基本信息
段学锋 男 硕导 中国科学院微生物研究所
电子邮件: duanxf@im.ac.cn
通信地址: 北京市朝阳区北辰西路1号院3号A418
邮政编码:
电子邮件: duanxf@im.ac.cn
通信地址: 北京市朝阳区北辰西路1号院3号A418
邮政编码:
教育背景
2002-04--2006-03 日本九州大学医学研究院 医学博士1995-09--2000-06 北京大学医学部 医学学士
工作经历
工作简历
2013-10~现在, 中国科学院微生物研究所, 副研究员2011-01~2013-09,日本九州大学免疫机制研究中心, 助理教授2009-04~2010-12,日本九州大学生体防御医学研究所, 特任助教2006-04~2009-03,日本九州大学医学研究院, 博士后2002-04~2006-03,日本九州大学医学研究院, 医学博士1995-09~2000-06,北京大学医学部, 医学学士
教授课程
基础免疫学
专利与奖励
专利成果
( 1 ) 一种检测嗜肺军团菌毒力的方法, 2020, 第 3 作者, 专利号: 201810317033.7( 2 ) 一种可检测热原的单克隆细胞系的制备方法, 2018, 第 5 作者, 专利号: 201810317034.1
出版信息
发表论文
(1) UBL7 enhances antiviral innate immunity by promoting Lys27-linked polyubiquitination of MAVS, CELL REPORTS, 2023, 第 8 作者(2) Legionella pneumophila Risk from Cooling Tower Systems in China, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2022, 第 14 作者(3) SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2(ZYG)(11)(B) activity, JOURNAL OF CELL BIOLOGY, 2022, 第 12 作者(4) Declined miR-181a-5p expression is associated with impaired natural killer cell development and function with aging, AGING CELL, 2021, 第 5 作者(5) Influenza virus matrix protein M1 interacts with SLD5 to block host cell cycle, CELLULAR MICROBIOLOGY, 2019, 第 7 作者(6) The virulence of legionella pneumophila is positively correlated with its ability to stimulate nf-b activation, FUTURE MICROBIOLOGY, 2018, 第 11 作者(7) Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology, AGING AND DISEASE, 2018, 第 2 作者(8) Natural killer cells are activated and play a protective role against ZIKA virus infection in mice, SCIENCE BULLETIN, 2017, 第 1 作者(9) The AP-1 transcription factor JunB is required for Th17 cell differentiation, SCIENTIFIC REPORTS, 2017, 第 7 作者(10) Bidirectional factors impact the migration of nk cells to draining lymph node in aged mice during influenza virus infection, EXPERIMENTAL GERONTOLOGY, 2017, 第 1 作者(11) Differential immune response of influenza a virus-infected dendritic cells and association with autophagy, FUTURE VIROLOGY, 2017, 第 11 作者(12) Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus, NATURE COMMUNICATIONS, 2015, 第 5 作者(13) NK-cells are involved in thymic atrophy induced by influenza A virus infection, JOURNAL OF GENERAL VIROLOGY, 2015, 第 1 作者(14) DOCK5 functions as a key signaling adaptor that links Fc��RI signals to microtubule dynamics during mast cell degranulation, THE JOURNAL OF EXPERIMENTAL MEDICINE, 2014, 第 4 作者(15) The Rac activator DOCK2 regulates natural killer cell-mediated cytotoxicity in mice through the lytic synapse formation, BLOOD, 2013, 第 5 作者(16) Antiangiogenic Tumor Therapy by DNA Vaccine Inducing Aquaporin-1-Specific CTL Based on Ubiquitin-Proteasome System in Mice, JOURNAL OF IMMUNOLOGY, 2012, 第 5 作者(17) DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses, BLOOD, 2012, 第 0 作者(18) Blockade of Inflammatory Responses by a Small-Molecule Inhibitor of the Rac Activator DOCK2, CHEMISTRY & BIOLOGY, 2012, 第 3 作者(19) Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells, JOURNAL OF IMMUNOLOGY, 2008, 第 7 作者
科研活动
科研项目
( 1 ) 潜在高致病性流感病毒跨种感染和传播风险评估体系的建立和应用, 负责人, 国家任务, 2023-11--2026-10( 2 ) 微生物及代谢产物调控“微生物-代谢-免疫”轴的机制, 负责人, 国家任务, 2021-12--2026-11( 3 ) 大气细颗粒物对流感病毒环境适应性、致病性及机体免疫防御的影响机制, 参与, 国家任务, 2021-01--2024-12( 4 ) 中亚地区重要细菌传播风险和控制的分子机理研, 负责人, 国家任务, 2018-01--2020-12