基本信息
李玉林  男  博导  中国科学院西北高原生物研究所
email: liyulin@nwipb.cas.cn
address: 西宁市城西区新宁路23号
postalCode: 810008

招生信息

   
招生专业
100800-中药学
招生方向
天然药物化学和药理药效
创新药物研发
藏药标准化

教育背景

2004-09--2007-07   中国科学院研究生院   理学博士
1988-09--1992-07   中山大学   理学学士

工作经历

   
工作简历
2013-06~现在, 中国科学院西北高原生物研究所, 研究员
2004-09~2007-07,中国科学院研究生院, 理学博士
2004-06~2013-05,中国科学院西北高原生物研究所, 副研究员
1997-11~2004-06,中国科学院西北高原生物研究所, 助理研究员
1992-07~1997-11,中国科学院西北高原生物研究所, 研究实习员
1988-09~1992-07,中山大学, 理学学士
社会兼职
2023-02-01-今,青海省政协, 常委
2022-10-01-今,中国民主同盟青海省委员会, 副主委
2020-09-01-今,中国土壤学会土壤分析技术工作委员会, 委员
2017-03-01-今,青海省西宁市科学技术协会, 常务委员会委员
2015-10-30-2019-06-30,中国民主同盟青海省委员会中科院支部, 主委

专利与奖励

   
奖励信息
(1) 中国科学院院所两级公共技术服务中心优秀个人, 部委级, 2020
(2) 青海省优秀专业技术人才, 省级, 2019
(3) 藏药安全与质量控制关键技术研究及应用, 一等奖, 部委级, 2017
(4) 中国科学院王宽城西部学者突出贡献奖, , 部委级, 2012
(5) 青藏高原青年科技奖, 一等奖, 专项, 2009
(6) 柴达木盆地白刺资源综合利用技术与产品研究开发及产业化, 二等奖, 国家级, 2007
(7) 中国科学院院长优秀奖, 二等奖, 部委级, 2007
(8) 柴达木盆地白刺资源综合利用技术与产品研究开发及产业化, 一等奖, 省级, 2006
(9) 沙棘总黄酮技术研究与高技术产品产业化, 二等奖, 省级, 2006
专利成果
( 1 ) 一种土壤元素分析仪的辅助进料装置及进料方法, 2021, 第 5 作者, 专利号: CN113156092A

( 2 ) 一种治疗慢性胆囊炎的藏茵陈总苦苷有效部位及其制备方法和应用, 2021, 第 1 作者, 专利号: CN112237585A

( 3 ) 不同种獐牙菜红外光谱鉴别方法, 2020, 第 6 作者, 专利号: CN111220562A

( 4 ) 一种川西獐牙菜产地的红外光谱鉴定方法, 2020, 第 5 作者, 专利号: CN111220561A

( 5 ) 一种快速检测黑果枸杞中花青素的方法, 2020, 第 2 作者, 专利号: CN110927088A

( 6 ) 一种快速检测青稞中直链淀粉和支链淀粉的方法, 2020, 第 2 作者, 专利号: CN110927152A

( 7 ) 可调换样位的全自动进样器、元素分析仪, 2019, 第 7 作者, 专利号: CN209280735U

( 8 ) 反应管清理器, 2019, 第 7 作者, 专利号: CN109433761A

( 9 ) 可调换样位的全自动进样器、元素分析仪, 2019, 第 7 作者, 专利号: CN109307781A

( 10 ) 一种从镰形棘豆中制备oxytroflavoside六种化合物的方法及其用途, 2018, 第 2 作者, 专利号: CN108659073A

( 11 ) 一种气相色谱在线固相萃取装置, 2018, 第 4 作者, 专利号: CN207263702U

( 12 ) 一种甘青青兰药材中三种化学对照品的制备方法, 2018, 第 2 作者, 专利号: CN107903176A

( 13 ) 一种治疗急慢性肝炎的藏茵陈有效部位及其制备方法和应用, 2018, 第 1 作者, 专利号: CN107875163A

( 14 ) 一种多通道可回收型中试亚临界流体萃取装置, 2018, 第 5 作者, 专利号: CN207076163U

( 15 ) 一种液化石油气萃取溶剂回收系统, 2018, 第 5 作者, 专利号: CN207024688U

( 16 ) 一种大黄药材中二苯乙烯类和苯丁酮类化学对照品的制备新方法, 2017, 第 2 作者, 专利号: CN107474083A

( 17 ) 一种藏茵陈药材中三种苷类化学对照品的制备新方法, 2017, 第 1 作者, 专利号: CN107446005A

( 18 ) 一种川西獐牙菜生态抚育方法, 2017, 第 4 作者, 专利号: CN107278605A

( 19 ) 一种从镰形棘豆中分离制备5种具有抗炎活性化合物的方法, 2017, 第 2 作者, 专利号: CN106905278A

( 20 ) 一种从镰形棘豆中具有抗炎活性总黄酮的提取方法, 2017, 第 2 作者, 专利号: CN106727881A

( 21 ) 一种循环通用型高速逆流色谱仪, 2017, 第 2 作者, 专利号: CN206038625U

( 22 ) 一种高速逆流色谱仪循环进样装置, 2017, 第 2 作者, 专利号: CN206038627U

( 23 ) 一种新的甾体类化合物及其制备方法和应用、药物组合物及其应用, 2017, 第 1 作者, 专利号: CN106432391A

( 24 ) 一种新的半日花烷型二萜化合物及其制备方法和应用、药物组合物及其应用, 2017, 第 2 作者, 专利号: CN106397369A

( 25 ) 基于平行分离模式制备色谱分离棘豆中化学对照品的方法, 2017, 第 3 作者, 专利号: CN106366140A

( 26 ) 一种新的倍半萜化合物及其生物医药用途, 2016, 第 2 作者, 专利号: CN106243065A

( 27 ) 大黄中蒽醌苷类物质的分离方法, 2016, 第 2 作者, 专利号: CN106117282A

( 28 ) 诃子药材中诃子酸、诃黎勒酸和鞣花酸三种化学对照品的制备方法, 2016, 第 1 作者, 专利号: CN105949252A

( 29 ) 一种从镰形棘豆中分离制备5种黄酮类化合物的方法, 2016, 第 2 作者, 专利号: CN105884736A

( 30 ) 一种黄酮类药物组合物及制备方法和用途, 2016, 第 2 作者, 专利号: CN105796548A

( 31 ) 一种新的羊毛甾烷型三萜化合物及其制备方法和医药用途, 2016, 第 1 作者, 专利号: CN105524134A

( 32 ) 基于平行分离模式制备色谱分离棘豆中新化合物方法, 2016, 第 2 作者, 专利号: CN105481921A

( 33 ) 一种具有平行分离模式的制备色谱装置, 2016, 第 3 作者, 专利号: CN205049535U

( 34 ) 一种用于快速富集浓缩中藏药馏分的装置, 2016, 第 3 作者, 专利号: CN205049534U

( 35 ) 青海柴达木枸杞多糖提取分离制备新方法, 2014, 第 2 作者, 专利号: CN104059163A

( 36 ) 一种从藏茵陈中分离制备四种苷类化学对照品的方法, 2013, 第 2 作者, 专利号: CN103408602A

( 37 ) 大黄药材中蒽醌苷和二苯乙烯苷化学对照品的制备方法, 2013, 第 3 作者, 专利号: CN103408613A

( 38 ) 藏茵陈药材中獐牙菜醇苷化学对照品的制备方法, 2013, 第 3 作者, 专利号: CN103408615A

( 39 ) 一种DPPH-HPLC法检测白刺果汁中抗氧化成分的方法, 2013, 第 2 作者, 专利号: CN102879499A

( 40 ) 一种DPPH-HPLC法检测黑果枸杞果汁中抗氧化成分的方法, 2013, 第 4 作者, 专利号: CN102879500A

( 41 ) 一种山莨菪根中东莨菪苷单体的制备方法, 2012, 第 3 作者, 专利号: CN102617674A

( 42 ) 藏茵陈有效部位提取物的制备方法, 2012, 第 1 作者, 专利号: CN102579564A

( 43 ) 黑果枸杞原花青素产品及其制备方法, 2011, 第 6 作者, 专利号: CN101982192A

( 44 ) 一种从白刺果汁中分离纯化色氨酸单体的制备方法, 2011, 第 7 作者, 专利号: CN101948420A

( 45 ) 青稞黄酮提取物的制备新工艺及其在保健酒中的应用, 2010, 第 1 作者, 专利号: CN101696381A

( 46 ) 青稞黄酮高含量提取物的制备方法及其在保健品中的应用, 2009, 第 1 作者, 专利号: CN101361932A

( 47 ) 改善睡眠保健药物组合物的制备工艺, 2007, 第 4 作者, 专利号: CN1293914C

( 48 ) 白刺籽油的超临界CO 2 萃取工艺及其在降血脂中的应用, 2005, 第 2 作者, 专利号: CN1687340

( 49 ) 从沙生植物白刺中提取食用天然红色素的工艺, 2005, 第 3 作者, 专利号: CN1687238A

( 50 ) 综合利用低次烟叶中烟碱及其副产品芦丁的制备新工艺, 1998, 第 2 作者, 专利号: CN1201034A

出版信息

   
发表论文
(1) 异叶青兰生药学研究, Study on Pharmacognosy of Dracocephalum heterophyllum Benth., 中医药学报, 2022, 第 7 作者
(2) HSCCC Separation of Three Main Compounds from the Crude Extract of Dracocephalum Tanguticum by Using Dimethyl Sulfoxide as Cosolvent, JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2021, 第 7 作者
(3) 藏药诃子质量标志物诃子酸的分离分析及标准化研究, Separation and Standardization of Chebulinic Acid as Quality Marker of Tibetan Medicine Terminalia Chebula, 分析测试技术与仪器, 2021, 第 10 作者
(4) Current strategies for the development of fluorescence-based molecular probes for visualizing the enzymes and proteins associated with Alzheimer’s disease, COORDINATION CHEMISTRY REVIEWS, 2021, 第 7 作者
(5) 电感耦合等离子体发射光谱法测定饲料中8种元素含量的不确定度分析, Uncertainty analysis of measurement of eight elements in feed by inductively coupled plasma emission spectrometry, 饲料研究, 2021, 第 6 作者
(6) 青藏高原黑果枸杞花青素对人肝癌细胞增殖和自噬的影响, Effect of anthocyanidin of Lycium ruthenicum Murry from Qinghai Tibet Plateaun on the proliferation and autophagy of HepG2 cells, 天然产物研究与开发, 2021, 第 2 作者
(7) Separation of five flavonoids with similar polarity from Caragana korshinskii Kom. by preparative high speed counter-current chromatography with recycling and heart cut mode, JOURNAL OF SEPARATION SCIENCE, 2020, 通讯作者
(8) 响应面法优化柠条锦鸡儿花中总黄酮超声提取工艺, 天然产物研究与开发, 2020, 通讯作者
(9) Theoretical Insights into Ester-Directed Reactions between Propiolates with 1,2-Benzisoxazoles by Au(I) Catalyst: 4+2-Annulation versus Michael-Type Products, ORGANOMETALLICS, 2020, 第 6 作者
(10) Mechanistic insights into the origin of substituent-directed product Z–E selectivity for gold-catalyzed 4+1-annulations of 1,4-diyn-3-ols with isoxazoles: A DFT study, MOLECULAR CATALYSIS, 2020, 第 5 作者
(11) 石墨炉原子吸收光谱法测定饲料中铅含量不同前处理方法的评价, Evaluation of different pretreatment methods for determination of lead content in feed by graphite furnace atomic absorption spectrometry, 饲料研究, 2020, 第 4 作者
(12) Efficient Separation of Five Flavonoids from Oxytropis falcata Bunge by High-Speed Counter-Current Chromatography and their Anticancer Activity, ACTA CHROMATOGRAPHICA, 2020, 第 5 作者
(13) 藏药材诃子中3种α-葡萄糖苷酶抑制剂的分离与鉴定, Isolation and identification of threeα-glucosidase inhibitors from Terminalia chebula Retz., 天然产物研究与开发, 2020, 第 5 作者
(14) 顶空固相微萃取-气质联用技术分析青海省不同产地牦牛肉中挥发性风味成分, Analysis of Volatile Flavor Components in Yak Meat from Different Producing Areas of Qinghai Province by Head⁃Space Solid⁃Phase Microextraction and Gas Chromatography⁃Mass Spectrometry Technique, 动物营养学报, 2020, 第 2 作者
(15) Theoretical elucidation of the multi-functional synthetic methodology for switchable Ni(0)-catalyzed C-H allylations, alkenylations and dienylations with allenes, CATALYSIS SCIENCE & TECHNOLOGY, 2020, 第 5 作者
(16) A bright two-photon fluorescence probe with large stokes shift for deep tissue imaging of H2S during metabolism, DYES AND PIGMENTS, 2020, 第 9 作者
(17) 青海省不同生态区野生金露梅叶生物活性成分分析和评价, Analysis and Assessment of Bioactive Components of Potentilla fruticosa Leaves in Different Ecological Areas of Qinghai Province, 食品工业科技, 2019, 第 6 作者
(18) 便携式食品直链和支链淀粉速测仪的研制, Development of Portable Speed Measuring Apparatus for Amylose and Amylopectin in Food, 分析测试技术与仪器, 2019, 第 6 作者
(19) Combined chromatographic strategy based on macroporous resin, high-speed counter-current chromatography and preparative HPLC for systematic separation of seven antioxidants from the fruit of Terminalia billerica, JOURNAL OF SEPARATION SCIENCE, 2019, 通讯作者
(20) 藏药安全与质量控制关键技术研究及应用, 青海科技, 2019, 第11作者
(21) An effective method based on medium-pressure liquid chromatography and recycling high-speed counter-current chromatography for enrichment and separation of three minor components with similar polarity from Dracocephalum tanguticum, JOURNAL OF SEPARATION SCIENCE, 2019, 通讯作者
(22) Ratiometric two-photon fluorescent probe for in situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication, CHEMICAL COMMUNICATIONS, 2019, 第 8 作者
(23) A practicable strategy for enrichment and separation of four minor flavonoids including two isomers from barley seedlings by macroporous resin column chromatography, medium-pressure LC, and high-speed countercurrent chromatography, JOURNALOFSEPARATIONSCIENCE, 2019, 通讯作者
(24) 多通道可回收型中试亚临界流体萃取装置的改造及功能拓展, Modification and Development of Multichannel Recyclable Pilot Sub-Critical Fluid Extraction Device, 分析测试技术与仪器, 2019, 第 6 作者
(25) Separation of three polar compounds from Rheum tanguticum by high-speed countercurrent chromatography with an ethyl acetate/glacial acetic acid/water system, JOURNAL OF SEPARATION SCIENCE, 2018, 通讯作者
(26) 基于全二维气相色谱在线SPE技术分析沉香精油挥发性香气成分, Analysis of Components in Agarwood Essential Oil by On-Line Solid Phase Extraction with Comprehensive Two-Dimensional Gas Chromatography-Mass Spectrometry, 植物学研究, 2018, 第 8 作者
(27) Rationally Optimized Fluorescent Probe for Imaging Mitochondrial SO2 in HeLa Cells and Zebrafish, ANALYTICAL CHEMISTRY, 2018, 第 6 作者
(28) Separation of six compounds including two n-butyrophenone isomers and two stibene isomers from Rheum tanguticum Maxim by recycling high speed counter-current chromatography and preparative HPLC, Journal of Separation Science, 2018, 通讯作者
(29) Separation of six xanthones from Swertia franchetiana by high-speed countercurrent chromatography, JOURNAL OF SEPARATION SCIENCE, 2017, 通讯作者
(30) 微波消解/ICP-MS法测定镰形棘豆中18种元素含量, Determination of Content of Elements of Oxytropis falcata Bunge by ICP-MS After Microwave-Assisted Digestion, 分析测试技术与仪器, 2017, 第 4 作者
(31) Large-Scale Preparation of a Specific Xanthone from Swertia mussotii and Evaluation of Its alpha-Glucosidase Inhibitory Activity, JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2017, 通讯作者
(32) Bright and sensitive ratiometric fluorescent probe enabling endogenous FA imaging and mechanistic exploration of indirect oxidative damage due to FA in various living systems, CHEMICAL SCIENCE, 2017, 第 8 作者
(33) Large-Scale Preparation of a Specific Xanthone from Swertia mussotii and Evaluation of Its α-Glucosidase Inhibitory Activity, JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2017, 第 5 作者
(34) 亚临界流体1,1,1,2-四氟乙烷(R134a)萃取黑果枸杞原花青素的工艺研究及不同产地含量测定, The Technical Research of Extraction of Procyanidins in Lycium ruthenicum Murr. Using Sub-Critical Fluid 1,1,1,2-Tetrafluoroethane (R134a) and the Contents Determination from Different Origins, 植物学研究, 2017, 第 7 作者
(35) Isolation and Purification of Three Analogues from Clematis akebioides by Molecularly Imprinted Solid-Phase Extraction and HSCCC, CHROMATOGRAPHIA, 2017, 通讯作者
(36) Separation of 4 '-demethyldeoxypodophyllotoxin from Sinopodophyllum emodi by medium-pressure LC and high-speed counter-current chromatography guided by HPLC-MS, SEPARATION SCIENCE AND TECHNOLOGY, 2017, 通讯作者
(37) First separation of four aromatic acids and two analogues with similar structures and polarities from Clematis akebioides by high-speed counter-current chromatography, JOURNAL OF SEPARATION SCIENCE, 2016, 通讯作者
(38) Separation of three anthraquinone glycosides including two isomers by preparative HPLC and HSCCC from Rheum tanguticum Maxim, journal of separation science, 2016, 通讯作者
(39) An Efficient Protocol for Preparation of Gallic Acid from Terminalia bellirica (Gaertn.) Roxb by Combination of Macroporous Resin and Preparative High-Performance Liquid Chromatography, JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2016, 通讯作者
(40) Separation of three anthraquinone glycosides including two isomers by preparative high-performance liquid chromatography and high-speed countercurrent chromatography from Rheum tanguticum Maxim. ex Balf, JOURNAL OF SEPARATION SCIENCE, 2016, 通讯作者
(41) Separation of Three Phenolic Compounds with High-Molecular Weight from the Crude Extract of Terminalia Chebula Retz. by Ultrasonic-assisted Extraction and High-Speed Counter-Current Chromatography, Journal of Separation Science, 2016, 通讯作者
(42) An Efficient Protocol for Large-scale Preparation of Gallic Acid from Terminalia Billerica (Gaertn.) Roxb by Combination of Macroporous Resin and Preparative High-performance Liquid Chromatography, Journal of Chromatographic Science, 2016, 通讯作者
(43) Separation of three phenolic high-molecular-weight compounds from the crude extract of Terminalia Chebula Retz. by ultrasound-assisted extraction and high-speed counter-current chromatography, JOURNAL OF SEPARATION SCIENCE, 2016, 通讯作者
(44) Rapid Screening, Identification, Separation, and Purification of Four Bioactive Compounds from Swertia mussotii Franch, SEPARATION SCIENCE AND TECHNOLOGY, 2015, 通讯作者
(45) Trace Elements in Lycium barbarum L. Leaves by Inductively Coupled Plasma Mass Spectrometry after Microwave Assisted Digestion and Multivariate Analysis, SPECTROSCOPY LETTERS, 2015, 通讯作者
(46) Application of an efficient strategy based on liquid-liquid extraction, HSCCC and preparative HPLC for rapid enrichment, separation and purification of four anthraquinones from Rheum tanguticum, Journal of Separation Science, 2014, 通讯作者
(47) Xanthones from Swertia mussotii as Multitarget-Directed Antidiabetic Agents, CHEMMEDCHEM, 2014, 第 7 作者
(48) Application of high-speed counter-current chromatography combined with macroporous resin for rapid enrichment and separation of three anthraquinone glycosides and one stilbene glycoside from Rheum tanguticum, JOURNAL OF CHROMATOGRAPHY B, 2014, 第 7 作者
(49) 半制备型高速逆流色谱分离制备铁棒锤根中的一种咪唑生物碱, Isolation and preparation of an imidazole alkaloid from radix of Aconitum pendulum Busch by semi-preparative high-speed counter-current chromatography, 色谱, 2014, 第 5 作者
(50) Application of high-speed counter-current chromatography combined with macroporous resin for rapid enrichment and separation of three anthraquinone glycosides and one stilbene glycoside from Rheum tanguticum, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2014, 第 7 作者
(51) One-Step Isolation and Purification of Four Xanthone Glycosides from Tibetan Medicinal Plant Halenia elliptica by High-Speed Counter-Current Chromatography, SEPARATION SCIENCE AND TECHNOLOGY, 2014, 通讯作者
(52) Separation of Phenylpropanoid Glycosides from a Chinese Herb by HSCCC, JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2014, 第 4 作者
(53) 响应面法优化铁棒锤根中一种咪唑生物碱的超声提取工艺, 天然产物研究与开发, 2014, 第 5 作者
(54) One-step high-speed counter-current chromatography preparative isolation and purification of four xanthone glycosides from Tibetan medicinal plant Halenia elliptica, Separation Science and Technology, 2014, 通讯作者
(55) Application of an efficient strategy based on liquid-liquid extraction, high-speed counter-current chromatography, and preparative HPLC for the rapid enrichment, separation, and purification of four anthraquinones from Rheum tanguticum, JOURNAL OF SEPARATION SCIENCE, 2014, 通讯作者
(56) A Density Functional Theory Study on the Catalytic Mechanism of Hydroxycinnamoyl-CoA Hydratase-Lyase, INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, 2014, 第 2 作者
(57) Preparation of two flavonoid glycosides with unique structures from barley seedlings by membrane separation technology and preparative high-performance liquid chromatography, JOURNAL OF SEPARATION SCIENCE, 2014, 通讯作者
(58) One-step Separation and Purification of Three Lignans and One Flavone from Sinopodophyllum Emodi by Medium-pressure Liquid Chromatography and High-speed Counter-current Chromatography, Phytochemical Analysis, 2013, 通讯作者
(59) Preparative Isolation and Purification of Three Stilbene Glycosides from the Tibetan Medicinal Plant Rheum tanguticum Maxim. Ex Balf. by High-speed Counter-current Chromatography, PHYTOCHEMICAL ANALYSIS, 2013, 第 3 作者
(60) SEMI-PREPARATIVE SEPARATION AND PURIFICATION OF THREE FLAVONOIDS FROM PEDICULARIS LONGIFLORA VAR. TUBIFORMIS (KLOTZSCH) P. C. TSOONG BY HSCCC, JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2013, 第 3 作者
(61) Antioxidant xanthones from Swertia mussotii, a high altitude plant, FITOTERAPIA, 2013, 第 7 作者
(62) One-step Separation and Purification of Three Lignans and One Flavonol from Sinopodophyllum emodi by Medium-pressure Liquid Chromatography and High-speed Counter-current Chromatography, PHYTOCHEMICAL ANALYSIS, 2013, 通讯作者
(63) 唐古特大黄中大黄酚苷超声提取工艺的响应面优化及HPLC测定, Optimization of ultrasound-assisted extraction with RSM and HPLC determination for chrysophanol glycosides in rheum tanguticum, 分析试验室, 2012, 第 2 作者
(64) Preparative separation of methylswertianin, swerchirin and decussatin from the Tibet medicinal plant Swertia mussotii by high-speed counter-current chromatography, Phytochemical Analysis, 2012, 通讯作者
(65) 高速逆流色谱分离制备川西獐牙菜中两种苷类化合物, Preparative Separation of Two glycosides from Swertia Mussotti by High-Speed Counter-Current Chromatography, 天然产物研究与开发, 2012, 第 5 作者
(66) 微波消解/ICP-MS法测定不同地点三种马先蒿16种元素, 光谱学与光谱分析, 2012, 第 2 作者
(67) 响应面法优化桃儿七中鬼臼毒素的热回流提取工艺, 中药材, 2012, 通讯作者
(68) PREPARATIVE ISOLATION AND PURIFICATION OF LUTONARIN AND SAPONARIN FROM BARLEY SEEDLINGS BY HSCCC, JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2012, 通讯作者
(69) 微波消解/ICP-MS法测定不同地点三种马先蒿16种元素, Determining of the Content of Determination of Elements of Pedicularis from Different Places by ICP-MS after Micriware-Assisted Digestion, 光谱学与光谱分析, 2012, 第 2 作者
(70) 高效液相色谱-电喷雾/质谱法测定青稞幼苗提取物氨基酸, Determination of Amino Acids from Highland Barley Seedlings Extract by HPLC-ESI/MS, 光谱实验室, 2012, 第 5 作者
(71) Preparative Isolation and Purification of Lutonarin and Saponarin from Barley Seedling by HSCCC, Journal of Liquid Chromatography and Related Technologies, 2012, 通讯作者
(72) 高速逆流色谱分离制备椭圆叶花锚中的2种口山酮苷元, Preparative separation of two xanthones from Halenia elliptica by high-speed counter-current chromatography, 色谱, 2012, 第 6 作者
(73) LC Determination of Trace Biogenic Amines in Foods Samples, CHROMATOGRAPHIA, 2011, 第 8 作者
(74) 高速逆流色谱分离纯化川西獐牙菜中3种山酮苷元, 分析化学, 2011, 第 2 作者
(75) 高速逆流色谱分离纯化川西獐牙菜中三种口山酮苷元, 分析化学, 2011, 通讯作者
(76) LC Determination of Trace Biogenic Amines in Foods Samples with Fluorescence Detection and MS Identification, CHROMATOGRAPHIA, 2011, 第 8 作者
(77) 青稞生长期间叶片中大麦黄苷和皂草黄苷的积累及品种间差异, 食品科学, 2010, 通讯作者
(78) 青稞生长期间叶片中大麦黄苷与皂草黄苷的积累及品种间差异, Accumulation of Lutonarin and Saponarin in Barley Leaves during Growth and Differences in Their Contents among Different Varieties, 食品科学, 2010, 第 2 作者
(79) 2一(苯并吖啶酮)一乙基咪唑酸酯探针对荧光和质谱的双增敏作用, 分析化学, 2010, 第 7 作者
(80) 新型荧光试剂用于土壤中脂肪胺的高效液相色谱-质谱测定, Determination of Aliphatic Amines in Soil Using Novel Pre-Column Derivatization Reagent with High Performance Liquid Chromatography Atmospheric Pressure Chemical Ionization-Mass Spectrometry Identification, 分析科学学报, 2010, 第 6 作者
(81) Dual-sensitive Probe 2-(12-Oxobenzobacridin-5(12H)-yl)ethyl 4-Toluenesulfonate for Bile Acids: Fluorescence Detection and APCI-MS Identification, ACTA CHIMICA SINICA, 2010, 第 9 作者
(82) 黄金蝉若虫体蛋白水解液的荧光标记及电喷雾质谱鉴定, Application of 2-2-(7H-Dibenzoa,g-carbazol-7-yl)-ethoxylethyl Chloroformate as A Pre-column Derivatization Reagent for Determination of Amino Acids from Hydrolyzed Cicada by High Performance Liquid Chromatography with Fluorescence Detection and Mass S, 分析化学, 2010, 第 7 作者
(83) 藏药川西獐牙菜活性成分的超声提取工艺研究, Research on Ultrasonic Wave Extraction of Active Components in Swertia mussotii, 天然产物研究与开发, 2010, 第 5 作者
(84) 柱前衍生化-非水毛细管电泳法高效分离饮料中的脂肪醛, Separation of derivatized aliphatic aldehydes in beverage by nonaqueous capillary electrophoresis, 色谱, 2010, 第 7 作者
(85) An improved reagent for determination of aliphatic amines with fluorescence and online atmospheric chemical ionization-mass spectrometry identification, ANALYTICA CHIMICA ACTA, 2010, 第 5 作者
(86) 青稞黄酮体外清除自由基活性研究, Study on Free Radical Scavenging Effects of Barley Flavonoids, 天然产物研究与开发, 2010, 第 2 作者
(87) 胆汁酸的双敏感探针苯并b吖啶酮-5-乙基对甲苯磺酸酯荧光检测和APCI-MS 鉴定, 化学学报, 2010, 第 9 作者
(88) Dual-Sensitive Probe of 2-(Benzoacridin)ethyl-imidazole-1-carboxylate for Determination of Aliphatic Amine with Fluorescence and Online Atmospheric Pressure Chemical Ionization Mass Spectrometry Identification, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2010, 第 7 作者
(89) Application of 2-2-(7H-Dibenzoa,g-carbazol-7-yl)-ethoxyl ethyl Chloroformate as A Pre-column Derivatization Reagent for Determination of Amino Acids from Hydrolyzed Cicada by High Performance Liquid Chromatography with Fluorescence Detection and Mass Spectrometric Identification, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2010, 第 7 作者
(90) Syntheses of Fluorescence Probe 5-2-(1H-imlidazol-1-yl)-2-oxoethyl benzobacridin-12(5H)-one and Its Application for the Determination of Aliphatic Amines with LC-APCI-MS, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2009, 第 6 作者
(91) 正交试验法优化青稞叶黄酮的提取工艺, Orthogonal Test for Optimizing the Extracting Method of Flavonoids from Barley Leaves, 天然产物研究与开发, 2009, 
(92) A sensitive fluorescence reagent for the determination of aldehydes from alcoholic beverage using high-performance liquid chromatography with fluorescence detection and mass spectrometric identification, ANALYTICA CHIMICA ACTA, 2009, 第 7 作者
(93) Determination of Free Aliphatic Amines in Environmental Water by EASC Derivatization and Identification with LC-APCI-MS, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2009, 第 8 作者
(94) Application of 10-ethyl-acridine-3-sulfonyl chloride for HPLC determination of aliphatic amines in environmental water using fluorescence and APCI-MS, JOURNAL OF SEPARATION SCIENCE, 2009, 第 7 作者
(95) 复合白刺籽油软胶囊免疫调节作用研究, 中成药, 2008, 第 3 作者
(96) Separation and determination of flavone and xanthone glycosides in Tibetan folk medicinal species Swertia mussotii and S-franchetiana by capillary electrophoresis, JOURNAL OF ANALYTICAL CHEMISTRY, 2008, 
(97) 青海栽培和野生唐古特大黄蒽醌类成分的HPLC对比分析, Comparative Analysis of Anthraquinones Content Between Cultivated and Wild Rheum tanguticum, 天然产物研究与开发, 2008, 第 1 作者
(98) CE determination of 2-(9-carbazole)ethyl chloroformate-labeled oligopeptides, CHROMATOGRAPHIA, 2008, 第 5 作者
(99) 柱前衍生-高效液相色谱分离测定及质谱鉴定脂肪胺, 分析化学, 2007, 第 2 作者
(100) Mass spectrometric identification of multihydroxy phenolic compounds in Tibetan herbal medicines, CHROMATOGRAPHIA, 2007, 第 5 作者
(101) Determination of free fatty acids in soil and bryophyte plants by precolumn derivatization via HPLC with fluorescence detection and tandem mass spectrometry (HPLC-MS/MS), JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2007, 第 5 作者
(102) Extraction of Nitraria tangutorum seed oil by supercritical carbon dioxide and determination of free fatty acids by HPLC/APC/IMS with fluorescence detection, SEPARATION AND PURIFICATION TECHNOLOGY, 2007, 第 4 作者
(103) Separation and determination of the major active components in Tibetan folk medicinal species Swertia franchetiana by HPLC with DAD, JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2007, 第 1 作者
(104) Chemical Constituents of Nitraira tangutorum Seed from Qaidam Basin, WANGHONGLUNLIYULINWANGXIAOYANSUOYOURUICHEMICALCONSTITUENTSOFNITRAIRATANGUTORUMSEEDFROMQAIDAMBASIN天然产物研究与开发2007194614616, 2007, 第 2 作者
(105) 复合白刺籽油软胶囊抗疲劳作用研究, 中成药, 2007, 第 3 作者
(106) Determination of long-chain fatty acids in bryophyte plants extracts by HPLC with fluorescence detection and identification with MS, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 第 4 作者
(107) Comparative analysis of allantoin quercetin, and 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid in Nitraria tangutorum Bobr. Seed by HPLC-APCI-MS and CE, JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2007, 第 6 作者
(108) “藏茵陈”类植物化学成分的结构鉴定及高效液相色谱/质谱分析表征, 2007, 第 1 作者
(109) HPLC-APCI-MS法分析测定白刺籽油中游离脂肪酸, Determination of free fatty acids in nitraria seed oil by HPLC-APCI-MS, 分析试验室, 2007, 第 5 作者
(110) 白刺与枸杞中微量元素含量的对比研究, Compare Analysis on The Content of Trace Elements in Nitraria tangutorun Bobr. and Licum bararum L., 广东微量元素科学, 2007, 第 3 作者
(111) Study of a new derivatizing reagent that improves the analysis of amino acids by HPLC with fluorescence detection: application to hydrolyzed rape bee pollen, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2007, 第 7 作者
(112) 液相色谱/质谱大气压化学电离源鉴定深海鱼油中长链不饱和脂肪酸, Identification of Long-chain Unsaturated Fatty Acids in Deep-sea Fish Oil by Liquid Chromatography/Mass Spectrometry/Atmospheric Proessure Chemical Ionization, 分析化学, 2007, 第 5 作者
(113) Pre-column derivatization-high performance liquid chromatography for the determination of aliphatic amines with fluorescence detection and mass spectrometric identification, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2007, 第 2 作者
(114) 栽培唐古特大黄蒽醌含量的季节动态变化, 西北植物学报, 2006, 第 2 作者
(115) 人工栽培唐古特大黄中蒽醌含量水平的分析, 天然产物研究与开发, 2006, 第 1 作者
(116) 藏药麻花艽中四种苦苷类化学成分的HPLC测定, Determination of four iridoid glycosides in tibetan medicine Gentiana straminea Maxim. by HPLC, 分析试验室, 2006, 第 3 作者
(117) 柴达木盆地唐古特白刺籽油的抗疲劳作用, The Anti-Fatigue Effect of Nitraria tangutorum Bobr.Seed Oil from Qaidam Basin on the Mice, 天然产物研究与开发, 2006, 第 3 作者
(118) 青海地区唐古特大黄药材HPLC指纹图谱研究, 中草药, 2006, 第 5 作者
(119) 高效液相色谱荧光测定及质谱鉴定土壤和苔藓中的脂肪酸, Determination of Free Fatty Acids from Soil and Bryophyte by High Performance Liquid Chromatography with Fluorescence Detection and Their Mass Spectrum Identification, 分析化学, 2006, 第 2 作者
(120) 毛细管电泳法分析唐古特白刺种子中两种生物碱, Determination of two alkaloids in Nitraria tangutorum Bobr. seed by capillary electrophoresis, 分析试验室, 2006, 第 3 作者
(121) 正交实验研究白刺种子尿囊素提取工艺, 天然产物研究与开发, 2006, 第 2 作者
(122) 辐状肋柱花的苷类成分, Glycosides of Lomatogonium rotatum, 西北植物学报, 2006, 第 1 作者
(123) HPLC法测定野生与栽培藏药麻花艽中4种环烯醚萜苷类成分的含量, 药物分析杂志, 2006, 第 3 作者
(124) 不同生长季节下藏药麻花秦艽活性成分含量研究, 云南植物研究, 2006, 第 2 作者
(125) 栽培藏药材麻花艽中四种苦苷类成分含量的季节性变化, 天然产物研究与开发, 2006, 第 3 作者
(126) 柴达木盆地唐古特白刺果实调节免疫、抗疲劳和耐寒冷作用研究, Effect of Fruit of Nitraria tangutorum Bobr. from Qaidam Basin on Immunomodulatory, Anti-fatigue and Cold-tolerance, 天然产物研究与开发, 2005, 第 2 作者
(127) 珠芽蓼全草化学成分研究, 天然产物研究与开发, 2005, 第 2 作者
(128) 珠芽蓼果实化学成分研究, 西北植物学报, 2005, 第 2 作者
(129) 高效液相色谱/质谱分析抱茎獐牙菜提取物中的苷性成分, Analysis of Five Glycosides in Swertin Franchetiana H. Smith Extracts by High Performance Liquid Chromatography and Atmospheric Pressure Chemical Ionization-Mass Spectrometry, 分析化学, 2005, 第 4 作者
(130) 藏药大果大戟中的巨大戟烷型二萜酯类成分, Ingenane diterpene ester constituents from Tibetan medicine Euphorbia wallichii, 中草药, 2005, 第 1 作者
(131) 红景天中红景天甙和酪醇的毛细管电泳法分析, 分析试验室, 2005, 第 3 作者
(132) 传统藏药材波棱瓜的氨基酸分析, Analysis of Amino Acids in Tibetan Medicine Herpetospermum penduculosum, 氨基酸和生物资源, 2005, 第 1 作者
(133) 白刺种子黄酮类化合物最佳提取工艺研究, 食品科学, 2004, 第 2 作者
(134) 尖苞雪莲的化学成分, 西北植物学报, 2004, 第 1 作者
(135) 传统藏药材波棱瓜的微量元素分析, 广东微量元素科学, 2003, 第 4 作者
(136) 藏药安神丸的超临界提取工艺, Preparation process for Tibetan Anshen Pills with supercritical fluid extraction, 中成药, 2002, 第 2 作者
(137) 棘豆属植物化学成分研究概况, A SURVEY OF THE STUDIES ON CHEMICAL CONSTITUENTS OF OXYTROPIS SPECIES, 天然产物研究与开发, 2002, 第 1 作者
(138) 红直獐牙菜的苷类成分, 中草药, 2002, 第 1 作者
(139) 薄层扫描法测定小檗属三种植物中的小檗碱含量, 1999, 第 2 作者
(140) 青海产三颗针中盐酸小檗碱的最佳提取工艺研究, 天然产物研究与开发, 1998, 第 2 作者
(141) 急弯棘豆化学成分的研究, 中草药, 1998, 第 1 作者
(142) Separation of Four Phenylpropanoid Glycosides from a Chinese Herb by HSCCC, JOURNAL OF CHROMATOGRAPHIC SCIENCE, 

科研活动

   
科研项目
( 1 ) 基于HPLC/MS分析技术化学筛选藏茵陈的抗HBV活性部位, 负责人, 国家任务, 2009-01--2011-12
( 2 ) 柴达木盆地枸杞活性成分多糖和色素提取分离技术及中试生产工艺研究, 负责人, 地方任务, 2010-01--2011-12
( 3 ) 高原生物的分子适应机制与资源持续利用, 参与, 国家任务, 2011-01--2013-12
( 4 ) 西北区域大黄、青海冬虫夏草、荒漠肉苁蓉、新疆马鹿等大宗中药材规范化种植/养殖基地及其SOP优化升级研, 参与, 国家任务, 2011-01--2014-12
( 5 ) 藏茵陈特征活性成分的高效分离制备及标准化研究, 负责人, 地方任务, 2012-07--2014-12
( 6 ) 藏药材活性成分标准化及质量控制技术研究, 负责人, 地方任务, 2015-07--2018-12
( 7 ) 藏茵陈片质量控制标准和生产工艺技术改进及产业化, 参与, 地方任务, 2014-01--2016-12
( 8 ) 青稞特色食品生产技术熟化及产业化, 参与, 地方任务, 2014-01--2016-12
( 9 ) 基于藏茵陈资源治疗黄疸型肝炎四类中药新药的研发, 负责人, 中国科学院计划, 2016-01--2017-12
( 10 ) 青藏高原特色生物资源工程研究中心能力建设, 负责人, 地方任务, 2017-01--2019-12
( 11 ) 藏茵陈肝胆宁新药的临床前研究, 负责人, 国家任务, 2017-01--2020-12
( 12 ) 藏茵陈二次开发-藏茵陈I类创新药的临床前研究, 负责人, 地方任务, 2019-01--2021-12
( 13 ) 青海省藏药国家标准样品研制科技基础条件平台建设项目, 负责人, 地方任务, 2020-01--2022-12
( 14 ) 基于UPLC的高原药用植物降血压活性成分快速筛选系统的建立, 负责人, 中国科学院计划, 2022-01--2023-12
( 15 ) 藏茵陈总苦苷有效部位治疗慢性胆囊炎的作用机制研究, 负责人, 国家任务, 2022-01--2025-12
( 16 ) 藏药质量标志物发掘和标准化关键技术及应用示范, 负责人, 地方任务, 2023-01--2025-12
参与会议
(1)无   天津RCEP传统药物国际研讨会   2021-05-15
(2)无   第十二届全国天然有机化学学术会议   2018-07-28
(3)无   中国化学会第十九届全国有机分析及生物分析学术研讨会   2017-03-29
(4)无   中国中西部地区第五届色谱学术报告会   2016-04-30
(5)Separation of A Minor Lignan from Sinopodophyllum emodi Using HSCCC Combined MPLC Guided By HPLC/MS   第十届全国天然有机化学学术会议   Yongling Liu   2014-10-15
(6)HIGH-SPEED COUNTER-CURRENT CHROMATOGRAPHY PREPARATIVE ISOLATION AND PURIFICATION OF FOUR XANTHONE GLYCOSIDES FROM TIBETAN MEDICINAL PLANT HALENIA ELLIPTICA   2012年国际逆流色谱学术会议   Yulin LI   2012-08-08
(7)藏药“藏茵陈”化学成分的HPLC/MS分析表征及HSCCC高效分离制备研究   2011年全国药物化学学术会议暨第三届中英药物化学学术会议   李玉林、王萍、刘永玲   2011-11-17