基本信息
尹文兵  男  博导  中国科学院微生物研究所
电子邮件: yinwb@im.ac.cn
通信地址: 北京市朝阳区北辰西路1号院3号
邮政编码: 100101

招生信息

   
招生专业
071005-微生物学
招生方向
真菌天然产物发现,基因调控,合成生物学

教育背景

2006-06--2009-09 德国马尔堡大学 博士
2002-09--2005-07 首都师范大学 硕士
1998-09--2002-07 山西师范大学 学士

工作经历

   
工作简历
2014-01--今 中国科学院微生物研究所 研究员
2012-11--2014-01 美国加州大学洛杉矶分校 博士后
2009-10--2012-10 美国威斯康辛大学麦迪逊分校 研究助理

专利与奖励

   
奖励信息
(1) 国家优秀自费留学生奖学金,国家级,2008
专利成果
[1] 尹文兵, 李伟, 宋自力. 血红密孔菌WYS377及其在生产漆酶中的应用. CN: CN112852637A, 2021-05-28.

[2] 尹文兵, 李伟, 宋自力. 用于降解烟梗的复合酶及其在降解烟梗中的应用. CN: CN112852792A, 2021-05-28.

[3] 尹文兵, 刘欢. 多硫代二酮哌嗪合成相关蛋白质及其相关生物材料与应用. CN: CN112094330A, 2020-12-18.

[4] 尹文兵, 周爽, 张宏娇, 李自馨. 一个能在真菌中产生黄酮类化合物的NRPS-PKS杂合蛋白及其编码基因与应用. CN: CN111778222A, 2020-10-16.

[5] 尹文兵, 李伟, 马紫卉. 构巢曲霉异源表达系统的构建及其应用. CN: CN108795970A, 2018-11-13.

[6] 尹文兵, 范爱丽, 李伟, 王龙. Asperphenamate合成相关蛋白及其编码基因与应用. CN: CN107365368A, 2017-11-21.

[7] 尹文兵, 李伟, 吴凡, 吴广畏. 黑附球菌与曲霉属真菌共培养的方法及获得的化合物. CN: CN106676025A, 2017-05-17.

[8] 尹文兵, 李伟. 一种利用烟曲霉菌生产烟曲霉素的方法. CN: CN106591389A, 2017-04-26.

出版信息

   
发表论文
[1] Lyu, HaiNing, Zhang, Jinyu, Zhou, Shuang, Liu, HongWei, Zhuang, WenYing, Li, ShuMing, Yin, WenBing. Heterologous expression of a single fungal HR-PKS leads to the formation of diverse 2-alkenyl-tetrahydropyrans in model fungi. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2021, 19(38): 8377-8383, http://dx.doi.org/10.1039/d1ob01501j.
[2] 谢丽媛, 尹文兵, 李伟, 高伟. 白僵菌天然产物及其药理活性和生物合成研究进展. 天然产物研究与开发. 2021, 33(1): 150-164, http://lib.cqvip.com/Qikan/Article/Detail?id=7103834019.
[3] Zhang, Jinyu, Qi, Landa, Chen, Guocan, Yin, WenBing. Discovery and genetic identification of amphiphilic coprogen siderophores from Trichoderm hypoxylon. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2021, 105(7): 2831-2839, https://www.webofscience.com/wos/woscc/full-record/WOS:000631801100001.
[4] Xu, Xinran, Feng, Jin, Zhang, Peng, Fan, Jie, Yin, WenBing. A CRISPR/Cas9 Cleavage System for Capturing Fungal Secondary Metabolite Gene Clusters. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2021, 31(1): 8-15, https://www.webofscience.com/wos/woscc/full-record/WOS:000614595900003.
[5] Hou, Bolin, Liu, Sushi, Huo, Ruiyun, Li, Yueqian, Ren, Jinwei, Wang, Wenzhao, Wei, Tao, Jiang, Xuejun, Yin, Wenbing, Liu, Hongwei, Liu, Ling, Li, Erwei. New Diterpenoids and Isocoumarin Derivatives from the Mangrove-Derived Fungus Hypoxylon sp.. MARINE DRUGS[J]. 2021, 19(7): http://dx.doi.org/10.3390/md19070362.
[6] Liu, Huan, Fan, Jie, Zhang, Peng, Hu, Youcai, Liu, Xingzhong, Li, ShuMing, Yin, WenBing. New insights into the disulfide bond formation enzymes in epidithiodiketopiperazine alkaloids. CHEMICAL SCIENCE[J]. 2021, 12(11): 4132-4138, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179532/.
[7] Guo, Qingfeng, Chen, Jinhua, Ren, Yuwei, Yin, Zhenhua, Zhang, Juanjuan, Yang, Baocheng, Wang, Xuewei, Yin, Wenbing, Zhang, Wancun, Ding, Gang, Chen, Lin. Hydrazine-Containing Heterocycle Cytochalasan Derivatives From Hydrazinolysis of Extracts of a Desert Soil-Derived Fungus Chaetomium madrasense 375. FRONTIERS IN CHEMISTRY[J]. 2021, 9: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097171/.
[8] Zhiguo Liu, Wei Li, Peng Zhang, Jie Fan, Fangbo Zhang, Caixia Wang, Shuming Li, Yi Sun, Shilin Chen, Wenbing Yin. Tricarbocyclic core formation of tyrosine-decahydrofluorenes implies a three-enzyme cascade with XenF-mediated sigmatropic rearrangement as a prerequisite. Acta Pharmaceutica Sinica. B. 2021, 11(11): 3655-3664, [9] Liang, Min, Li, Wei, Qi, Landa, Chen, Guocan, Cai, Lei, Yin, WenBing. Establishment of a Genetic Transformation System in Guanophilic Fungus Amphichorda guana. JOURNAL OF FUNGI[J]. 2021, 7(2): https://www.webofscience.com/wos/woscc/full-record/WOS:000622629000001.
[10] Xu, Xinran, Huang, Runye, Yin, WenBing. An Optimized and Efficient CRISPR/Cas9 System for the Endophytic Fungus Pestalotiopsis fici. JOURNAL OF FUNGI[J]. 2021, 7(10): [11] Liang, Min, Lyu, HaiNing, Ma, ZiYing, Li, ErWei, Cai, Lei, Yin, WenBing. Genomics-driven discovery of a new cyclodepsipeptide from the guanophilic fungus Amphichorda guana. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2021, 19(9): 1960-1964, https://www.webofscience.com/wos/woscc/full-record/WOS:000627441700009.
[12] Lyu, HaiNing, Liu, HongWei, Keller, Nancy P, Yin, WenBing. Harnessing diverse transcriptional regulators for natural product discovery in fungi. NATURAL PRODUCT REPORTSnull. 2020, 37(1): 6-16, https://www.webofscience.com/wos/woscc/full-record/WOS:000509966800001.
[13] 宋自力, 廖头根, 张伟, 陈国参, 李伟, 汪世华, 尹文兵. 白腐真菌血红密孔菌漆酶复合酶预处理烟梗丝的响应面法优化. 菌物学报[J]. 2020, 39(5): 923-936, http://lib.cqvip.com/Qikan/Article/Detail?id=7102184766.
[14] 亓兰达, 魏鹏霖, 张晗星, 陈国参, 张英涛, 尹文兵. 后基因组时代害虫生防真菌次级代谢产物的研究进展. 中国科学:生命科学[J]. 2020, 50(6): 589-598, http://lib.cqvip.com/Qikan/Article/Detail?id=7102303924.
[15] Fan, Jie, Liao, Ge, LudwigRadtke, Lena, Yin, WenBing, Li, ShuMing. Formation of Terrestric Acid in Penicillium crustosum Requires Redox-Assisted Decarboxylation and Stereoisomerization. ORGANIC LETTERS[J]. 2020, 22(1): 88-92, http://dx.doi.org/10.1021/acs.orglett.9b04002.
[16] Liu, Huan, Pu, YuHan, Ren, JinWei, Li, ErWei, Guo, LiXia, Yin, WenBing. Genetic dereplication driven discovery of a tricinoloniol acid biosynthetic pathway in Trichoderma hypoxylon. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2020, 18(28): 5344-5348, https://www.webofscience.com/wos/woscc/full-record/WOS:000550965600006.
[17] 郭庆丰, 陈林, 尹震花, 张娟娟, 王彦波, 尹文兵. 大黄鱼共生菌Bacillus coagulans LL1103的代谢产物研究. 微生物学报[J]. 2020, 60(2): 387-396, http://lib.cqvip.com/Qikan/Article/Detail?id=7101183409.
[18] Nies, Jonas, Ran, Huomiao, Wohlgemuth, Viola, Yin, WenBing, Li, ShuMing. Biosynthesis of the Prenylated Salicylaldehyde Flavoglaucin Requires Temporary Reduction to Salicyl Alcohol for Decoration before Reoxidation to the Final Product. ORGANIC LETTERS[J]. 2020, 22(6): 2256-2260, http://dx.doi.org/10.1021/acs.orglett.0c00440.
[19] Xiang, Pan, LudwigRadtke, Lena, Yin, WenBing, Li, ShuMing. Isocoumarin formation by heterologous gene expression and modification by host enzymes. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2020, 18(26): 4946-4948, https://www.webofscience.com/wos/woscc/full-record/WOS:000546177200009.
[20] 蒲语涵, 刘欢, 陈国参, 郭莉霞, 尹文兵. 炭团木霉中非核糖体多肽基因NRPS1的功能研究. 微生物学报[J]. 2020, 60(10): 2350-2361, http://lib.cqvip.com/Qikan/Article/Detail?id=7103205209.
[21] Li, Wei, Yu, Jingwen, Li, Zixin, Yin, WenBing. Rational design for fungal laccase production in the model host Aspergillus nidulans. SCIENCE CHINA-LIFE SCIENCES[J]. 2019, 62(1): 84-94, http://lib.cqvip.com/Qikan/Article/Detail?id=6100172046.
[22] Zhang, Peng, Zhou, Shuang, Wa, Gang, An, Zhiqiang, Liu, Xingzhong, Li, Kuan, Yin, WenBing. Two transcription factors cooperatively regulate DHN melanin biosynthesis and development in Pestalotiopsis fici. MOLECULAR MICROBIOLOGY[J]. 2019, 112(2): 649-666, https://www.webofscience.com/wos/woscc/full-record/WOS:000482051300024.
[23] Fan, Jie, Liao, Ge, Kindinger, Florian, LudwigRadtke, Lena, Yin, WenBing, Li, ShuMing. Peniphenone and Penilactone Formation in Penicillium crustosum via 1,4-Michael Additions of ortho-Quinone Methide from Hydroxyclavatol to gamma-Butyrolactones from Crustosic Acid. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2019, 141(10): 4225-4229, https://www.webofscience.com/wos/woscc/full-record/WOS:000461537700012.
[24] 宋自力, 张伟, 廖头根, 汪世华, 李伟, 尹文兵. 血红密孔菌高产漆酶菌株的筛选及其对烟梗的生物降解. 菌物学报[J]. 2019, 38(3): 381-392, http://lib.cqvip.com/Qikan/Article/Detail?id=7001720995.
[25] 吴洪波, 陈林, 吕海宁, 刘欢, 汪世华, 尹文兵. 炭团木霉Trichoderma hypoxylon中一个新倍半萜. 菌物学报[J]. 2019, 533-538, http://lib.cqvip.com/Qikan/Article/Detail?id=74878884504849574852484857.
[26] Chen, Lin, Wu, GuangWei, Liu, Dong, Zhuang, WenYing, Yin, WenBing. Trichodermatides E and F from fungus Trichoderma applanatum. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH[J]. 2019, 21(7): 659-665, [27] Li, Wei, Yin, WenBing. Genetic mining of the "dark matter" in fungal natural products. SCIENCE CHINA-LIFE SCIENCESnull. 2019, 62(9): 1250-1252, http://lib.cqvip.com/Qikan/Article/Detail?id=7002865572.
[28] Ma, Ke, Zhang, Peng, Tao, Qiaoqiao, Keller, Nancy P, Yang, Yanlong, Yin, WenBing, Liu, Hongwei. Characterization and Biosynthesis of a Rare Fungal Hopane-Type Triterpenoid Glycoside Involved in the Antistress Property of Aspergillus fumigatus. ORGANIC LETTERS[J]. 2019, 21(9): 3252-3256, [29] Wei Li, WenBing Yin. Genetic mining of the "dark matter" in fungal natural products. 中国科学:生命科学英文版null. 2019, 62(9): 1250-1252, http://lib.cqvip.com/Qikan/Article/Detail?id=7002865572.
[30] Junlin Wang, Yanan Zhang, Huanhuan Liu, Yong Shang, Linjun Zhou, Penglin Wei, WenBing Yin, Zixin Deng, Xudong Qu, Qianghui Zhou. A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids. Nature Communications[J]. 2019, 10(1): 1-9, https://doaj.org/article/c3b8f0efe137499a839f5836ca824b91.
[31] Zhou, Shuang, Zhang, Peng, Zhou, Haichuan, Liu, Xingzhong, Li, ShuMing, Guo, Liangdong, Li, Kuan, Yin, WenBing. A new regulator RsdA mediating fungal secondary metabolism has a detrimental impact on asexual development in Pestalotiopsis fici. ENVIRONMENTAL MICROBIOLOGY[J]. 2019, 21(1): 416-426, http://dx.doi.org/10.1111/1462-2920.14473.
[32] 徐新然, 吕海宁, 周爽, 尹文兵. 真菌次级代谢转录调控研究进展. 菌物研究. 2019, 17(3): 125-137, http://lib.cqvip.com/Qikan/Article/Detail?id=7101033286.
[33] 魏鹏霖, 张鹏, 李伟, 汪世华, 尹文兵. 黄曲霉分生孢子色素合成基因pks1的鉴定及其对生长发育和侵染性的影响. 微生物学报[J]. 2019, 59(5): 965-977, http://lib.cqvip.com/Qikan/Article/Detail?id=7001975508.
[34] Li, Ruixin, Li, ZiXin, Ma, Ke, Wang, Gang, Li, Wei, Liu, HongWei, Yin, WenBing, Zhang, Peng, Liu, XingZhong. Strategy for efficient cloning of biosynthetic gene clusters from fungi. SCIENCE CHINA-LIFE SCIENCES[J]. 2019, 62(8): 1087-1095, http://lib.cqvip.com/Qikan/Article/Detail?id=74678871504849574856484948.
[35] Chen, Lin, Wu, HongBo, Liu, Huan, Li, Erwei, Ren, Jinwei, Wang, Wenzhao, Wang, Shihua, Yin, WenBing. Genetic dereplication of Trichoderma hypoxylon reveals two novel polycyclic lactones. BIOORGANIC CHEMISTRY[J]. 2019, 91: http://dx.doi.org/10.1016/j.bioorg.2019.103185.
[36] ZhiGuo Liu, Li Bao, HongWei Liu, JinWei Ren, WenZhao Wang, Long Wang, Wei Li, WenBing Yin. Chemical diversity from the Tibetan Plateau fungi Penicillium kongii and P. brasilianum. Mycology[J]. 2018, 9(1): 10-19, https://doaj.org/article/6c6faefe9ccb48d8bb3736a17c84b9cc.
[37] Ma, Zihui, Li, Wei, Zhang, Peng, Lyu, Haining, Hu, Youcai, Yin, WenBing. Rational design for heterologous production of aurovertin-type compounds in Aspergillus nidulans. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2018, 102(1): 297-304, https://www.webofscience.com/wos/woscc/full-record/WOS:000419119100025.
[38] Lin, Haizhou, Lyu, Haining, Zhou, Shuang, Yu, Jingwen, Keller, Nancy P, Chen, Lin, Yin, WenBing. Deletion of a global regulator LaeB leads to the discovery of novel polyketides in Aspergillus nidulans. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2018, 16(27): 4973-4976, https://www.webofscience.com/wos/woscc/full-record/WOS:000438393200007.
[39] Li, Wei, Fan, Aili, Wang, Long, Zhang, Peng, Liu, Zhiguo, An, Zhiqiang, Yin, WenBing. Asperphenamate biosynthesis reveals a novel two-module NRPS system to synthesize amino acid esters in fungi. CHEMICAL SCIENCE[J]. 2018, 9(9): 2589-2594, https://www.webofscience.com/wos/woscc/full-record/WOS:000431087700025.
[40] Yang, Yanlong, Zhang, Yuting, Zhang, Shasha, Chen, Qingwen, Ma, Ke, Bao, Li, Tao, Yong, Yin, Wenbing, Wang, Guodong, Liu, Hongwei. Identification and Characterization of a Membrane-Bound Sesterterpene Cyclase from Streptomyces somaliensis. JOURNAL OF NATURAL PRODUCTS[J]. 2018, 81(4): 1089-1092, https://www.webofscience.com/wos/woscc/full-record/WOS:000431165100047.
[41] Wang, Yan, Wang, Liuqing, Wu, Fan, Liu, Fei, Wang, Qi, Zhang, Xiaoling, Selvaraj, Jonathan Nimal, Zhao, Yueju, Xing, Fuguo, Yin, WenBing, Liu, Yang. A Consensus Ochratoxin A Biosynthetic Pathway: Insights from the Genome Sequence of Aspergillus ochraceus and a Comparative Genomic Analysis. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2018, 84(19): https://www.webofscience.com/wos/woscc/full-record/WOS:000446204500007.
[42] Wang, Songshan, Cui, Hua, Ye, Jin, Wu, Yu, Wang, Songxue, Yin, Wenbing. Identification and Determination of Rubrofusarin, Rubrofusarin Isomer, and Their Quinone Forms in Grains Using High-Resolution Mass Spectrometry. ACS OMEGA[J]. 2018, 3(11): 15924-15932, https://doaj.org/article/df21dd115d6248e89050aa62ae4af04d.
[43] Zeng, Guohong, Zhang, Peng, Zhang, Qiangqiang, Zhao, Hong, Li, Zixin, Zhang, Xing, Wang, Chengshu, Yin, WenBing, Fang, Weiguo. Duplication of a Pks gene cluster and subsequent functional diversification facilitate environmental adaptation in Metarhizium species. PLOS GENETICS[J]. 2018, 14(6): http://dx.doi.org/10.1371/journal.pgen.1007472.
[44] Liu, Li, Bao, Li, Wang, Long, Ma, Ke, Han, Junjie, Yang, Yanlong, Liu, Ruixing, Ren, Jinwei, Yin, Wenbing, Wang, Wenzhao, Liu, Hongwei. Asperorydines A-M: Prenylated Tryptophan-Derived Alkaloids with Neurotrophic Effects from Aspergillus oryzae. JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 83(2): 812-822, https://www.webofscience.com/wos/woscc/full-record/WOS:000423252300026.
[45] Liu, Huan, Wang, Gang, Li, Wei, Liu, Xingzhong, Li, Erwei, Yin, WenBing. A highly efficient genetic system for the identification of a harzianum B biosynthetic gene cluster in Trichoderma hypoxylon. MICROBIOLOGY-SGM[J]. 2018, 164(5): 769-778, https://www.webofscience.com/wos/woscc/full-record/WOS:000438759300005.
[46] Li, Wei, Ma, Zihui, Chen, Lin, Yin, WenBing. Synthesis and production of the antitumor polyketide aurovertins and structurally related compounds. APPLIED MICROBIOLOGY AND BIOTECHNOLOGYnull. 2018, 102(15): 6373-6381, [47] Liu, Li, Wang, Long, Bao, Li, Ren, Jinwei, Basnet, Buddha Bahadur, Liu, Ruixing, He, Luwei, Han, Junjie, Yin, WenBing, Liu, Hongwei. Versicoamides F-H, Prenylated lndole Alkaloids from Aspergillus tennesseensis. ORGANIC LETTERS[J]. 2017, 19(4): 942-945, [48] Zheng, Yanjing, Wang, Xiuna, Zhang, Xiaoling, Li, Wei, Liu, Gang, Wang, Shihua, Yan, Xiufeng, Zou, Huixi, Yin, WenBing. COP9 signalosome subunit PfCsnE regulates secondary metabolism and conidial formation in Pestalotiopsis fici. SCIENCE CHINA-LIFE SCIENCES[J]. 2017, 60(6): 656-664, https://www.webofscience.com/wos/woscc/full-record/WOS:000404775400009.
[49] Zheng Yanjing, Wang Xiuna, Zhang Xiaoling, Li Wei, Liu Gang, Wang Shihua, Yan Xiufeng, Zou Huixi, Yin WenBing. COP9 signalosome subunit PfCsnE regulates secondary metabolism and conidial formation in Pestalotiopsis fici. Science China Life Sciences[J]. 2017, [50] Zhang, Peng, Wang, Xiuna, Fan, Aili, Zheng, Yanjing, Liu, Xingzhong, Wang, Shihua, Zou, Huixi, Oakley, Berl R, Keller, Nancy P, Yin, WenBing. A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici. MOLECULAR MICROBIOLOGY[J]. 2017, 105(3): 469-483, http://dx.doi.org/10.1111/mmi.13711.
[51] Yang, Yanlong, Zhang, Shasha, Ma, Ke, Xu, Yuxing, Tao, Qiaoqiao, Chen, Yihua, Chen, Juan, Guo, Shunxing, Ren, Jinwei, Wang, Wenzhao, Tao, Yong, Yin, WenBing, Liu, Hongwei. Discovery and Characterization of a New Family of Diterpene Cyclases in Bacteria and Fungi. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2017, 56(17): 4749-4752, http://ir.kib.ac.cn/handle/151853/50995.
[52] 刘宏伟. Discovery and characterization of the UbiA proteins as a new family of diterpene cyclases in bacteria and fungi. Angew. Chem. Int. Ed.. 2017, [53] 刘宏伟. New Decalin-Containing Tetramic acids and 4-hydroxy-2-pyridones with Antimicrobial and Cytotoxic Activity from the Fungus Coniochaeta cephalothecoides Collected in Tibetan Plateau (Medog). The Journal of Organic Chemistry. 2017, [54] Feng, Jin, Zhang, Peng, Cui, Yinglu, Li, Kai, Qiao, Xue, Zhang, YingTao, Li, ShuMing, Cox, Russell J, Wu, Bian, Ye, Min, Yin, WenBing. Regio- and Stereospecific O-Glycosylation of Phenolic Compounds Catalyzed by a Fungal Glycosyltransferase from Mucor hiemalis. ADVANCED SYNTHESIS & CATALYSIS[J]. 2017, 359(6): 995-1006, https://www.webofscience.com/wos/woscc/full-record/WOS:000397584000013.
[55] Han, Junjie, Liu, Congcong, Li, Li, Zhou, Hui, Liu, Li, Bao, Li, Chen, Qian, Song, Fuhang, Zhang, Lixin, Li, Erwei, Liu, Ling, Pei, Yunfei, Jin, Cheng, Xue, Yanfen, Yin, Wenbing, Ma, Yanhe, Liu, Hongwei. Decalin-Containing Tetramic Acids and 4-Hydroxy-2-pyridones with Antimicrobial and Cytotoxic Activity from the Fungus Coniochaeta cephalothecoides Collected in Tibetan Plateau (Medog). JOURNAL OF ORGANIC CHEMISTRY[J]. 2017, 82(21): 11474-11486, https://www.webofscience.com/wos/woscc/full-record/WOS:000414724000016.
[56] Fan, Aili, Mi, Wubin, Liu, Zhiguo, Zeng, Guohong, Zhang, Peng, Hu, Youcai, Fang, Weiguo, Yin, WenBing. Deletion of a Histone Acetyltransferase Leads to the Pleiotropic Activation of Natural Products in Metarhizium robertsii. ORGANIC LETTERS[J]. 2017, 19(7): 1686-1689, https://www.webofscience.com/wos/woscc/full-record/WOS:000398985800049.
[57] 尹文兵. Regio- and stereospecific O-glycosylation of phenolic compounds catalysed by a fungal glycosyltransferase from Mucor hiemalis. Adv. Synth. Catal.. 2017, [58] Zheng, Yanjing, Ma, Ke, Lyu, Haining, Huang, Ying, Liu, Hongwei, Liu, Ling, Che, Yongsheng, Liu, Xingzhong, Zou, Huixi, Yin, WenBing. Genetic Manipulation of the COP9 Signalosome Subunit PfCsnE Leads to the Discovery of Pestaloficins in Pestalotiopsis fici. ORGANIC LETTERS[J]. 2017, 19(17): 4700-4703, https://www.webofscience.com/wos/woscc/full-record/WOS:000409566400073.
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[61] 郑艳静, 王秀娜, 章小灵, 李伟, 刘钢, 汪世华, 阎秀峰, 邹慧熙, 尹文兵. COP9信号小体亚基CsnE对无花果拟盘多毛孢生长发育和次级代谢的影响. 中国科学. 生命科学[J]. 2017, 47(7): 750-758, [62] Liu Li, Wang Long, Bao Li, Ren Jinwei, Basnet Buddha Bahadur, Liu Ruixing, He Luwei, Han Junjie, Yin WenBing, Liu Hongwei. Versicoamides F–H, Prenylated Indole Alkaloids from Aspergillus tennesseensis. Organic Letters[J]. 2017, [63] Wang, Gang, Liu, Zhiguo, Lin, Runmao, Li, Erfeng, Mao, Zhenchuan, Ling, Jian, Yang, Yuhong, Yin, WenBing, Xie, Bingyan. Biosynthesis of Antibiotic Leucinostatins in Bio-control Fungus Purpureocillium lilacinum and Their Inhibition on Phytophthora Revealed by Genome Mining. PLOS PATHOGENS[J]. 2016, 12(7): https://doaj.org/article/b1ef4298cc8748938fe4aa0cda3e8fa0.
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[67] Wu, Guangwei, Zhou, Haichuan, Zhang, Peng, Wang, Xiuna, Li, Wei, Zhang, Weiwei, Liu, Xingzhong, Liu, HongWei, Keller, Nancy P, An, Zhiqiang, Yin, WenBing. Polyketide Production of Pestaloficiols and Macrodiolide Ficiolides Revealed by Manipulations of Epigenetic Regulators in an Endophytic Fungus. ORGANIC LETTERS[J]. 2016, 18(8): 1832-1835, https://www.webofscience.com/wos/woscc/full-record/WOS:000374436800031.
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[74] 尹文兵. Structurally diverse sesquiterpenes produced by a Chinese Tibet fungus Stereum hirsutum and their cytotoxic and immunosuppressant activities.. Org. Lett.. 2015, [75] Wang, Lin, Feng, Yu, Tian, Jianqing, Xiang, Meichun, Sun, Jingzu, Ding, Jianqing, Yin, WenBing, Stadler, Marc, Che, Yongsheng, Liu, Xingzhong. Farming of a defensive fungal mutualist by an attelabid weevil. ISME JOURNAL[J]. 2015, 9(8): 1793-1801, http://202.127.146.157/handle/2RYDP1HH/231.
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[79] Wang, Xiuna, Wu, Fan, Liu, Ling, Liu, Xingzhong, Che, Yongsheng, Keller, Nancy P, Guo, Liyun, Yin, WenBing. The bZIP transcription factor PfZipA regulates secondary metabolism and oxidative stress response in the plant endophytic fungus Pestalotiopsis fici. FUNGAL GENETICS AND BIOLOGY[J]. 2015, 81: 221-228, http://dx.doi.org/10.1016/j.fgb.2015.03.010.
[80] XuMing Mao, Wei Xu, Dehai Li, WenBing Yin, YitHeng Chooi, YongQuan Li, Yi Tang, Youcai Hu. Epigenetic Genome Mining of an Endophytic Fungus Leads to Pleiotropic Biosynthesis of Natural Products. Angewandte Chemie (International ed. in English). 2015, 54(26): 7592-7596, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487767/.
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[84] Hu, Youcai, Dietrich, David, Xu, Wei, Patel, Ashay, Thuss, Justin A J, Wang, Jingjing, Yin, WenBing, Qiao, Kangjian, Houk, K N, Vederas, John C, Tang, Yi. A carbonate-forming Baeyer-Villiger monooxygenase. NATURE CHEMICAL BIOLOGY[J]. 2014, 10(7): 552-554, https://www.webofscience.com/wos/woscc/full-record/WOS:000337871200012.
[85] Wiemann, Philipp, Lechner, Beatrix E, Baccile, Joshua A, Velk, Thomas A, Yin, WenBing, Bok, Jin Woo, Pakala, Suman, Losada, Liliana, Nierman, William C, Schroeder, Frank C, Haas, Hubertus, Keller, Nancy P. Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus. FRONTIERS IN MICROBIOLOGY[J]. 2014, 5: https://doaj.org/article/5c21472d0b594b479a888c6dbcc0e41e.
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[87] Yin, WenBing, Chooi, Yit Heng, Smith, Adam R, Cacho, Ralph A, Hu, Youcai, White, Theodore C, Tang, Yi. Discovery of Cryptic Polyketide Metabolites from Dermatophytes Using Heterologous Expression in Aspergillus nidulans. ACS SYNTHETIC BIOLOGY[J]. 2013, 2(11): 629-634, https://www.webofscience.com/wos/woscc/full-record/WOS:000327175400001.
[88] Yin, WenBing, Baccile, Joshua A, Bok, Jin Woo, Chen, Yiming, Keller, Nancy P, Schroeder, Frank C. A Nonribosomal Peptide Synthetase-Derived Iron(III) Complex from the Pathogenic Fungus Aspergillus fumigatus. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2013, 135(6): 2064-2067, https://www.webofscience.com/wos/woscc/full-record/WOS:000315080100009.
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[92] 尹文兵. Reconstruction of pyrrolo[2,3-b]indoles carrying an a-configured reverse C3-dimethylallyl moiety by using recombinant enzymes. Org. Biomol. Chem.. 2010, [93] 尹文兵. Preparation of pyrrolo[2,3-b]indoles carrying a ?-configured reverse C3-dimethylallyl moiety by using a recombinant prenyltransferase CdpC3PT. Org. Biomol. Chem.. 2010, [94] 王璐, 尹文兵, 李书明, 刘晓晴. 异戊烯基化吲哚类生物碱的化学酶合成. 中国生物化学与分子生物学报[J]. 2009, 580-584, http://lib.cqvip.com/Qikan/Article/Detail?id=30758472.
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科研活动

   
科研项目
(1) “****”启动,主持,院级级,2014-01--2015-07