基本信息
于军  男  博导  中国科学院北京基因组研究所(国家生物信息中心)
电子邮件: junyu@big.ac.cn
通信地址: 朝阳区北辰西路1号院104#
邮政编码: 100101

招生信息

   
招生方向
脊椎动物基因组学,基因组结构与功能,表型可塑性研究
生物信息学,基因功能网络与结构
研发DNA和RNA新测序技术

教育背景

1984-09--1990-06   纽约大学医学院   博士学位

工作经历

   
工作简历
1998-03~现在, 中国科学院北京基因组研究所, 研究员
1993-07~2000-03,美国华盛顿大学基因组中心, Senior Fellow
1990-07~1993-06,纽约大学医学院泌尿系, Research Assistant Professor
1984-09~1990-06,纽约大学医学院, 博士学位

教授课程

学术道德与学术写作规范
基因组学概述
生命组学
基因组学
发现生命奥秘
英文生物论文写作
生物专业英语论文写作基本方法与技巧概要
生物信息学进展系列讲座
公共关系

专利与奖励

   
奖励信息
(1) 2014年中国分析测试协会科学技术奖, 一等奖, 其他, 2014
(2) 2013年国家专利优秀奖, , 国家级, 2013
(3) 2012年度发展中国家科学院农业奖, , 其他, 2012
专利成果
( 1 ) 用于敲除人 BTF 基因的sgRNA 序列及其敲除方法, 2015, 第 4 作者, 专利号: 201510515835.5

出版信息

   
发表论文
(1) On the ultimate finishing line of the Human Genome Project, The Innovation, 2021, 第 1 作者
(2) Gut lactate-producing bacteria promote CD4 T cell recovery on Anti-retroviral therapy in HIV-infected patients, Computational and Structural Biotechnology Journal, 2021, 其他(合作组作者)
(3) From Mutation Signature to Molecular Mechanism in the RNA World: A Case of SARS-CoV-2, Genomics Proteomics Bioinformatics, 2020, 第 1 作者
(4) The Elements of Data Sharing, Genomics Proteomics Bioinformatics, 2020, 第 3 作者
(5) Genome Assembly and Pathway Analysis of Edible Mushroom Agrocybe cylindracea, Genomics Proteomics Bioinformatics, 2020, 第 7 作者
(6) A quasi-paired cohort strategy reveals the impaired detoxifying function of microbes in the gut of autistic children., Science Advances, 2020, 其他(合作组作者)
(7) CpG-Island-based annotation and analysis of human house-keeping genes, Briefings in Bioinformatics, 2020, 第 3 作者
(8) Meta-analysis Reveals Potential Influence of Oxidative Stress on the Airway Microbiomes of Cystic Fibrosis Patients, Genomics Proteomics Bioinformatics, 2020, 通讯作者
(9) Rice Genomics: over the Past Two Decades and into the Future, Genomics Proteomics Bioinformatics, 2019, 通讯作者
(10) Evolution of Complex Thallus Alga: Genome Sequencing of Saccharina japonica, Frontiers in Genetics, 2019, 通讯作者
(11) Microfluidics-Based Enrichment and Whole-Genome Amplification Enable Strain-Level Resolution for Airway Metagenomics., mSystems, 2019, 第 7 作者
(12) One thousand plant transcriptomes and phylogenomics of green plants, Nature, 2019, 其他(合作组作者)
(13) 实现“终极版”核苷酸测序仪的技术要素, 遗传, 2018, 第 1 作者
(14) RGAAT: A Reference-based Genome Assembly and Annotation Tool for New Genomes and Upgrade of Known Genomes, Genomics Proteomics Bioinformatics, 2018, 通讯作者
(15) Genome-wide definition of selective sweeps reveals molecular evidence of trait-driven domestication among elite goat (Capra species) breeds for the production of dairy, cashmere, and meat, GigaScience, 2018, 通讯作者
(16) The Bacterial RNA Ligase RtcB Accelerates the Repair Process of Fragmented rRNA upon Releasing the Antibiotic Stress, Science China-Life Sciences, 2018, 通讯作者
(17) On the core bacterial flora of Ixodes persulcatus, Plos One, 2017, 通讯作者
(18) Discovery of susceptibility loci associated with tuberculosis in Han Chinese, Hum Mol Genet, 2017, 第 10 作者
(19) MicroRNA Expression in Multistage Date Fruit Development, Methods Mol Biol, 2017, 第 3 作者
(20) identification of sequence variant associated with splicing event using RNA-seq data, BMC Bioinformatics, 2017, 通讯作者
(21) The rubber tree genome reveals new insights into rubber production and species adaptation, Nature Plants, 2016, 通讯作者
(22) MTD: a mammalian transcriptomic database to explore gene expression and regulation, Briefings in Bioinformatics, 2016, 通讯作者
(23) Complete Sequence and Analysis of Coconut Palm (Cocos nucifera) Mitochondrial Genome, PLOS ONE, 2016, 通讯作者
(24) Precision Medicine: What Challenges Are We Facing?, Genomics Proteomics & Bioinformatics, 2016, 通讯作者
(25) Plastid-LCGbase: a collection of evolutionarily conserved plastid-associated gene pairs, Nucleic Acids Research, 2015, 通讯作者
(26) KGCAK: a K-mer based database for genome-wide phylogeny and complexity evaluation, Biology Direct, 2015, 通讯作者
(27) LCGserver: A Webserver for Exploring Evolutionary Trajectory of Gene Orders in a Large Number of Genomes, OMICS, 2015, 通讯作者
(28) Profiling microRNA expression during multi-staged date palm (Phoenix dactylifera L.) fruit development, Genomics, 2015, 通讯作者
(29) A Transcriptomic Study of the Red Palm Weevil (Rhynchophorus ferrugineus) Embryogenesis, Insect Science, 2015, 通讯作者
(30) Heteroresistance at the single-cell level: adapting to antibiotic stress through a population-based strategy and growth-controlled interphenotypic coordination, mBio, 2014, 通讯作者
(31) Genome sequence and genetic diversity of the common carp, Cyprinus carpio, Nature Genetics, 2014, 通讯作者
(32) Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species, Genome Biology, 2014, 通讯作者
(33) The quest for a unified view of bacterial land colonization, The ISME Journal, 2014, 通讯作者
(34) Flexibility and Symmetry of Prokaryotic Genome Rearrangement Reveal Lineage-Associated Core-Gene-Defined Genome Organizational Frameworks, MBIO, 2014, 通讯作者
(35) The Rice Genome Knowledgebase (RGKbase): an annotation database for rice comparative genomics and evolutionary biology, Nucleic Acids Research, 2013, 通讯作者
(36) Genome sequence of the date palm Phoenix dactylifera L., NATURE COMMUNICATIONS, 2013, 通讯作者
(37) Functional networking of human divergently paired genes (DPGs), PLoS One, 2013, 通讯作者
(38) Improved picoliter-sized micro-reactors for high-throughput biological analysis, Sci China Life Sci., 2013, 通讯作者
(39) The intestinal metagenome of red palm weevil (Rhynchophorus ferrugineus), Environ Microbiol. , 2013, 通讯作者
(40) Systematic analysis of intron size parameters in diverse lineages, Sci China Life Sci., 2013, 通讯作者
(41) Expression profiling of abundant genes in pulmonary and cardiac muscle tissues of Tibetan Antelope (Pantholops hodgsonii), Gene, 2013, 通讯作者
(42) Mitochondrial genome sequences of Artemia tibetiana and A. urmiana: assessing molecular changes for high plateau adaptation, Sci China Life Sci., 2013, 通讯作者
(43) Identification of Human HK Genes and Gene Expression Regulation Study in Cancer from Transcriptomics Data Analysis, PLoS One, 2013, 通讯作者
(44) Complete genome sequence of methicillin-sensitive Staphylococcus aureus containing a heterogeneic staphylococcal cassette chromosome element, Sci China Life Sci., 2013, 通讯作者
(45) Transcriptome profiling of the developing postnatal mouse testis using next-generation sequencing, Sci China Life Sci., 2013, 通讯作者
(46) A Large-scale Gene Discovery for the Red Palm Weevil Rhynchophorus ferrugineus (Coleoptera: Curculionidae), Insect Sci., 2013, 通讯作者
(47) Replication-Associated Mutational Pressure (RMP) Governs Strand-Biased Compositional Asymmetry (SCA) and Gene Organization in Animal Mitochondrial Genomes, current genomics, 2012, 通讯作者
(48) A Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte, plos one, 2011, 通讯作者
(49) Nonsynonymous substitution rate (Ka) is a relatively consistent parameter for defining fastevolving and slow-evolving protein-coding genes, Biology Direct, 2011, 通讯作者
(50) On the Origin of Tibetans and Their Genetic Basis in Adapting High-Altitude Environments, plos one, 2011, 通讯作者
(51) Both Size and GC-Content of Minimal Introns Are Selected in Human Populations, plos one, 2011, 通讯作者
(52) Diverse LEA (late embryogenesis abundant) and LEA-like genes and their responses to hypersaline stress in post-diapause embryonic development of Artemia franciscana, Comparative Biochemistry and Physiology, Part B, 2011, 通讯作者
(53) Coevolution study of mitochondria respiratory chain proteins:Toward the understanding of proteineprotein interaction, Journal of Genetics and Genomics, 2011, 通讯作者
(54) The Disequilibrium of Nucleosomes Distribution along Chromosomes Plays a Functional and Evolutionarily Role in Regulating Gene Expression, plos one, 2011, 通讯作者
(55) An Integrated Analysis of miRNA and mRNA Expressions in Non-Small Cell Lung Cancers, plos one, 2011, 通讯作者
(56) An integrated analysis of lineage-specific small proteins across eight eukaryotes reveals functional and evolutionary significance, Progress in Biochemistry and Biophysics, 2011, 通讯作者
(57) Bar-Coded Pyrosequencing Reveals the Bacterial Community during Microcystis water Bloom in Guanting Reservoir,Beijing, Procedia Engineering, 2011, 通讯作者
(58) Comparative analysis of mitochondrial genomes between a wheat K-type cytoplasmic male sterility (CMS) line and its maintainer line, BMC genomics, 2011, 通讯作者
(59) An efficient procedure for plant organellar genome assembly, based on whole genome data from the 454 GS FLX sequencing platform, PLANT METHODS, 2011, 通讯作者
(60) Involvement of the GP63 protease in infection of Trichomonas vaginalis, Parasitol res, 2011, 通讯作者
(61) Transposable-Element Associated Small RNAs in Bombyx mori Genome, plos one, 2011, 通讯作者
发表著作
( 1 ) 基因组学核心实验方法, GENOMICS:ESSENTIAL METHODS, 科学出版社, 2012-03, 第 1 作者
( 2 ) 第二代测序信息处理, Next-Generation DNA Sequencing Informatics, 科学出版社, 2014-06, 第 3 作者
( 3 ) 基因组科学的甲子“羽化”之路——从人类基因组测序到精准医学, Mapping and Sequencing the Human Genome Toward Precision Medicine, 科学出版社, 2016-03, 第 1 作者
( 4 ) 基因组学与精准医学, Genomics and Precision Medicine, 上海交通大学, 2017-12, 第 1 作者
( 5 ) 遗传学:从基因到基因组(原书第六版), Genetics: From Genes to Genomes, 科学出版社, 2021-01, 第 1 作者

科研活动

   
科研项目
( 1 ) 小型猪和小鼠等医学实验哺乳动物模型建立与基础数据集成, 负责人, 国家任务, 2011-01--2015-08
( 2 ) 藏彝走廊世居群体遗传多样性调查, 参与, 国家任务, 2013-01--2016-12
( 3 ) 猪脂肪沉积等优质高产分子模块解析, 参与, 中国科学院计划, 2013-08--2017-12
( 4 ) 个体化医学检测的规范化、标准化研究及应用推广, 负责人, 国家任务, 2014-06--2016-12
( 5 ) 顽固群(persister)休眠细胞形成机制的单细胞水平研究, 负责人, 国家任务, 2015-01--2018-12
( 6 ) 基于焦磷酸微纳电化学传感器阵列的基因组测序系统, 负责人, 中国科学院计划, 2014-07--2016-06
( 7 ) 细菌中环状RNA的合成机制及其在对抗抗生素压力中的作用, 负责人, 国家任务, 2017-01--2020-12
( 8 ) 单分子操纵石墨烯纳米孔DNA测序仪, 负责人, 中国科学院计划, 2016-01--2017-12
( 9 ) 高速纳米孔核苷酸序列分析仪, 负责人, 中国科学院计划, 2016-01--2017-12
参与会议
(1)Cellular heterogeneity of cancers and resolutions of our technologies   2017-11-03
(2)Precision Medicine in China   2017“中国-东南亚国家联盟(Sino-ASEAN)”精准医学会议   2017-06-17
(3)Analysis of worldwide population structure of species Escherichia coil reveals two major subspecies   2017美国微生物学会年会   2017-06-01
(4)Lineage-associated Variations of Core Genomes Restrict Horizontal Gene Transfer and Species Divergence of Eubacterial Taxa   于军   2015-10-25
(5)Genome Structures of Major Lineages   2013国际基因组学大会   Jun Yu   2013-10-28
(6)Evolutionary Cell Biology: Minimal Intron-Containing(MIC) Genes and Beyond   国际基因组学大会   于军   2011-11-23
(7)Understanding Cellular Processes Based on DNA Variation Data   新一代测序亚洲大会   于军   2011-10-02