基本信息
熊彩侨 女 硕导 中国科学院化学研究所
电子邮件: xiongcq@iccas.ac.cn
通信地址: 海淀区中关村北一街2号
邮政编码: 100190
电子邮件: xiongcq@iccas.ac.cn
通信地址: 海淀区中关村北一街2号
邮政编码: 100190
招生信息
招生专业
070302-分析化学
招生方向
颗粒质谱分析
教育背景
2009-09--2012-06 中国科学院化学研究所 理学博士2006-09--2009-06 重庆大学 理学硕士2002-09--2006-06 重庆大学 理学学士
工作经历
工作简历
2015-03~现在, 中国科学院化学研究所, 副研究员2012-07~2015-03,中国科学院化学研究所, 助理研究员2009-09~2012-06,中国科学院化学研究所, 理学博士2006-09~2009-06,重庆大学, 理学硕士2002-09~2006-06,重庆大学, 理学学士
专利与奖励
奖励信息
(1) 颗粒质谱与成像, 一等奖, 其他, 2019
专利成果
( 1 ) 手持式离子源装置以及质谱仪, 2023, 第 4 作者, 专利号: CN115705993A( 2 ) 一种MALDI质谱基质喷涂仪及喷涂方法, 2022, 第 5 作者, 专利号: CN115382712A( 3 ) 电喷雾质谱装置和电喷雾方法, 2022, 第 4 作者, 专利号: CN114792620A( 4 ) 一种醛气体检测方法、检测试纸及制备方法, 2022, 第 6 作者, 专利号: CN114486867A( 5 ) 一种醛气体检测方法、检测试纸及制备方法, 2022, 第 6 作者, 专利号: CN114486867A( 6 ) 一种醛气体检测方法、检测试纸及制备方法, 2022, 第 6 作者, 专利号: CN114486867A( 7 ) 一种复杂样品实时在线分析系统及方法, 2022, 第 4 作者, 专利号: CN114460213A( 8 ) 一种复杂样品实时在线分析系统及方法, 2022, 第 4 作者, 专利号: CN114460213A( 9 ) 一种毛细管纸喷雾离子源装置及离子生成方法, 2022, 第 3 作者, 专利号: CN114078687A( 10 ) 一种MALDI质谱基质喷涂仪, 2021, 第 5 作者, 专利号: CN214811999U( 11 ) 石墨炔在作为MALDI基质检测小分子物质中的应用, 2020, 第 5 作者, 专利号: CN109752447B( 12 ) 检测纳米载药系统在生物体内的生物分布的方法, 2019, 第 5 作者, 专利号: CN110118816A( 13 ) 用于质谱反应加速和信号增强的涡流管及实现方法, 2019, 第 4 作者, 专利号: CN110112051A( 14 ) 颗粒淌度质谱仪及颗粒的分析方法, 2019, 第 2 作者, 专利号: CN110085505A( 15 ) 有机物分析的方法及糖异构体的相对定量方法, 2019, 第 4 作者, 专利号: CN109932415A( 16 ) 用于飞行时间质谱仪的金属镀层氧化铝陶瓷电极片, 2019, 第 5 作者, 专利号: CN109256323A( 17 ) 9‑羟基‑3‑异吩恶嗪酮在基质辅助激光解吸电离中的用途, 2018, 第 1 作者, 专利号: CN107543860A( 18 ) 多模式电离源及其应用, 2017, 第 6 作者, 专利号: CN107154337A( 19 ) N‑苯基萘胺类化合物作为MALDI基质的应用, 2017, 第 3 作者, 专利号: CN107085033A( 20 ) 检测颗粒质量的质谱装置、用途及测量方法, 2017, 第 5 作者, 专利号: CN106981412A( 21 ) 液相薄层色谱-质谱联用装置、用途及检测方法, 2017, 第 4 作者, 专利号: CN106932524A( 22 ) 一种便携式离子阱调频质谱仪的数字测控系统, 2017, 第 3 作者, 专利号: CN106653554A( 23 ) 一种用于离子分子真空在线反应与检测的质谱装置, 2014, 第 6 作者, 专利号: CN104198632A( 24 ) 一种具有低温电荷检测器的颗粒离子阱质谱仪, 2014, 第 3 作者, 专利号: CN103745905A( 25 ) 一种离子双向引入和传输的四极杆质量分析装置, 2014, 第 3 作者, 专利号: CN103681208A( 26 ) 一种平面离子阱质量分析器, 2014, 第 4 作者, 专利号: CN103606509A( 27 ) 蒽醌或蒽醌衍生物在作为基质辅助紫外-可见光激光解吸电离质谱中的基质的应用, 2014, 第 4 作者, 专利号: CN103604861A( 28 ) 一种灵敏的辉光放电直接离子化方法及其装置, 2013, 第 4 作者, 专利号: CN103094050A( 29 ) 一种制作质谱仪中质量分析器的方法, 2012, 第 3 作者, 专利号: CN102623275A( 30 ) 硝酸萘乙二胺及其制备方法与应用, 2012, 第 4 作者, 专利号: CN102531924A( 31 ) 一种大气压下进样离子源装置, 2012, 第 3 作者, 专利号: CN102339720A( 32 ) 一种质谱仪器及其专用离子传输加热装置, 2012, 第 3 作者, 专利号: CN102324373A( 33 ) 一种利用三角波信号控制质量分析装置的方法, 2012, 第 3 作者, 专利号: CN102324372A( 34 ) 一种双重离子阱质谱仪, 2011, 第 2 作者, 专利号: CN102290319A( 35 ) 一种基于热辅助辉光放电的质谱离子源装置及其离子化分析方法, 2011, 第 6 作者, 专利号: CN102263006A( 36 ) 一种圆柱形离子阱质谱仪, 2011, 第 2 作者, 专利号: CN102034668A
出版信息
发表论文
(1) Accurate and High-Resolution Particle Mass Measurement Using a Peak Filtering Algorithm, Analytical Chemistry, 2024, 第 1 作者(2) Revealing the In Situ Behavior of Aggregation-Induced Emission Nanoparticles and Their Biometabolic Effects via Mass Spectrometry Imaging, ACS NANO, 2023, 第 12 作者 通讯作者(3) Urine and serum metabolic profiling combined with machine learning for autoimmune disease discrimination and classification, CHEMICAL COMMUNICATIONS, 2023, 第 4 作者(4) Pocket-Size Wireless Nanoelectrospray Ionization Mass Spectrometry for Metabolic Analysis of Salty Biofluids and Single Cells, ANALYTICAL CHEMISTRY, 2023, 第 11 作者(5) Biofluids Metabolic Profiling Based on PS@Fe 3 O 4 -NH 2 Magnetic Beads-Assisted LDI-MS for Liver Cancer Screening, ANALYTICAL CHEMISTRY, 2022, 第 6 作者(6) Biofluids Metabolic Profiling Based on PS@Fe3O4-NH2 Magnetic Beads-Assisted LDI-MS for Liver Cancer Screening, ANALYTICAL CHEMISTRY, 2022, 第 6 作者(7) Profiling of Urine Carbonyl Metabolic Fingerprints in Bladder Cancer Based on Ambient Ionization Mass Spectrometry, ANALYTICAL CHEMISTRY, 2022, 第 8 作者 通讯作者(8) Laser Desorption/Ionization Mass Spectrometry Imaging: A New Tool to See through Nanoscale Particles in Biological Systems, CHEMISTRY-A EUROPEAN JOURNAL, 2022, 第 5 作者(9) High Speed Mass Measurement of a Single Metal-Organic Framework Nanocrystal in a Paul Trap, ANALYTICAL CHEMISTRY, 2022, 第 1 作者(10) Pocket-Size "MasSpec Pointer" for Ambient Ionization Mass Spectrometry, ANALYTICAL CHEMISTRY, 2021, 第 6 作者(11) Development of capillary-paper spray for small-molecule analysis in complex samples, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 第 3 作者 通讯作者(12) Development of capillary-paper spray for small-molecule analysis in complex samples (vol 413, pg 1099, 2021), ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 第 3 作者 通讯作者(13) MALDI-TOF/TOF tandem mass spectrometry imaging reveals non-uniform distribution of disaccharide isomers in plant tissues, FOOD CHEMISTRY, 2021, 第 5 作者 通讯作者(14) Response to Comment on "A Theoretical Method for Characterizing Nonlinear Effects in Paul Traps with Added Octopole Field", JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2021, 第 1 作者(15) Mass Spectrometry Imaging Reveals In Situ Behaviors of Multiple Components in Aerosol Particles, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 第 3 作者 通讯作者(16) Application of Graphdiyne in Surface-Assisted Laser Desorption Ionization Mass Spectrometry, ACS APPLIED MATERIALS & INTERFACES, 2021, 第 7 作者 通讯作者(17) Laser cleavable probes for in situ multiplexed glycan detection by single cell mass spectrometry (vol 10, pg 10958, 2019), CHEMICAL SCIENCE, 2020, 第 5 作者 通讯作者(18) Ultrafast Photocatalytic Reaction Screening by Mass Spectrometry, ANALYTICAL CHEMISTRY, 2020, 第 5 作者 通讯作者(19) Mass, Size, and Density Measurements of Microparticles in a Quadrupole Ion Trap, ANALYTICAL CHEMISTRY, 2019, 第 1 作者(20) Direct identification of forensic body fluids by MALDI-MS, ANALYST, 2019, 第 5 作者 通讯作者(21) 质谱成像在脑神经科学中的应用进展, Progress of Mass Spectrometry Imaging in Neuroscience, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2019, 第 4 作者(22) A Miniature Particle Mass Spectrometer, ANALYTICAL CHEMISTRY, 2019, 第 6 作者 通讯作者(23) Laser cleavable probes for in situ multiplexed glycan detection by single cell mass spectrometry, CHEMICAL SCIENCE, 2019, 第 5 作者 通讯作者(24) A novel mass spectrometry method based on competitive non-covalent interaction for the detection of biomarkers, CHEMICAL COMMUNICATIONS, 2018, 第 6 作者 通讯作者(25) Heat-Induced Rearrangement of the Disulfide Bond of Lactoglobulin Characterized by Multiply Charged MALDI-TOF/TOF Mass Spectrometry, ANALYTICAL CHEMISTRY, 2018, 第 4 作者(26) Utilizing a Mini-Humidifier To Deposit Matrix for MALDI Imaging, ANALYTICAL CHEMISTRY, 2018, 第 6 作者(27) Hot electron transfer promotes ion production in plasmonic metal nanostructure assisted laser desorption ionization mass spectrometry, CHEMICAL COMMUNICATIONS, 2018, 第 6 作者(28) Laser Cleavable Probes-Based Cell Surface Engineering for in Situ Sialoglycoconjugates Profiling by Laser Desorption/lonization Mass Spectrometry, ANALYTICAL CHEMISTRY, 2018, 第 4 作者(29) N-Phenyl-2-naphthylamine as a Novel MALDI Matrix for Analysis and in Situ Imaging of Small Molecules, ANALYTICAL CHEMISTRY, 2018, 第 4 作者(30) Mass spectrometry imaging of the in situ drug release from nanocarriers, SCIENCE ADVANCES, 2018, 第 4 作者 通讯作者(31) Differentiation and Relative Quantitation of Disaccharide Isomers by MALDI-TOF/TOF Mass Spectrometry, ANALYTICAL CHEMISTRY, 2018, 第 5 作者(32) Characterization of organic aerosol in Beijing by laser desorption ionization coupled with Fourier Transform Ion Cyclotron Resonance Mass spectrometry, ATMOSPHERIC ENVIRONMENT, 2017, 第 4 作者(33) Mass Spectrometry Imaging of Kidney Tissue Sections of Rat Subjected to Unilateral Ureteral Obstruction, SCIENTIFIC REPORTS, 2017, 第 6 作者(34) Nonlinear Ion Harmonics in the Paul Trap with Added Octopole Field: Theoretical Characterization and New Insight into Nonlinear Resonance Effect, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2016, 第 1 作者 通讯作者(35) Development of Visible-Wavelength MALDI Cell Mass Spectrometry for High-Efficiency Single-Cell Analysis, ANALYTICAL CHEMISTRY, 2016, 第 1 作者(36) Application of flowerlike MgO for highly sensitive determination of lead via matrix-assisted laser desorption/ionization mass spectrometry, RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2016, 第 5 作者(37) Electrospray soft-landing for the construction of non-covalent molecular nanostructures using charged droplets under ambient conditions, CHEMICAL COMMUNICATIONS, 2016, 第 4 作者(38) Rapidly Probing Antibacterial Activity of Graphene Oxide by Mass Spectrometry-based Metabolite Fingerprinting., SCIENTIFIC REPORTS, 2016, 第 4 作者(39) Fluorographene nanosheets: a new carbon-based matrix for the detection of small molecules by MALDI-TOF MS, RSC ADVANCES, 2016, 第 4 作者(40) 小分子物质的MALDI分析及质谱成像研究进展, Review of matrix-assisted laser desorption/ionization mass spectrometry in analysis and imaging of small molecules, 中国科学. 化学, 2016, 第 4 作者(41) The bridge between thin layer chromatography-mass spectrometry and high-performance liquid chromatography-mass spectrometry: The realization of liquid thin layer chromatography-mass spectrometry, JOURNAL OF CHROMATOGRAPHY A, 2016, 第 6 作者(42) Mass Measurement of Single Intact Nanoparticles in a Cylindrical Ion Trap, ANALYTICAL CHEMISTRY, 2016, 第 3 作者(43) In Situ Bioconjugation and Ambient Surface Modification Using Reactive Charged Droplets, ANALYTICAL CHEMISTRY, 2015, 第 4 作者(44) MALDI-TOF MS Imaging of Metabolites with a N-(1-Naphthyl) Ethylenediamine Dihydrochloride Matrix and Its Application to Colorectal Cancer Liver Metastasis, ANALYTICALCHEMISTRY, 2015, 第 4 作者(45) Mass spectrometry imaging reveals the sub-organ distribution of carbon nanomaterials, NATURE NANOTECHNOLOGY, 2015, 第 2 作者(46) A Theoretical Method for Characterizing Nonlinear Effects in Paul Traps with Added Octopole Field, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2015, 第 1 作者(47) Quantitative assessment of protein adsorption on microparticles with particle mass spectrometry, ANAL. CHEM., 2014, 第 1 作者(48) Nonlinear Effects in Paul Traps Operated in the Second Stability Region: Analytical Analysis and Numerical Verification, J. AM. SOC. MASS. SPECTROM., 2014, 第 1 作者(49) 1,5-diaminonaphthalene hydrochloride assisted laser desorption/ionization mass spectrometry imaging of small molecules in tissues following focal cerebral ischemia, ANAL. CHEM., 2014, 第 4 作者(50) Nonlinear effects in Paul traps operated in the second stability region: analytical analysis and numerical verification., JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2014, 第 1 作者(51) 1,5-Diaminonaphthalene Hydrochloride Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Small Molecules in Tissues Following Focal Cerebral Ischemia, ANALYTICAL CHEMISTRY, 2014, 第 5 作者(52) Quantitative Assessment of Protein Adsorption on Microparticles with Particle Mass Spectrometry, ANALYTICAL CHEMISTRY, 2014, 第 1 作者(53) Plasma-based ambient sampling/ionization/transmission integrated source for mass spectrometry, ANALYST, 2014, 第 4 作者(54) Ambient Aerodynamic Desorption/Ionization Method for Microparticle Mass Measurement, ANALYTICAL CHEMISTRY, 2013, 第 1 作者(55) Differentiation of Chinese liquors by using ambient glow discharge ionization mass spectrometry, ANALYST, 2013, 第 5 作者(56) Carbon Nanodots As a Matrix for the Analysis of Low-Molecular-Weight Molecules in Both Positive- and Negative-Ion Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and Quantification of Glucose and Uric Acid in Real Samples, ANALYTICAL CHEMISTRY, 2013, 第 7 作者(57) Study of Nonlinear Resonance Effect in Paul Trap, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2013, 第 2 作者(58) 诱导电喷雾:一种用于实际样品精确质量测定的内标新方法, J. AM. SOC. MASS SPECTROM., 2013, 第 5 作者(59) 泡利阱非线形共振效应的研究, J. AM. SOC. MASS SPECTROM., 2013, 第 2 作者(60) 空气动力解吸电离用于微球质量测定, ANAL. CHEM., 2013, 第 1 作者(61) Induced dual-nanospray: a novel internal calibration method for convenient and accurate mass measurement., JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2013, 第 7 作者(62) The development of charge detection-quadrupole ion trap mass spectrometry driven by rectangular and triangular waves, ANALYST, 2012, 第 1 作者(63) Characteristics of electrical field and ion motion in surface-electrode ion traps, JOURNAL OF MASS SPECTROMETRY, 2012, 第 3 作者(64) N-(1-Naphthyl) Ethylenediamine Dinitrate: A New Matrix for Negative Ion MALDI-TOF MS Analysis of Small Molecules, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2012, 第 3 作者(65) High-Salt-Tolerance Matrix for Facile Detection of Glucose in Rat Brain Microdialysates by MALDI Mass Spectrometry, ANALYTICAL CHEMISTRY, 2012, 第 3 作者(66) Structural characterization of synthetic polymers using Thermal-Assisted Atmospheric Pressure Glow Discharge Mass Spectrometry, ANALYST, 2012, 第 5 作者(67) Characterization of Column Packing Materials in High-Performance Liquid Chromatography by Charge-Detection Quadrupole Ion Trap Mass Spectrometry, ANALYTICALCHEMISTRY, 2011, 第 1 作者(68) Characterization of bioparticles using a miniature cylindrical ion trap mass spectrometer operated at rough vacuum, ANALYST, 2011, 第 2 作者(69) Potential Distribution and Transmission Characteristics in a Curved Quadrupole Ion Guide, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2011, 第 2 作者(70) Kinetic Parameters of Interaction Between Cell Membrane and Drug by ppKCE, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2011, 第 4 作者(71) Direct Analysis of Oligosaccharides and Alpha Hydroxy Acids in Fruits Using Electrosonic Spray Ionization Mass Spectrometry, ANALYST, 2011, 第 3 作者(72) 药物与细胞膜相互作用的ppKCE动力学参数, Kinetic Parameters of Interaction Between Cell Membrane and Drug by ppKCE, 高等学校化学学报, 2011, 第 4 作者(73) Characteristics of Stability Boundary and Frequency in Nonlinear Ion Trap Mass Spectrometer, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2010, 第 3 作者