Lijuan Zhang, Professor of Radiology

Shenzhen Institutes of Advanced Technology

Chinese Academy of Sciences

1068 Xueyuan Blvd, University Town

Shenzhen, China 518055


Telephone: 0755-86392247

Research Areas

Neuroimaging; MRI; Neuroscience


2002-2005: Weill Medical College of Cornell University, New York, NY, USA. Postdoc Research Fellow.

1995-1998: PLA Postgraduate Medical School, Beijing, China. Master of Medical Imaging.

1990-1995: Harbin Medical University, Harbin, China. Bachelor of Medicine.


2014-Current: Professor, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China.

2011-2013: Associate Professor, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences.

2009-2010: Assistant Professor, Mount Sinai Medical School, New York, NY, USA.

2005-2009: Research Associate, Weill Medical College of Cornell University, New York, NY, USA.

2002-2005: Postdoctoral Research Fellow, Weill Medical College of Cornell University, New York, NY, USA.

1998-2002: Affiliated Hospital of 1st Millitary Medical University, Guangzhou, China.

Teaching Experience

1. Diagnostic Radiology for the 2nd to 4th year medical students;

2. Essentials of Neuroimaging for postgraduate students.


1. Siqi Cai, Zhifeng Shi, Chunxiang Jiang, Kai Wang, Liang Chen, Lin Ai, Lijuan Zhang. Hemispheric specific functional remodeling and its relevance to tumor malignancy of cerebral glioma based on resting-state functional network analysis. Front Neurosci 2021; 14: 611075.

2. Wu Zhou, Wanwei Jian, Xiaoping Cen, Lijuan Zhang, Hui Guo, Zaiyi Liu, Changhong Liang, Guangyi Wang. Prediction of Microvascular invasion of hepatocellular carcinoma with Contrast-enhanced MR using 3D Convolutional Neural Networks. Front. Oncol.

3.  Lijuan Zhang. Glioma characterization based on magnetic resonance imaging:challenge overview and future perspective. Glioma 2020; 3: 61-66.

4. Guangyi Wang, Wanwei Jian, Xiaoping Cen, Lijuan Zhang, Hui Guo, Zaiyi Liu, Changhong Liang, Wu Zhou. Prediction of microvascular invasion of HCC based on preoperative diffusion weighted MR using deep learning. Acad Radiology 2020;

5.  Chunxiang Jiang, Li Yi, Siqi Cai, Lijuan Zhang*. Ischemic stroke in Pontine and corona radiate: Location specific impairment of neural network investigated with Resting state Fmri. Frontiers in Neurology 2019;

6.   Wu Zhou, Guangyi Wang, Guoxi Xie, Lijuan Zhang. Grading of hepatocellular carcinoma based on diffusion weighted images with multiple b-values using convolutional neural networks. Medical Physics 2019;46(9): 3951-3960.

7.  Xia J, Yang Y, Hu C, Meng R, Jiang Q, Liu R, Yu Y, Sheng Z, Yan F, Zhang L, Shi Z, Zheng H, Qiu W. Evaluation of Brain Tumor in Small Animals Using Plane Wave-Based Power Doppler Imaging. Ultrasound Med Biol. 2019 Mar;45(3):811-822.

8.   Shi Su, Na Lu, Lin Jia, Xiaojing Long, Chunxiang Jiang, Hang Zhang, Ye Li,  Kaibao Sun, Rong Xue, Dharmakumar R, Lijuan Zhang, Xin Liu, Guoxi Xie. High Spatial Resolution BOLD fMRI Using Simultaneous Multislice Excitation with Echo-Shifting Gradient Echo at 7 Tesla. MRI 2018; doi: 10.1016/j.mri.2018.08.019.

9.  Xiaojing Long, Chunxiang Jiang, Lijuan Zhang*. Morphological Biomarker Differentiating MCI Converters from Non-converters: Longitudinal Evidence Based on Hemispheric Asymmetry. Behavioural Neurology 2018; 3954101.

10. LijXiaojing Long, Lifang Chen, Chunxiang Jiang, Lijuan Zhang*. Prediction and classification of Alzheimer disease based on quantification of MRI deformation. PloS One 2017; 12(3):e0173372.

11. Wu ZhouLijuan Zhang*Kaixin WangShuting ChenGuangyi WangZaiyi LiuChanghong Liang. Malignancy Characterization of Hepatocellular Carcinomas Based on Texture Analysis of Contrast-Enhanced MR Images. JMRI 2017; 45:1476-1484.

12.  Chunxiang Jiang, Li Yi, Shi Su, Caiyun Shi, Guoxi Xie, Lijuan Zhang*. Diurnal variations in neural activity of healthy human brain decoded with resting state blood oxygen level dependent Fmri. Frontier Hum Neurosci 2016; 10:634.

13.  Lijuan Zhang, Xin Liu, Zhaoyang Fan, Na Zhang, Yiu-cho Chung, Weiqi Liao, Hairong Zheng, Debiao Li. Noncontrast MRA of Pedal arteries in Type II diabetes: effect of disease load on vessel visibility. Academic Radiology 2015; 22:513-519.

14. Hang Zhang, Lijuan Zhang, Yufeng Zang. Fluctuation amplitude and local synchronization of brain activity in the ultra-low frequency band: an fMRI investigation of continuous feedback of finger force. Brain Research 2015; 1629104-112.

15. Caiyun Shi, Guoxi Xie, Xiaoyong Zhang, Shi Su, Yongqin Zhang, Lijuan Zhang, Bensheng Qiu, Xin Liu. High spatiotemporal resolution fMRI using partial separability model. Bio-Medical Materials and Engineering 2015; 26: S1439-S1446.

16.  Lei Zhang, Na Zhang, Jun Wu, Lijuan Zhang, Yanyan Huang, Xin Liu, Yiu-Cho Chung. High resolution three dimensional intracranial arterial wall imaging at 3T using T1 weighted SPACE. MRI 2015; 33(9):1026-34.

17.  Wu Zhou, Lijuan Zhang*, Yaoqin Xie, Changhong Liang. A novel technique for prealignment in multimodality medical image registration. Biomed Res Int. 2014; 2014: 726852.

18.  Weiqi Liao, Xiaojing Long, Chunxiang Jiang, Yanjun Diao, Xin Liu, Hairong Zheng, Lijuan Zhang*. Discerning mild cognitive impairment and Alzheimer disease from normal aging: morphologic characterization based on univaritate and multivariate models. Academic Radiology 2014; 21:597-604.

19. Chunxiang Jiang, Lijuan Zhang*, Chao Zou, Xiaojing Long, Xin Liu, Hairong Zheng, Weiqi Liao, Yanjun Diao. Diurnal Microstructural variations of Healthy Adult Brain revealed by Diffusion tensor imaging. PLOS ONE 2014; DOI: 10.1371/journal.pone.0084822.

20. Xiaojing Long, Lijuan Zhang*, Weiqi Liao, Chunxiang Jiang, Bensheng Qiu and Alzheimer’s disease neuroimaging initiative. Distinct laterality alterations distinguish mild cognitive impairment and Alzheimer’s disease from healthy aging: statistical parametric mapping with high resolution MRI. Human Brain Mapping 2013;34:3400-3410; 

21.  Xiaojing Long, Weiqi Liao, Chunxiang Jiang, Dong Liang, Bensheng Qiu, Lijuan Zhang*. Healthy Aging: An automatic analysis of global and regional morphological alterations of human brain. Academic Radiology 2012; 19(7):785-793. 

22.  Lijuan Zhang, David Yankelevitz, Claudia Henschke, Daryl Carter, Anthony P. Reeves, et al. Internal Growth of Non-solid Nodules: Radiologic-Pathologic Correlation. Radiology 2012; 263:279-286).

23.  Na Zhang, Lijuan Zhang, Bensheng Qiu, Li Meng, Xiaoyi Wang, Bob Hou. Correlation of volume transfer coefficient K trans with histopathologic grades of gliomas. JMRI 2012; 36(2):355-363.

24. AO Farooqi, M.Cham, Lijuan Zhang, MB. Beasley, JH. M. Austin , A.Miller , J. J Zulueta , H. Roberts, C. Enser, SJ. Kao, MK. Thorsen, JP. Smith, DM. Libby, R.Yip, DF. Yankelevitz, CI. Henschke. Lung Cancer Associated with Cystic Airspaces. AJR 2012; 199(4):781-786.

25.  Chunxiang Jiang, Xiang Li, Fei Yan, Zhanhui Wang, Qiaofeng Jin, Feiyan Cai, Ming Qian, Xin Liu, Lijuan Zhang, Hairong Zheng.  Microfluidic Assisted Formation of Multifunctional Monodisperse Microbubbles for Diagnostics and Therapeutics. Micro & Nano Letters 2011; 6: 417-421.

26.  Yao Huang, Dong ming Xu, Artit Jirapatnakul, Anthony P. Reeves, Ali Farooqi, Li juan Zhang, et al. CT- and computer-based features of small hamartomas. Clinical Imaging 2011; 35: 116-122. 

27. Yin Wu, Lijuan Zhang, Chao Zou, Hung-Fat Tse, Ed X. Wu. Transmural Heterogeneity of Left Ventricular Myocardium Remodeling in Postinfarct Porcine Model Revealed by MR Diffusion Tensor Imaging. JMRI 2011; 34(1): 43-49.

28.  Lijuan Zhang, David F. Yankelevitz MD,Claudia I. Henschke PhD, MD, Artit C. Jirapatnakul, PhD, Anthony P. Reeves PhD,  Darryl Carter MD. Zone of transition: A Potential Source of Error in Tumor Volume Estimation. Radiology 2010; 256: 633-639.

29. Lijuan Zhang, David Yankelevitz, Claudia Henschke, Anthony Reeves, et al. Variations in Vascular Distribution in Small Lung Cancer. Lung Cancer 2010; 68: 389-393.

30.  Madeline Vazquez, Darryl Carter, Elizabeth Brambilla, Lijuan Zhang, et al. Solitary and Multiple Resected Adenocarcinomas after CT Screening for Lung Cancer: Histopathologic Features and their Prognostic Implications. Lung Cancer 2009; 64: 148-154. 

31. Rajbir K. Gill, Madeline F. Vazquez, Arin Kramer, Megan Hames, Lijuan Zhang, Kerstin Heselmeyer-Haddad, Thomas Ried, Konstantin Shilo, Claudia Henschke, David Yankelevitz, Jin Jen. The Use of Genetic Markers to Identify Lung Cancer in Fine Needle Aspiration Samples. Clinical Cancer Research 2008; 14, 7481-7487.

32. S. M. Hersch, S. Gevorkian, K. Marder, C. Moskowitz, A. Feigin, M. Cox, P. Como, C. Zimmerman, M. Lin, MD, Lijuan Zhang, A. M. Ulug, M. F. Beal, W. Matson, M. Bogdanov, E. Ebbel, A. Zaleta, Y. Kaneko, B. Jenkins, N. Hevelone, H. Zhang, H. Yu, D. Schoenfeld, R. Ferrante, H. D. Rosas. Creatine in Huntington disease is safe, tolerable, elevates brain NAA, and reduces serum 8OH2’dG. Neurology 2006; 66: 250-252.

33. Lijuan Zhang, Melanie Harrison, Linda A. Heier, Robert D. Zimmerman, Lisa Ravdin, Michael Lockshin, Aziz M. Uluğ. Diffusion changes in patients with systemic lupus erythematosus. Magn Reson Imaging 2007; 3:399-405.

34. Michael H. Chappell, Aziz M.Ulug, Lijuan Zhang, Marcus H. Heitger, Barry D. Jordan, Robert D. Zimmerman, Richard Watts. Distribution of microstructural damage in the brains of professional boxers: A diffusion MRI study. JMRI. 2006; 24(3):537-42.

35. Lijuan Zhang, Linda A. Heier, Robert D. Zimmerman, et al. Diffusion anisotropy changes in the brains of professional boxers. AJNR 2006; 27(9):2000-4.

36. Lijuan Zhang, Kathleen M. Thomas, Matthew C. Davidson, B.J. Casey, Linda A. Heier, Aziz M. Uluğ. MR Quantitation of Volume and Diffusion changes in the Developing Brain. AJNR 2005; 26:45-49.

37.  Lijuan Zhang, Lisa D. Ravdin, Norman Relkin, Robert D. Zimmerman, Aziz M.Ulug. Increased Diffusion in the Brain of Professional Boxers: A Preclinical Sign of Traumatic Brain Injury? AJNR 2003; 24: 52-57.     

38. Lijuan Zhang, Aziz M. Ulug, Robert D. Zimmerman, Michael Lin, Michael Rubin, M. Flint Beal. The diagnostic utility of FLAIR imaging in clinically verified amyotrophic lateral sclerosis. JMRI 2003; 17: 521-527.

Research Interests

Applying auantitative functional MRI, MR Spectroscopy, Diffusion Tensor Imaging and chemical exchange saturation transfer to probe brain physiology and pathology, and promote the translational application of new magnetic resonance imaging techniques in researches of ischemic stroke, cerebral glioma and sleep disorder. 


Annual conferences of ISMRM and OHBM. 



蔡思琦  硕士研究生  085208-电子与通信工程  

孟锐  硕士研究生  071010-生物化学与分子生物学  

周诗辉  硕士研究生  085210-控制工程  


姜春香  博士研究生  071010-生物化学与分子生物学  

蔡思琦  博士研究生  081104-模式识别与智能系统  

蒲尧  硕士研究生  085404-计算机技术