He Cui, Ph.D,  CAS Center for Excellence Brain Science and Intelligence Technology(Institute of Neuroscience)
Address: No. 320 Yueyang Road, Shanghai District, China
Postal Code: 200031

Research Areas

The ultimate function of the brain is to produce behavior. How primates generate appropriate motor commands driving sophisticated skeletomuscular system in response to signals from the complex and dynamic environment is a central challenge in neuroscience. By combining behavioral, neurophysiological, and computational approaches, our lab has sought to decipher the neural codes underlying predictive sensorimotor control. Ongoing research has provided direct neurophysiological evidence in parietal cortex in support for the longstanding forward model.

Because sensorimotor behavior arises from concerted population activity in a collection of interconnected brain areas, sensorimotor signals embodied in the parietal cortex must also rely on other cortical and subcortical regions. In future experiments, we plan not only to extend neural recording to the motor cortex and cerebellum, but also will chronically record large-scale neuronal populations in those areas via implanted micro-electrode arrays and/or two-photon optical imaging, to elucidate fundamental mechanisms underlying sensorimotor coding and learning. Moreover, we will further dissociate sensory vs motor variables by introducing virtual-reality and even examine the causal roles of each of these areas with experimental interventions, such as reversible inactivation and optogenetics.

To elucidate the neural basis of motor control at the mechanistic level also will help neuroprosthetics and brain-inspired robotics. In future experiments, we will not only decode population neuronal activity recorded from monkeys to control robotic arms in real-time, but also will collaborate with clinicians to implement brain-machine interface in patients with brain disorders affecting motor control. In collaboration with experts in artificial intelligence and machine learning, we will also apply contemporary neural principles of sensorimotor control to the development of next generation of intelligent robots.


1997-08--2003-08   University of Illinois at Urbana-Champaign  ph.D.   
1994-08--1997-07  Chinese Academy of Sciences  M.S.   
1989-08--1994-07   Tsinghua University  B.S.   


Work Experience

2008-12~2016-01,Medical College of Georgia,Assistant Professor, Associate Professor 

2003-08~2008-12,California Institute of Technology, Postdoc



1)         Li Y.,Wang Y. and Cui H.* (2018) Eye-hand coordination during flexible manual interception of an abruptly appearing, moving target, Journal of Neurophysiology, 119,221-234.

2)         Cui H.* (2016) Forward prediction in the posterior parietal cortex and dynamic brain-machine interface.  Frontier in Integrative Neuroscience, 10-35.

3)         Cui H.* (2014) From intention to action: hierarchical sensorimotor transformation in the posterior parietal cortex, eNeuro 1, e0017-14.2014.

4)         Li Y. and Cui H.* (2013) Dorsal parietal area 5 encodes immediate reach in sequential arm movements, Journal of Neuroscience 33,14455-14465.

5)         Ma R., Cui H., Lee S., Anastasio T.J., and Malpeli J.G.* (2013) Predictive encoding of moving target trajectory by neurons in the parabigeminal nucleus. Journal of Neurophysiology109, 2029-2043.

6)         Torres E.B.*, Quian Quiroga R., Cui H., and Buneo C.A. (2013) Neural correlates of learning and trajectory planning in the posterior parietal cortex. Frontiers in Integrative Neuroscience 7, 39.

7)         Cui H.* and Andersen R.A. (2011) Different representations of potential and selected motor plans by distinct parietal areas, Journal of Neuroscience 31, 18130-18136.

8)         Andersen R.A.* and Cui H. (2009) Intention, action planning, and decision making in parietal-frontal circuits, Neuron 63, 568-583.

9)         Baldauf D.*, Cui H., and Andersen R.A. (2008) The Posterior Parietal Cortex Encodes in Parallel Both Goals for Double-Reach Sequences. Journal of Neuroscience 28, 10081-10089.

10)     Cui H.* and Andersen R.A. (2007) Posterior parietal cortex encodes autonomously selected motor plans, Neuron 56, 552-559.

11)     Quian Quiroga R.*, Snyder L.H., Batista A.P., Cui H., and Andersen, R.A. (2006) Movement intention is better predicted than attention in the posterior parietal cortex, Journal of Neuroscience 26, 3615-3620.

12)     Gruberg E.*, Dudkin E., Wang Y., Marín G., Salas C., Sentis E., Letelier J., Mpodozis J., Malpeli J.G., Cui H., Ma R., Northmore D., and Udin S. (2006) Influencing and interpreting visual input: the role of a visual feedback system, Journal of Neuroscience 26, 10368-10371.

13)     Cui H. and Malpeli J.G.* (2003) Activity in the parabigeminal nucleus during eye movements directed at moving and stationary targets, Journal of Neurophysiology89, 3128-3142.

14)     Wang Y.J., Cui H., and Qi X.L. (1996) Initializing receptive field-like weights in BP learning network: (I) Effect on convergence rate, Progress in Natural Science 6, 189-194.

15)     Cui H., Qi X.L., and Wang Y.J. (1996) Initializing receptive field-like weights in BP learning network (II) Internal representation, Progress in Natural Science 6, 308-315.

16)     Qi X.L., Cui H., and Wang Y.J. (1996) Initializing receptive field-like weights in BP learning network (III) Theoretical analysis, Progress in Natural Science 6, 451-457

Research Interests

(1) The role of posterior parietal cortex of macaque in predictive motor control, 2017-01~2020-12

(2) Neural regulation mechanism and cognitive function assessment of mental disorders, 2016-12~2019-11

(3) Brain-computer Interface、Motor and Cognitive rehabilitation, 2017-06~2017-12

(4) Research on neural information analysis and interaction technology for bionic prosthetic hand perception and control, 2018-05~2017-12


Institute of Automation

Shenzhen Institute of Advanced Technology, CAS

Shanghai Jiao Tong Universtiy

Zhejiang University

Shanghai Mental Health Center

Zhongshan Hospital

National Research Center for Rehabilitation Aids

Institute of Semiconductors

National Center of Nanoscience and Technology



Tianwei Wang         Doctoral Student      Neuroscience 

Yiheng Zhang          Doctoral Student     Neuroscience

Chenyang Li             Mater Student         Neuroscience

Yun Chen                 Mater Student         Neuroscience

Ruichen Zheng        Mater Student         Neuroscience

Yongcheng Guo      Mater Student         Neuroscience

Ang Zhu                   Mater Student        Neuroscience