陈琛-中国科学院大学-UCAS

Research Areas

Plant molecular biology, Transcription regulation，Epigenetics, Abiotic response of plants

Education

2012.01 to 2017.03, The University of Western Ontario, Canada. Doctor of Philosophy in Biology

2008.09 to 2011.12, Sun Yat-Sen University, China. Graduate Study

2002.09 to 2006.07, Yangzte University, China. Bachelor of Bioengineering

Experience

Work Experience

2020.05 to Now, South China Botanical Garden, Chinese Academy of Science. The Regulation of

Plant Adaptivity (Principal Investigator)

2017.04 to 2020.03, London Research and Developmental Centre, Agriculture and Agri-Food

Canada. Postdoc

Publications

[1] Shu, Jie, Ding, Ning, Liu, Jun, Cui, Yuhai, Chen, Chen. Transcription elongator SPT6L regulates the occupancies of the SWI2/SNF2 chromatin remodelers SYD/BRM and nucleosomes at transcription start sites in Arabidopsis. NUCLEIC ACIDS RESEARCH[J]. 2022, 50(22): 12754-12767, http://dx.doi.org/10.1093/nar/gkac1126.
[2] Han, Danlu, Chen, Chen, Xia, Simin, Liu, Jun, Shu, Jie, Nguyen, Vi, Lai, Jianbin, Cui, Yuhai, Yang, Chengwei. Chromatin-associated SUMOylation controls the transcriptional switch between plant development and heat stress responses. PLANT COMMUNICATIONS[J]. 2021, 2(1): 85-95, http://dx.doi.org/10.1016/j.xplc.2020.100091.
[3] Shu, Jie, Chen, Chen, Li, Chenlong, Thapa, Raj K, Song, Jingpu, Xie, Xin, Nguyen, Vi, Bian, Shaomin, Liu, Jun, Kohalmi, Susanne E, Cui, Yuhai. Genome-wide occupancy of Arabidopsis SWI/SNF chromatin remodeler SPLAYED provides insights into its interplay with its close homolog BRAHMA and Polycomb proteins. PLANT JOURNAL[J]. 2021, 106(1): 200-213, https://www.webofscience.com/wos/woscc/full-record/WOS:000629696000001.
[4] Song, Jingpu, Xie, Xin, Chen, Chen, Shu, Jie, Thapa, Raj K, Vi Nguyen, Bian, Shaomin, Kohalmi, Susanne E, Marsolais, Frederic, Zou, Jitao, Cui, Yuhai. LEAFY COTYLEDON1 expression in the endosperm enables embryo maturation in Arabidopsis. NATURE COMMUNICATIONS[J]. 2021, 12(1): https://doaj.org/article/13b68548dfb648608295fce354e3ee15.
[5] Jie Shu, Chen Chen, Susanne E Kohalmi, Yuhai Cui. Evidence that AGL17 is a significant downstream target of CLF in floral transition control. PLANT SIGNALING & BEHAVIOR[J]. 2020, 15(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000534897800001.
[6] Hung, FuYu, Chen, Chen, Yen, MingRen, Hsieh, JoWei Allison, Li, Chenlong, Shih, YuanHsin, Chen, FangFang, Chen, PaoYang, Cui, Yuhai, Wu, Keqiang. The expression of long non-coding RNAs is associated with H3Ac and H3K4me2 changes regulated by the HDA6-LDL1/2 histone modification complex in Arabidopsis. NAR GENOMICS AND BIOINFORMATICS[J]. 2020, 2(3): http://dx.doi.org/10.1093/nargab/lqaa066.
[7] Shu, Jie, Chen, Chen, Li, Chenlong, Cui, Yuhai. The complexity of PRC2 catalysts CLF and SWN in plants. BIOCHEMICAL SOCIETY TRANSACTIONSnull. 2020, 48(6): 2779-2789, http://dx.doi.org/10.1042/BST20200660.
[8] Yu, Yaoguang, Liang, Zhenwei, Song, Xin, Fu, Wei, Xu, Jianqu, Lei, Yawen, Yuan, Liangbing, Ruan, Jiuxiao, Chen, Chen, Fu, Wenqun, Cui, Yuhai, Huang, Shangzhi, Li, Chenlong. BRAHMA-interacting proteins BRIP1 and BRIP2 are core subunits of Arabidopsis SWI/SNF complexes. NATURE PLANTS[J]. 2020, 6(8): 996-+, http://dx.doi.org/10.1038/s41477-020-0734-z.
[9] Shu, Jie, Chen, Chen, Thapa, Raj Kumar, Bian, Shaomin, Vi Nguyen, Yu, Kangfu, Yuan, ZeChun, Liu, Jun, Kohalmi, Susanne E, Li, Chenlong, Cui, Yuhai. Genome-wide occupancy of histone H3K27 methyltransferases CURLY LEAF and SWINGER in Arabidopsis seedlings. PLANT DIRECT[J]. 2019, 3(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000509897600007.
[10] Chen, Chen, Shu, Jie, Li, Chenlong, Thapa, Raj K, Vi Nguyen, Yu, Kangfu, Yuan, ZeChun, Kohalmi, Susanne E, Liu, Jun, Marsolais, Frederic, Huang, Shangzhi, Cui, Yuhai. RNA polymerase II-independent recruitment of SPT6L at transcription start sites in Arabidopsis. NUCLEIC ACIDS RESEARCH[J]. 2019, 47(13): 6714-6725, https://www.webofscience.com/wos/woscc/full-record/WOS:000490556600018.
[11] Li, Chenlong, Chen, Chen, Chen, Huhui, Wang, Suikang, Chen, Xuemei, Cui, Yuhai. Verification of DNA motifs in Arabidopsis using CRISPR/Cas9-mediated mutagenesis. PLANT BIOTECHNOLOGY JOURNAL[J]. 2018, 16(8): 1446-1451, https://www.webofscience.com/wos/woscc/full-record/WOS:000438359500006.
[12] Chen, Chen, Li, Chenlong, Wang, Ying, Renaud, Justin, Tian, Gang, Kambhampati, Shrikaar, Saatian, Behnaz, Vi Nguyen, Hannoufa, Abdelali, Marsolais, Frederic, Yuan, ZeChun, Yu, Kangfu, Austin, Ryan S, Liu, Jun, Kohalmi, Susanne E, Wu, Keqiang, Huang, Shangzhi, Cui, Yuhai. Cytosolic acetyl-CoA promotes histone acetylation predominantly at H3K27 in Arabidopsis. NATURE PLANTS[J]. 2017, 3(10): 814-824,

Research Interests

My group is mainly focused on the regulation of transcription machinery in response to different environmental signals in plants. We integrate multiple strategies such as molecular biology, genetics, epigenetics, high-throughput sequencing, and bioinformatics to reveal the molecular mechanisms of transition from transcription initiation to elongation and the real-time responses of transcription machinery to biotic and abiotic stresses. Take advantage of those fundamental discoveries, we expect to provide potential options for improving the adaptivity and sustainability of crops in adverse environmental conditions.

Students

现指导学生

张志博士研究生 071010-生物化学与分子生物学

丁宁博士研究生 071007-遗传学

陈文艺硕士研究生 071010-生物化学与分子生物学

刘玉娟博士研究生 071010-生物化学与分子生物学

刘锦源硕士研究生 086000-生物与医药

王瀛婕硕士研究生 071007-遗传学