电子邮件: wangzz@impcas.ac.cn
通信地址: 中科院近物所
邮政编码: 730000
研究领域
辐射损伤分子机理、辐射损伤药物防护
教育背景
工作经历
2007-07--今 中科院近物所 副研究员
1995-06--2000-06 中国农科院兰州畜牧与兽药研究所 研实员
科研活动
主持和参与的科研项目:
重离子辐射与模拟微重力复合作用致小鼠造血损伤及其机理研究,2019.01—2024.12
酵母β-葡聚糖对空间重离子辐射生物损伤防护效应及相关机理研究,2016.01--2020.12
空间单粒子辐射危害效应及其分子机理研究, 2012.01--2016.06
旁效应细胞对重离子辐照细胞的反馈调节作用研究, 2012.01--2015.06
研究成果
The mechanisms for the radioprotective effect of β-D-glucan on high linear-energy-transfer carbon ion irradiated mice. Int J Bio Macrimol, 2019, 131: 282-292. (通讯作者)
Transcriptional response of murine bone marrow cells to total-body carbon-ion irradiation. Mutat Res Gen Tox En, 2019, 839: 49-58. (通讯作者)
碳离子全身辐照致小鼠造血系统的损伤,癌变·畸变·突变,2018, 30(2): 109-113(通讯作者)
酵母β-葡聚糖对人静脉内皮细胞辐射损伤的防护作用,辐射研究与辐射工艺学报,2018:36(4): 040201(1-7)(通讯作者)
羧甲基-β-1,3-葡聚糖对人肝癌HepG2细胞的放射增敏作用,原子核物理评论,2017,34 (4): 797-802(第2作者)
羧甲基-1,3-葡聚糖对人B淋巴母细胞的辐射防护作用,辐射研究与辐射工艺学报,2016,34(2):020205(1-7)(第2作者)
内质网应激对碳离子辐照宫颈癌 HeLa 细胞的影响,原子核物理评论, 2015,32(2):236-241(第2作者)
The role of autophagy in cell survival induced by high energy carbonions irradiation in the plateau region, Nuclear Science and Techniques, 2014,25(3): 030303(1-6)(通讯作者)
Simulated microgravity increases heavy ion radiation-induced apoptosis in human B lymphoblasts, Life Sciences, 2014, 87: 123-128(第8作者)
Relationship between plant growth and cytological effect in root apical meristem after exposure of wheat dry seeds to carbon ion beams, Nuclear Instruments and Methods in Physics Research B, 2013, 156(4): 514-517 (第2作者)
The local skin dose conversion coefficients of electrons, protons and alpha particles calculated using the GEANT4 code, Radiation Protection Dosimetry, 2013, 156(4): 514–517 (第3作者)
Chromsome aberration induced by accelerated carbon ions with shielding, 生物物理学报, 2013, 29: 48(第1作者)
The Effects of Carbon‐ion Irradiation Combined with 3‐MA on Apoptosis in Hela Cells, 生物物理学报, 2013, 29: 049(第2作者)
The Effect of Different Radiation Quality on the Survival of HepG2 Cells under Normoxia and Hypoxia, 生物物理学报, 2013, 29:050(第3作者)
维拉帕米对HeLa 细胞12 C6+ 离子辐射敏感性的影响. 药物生物技术. 2012,19( 3) : 238 - 241(第4作者)
Cytogenetic effects induced by accelerated carbon ions with shielding, Radiation and Environmental Biophysics, 2011, 50 (3): 383-387 (第1作者)
重离子辐射诱导染色体畸变研究进展,辐射研究与辐射工艺学报,2011,29(4):193-196 (第1作者)
模拟微重力效应对辐射致细胞DNA损伤修复效应的影响,原子核物理评论,2011, 28(1):114-117(第3作者)
面向空间高能重离子与辐射屏蔽材料的反应截面地基研究,原子核物理评论,2011,28(1):88-96(第4作者)
ring chromosome aberrations in human lymphocytes induced by 5 - 20 Gy carbon ion irradiation, Nuclear Science and Techniques, 2010, 21(6): 362–365 (第1作者)
碳离子辐照诱导人外周血淋巴细胞染色体畸变的时间和剂量效应, 癌变·畸变·突变,2010, 21 (1): 35-38(第1作者)
粒子微束辐射生物学效应研究进展,辐射防护通讯,2010,30(1):17-21(第1作者)
空间辐射生物学研究进展,原子核物理评论,2010,27(2):86-91 (第3作者)
X射线辐照后人肝细胞、肝癌细胞存活与端粒酶活性关系的研究,辐射研究与辐射工艺学报,2010,28(2):119-123(第6作者)
Prematurely condensed chromosome fragments in human lymphocytes induced by high doses of high-linear-energy-transfer irradiation, Mutation Research, 2009, 679 (1-2): 9-12 (第1作者)
Micronuclei induction in human lymphocytes induced by carbon ions exposion along the penetrate depth of ions in water, NIMB, 2009, 267: 2521–2524 (第1作者)
电离辐射旁效应的研究方法概述,辐射研究与辐射工艺学报,2009,27(4):193-200 (第1作者)
Relationship between cellular radio-sensitivity and naked DNA damage in mammalian cells exposed to heavy ions, Nuclear Science and Techniques, 2009, 20(6): 349-353 (第3作者)
Radiosensitivity of hepatoma cell lines and human normal liver cell lines exposed in vitro to carbon ions and argon ions at the HIRFL, NIMB, 2009, 267: 1837-1840(第3作者)
不同LET射线对细胞的生物学效应,原子核物理评论, 2009, 26(3): 259-262 (第4作者)
G2-Chromosome fragments after irradiation with carbon ions, 生物物理学报, 2009, 25: 480 (第1作者)
Study of the effect of dose-rate on carbon ions induced chromosome damage to human lymphocytes, 生物物理学报, 2009, 25: 463(第2作者)
ATM蛋白表达与四种肿瘤细胞的辐射敏感性的关系,生物物理学报,2009,25:481(第3作者)
环境中氧含量水平对细胞辐射敏感性的影响,生物物理学报,2009,25:457(第3作者)
Chromatid-type aberrations following irradiation in G0 lymphocytes with heavy ions. Mutation Research-----Fundamental and Molecular Mechanismes of Mutagenesis, 2007, 617 (1-2): 98-103 (第1作者)
Biodosimetry estimate for high-LET irradiation, Radiat Environ Biophys, 2007, 46(3): 229-235(第1作者)
Comparison of clonogenic assay with premature chromosome condensation assay in prediction of human cell radiosensitivity, World J Gastroenterol, 2006, 12(16): 2601-2605 (第1作者)
G2 chromosome radiosensitivity in human tumor cells afterγ-rays irradiation, Nuclear Science and Techniques, 2006, 17(5): 268–271 (第1作者)
γ射线诱导人卵巢癌细胞G2-染色体的畸变与修复,核技术,2006,29(8):597-600 (第1作者)
γ射线对肝癌细胞G2-染色体的原初损伤,原子核物理评论, 2006,23(1):43-45(第1作者)
肝癌细胞辐射敏感性与G2期染色体畸变的线性关系及其应用研究,中华放射医学与防护杂志,2006,26(5):431-434 (第1作者)
染色体畸变与人肿瘤细胞辐射敏感性关系的研究进展,中华放射医学与防护杂志,2005,25(3):293-295(第1作者)
Study in vitro and in vivo of nociceptin/Orpharnin FQ(1-13)NH2 analogues substituting N-Me-Gly for Gly2 or Gly3,Peptides, 2004, 25(8): 1349-1354(第5作者)
Effects of nociceptin (13-17) in pain modulation at supraspinal level in mice, Neurosci Lett, 2002, 331(2): 95-98(第2作者)
[Nphe1]nociceptin(1-13)NH2 antagonizes nociceptin-induced hypotension, bradycardia and hindquarters vasodilation in the anesthetized rat, Can J Physiol Pharmacol,2002,80(1):31-35(第3作者)
痛稳素和痛稳素(10~17)对 孤啡肽对抗内吗啡肽-1及内吗啡肽-2镇痛作用,药学学报,2002,37(11):837-840(第3作者)
半枝莲多糖和白花蛇舌草多糖抗衰老作用的研究,中国兽医医药杂志,1999,4:5-7(第1作者)