基本信息
彭红丽 女 硕导 中国科学院上海药物研究所
email: penghl@mail.shcnc.ac.cn
address: 上海市祖冲之路555号
postalCode: 201203
email: penghl@mail.shcnc.ac.cn
address: 上海市祖冲之路555号
postalCode: 201203
教育背景
1996-11--2000-10 丹麦Aarhus大学医学院 博士1988-09--1991-07 上海医科大学药学院 硕士1982-09--1986-07 复旦大学生物系 学士
工作经历
工作简历
2005-01~现在, 中国科学院上海药物研究所, 副研究员2000-10~2004-12,美国Boston大学医学院, 博士后1996-11~2000-10,丹麦Aarhus大学医学院, 博士1995-08~1996-10,丹麦Aarhus大学医学院药理系, 访问学者1991-07~1995-07,上海医科大学药学院, 讲师1988-09~1991-07,上海医科大学药学院, 硕士1986-07~1988-08,湖南医科大学生理系, 助教1982-09~1986-07,复旦大学生物系, 学士
社会兼职
2010-09-25-2011-09-30,上海市科学技术委员会, 技术预见专家
2010-05-01-2012-05-31,教育部“留学回国人员科研启动基金”, 评审专家
2010-05-01-2012-05-31,教育部“留学回国人员科研启动基金”, 评审专家
专利与奖励
专利成果
( 1 ) 黄芩甙及黄芩素衍生物的医学用途, 2011, 第 1 作者, 专利号: 证书号第730740 号( 2 ) 2. 一类取代哌嗪类化合物、其制备方法、用途及包含此类化合物的药物组合物, 2008, 第 5 作者, 专利号: CN101318943
出版信息
发表论文
(1) Asymmetric synthesis and biological evaluation of N-cyclohexyl-4-1-(2,4-dichlorophenyl)-1-(p-tolyl)methylpiperazine-1-carboxamide as hCB1 receptor antagonists, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 第 4 作者(2) Effect of baicalin on serum glucose,cholesterol and activation of AMPK in streptozotocin-induced type 2 diabetic rats, Chin J Pharmaco Toxicol, 2011, 第 11 作者(3) Novel synthetic baicalein derivatives caused apoptosis and activated AMP-activated protein kinase in human tumor cells, ORGANIC & BIOMOLECULAR CHEMISTRY, 2011, 第 11 作者(4) Reduction of Lipid Accumulation in HepG2 Cells by Luteolin is associated with Activation of AMPK and Mitigation of Oxidative Stress, PHYTOTHERAPY RESEARCH, 2011, 第 11 作者(5) Modulation of Ca2+ release through ryanodine receptors in vascular smooth muscle by protein kinase C alpha, PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2010, 第 1 作者(6) Discovery of benzhydrylpiperazine derivatives as CB 1 receptor inverse agonists via privileged structure-based approach, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 第 11 作者(7) Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet, Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet, 中国药理学报:英文版, 2009, (8) Junctional and nonjunctional effects of heptanol and glycyrrhetinic acid derivates in rat mesenteric small arteries, BRITISH JOURNAL OF PHARMACOLOGY, 2004, (9) Hypothesis for the initiation of vasomotion, CIRCULATION RESEARCH, 2001, (10) Effect of acidosis on tension and Ca2+(i) in rat cerebral arteries: is there a role for membrane potential?, AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1998, (11) On the cellular mechanism for the effect of acidosis on vascular tone, ACTA PHYSIOLOGICA SCANDINAVICA, 1998, (12) pH and smooth muscle, ACTA PHYSIOLOGICA SCANDINAVICA, 1997, (13) Anti-lipid peroxidation of gomisin J on liver mitochondria and cultured myocardial cells, ACTA PHARMACOLOGICA SINICA, 1996, (14) Anti-lipid peroxidation effect of ��-selenocarrageenan in mice., Chinese Journal of Pharmacology and Toxicologyy, 1995, 第 1 作者(15) DETERMINATION OF BETA-ADRENOCEPTOR SUBTYPES IN HUMAN PULMONARY-ARTERY AND THORACIC AORTA BY RADIOLIGAND BINDING, ACTA PHARMACOLOGICA SINICA, 1993, (16) 硒化卡拉胶对果蝇的吃食,交配和寿命的影响, 癌变.畸变.突变, 1993, (17) Effect of tetrahydrobarbarine on beta-adrenoceptors, Chinese Journal of Pharmacology and Toxicology, 1991, 第 1 作者
科研活动
科研项目
( 1 ) 新型选择性组蛋白去乙酰化酶抑制剂对抑癌基因LKB1调控的分子机制研究, 负责人, 国家任务, 2012-01--2015-12( 2 ) 关键技术: 手性化合物合成与生物活性评价技术(子课题), 负责人, 国家任务, 2008-11--2010-12( 3 ) 新型骨架结构大麻素受体-1 拮抗剂先导化合物的优化, 负责人, 国家任务, 2007-06--2010-11