基本信息
晁彦杰  男  博导  中国科学院上海巴斯德研究所
电子邮件: yjchao@ips.ac.cn
通信地址: 岳阳路320号新生命科学大楼B座711室
邮政编码: 200031

研究领域

肠道细菌,微生物致病机理,非编码RNA,基因表达调控

招生信息

   
招生专业
071005-微生物学
071009-细胞生物学
100103-病原生物学
招生方向
细菌致病机理
非编码RNA
基因表达调控

教育背景

2008-12--2014-09   Max-Planck Institute & Humboldt University of Berlin, Germany   PhD

工作经历

   
工作简历
2016-08~2020-08,Howard Hughes Medical Institute & Tufts University, USA, Postdoc
2014-09~2016-08,University of Wuerzburg, Germany, Postdoc
社会兼职
2018-05-01-今,BMC Genomics, Associate Editor

教授课程

高级微生物学

专利与奖励

   
专利成果
( 1 ) 检测牛结核抗体的免疫胶体金试纸条及制备方法, 发明专利, 2009, 第 5 作者, 专利号: CN100494352

( 2 ) 一种适用于牛结核抗体检测的试剂盒及应用, 发明专利, 2007, 第 3 作者, 专利号: CN1982439

出版信息

   
发表论文
[1] Dong, Xingxing, Chao, Yanjie, Zhou, Yang, Zhou, Rui, Zhang, Wei, Fischetti, Vincent A, Wang, Xiaohong, Feng, Ye, Li, Jinquan. The global emergence of a novel Streptococcus suis clade associated with human infections. EMBO MOLECULAR MEDICINE[J]. 2021, 13(7): http://dx.doi.org/10.15252/emmm.202013810.
[2] Wang, Chuan, Chao, Yanjie, Matera, Gianluca, Gao, Qian, Vogel, Joerg. The conserved 3 ' UTR-derived small RNA NarS mediates mRNA crossregulation during nitrate respiration. NUCLEIC ACIDS RESEARCH[J]. 2020, 48(4): 2126-2143, https://www.webofscience.com/wos/woscc/full-record/WOS:000525957000040.
[3] Chao, Yanjie, Li, Lei, Girodat, Dylan, Foerstner, Konrad U, Said, Nelly, Corcoran, Colin, Smiga, Michal, Papenfort, Kai, Reinhardt, Richard, Wieden, HansJoachim, Luisi, Ben F, Vogel, Joerg. In Vivo Cleavage Map Illuminates the Central Role of RNase E in Coding and Non-coding RNA Pathways. MOLECULAR CELL[J]. 2017, 65(1): 39-51, http://dx.doi.org/10.1016/j.molcel.2016.11.002.
[4] Chao, Yanjie, Vogel, Joerg. A 3 ' UTR-Derived Small RNA Provides the Regulatory Noncoding Arm of the Inner Membrane Stress Response. MOLECULAR CELL[J]. 2016, 61(3): 352-363, http://dx.doi.org/10.1016/j.molcel.2015.12.023.
[5] Saadeh, Bashir, Caswell, Clayton C, Chao, Yanjie, Berta, Philippe, Wattam, Alice Rebecca, Roop, R Martin, II, OCallaghana, David. Transcriptome-Wide Identification of Hfq-Associated RNAs in Brucella suis by Deep Sequencing. JOURNAL OF BACTERIOLOGY[J]. 2016, 198(3): 427-435, https://www.webofscience.com/wos/woscc/full-record/WOS:000369163300009.
[6] Miyakoshi, Masatoshi, Chao, Yanjie, Vogel, Joerg. Cross talk between ABC transporter mRNAs via a target mRNA-derived sponge of the GcvB small RNA. EMBO JOURNALnull. 2015, 34(11): 1478-1492, https://www.webofscience.com/wos/woscc/full-record/WOS:000355996900007.
[7] Miyakoshi, Masatoshi, Chao, Yanjie, Vogel, Joerg. Regulatory small RNAs from the 3 ' regions of bacterial mRNAs. CURRENT OPINION IN MICROBIOLOGYnull. 2015, 24: 132-139, http://dx.doi.org/10.1016/j.mib.2015.01.013.
[8] Caldelari, Isabelle, Chao, Yanjie, Romby, Pascale, Vogel, Joerg. RNA-Mediated Regulation in Pathogenic Bacteria. COLD SPRING HARBOR PERSPECTIVES IN MEDICINE[J]. 2013, 3(9): https://www.webofscience.com/wos/woscc/full-record/WOS:000325093800003.
[9] Chao, Yanjie, Papenfort, Kai, Reinhardt, Richard, Sharma, Cynthia M, Vogel, Joerg. An atlas of Hfq-bound transcripts reveals 3 ' UTRs as a genomic reservoir of regulatory small RNAs. EMBO JOURNAL[J]. 2012, 31(20): 4005-4019, https://www.webofscience.com/wos/woscc/full-record/WOS:000310055400008.
[10] Kroeger, Carsten, Dillon, Shane C, Cameron, Andrew D S, Papenfort, Kai, Sivasankaran, Sathesh K, Hokamp, Karsten, Chao, Yanjie, Sittka, Alexandra, Hebrard, Magali, Haendler, Kristian, Colgan, Aoife, Leekitcharoenphon, Pimlapas, Langridge, Gemma C, Lohan, Amanda J, Loftus, Brendan, Lucchini, Sacha, Ussery, David W, Dorman, Charles J, Thomson, Nicholas R, Vogel, Joerg, Hinton, Jay C D. The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2012, 109(20): E1277-E1286, https://www.webofscience.com/wos/woscc/full-record/WOS:000304369800013.
[11] Deltcheva, Elitza, Chylinski, Krzysztof, Sharma, Cynthia M, Gonzales, Karine, Chao, Yanjie, Pirzada, Zaid A, Eckert, Maria R, Vogel, Joerg, Charpentier, Emmanuelle. CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. NATURE[J]. 2011, 471(7340): 602-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000288951200035.
[12] Chao, Yanjie, Vogel, Joerg. The role of Hfq in bacterial pathogens. CURRENT OPINION IN MICROBIOLOGYnull. 2010, 13(1): 24-33, http://dx.doi.org/10.1016/j.mib.2010.01.001.
[13] Chen, Yingyu, Chao, Yanjie, Deng, Quantao, Liu, Tao, Xiang, Jie, Chen, Jun, Zhou, Jinhai, Zhan, Zhihua, Kuang, Youji, Cai, Hong, Chen, Huanchun, Guo, Aizhen. Potential challenges to the Stop TB Plan for humans in China; cattle maintain M-bovis and M-tuberculosis. TUBERCULOSIS[J]. 2009, 89(1): 95-100, http://dx.doi.org/10.1016/j.tube.2008.07.003.
[14] 韩晖, 肖勇, 任易, 晁彦杰, 郭爱珍, 叶临湘. 分枝杆菌散在分布重复单位分型法在分辨北京株结核分枝杆菌基因分型中型中的初步研究. 中华流行病学杂志[J]. 2008, 29(10): 1050-1051, [15] Sun, Zhaogang, Chao, Yanjie, Zhang, Xuxia, Zhang, Jianyuan, Li, Yan, Qiu, Yunqing, Liu, Yi, Nie, Lihui, Guo, Aizhen, Li, Chuanyou. Characterization of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates in China. JOURNAL OF CLINICAL MICROBIOLOGY[J]. 2008, 46(12): 4075-4077, https://www.webofscience.com/wos/woscc/full-record/WOS:000261247900038.
[16] B.F. Yan, Y.J. Chao, Z. Chen, K.G. Tian, C.B. Wang, X.M. Lin, H.C. Chen, A.Z. Guo. Serological survey of bovine herpesvirus type 1 infection in China. Veterinary Microbiology. 2008, 127(1): 136-141, http://dx.doi.org/10.1016/j.vetmic.2007.08.025.
[17] 陈颖钰, 邓铨涛, 郭爱珍, 晁彦杰. 基于结核菌素与CFP10/ESAT6的牛IFN-γ检测法在牛结核病诊断中的比较研究. 中国奶牛. 2008, 12-14, http://lib.cqvip.com/Qikan/Article/Detail?id=27482581.
[18] 韩晖, 肖勇, 任易, 晁彦杰, 郭爱珍, 叶临湘. 分枝杆菌散在分布重复单位分型法在分辨北京株结核分枝杆菌基因分型中的初步研究. 中华流行病学杂志. 2008, 29(10): 1050-1051, http://lib.cqvip.com/Qikan/Article/Detail?id=28385533.
[19] 陈颖钰, 邓铨涛, 詹枝华, 郭爱珍, 项杰, 陈军, 周金海, 曾庆志, 杜义祥, 魏武, 童庆伟, 晁彦杰, 匡有吉, 陈焕春. 人IFN-γ体外释放检测法的建立及其在结核病诊断中的应用. 生物工程学报[J]. 2008, 24(9): 1653-1657, http://lib.cqvip.com/Qikan/Article/Detail?id=28334646.
[20] 钦博, 万学济, 胡巧云, 喻正军, 晁彦杰, 郭爱珍, 陈焕春, 谭亚娣. 牛型分枝杆菌MPB70蛋白胶乳凝集方法的建立及应用. 中国预防兽医学报[J]. 2007, 29(1): 58-62, http://lib.cqvip.com/Qikan/Article/Detail?id=23770772.
[21] 颜邦芬, 陈锃, 张书环, 林祥梅, 陈颖钰, 晁彦杰, 李德学, 宋念华, 陈焕春, 郭爱珍. 牛传染性鼻气管炎病毒gG蛋白的表达及gG-ELISA的建立. 生物工程学报[J]. 2007, 23(5): 806-811, http://lib.cqvip.com/Qikan/Article/Detail?id=25568675.
[22] 李川, 谭亚娣, 陈颖钰, 胡巧云, 马艳, 张桂荣, 钦博, 晁彦杰, 陈焕春, 郭爱珍. 牛IFN-γ原核表达、单克隆抗体制备及其ELISA检测方法的建立. 生物工程学报[J]. 2007, 23(1): 40-45, http://lib.cqvip.com/Qikan/Article/Detail?id=23819211.
[23] 张书环, 杨俊兴, 晁彦杰, 颜邦芬, 吴波, 曹莎, 陈颖钰, 谭亚娣, 陈焕春, 郭爱珍. 牛结核病抗体胶体金快速检测技术的建立和初步运用. 中国奶牛. 2007, http://lib.cqvip.com/Qikan/Article/Detail?id=1000089544.
[24] Han, Hui, Wang, Fang, Xiao, Yong, Ren, Yi, Chao, Yanjie, Guo, Aizhen, Ye, Lingxiang. Utility of mycobacterial interspersed repetitive unit typing for differentiating Mycobacterium tuberculosis isolates in Wuhan, China. JOURNAL OF MEDICAL MICROBIOLOGY[J]. 2007, 56(9): 1219-1223, https://www.webofscience.com/wos/woscc/full-record/WOS:000249703000014.
[25] 张书环, 吴波, 曹莎, 陈颖钰, 晁彦杰, 陈焕春, 郭爱珍. 牛分枝杆菌抗原MPB70、MPB83、CFP-10和ESAT-6的融合表达及相关特性分析. 中国人兽共患病学报[J]. 2007, 23(12): 861-865, http://lib.cqvip.com/Qikan/Article/Detail?id=25381586.
[26] 张桂荣, 万学济, 陈颖钰, 吴波, 晁彦杰, 吕文, 钦博, 郭爱珍, 陈焕春, 谭亚娣. 间接ELISA检测牛分枝杆菌抗体方法的建立及初步应用. 中国预防兽医学报[J]. 2007, 29(7): 555-560,568, http://lib.cqvip.com/Qikan/Article/Detail?id=25017874.
[27] 张书环, 杨俊兴, 晁彦杰, 颜邦芬, 吴波, 曹莎, 陈颖钰, 谭亚娣, 陈焕春, 郭爱珍. 牛结核病抗体胶体金快速检测技术的建立和应用. 动物医学进展[J]. 2007, 28(7): 17-24, http://lib.cqvip.com/Qikan/Article/Detail?id=24994167.

科研活动

   
科研项目
( 1 ) 病原细菌小RNA调控功能的系统研究, 主持, 国家级, 2022-07--2025-06
( 2 ) 原核非编码RNA研究, 主持, 国家级, 2022-05--2025-04

指导学生

现指导学生

王皓宇  硕士研究生  071009-细胞生物学  

林星宇  硕士研究生  100103-病原生物学  

金思卉  硕士研究生  086000-生物与医药