基本信息
刘玲  女  博导  中国科学院微生物研究所
电子邮件: liul@im.ac.cn
通信地址: 北辰西路1号院3号F608
邮政编码:

研究领域

真菌天然药物发现与生物合成

招生信息

   
招生专业
100705-微生物与生化药学
招生方向
天然产物化学
天然产物生物合成

教育背景

2005-09--2009-06   中国科学院微生物研究所   博士
2002-09--2005-06   中国科学院成都生物研究所   硕士

工作经历

   
工作简历
2018-03~现在, 中国科学院微生物研究所, 项目研究员
2016-11~2018-12,加州大学洛杉矶分校, 访问学者
2011-07~2018-03,中国科学院微生物研究所, 副研究员
2009-07~2011-06,中国科学院微生物研究所, 助理研究员
社会兼职
2019-04-19-今,中国天然药物青年编委,
2019-01-01-2024-12-31,中国海洋药物博士论坛青年委员会委员,
2018-07-01-今,菌物化学专业委员会委员,
2018-01-01-今,菌物学报编委,

专利与奖励

   
奖励信息
(1) 首批“中国科学院卓越青年科学家”, 部委级, 2014
(2) 中国科学院优秀博士学位论文提名奖, 部委级, 2010
专利成果
[1] 刘玲, 郭良栋, 郭龙芳. 一种抗幽门螺旋杆菌活性的聚酮化合物及其制备方法和应用. CN: CN110982700A, 2020-04-10.

[2] 刘玲, 刘高然, 郭龙芳. 抗幽门螺旋杆菌活性的化合物及其制备方法和应用. CN: CN110951620A, 2020-04-03.

[3] 刘玲, 郭良栋, 郭龙芳, 贾佳. 抗幽门螺旋杆菌活性的蒽醌类化合物及其应用. CN: CN110951619A, 2020-04-03.

[4] 车永胜, 曹亚, 刘玲, 陈晓燕, 郭良栋. 一种抗肿瘤活性的新化合物及其制备方法和应用. 中国: CN103130757A, 2013-06-05.

[5] 刘玲, 丁永良, 李伯刚, 张国林. 一种从胡芦巴种子中分离4-羟基异亮氨酸的方法. 中国: CN1955160, 2007-05-02.

出版信息

   
发表论文
[1] Tian, Sufei, Bing, Jian, Chu, Yunzhuo, Chen, Jingjing, Cheng, Shitong, Wang, Qihui, Zhang, Jingping, Ma, Xiaochun, Zhou, Baosen, Liu, Ling, Huang, Guanghua, Shang, Hong. Genomic epidemiology of Candida auris in a general hospital in Shenyang, China: a three-year surveillance study. EMERGING MICROBES & INFECTIONS[J]. 2021, 10(1): 1088-1096, http://dx.doi.org/10.1080/22221751.2021.1934557.
[2] Bolin Hou, Sushi Liu, Ruiyun Huo, Yueqian Li, Jinwei Ren, Wenzhao Wang, Tao Wei, Xuejun Jiang, Wenbing Yin, Hongwei Liu, Ling Liu, Erwei Li. New Diterpenoids and Isocoumarin Derivatives from the Mangrove-Derived Fungus Hypoxylon sp.. Marine Drugs[J]. 2021, 19(362): https://doaj.org/article/021f3f8f752543ac8006e8e7014130ff.
[3] 程璐, 翟亚楠, 孙立彦, 刘玲. 地衣及其内生真菌活性次级代谢产物研究进展. 菌物学报[J]. 2021, 40(1): 14-30, http://lib.cqvip.com/Qikan/Article/Detail?id=7104321563.
[4] Ren, Jinwei, Huo, Ruiyun, Liu, Gaoran, Liu, Ling. New Andrastin-Type Meroterpenoids from the Marine-Derived Fungus Penicillium sp.. MARINE DRUGS[J]. 2021, 19(4): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000643220100001.
[5] Guo zhe, Huo, Ruiyun, Niu, Shubin, liu xingzhong, Liu, Ling. Alternariasin A, new pentacyclic cytochalasin from the fungus Alternaria alternate.. J Antibiot.[J]. 2021, 74: 596-, [6] Liu, Gaoran, Huo, Ruiyun, Zhai, Yanan, Liu, Ling. New Bioactive Sesquiterpeniods From the Plant Endophytic Fungus Pestalotiopsis theae. FRONTIERS IN MICROBIOLOGY[J]. 2021, 12: https://www.webofscience.com/wos/woscc/full-record/WOS:000639829800001.
[7] Liu, Gaoran, Niu, Shubin, Liu, Ling. Alterchromanone A, one new chromanone derivative from the mangrove endophytic fungusAlternaria longipes. JOURNAL OF ANTIBIOTICS[J]. 2021, 74(2): 152-155, https://www.webofscience.com/wos/woscc/full-record/WOS:000562652200001.
[8] Guo, Longfang, Lin, Jie, Niu, Shubin, Liu, Shuchun, Liu, Ling. Pestalotiones A-D: Four New Secondary Metabolites from the Plant Endophytic Fungus Pestalotiopsis Theae. MOLECULES[J]. 2020, 25(3): https://www.webofscience.com/wos/woscc/full-record/WOS:000515384800040.
[9] Guo LongFang, Liu GaoRan, Liu Ling. Caryophyllene-type sesquiterpenoids and alpha-furanones from the plant endophytic fungus Pestalotiopsis theae. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2020, 18(4): 261-267, https://www.webofscience.com/wos/woscc/full-record/WOS:000532266300005.
[10] Zhao, Chen, Liu, Gaoran, Liu, Xingzhong, Zhang, Lan, Li, Lin, Liu, Ling. Pycnidiophorones A-D, four new cytochalasans from the wetland derived fungus Pycnidiophora dispersa. RSC ADVANCES[J]. 2020, 10(66): 40384-40390, https://www.webofscience.com/wos/woscc/full-record/WOS:000587926200044.
[11] Guo, Longfang, Niu, Shubin, Chen, Shuanglin, Liu, Ling. Diaporone A, a new antibacterial secondary metabolite from the plant endophytic fungus Diaporthe sp.. JOURNAL OF ANTIBIOTICS[J]. 2020, 73(2): 116-119, https://www.webofscience.com/wos/woscc/full-record/WOS:000507497100007.
[12] Lv, JianMing, Gao, YaoHui, Zhao, Huan, Awakawa, Takayoshi, Liu, Ling, Chen, GuoDong, Yao, XinSheng, Hu, Dan, Abe, Ikuro, Gao, Hao. Biosynthesis of Biscognienyne B Involving a Cytochrome P450-Dependent Alkynylation. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2020, 59(32): 13531-13536, https://www.webofscience.com/wos/woscc/full-record/WOS:000535042600001.
[13] Longfang Guo, Jie Lin, Shubin Niu, Shuchun Liu, Ling Liu. Pestalotiones A–D: Four New Secondary Metabolites from the Plant Endophytic Fungus Pestalotiopsis Theae. Molecules[J]. 2020, 25(3): https://doaj.org/article/514c3408d5a84d6981bf6fbfdf6921aa.
[14] Guo, Longfang, Zhang, Caining, Gao, Quan, Hou, Bolin, Liu, Ling, Yang, Huaiyi, Jiang, Xuejun. Chloropupukeananin and Pestalofone C Regulate Autophagy through AMPK and Glycolytic Pathway. CHEMISTRY & BIODIVERSITY[J]. 2020, 17(3): https://www.webofscience.com/wos/woscc/full-record/WOS:000511481500001.
[15] Zhang, Jinyu, Li, Yumei, Ren, Fengxia, Zhang, Yang, Liu, Xingzhong, Liu, Ling, Che, Yongsheng. Phomanolides C-F from a Phoma sp.: Meroterpenoids Generated via Hetero-Diels-Alder Reactions. JOURNAL OF NATURAL PRODUCTS[J]. 2019, 82(6): 1678-1685, https://www.webofscience.com/wos/woscc/full-record/WOS:000473827300033.
[16] Qu, XinYing, Ren, JinWei, Peng, AiHong, Lin, ShiQi, Lu, DanDan, Du, QianQian, Liu, Ling, Li, Xia, Li, ErWei, Xie, WeiDong. Cytotoxic, Anti-Migration, and Anti-Invasion Activities on Breast Cancer Cells of Angucycline Glycosides Isolated from a Marine-Derived Streptomyces sp.. MARINE DRUGS[J]. 2019, 17(5): [17] Liu, Ling, Tang, ManCheng, Tang, Yi. Fungal Highly Reducing Polyketide Synthases Biosynthesize Salicylaldehydes That Are Precursors to Epoxycyclohexenol Natural Products. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2019, 141(50): 19538-19541, https://www.webofscience.com/wos/woscc/full-record/WOS:000503917800004.
[18] Hou, Bolin, Xu, Shanshan, Xu, Yang, Gao, Quan, Zhang, Caining, Liu, Ling, Yang, Huaiyi, Jiang, Xuejun, Che, Yongsheng. Grb2 binds to PTEN and regulates its nuclear translocation to maintain the genomic stability in DNA damage response. CELL DEATH & DISEASE[J]. 2019, 10(8): http://dx.doi.org/10.1038/s41419-019-1762-3.
[19] Pan, Yuanyuan, Liu, Ling, Guan, Feifei, Li, Erwei, Jin, Jin, Li, Jinyang, Che, Yongsheng, Liu, Gang. Characterization of a Prenyltransferase for Iso-A82775C Biosynthesis and Generation of New Congeners of Chloropestolides. ACS CHEMICAL BIOLOGY[J]. 2018, 13(3): 703-711, https://www.webofscience.com/wos/woscc/full-record/WOS:000428003000028.
[20] Yan, Siyuan, Liu, Ling, Ren, Fengxia, Gao, Quan, Xu, Shanshan, Hou, Bolin, Wang, Yange, Jiang, Xuejun, Che, Yongsheng. Sunitinib induces genomic instability of renal carcinoma cells through affecting the interaction of LC3-II and PARP-1. CELL DEATH & DISEASE[J]. 2017, 8(8): e2988-, https://www.webofscience.com/wos/woscc/full-record/WOS:000409550500025.
[21] Lin, Jie, Wang, Renlei, Xu, Guohua, Ding, Zhengfeng, Zhu, Xueshen, Li, Erwei, Liu, Ling. Two new polyketides from the ascomycete fungus Leptosphaeria sp. JOURNAL OF ANTIBIOTICS[J]. 2017, 70(6): 743-746, https://www.webofscience.com/wos/woscc/full-record/WOS:000402447800005.
[22] Han, Junjie, Liu, Congcong, Li, Li, Zhou, Hui, Liu, Li, Bao, Li, Chen, Qian, Song, Fuhang, Zhang, Lixin, Li, Erwei, Liu, Ling, Pei, Yunfei, Jin, Cheng, Xue, Yanfen, Yin, Wenbing, Ma, Yanhe, Liu, Hongwei. Decalin-Containing Tetramic Acids and 4-Hydroxy-2-pyridones with Antimicrobial and Cytotoxic Activity from the Fungus Coniochaeta cephalothecoides Collected in Tibetan Plateau (Medog). JOURNAL OF ORGANIC CHEMISTRY[J]. 2017, 82(21): 11474-11486, https://www.webofscience.com/wos/woscc/full-record/WOS:000414724000016.
[23] Zheng, Yanjing, Ma, Ke, Lyu, Haining, Huang, Ying, Liu, Hongwei, Liu, Ling, Che, Yongsheng, Liu, Xingzhong, Zou, Huixi, Yin, WenBing. Genetic Manipulation of the COP9 Signalosome Subunit PfCsnE Leads to the Discovery of Pestaloficins in Pestalotiopsis fici. ORGANIC LETTERS[J]. 2017, 19(17): 4700-4703, https://www.webofscience.com/wos/woscc/full-record/WOS:000409566400073.
[24] Lin, Jie, Niu, Shubin, Ding, Zhengfeng, Wang, Renlei, Dai, Qun, Wei, Wei, Luo, Rongrong, Liu, Ling. Isolation and Characterization of Aphidicolin Derivatives from Tolypocladium inflatum. MOLECULES[J]. 2017, 22(7): https://doaj.org/article/da75ddfef3f44cf797fdd16c7d3f383b.
[25] Yan, Siyuan, Wei, Xiaoli, Xu, Shanshan, Sun, Hui, Wang, Weijun, Liu, Ling, Jiang, Xuejun, Zhang, Yongxiang, Che, Yongsheng. 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 spatially mediates autophagy through the AMPK signaling pathway. ONCOTARGET[J]. 2017, 8(46): 80909-80922, https://www.webofscience.com/wos/woscc/full-record/WOS:000412465700070.
[26] Lee, Seungjun, Kim, DongCheol, Park, JinSoo, Son, JaeYoung, Sohn, Jae Hak, Liu, Ling, Che, Yongsheng, Oh, Hyuncheol. Penicillospirone from a marine isolate of Penicillium sp (SF-5292) with anti-inflammatory activity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2017, 27(15): 3516-3520, http://dx.doi.org/10.1016/j.bmcl.2017.05.066.
[27] Lin, Jie, Wang, Renlei, Xu, Guohua, Ding, Zhengfeng, Zhu, Xueshen, Liu, Xingzhong, Zou, Jian, Chen, Guodong, Li, Li, Liu, Ling. New cadinane sesquiterpenoids from the basidiomycetous fungus Pholiota sp.. RSC ADVANCES[J]. 2016, 6(113): 112527-112533, https://www.webofscience.com/wos/woscc/full-record/WOS:000389708700102.
[28] Liu, Ling, Han, Yu, Xiao, Junhai, Li, Li, Guo, Liangdong, Jiang, Xuejun, Kong, Lingyi, Che, Yongsheng. Chlorotheolides A and B, Spiroketals Generated via Diels-Alder Reactions in the Endophytic Fungus Pestalotiopsis theae. JOURNAL OF NATURAL PRODUCTS[J]. 2016, 79(10): 2616-2623, https://www.webofscience.com/wos/woscc/full-record/WOS:000386745300024.
[29] Zhang, Yang, Zhang, Zhuowei, Wang, Bo, Liu, Ling, Che, Yongsheng. Design and synthesis of natural product derivatives with selective and improved cytotoxicity based on a sesquiterpene scaffold. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2016, 26(8): 1885-1888, http://dx.doi.org/10.1016/j.bmcl.2016.03.022.
[30] Wang, Bo, Zhang, Zhuowei, Guo, Liangdong, Liu, Ling. New Cytotoxic Meroterpenoids from the Plant Endophytic Fungus Pestalotiopsis fici. HELVETICA CHIMICA ACTA[J]. 2016, 99(2): 151-156, https://www.webofscience.com/wos/woscc/full-record/WOS:000370326000010.
[31] Wang, Xiuna, Zhang, Xiaoling, Liu, Ling, Xiang, Meichun, Wang, Wenzhao, Sun, Xiang, Che, Yongsheng, Guo, Liangdong, Liu, Gang, Guo, Liyun, Wang, Chengshu, Yin, WenBing, Stadler, Marc, Zhang, Xinyu, Liu, Xingzhong. Genomic and transcriptomic analysis of the endophytic fungus Pestalotiopsis fici reveals its lifestyle and high potential for synthesis of natural products. BMC GENOMICS[J]. 2015, 16(1): http://dx.doi.org/10.1186/s12864-014-1190-9.
[32] Guo, Zhe, Ren, Fengxia, Che, Yongsheng, Liu, Gang, Liu, Ling. New Bergamotane Sesquiterpenoids from the Plant Endophytic Fungus Paraconiothyrium brasiliense. MOLECULES[J]. 2015, 20(8): 14611-14620, https://doaj.org/article/b0b6d637c1d4410a8b14b85f9fe50873.
[33] Liu, Ling, Chen, Xiaoyan, Li, Dong, Zhang, Yang, Li, Li, Guo, Liangdong, Cao, Ya, Che, Yongsheng. Bisabolane Sesquiterpenoids from the Plant Endophytic Fungus Paraconiothyrium brasiliense. JOURNAL OF NATURAL PRODUCTS[J]. 2015, 78(4): 746-753, [34] Zhang, Jinyu, Liu, Ling, Wang, Bo, Zhang, Yang, Wang, Lili, Lie, Xingzhong, Che, Yongsheng. Phomanolides A and B from the Fungus Phoma sp.: Meroterpenoids Derived from a Putative Tropolonic Sesquiterpene via Hetero-Diels-Alder Reactions. JOURNAL OF NATURAL PRODUCTS[J]. 2015, 78(12): 3058-3066, https://www.webofscience.com/wos/woscc/full-record/WOS:000367562600024.
[35] Wang, Xiuna, Wu, Fan, Liu, Ling, Liu, Xingzhong, Che, Yongsheng, Keller, Nancy P, Guo, Liyun, Yin, WenBing. The bZIP transcription factor PfZipA regulates secondary metabolism and oxidative stress response in the plant endophytic fungus Pestalotiopsis fici. FUNGAL GENETICS AND BIOLOGY[J]. 2015, 81: 221-228, http://dx.doi.org/10.1016/j.fgb.2015.03.010.
[36] Liu, Ling, Zhao, Chen, Li, Li, Guo, Liangdong, Che, Yongsheng. Pestalotriols A and B, new spiro2.5octane derivatives from the endophytic fungus Pestalotiopsis fici. RSC ADVANCES[J]. 2015, 5(96): 78708-78711, https://www.webofscience.com/wos/woscc/full-record/WOS:000361675800039.
[37] Xu, Xinxin, Liu, Ling, Zhang, Fan, Wang, Wenzhao, Li, Jinyang, Guo, Liangdong, Che, Yongsheng, Liu, Gang. Identification of the First Diphenyl Ether Gene Cluster for Pestheic Acid Biosynthesis in Plant Endophyte Pestalotiopsis fici. CHEMBIOCHEM[J]. 2014, 15(2): 284-292, https://www.webofscience.com/wos/woscc/full-record/WOS:000329877400014.
[38] Liu, Ling, Li, Yan, Li, Li, Cao, Ya, Guo, Liangdong, Liu, Gang, Che, Yongsheng. Spiroketals of Pestalotiopsis fici Provide Evidence for a Biosynthetic Hypothesis Involving Diversified Diels-Alder Reaction Cascades. JOURNAL OF ORGANIC CHEMISTRY[J]. 2013, 78(7): 2992-3000, https://www.webofscience.com/wos/woscc/full-record/WOS:000317327800017.
[39] Liu, Shuchun, Liu, Xiangyu, Guo, Liangdong, Che, Yongsheng, Liu, Ling. 2H-Pyran-2-one and 2H-Furan-2-one Derivatives from the Plant Endophytic Fungus Pestalotiopsis fici. CHEMISTRY & BIODIVERSITY[J]. 2013, 10(11): 2007-2013, https://www.webofscience.com/wos/woscc/full-record/WOS:000328321900006.
[40] Liu, Shuchun, Guo, Liangdong, Che, Yongsheng, Liu, Ling. Pestaloficiols Q-S from the plant endophytic fungus Pestalotiopsis fici. FITOTERAPIA[J]. 2013, 85: 114-118, https://www.webofscience.com/wos/woscc/full-record/WOS:000317172000017.
[41] Ling Liu. α-Pyrone and α-furanone derivatives from the plant endophytic fungus Pestalotiopsis fici. Chem. Biodivers. 2013, [42] Liu Ling, Tan Xiao Bin, Xu Peng, Wen Hong, Li, W, Zhao, Q. Research on a Multipath Routing for Multihop Cellular Network. PROCEEDINGS OF THE 31ST CHINESE CONTROL CONFERENCEnull. 2012, 5493-5498, [43] Liu, Ling, Bruhn, Torsten, Guo, Liangdong, Goetz, Daniel C G, Brun, Reto, Stich, August, Che, Yongsheng, Bringmann, Gerhard. Chloropupukeanolides C-E: Cytotoxic Pupukeanane Chlorides with a Spiroketal Skeleton from Pestalotiopsis fici. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2011, 17(9): 2604-2613, http://124.16.144.217/handle/311023/1672.
[44] Liu Shuchun, Ye Xin, Guo Liangdong, Liu Ling. 源于植物内生无花果拟盘多毛孢真菌的新环氧环己二醇衍生物. 中国天然药物[J]. 2011, 9(5): 374-379, http://lib.cqvip.com/Qikan/Article/Detail?id=39149223.
[45] 刘述春, 叶昕, 郭良栋, 刘玲. 源于植物内生无花果拟盘多毛孢真菌的新环氧环己二醇衍生物. 中国天然药物. 2011, 9(5): 374-379, http://lib.cqvip.com/Qikan/Article/Detail?id=39149223.
[46] Ling Liu. Cytotoxic isoprenylated epoxycyclohexanediols from the plant endophyte Pestalotiopsis fici. Chin. J. Nat. Med. 2011, [47] Liu Ling. Bioactive metabolites from the plant endophyte Pestalotiopsis fici. Mycology[J]. 2011, [48] Liu, Ling, Gao, Hao, Chen, Xulin, Cai, Xiaoyue, Yang, Leilei, Guo, Liangdong, Yao, Xinsheng, Che, Yongsheng. Brasilamides A-D: Sesquiterpenoids from the Plant Endophytic Fungus Paraconiothyrium brasiliense. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2010, 2010(17): 3302-3306, http://124.16.144.217/handle/311023/1832.
[49] Liu, Ling, Niu, Shubin, Lu, Xinhua, Chen, Xulin, Zhang, Hua, Guo, Liangdong, Che, Yongsheng. Unique metabolites of Pestalotiopsis fici suggest a biosynthetic hypothesis involving a Diels-Alder reaction and then mechanistic diversification. CHEMICAL COMMUNICATIONS[J]. 2010, 46(3): 460-462, http://www.corc.org.cn/handle/1471x/2375676.
[50] 刘述春, 刘玲. 源于植物内生无花果拟盘多毛孢真菌的新色原酮类次生代谢产物研究. 菌物学报[J]. 2010, 582-587, http://lib.cqvip.com/Qikan/Article/Detail?id=34623340.
[51] Ling Liu. Isoprenylated chromones from the plant endophytic fungus Pestalotiopsis fici. Mycosystema. 2010, [52] Liu, Ling, Li, Yan, Liu, Shuchun, Zheng, Zhihui, Chen, Xulin, Zhang, Hua, Guo, Liangdong, Che, Yongsheng. Chloropestolide A, an Antitumor Metabolite with an Unprecedented Spiroketal Skeleton from Pestalotiopsis fici. ORGANIC LETTERS[J]. 2009, 11(13): 2836-2839, http://www.corc.org.cn/handle/1471x/2375574.
[53] Liu, Ling, Liu, Shuchun, Niu, Shubin, Guo, Liangdong, Chen, Xulin, Che, Yongsheng. Isoprenylated Chromone Derivatives from the Plant Endophytic Fungus Pestalotiopsis fici. JOURNAL OF NATURAL PRODUCTS[J]. 2009, 72(8): 1482-1486, http://124.16.144.217/handle/311023/1554.
[54] Liu, Ling, Liu, Shuchun, Chen, Xulin, Guo, Liangdong, Che, Yongsheng. Pestalofones A-E, bioactive cyclohexanone derivatives from the plant endophytic fungus Pestalotiopsis fici. BIOORGANIC & MEDICINAL CHEMISTRY[J]. 2009, 17(2): 606-613, http://dx.doi.org/10.1016/j.bmc.2008.11.066.
[55] Liu, Ling, Liu, Shuchun, Jiang, Lihua, Chen, Xulin, Guo, Liangdong, Che, Yongsheng. Chloropupukeananin, the first chlorinated pupukeanane derivative, and its precursors from Pestalotiopsis fici. ORGANIC LETTERS[J]. 2008, 10(7): 1397-1400, http://www.corc.org.cn/handle/1471x/2375444.
[56] Liu, Ling, Tian, Renrong, Liu, Shuchun, Chen, Xulin, Guo, Liangdong, Che, Yongsheng. Pestaloficiols A-E, bioactive cyclopropane derivatives from the plant endophytic fungus Pestalotiopsis fici. BIOORGANIC & MEDICINAL CHEMISTRY[J]. 2008, 16(11): 6021-6026, http://dx.doi.org/10.1016/j.bmc.2008.04.052.

科研活动

   
科研项目
( 1 ) 中国科学院卓越青年科学家项目, 主持, 部委级, 2014-06--2017-06
( 2 ) 无花果拟盘多毛孢菌独特化合物的深入研究, 主持, 国家级, 2014-01--2017-12
( 3 ) 珍稀、药用生物替代品规模化关键技术研究与产品开发, 主持, 国家级, 2012-01--2015-12
( 4 ) 植物内生真菌次生代谢产物结构与功能研究, 主持, 部委级, 2011-06--2015-06
( 5 ) 基于化学表观遗传方法的植物内生真菌中新结构、活性化合物的发现, 主持, 市地级, 2013-01--2015-12
( 6 ) 植物内生真菌来源独特化合物的结构、活性与生物合成途径, 主持, 国家级, 2011-01--2013-12
( 7 ) 无花果拟盘多毛孢菌中丙二烯化合物的生物合成途径研究, 主持, 国家级, 2018-01--2021-12
( 8 ) 海洋微生物天然产物的高效深度挖掘, 主持, 国家级, 2018-08--2021-12
( 9 ) 绿木霉菌中环氧环己烯聚酮化合物的生物合成途径研究, 主持, 国家级, 2020-01--2023-12
参与会议
(1)特境真菌活性次级代谢产物研究   CJNM第二届青年编委会会议暨青年学者论坛   2019-11-16
(2)环氧环己二醇化合物生物合成研究   第十四届海洋药物学术年会暨 2019 国际海洋药物论坛   2019-11-11
(3)无花果拟盘多毛孢菌活性次级代谢产物研究   第十二届中美华人化学教授会议   2016-06-23

指导学生

已指导学生

王燕鸽  硕士研究生  071010-生物化学与分子生物学  

现指导学生

刘高然  硕士研究生  085238-生物工程  

侯卜琳  博士研究生  071005-微生物学  

郭龙芳  博士研究生  071010-生物化学与分子生物学  

张若晗  硕士研究生  085238-生物工程