2 作者(31) Hierarchically oriented organization in supramolecular peptide crystals, NATURE REVIEWS CHEMISTRY, 2019, 第 1 作者(32) Unravelling the Weak Interactions in Binary Clusters of Serotonin and Amino Acid Residues, CHEMISTRYSELECT, 2019, 第 6 作者(33) Ultrafast Deep-Ultraviolet Laser Ionization Mass Spectrometry Applicable To Identify Phenylenediamine Isomers, ANALYTICAL CHEMISTRY, 2018, 第 2 作者(34) Charge-Induced Secondary Structure Transformation of Amyloid-Derived Dipeptide Assemblies from beta-Sheet to alpha-Helix, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 第 2 作者(35) Charge-Induced Secondary Structure Transformation of Amyloid-Derived Dipeptide Assemblies from b-Sheet to a-Helix, Angew. Chem. Int. Ed., 2018, (36) Amino acid coordination driven self-assembly for enhancing both the biological stability and tumor accumulation of curcumin, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 第 3 作者(37) Amino Acid Coordination-Driven Self-Assembly for Enhancing both Biological Stability and Tumor Accumulation of Curcumin, Angew. Chem. Int. Ed., 2018, (38) Crystalline Dipeptide Nanobelts Based on Solid-Solid Phase Transformation Self-Assembly and Their Polarization Imaging of Cells, ACS APPLIED MATERIALS & INTERFACES, 2018, 第 5 作者 通讯作者(39) Quantum Tunneling Tautomer of N , N -Dimethyl- p -toluidineDehydrogenates Identified by Deep-UV Laser Ionization Mass Spectroscopy, ACS OMEGA, 2018, 第 2 作者(40) Smart Peptide-Based Supramolecular Photodynamic Metallo-Nanodrugs Designed by Multicomponent Coordination Self-Assembly, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 第 4 作者(41) Tungsten-copper clusters assembled on porous alumina for optical limiting applications, JOURNAL OF MATERIALS CHEMISTRY C, 2017, 第 2 作者(42) Trace Water as Prominent Factor to Induce Peptide Self-Assembly: Dynamic Evolution and Governing Interactions in Ionic Liquids, SMALL, 2017, 第 2 作者(43) Multiscale simulations for understanding the evolution and mechanism of hierarchical peptide self-assembly, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 第 1 作者(44) Self-Assembled Zinc/Cystine-Based Chloroplast Mimics Capable of Photoenzymatic Reactions for Sustainable Fuel Synthesis, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 第 2 作者(45) 配位辅助氨基酸自组装的结构演变过程及其机制研究, 中国化学会第十六届胶体与界面化学会议论文摘要集——第五分会:生命科学与医学中的胶体化学, 2017, 第 1 作者(46) Charge-transfer interactions between TCNQ and silver clusters Ag-20 and Ag-13, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2016, 第 4 作者(47) A theoretical study of weak interactions in phenylenediamine homodimer clusters, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2016, 第 1 作者(48) Unraveling weak interactions in aniline-pyrrole dimer clusters, SCIENCE CHINA-CHEMISTRY, 2016, 第 1 作者(49) All-solid-state deep ultraviolet laser for single-photon ionization mass spectrometry, REVIEW OF SCIENTIFIC INSTRUMENTS, 2016, 第 1 作者(50) Vibrational spectroscopic identification of isoprene, pinenes and their mixture, CHINESE CHEMICAL LETTERS, 2016, 第 2 作者(51) Facile preparation of N- and O-doped hollow carbon spheres derived from poly(o-phenylenediamine) for supercapacitors, JOURNAL OF MATERIALS CHEMISTRY A, 2015, 第 1 作者(52) Quantum-size-effect accommodation of gold clusters with altered fluorescence of dyes, RSC ADVANCES, 2015, 第 5 作者(53) 丙烯酸-丙烯酰胺共聚物吸水树脂的制备, Synthesis and Water Absorbency of Poly (Acrylic Acid-co-Acrylamide), 胶体与聚合物, 2013, 第 4 作者(54) 丙烯酸类共聚物超吸水树脂的合成研究, Study on Synthesis of Acrylics Copolymer Water Superabsorbent Resin, 化学推进剂与高分子材料, 2012, 第 5 作者(55) 淀粉接枝类高吸水树脂的合成研究, Synthesis of Starch Graft Water Superabsorbent Resin, 化学推进剂与高分子材料, 2012, 第 4 作者(56) 片状纳米聚对苯二胺的制备与表征, Synthesis and characterization of nanosheet-like poly(p-phenylenediamine), 功能材料, 2012, 第 2 作者(57) 电子传输材料联苯喹喔啉的合成与性质研究, Synthesis and Properties of Diphenylquinoxaline as Electron-transporting Materials, 材料导报, 2011, 第 5 作者(58) 微乳液法制备聚苯胺及其表征, Synthesis and Characterization of Polyaniline via Microemulsion, 胶体与聚合物, 2011, 第 4 作者
科研活动
科研项目
( 1 ) 液-液相分离调控代谢物自组装的机制及用于先天性代谢缺陷治疗的研究, 负责人, 中国科学院计划, 2024-01--2027-01( 2 ) 活性肽配位多级组装体的可控构筑及其肿瘤诊疗应用, 负责人, 国家任务, 2024-01--2027-12( 3 ) 生物分子玻璃的物理化学基础与生物应用, 负责人, 研究所自主部署, 2023-01--2025-12( 4 ) 液-液相分离调控寡肽自组装的机制及其用于神经退行性疾病治疗的研究, 负责人, 国家任务, 2022-01--2025-12( 5 ) 寡肽自组装的物理化学机制研究, 负责人, 中国科学院计划, 2022-01--2025-12( 6 ) 肽自组装的结构演变过程与机制研究, 负责人, 地方任务, 2020-01--2023-12( 7 ) 氨基酸配位自组装水凝胶的结构调控及抗菌性能研究, 负责人, 国家任务, 2019-01--2021-12( 8 ) 介尺度调控短肽分子自组装动态过程的机制研究, 负责人, 国家任务, 2017-05--2018-11
参与会议
(1)Self-coacervates of Amino Acid as Minimalistic Biomimetic Protocell 2023-05-18(2)液-液相分离介导的寡肽自组装成核-生长机制 中国化学会第十八届全国胶体与界面化学学术会议 2023-04-10(3)液-液相分离介导的超分子聚合物成核-生长 中国化学会第十七届全国胶体与界面化学学术会议 2019-07-29