周琪  男  研究员,博导,中国科学院院士  中国科学院动物研究所
电子邮件: zhouqi@ioz.ac.cn
通信地址: 北京市朝阳区大屯路甲3号院 中国科学院干细胞与再生医学创新研究院
邮政编码: 100101

研究领域

    生殖、发育、干细胞的基础研究与转化应用。

招生信息

   
招生专业
0710J6-再生医学
071008-发育生物学
招生方向
干细胞与再生医学

工作经历

   

教授课程

干细胞生物学
科学前沿进展名家系列讲座I
科学前沿进展名家系列讲座Ⅱ
干细胞研究进展系列讲座

专利与奖励

   

出版信息

   
发表论文
[1] Fei Teng, Tongtong Cui, Li Zhou, Qingqin Gao, Qi Zhou, Wei Li. Programmable synthetic receptors: the next-generation of cell and gene therapies. SIGNAL TRANSDUCTION AND TARGETED THERAPY[J]. 2024, 第 5 作者  通讯作者  9(1): 1-25, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761793/.
[2] Xuehan Sun, Chen Liang, Yangcan Chen, Tongtong Cui, Jiabao Han, Moyu Dai, Ying Zhang, Qi Zhou, Wei Li. Knockout and replacement gene surgery to treat rhodopsin-mediated autosomal dominant retinitis pigmentosa. Human Gene Therapy[J]. 2024, 第 8 作者  通讯作者  35(5-6): 151-162, 
[3] Yaojin Peng, Aijin Ma, Zhenyu Xiao, Jie Hao, Ruohan Feng, Changlin Wang, Baoyang Hu, Peijun Zhai, Ka Li, Lei Wang, Jiani Cao, Peng Xiang, Yu Zhang, Jun Wei, Xiaolong Wang, Boqiang Fu, Qubo Chen, Qiang Wei, Hengjun Gao, Jianwei Lv, Xing Liu, Yonghui Ma, Tao Cheng, Xiaoru Huang, Yeyang Su, Haihong Zhang, Qi Zhou, Tongbiao Zhao. Technical specifications for ethics review of human stem cell research. Cell Proliferation[J]. 2024, 第 27 作者  通讯作者  57(3): e13556, 
[4] Yangcan Chen, Shengqiu Luo, Yanping Hu, Bangwei Mao, Xinge Wang, Zongbao Lu, Qingtong Shan, Jin Zhang, Siqi Wang, Guihai Feng, Chenxin Wang, Chen Liang, Na Tang, Rui Niu, Jiaqiang Wang, Jiabao Han, Ning Yang, Haoyi Wang, Qi Zhou, Wei Li. All-RNA-mediated targeted gene integration in mammalian cells with rationally engineered R2 retrotransposons. Cell[J]. 2024, 第 19 作者  通讯作者  187(17): 4674-4689.e18, 
[5] Jiaqiang Wang, Yiwei Zhang, Jiaze Gao, Guihai Feng, Chao Liu, Xueke Li, Pengcheng Li, Zhonghua Liu, Falong Lu, Leyun Wang, Wei Li, Qi Zhou, Yusheng Liu. Alternative splicing of CARM1 regulated by LincGET -guided paraspeckles biases the first cell fate in mammalian early embryos. NATURE STRUCTURAL & MOLECULAR BIOLOGY[J]. 2024, 第 12 作者  通讯作者  31(9): 1341-1354, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11402786/.
[6] Huang, Cheng, Jiang, Haiping, Dong, Jingxi, Jiang, Liyuan, Li, Jie, Xu, Jing, Cui, Tongtong, Wang, Leyun, Li, Xin, Feng, Guihai, Zhang, Ying, Li, Tianda, Li, Wei, Zhou, Qi. Functional mouse hepatocytes derived from interspecies chimeric livers effectively mitigate chronic liver fibrosis. STEM CELL REPORTS[J]. 2024, 第 14 作者  通讯作者  19(6): 877-889, http://dx.doi.org/10.1016/j.stemcr.2024.04.006.
[7] Tingting Gao, Xiyuan Zhao, Jie Hao, Yao Tian, Huike Ma, Wenjing Liu, Bin An, Faguo Sun, Shasha Liu, Baojie Guo, Shuaishuai Niu, Zhongwen Li, Chenxin Wang, Yukai Wang, Guihai Feng, Liu Wang, Wei Li, Jun Wu, Meijin Guo, Qi Zhou, Qi Gu. A scalable culture system incorporating microcarrier for specialised mesenchymal stem cells from human embryonic stem cells. MATERIALS TODAY BIO[J]. 2023, 第 20 作者  通讯作者  20:100662: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196860/.
[8] Jiang, Liyuan, Wang, Xin, Wang, Leyun, Ma, Sinan, Ding, Yali, Liu, Chao, Wang, Siqi, Shao, Xuan, Zhang, Ying, Li, Zhikun, Li, Wei, Feng, Guihai, Zhou, Qi. Deciphering the placental abnormalities associated with somatic cell nuclear transfer at single-nucleus resolution. PROTEIN & CELL[J]. 2023, 第 13 作者  通讯作者  pwad030: http://dx.doi.org/10.1093/procel/pwad030.
[9] Sunyang Ying, Pengcheng Li, Jiaqiang Wang, Kaiqiong Chen, Yu Zou, Moyu Dai, Kai Xu, Guihai Feng, Changjian Zhang, Haiping Jiang, Wei Li, Ying Zhang, Qi Zhou. tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis. SIGNAL TRANSDUCTION AND TARGETED THERAPY[J]. 2023, 第 13 作者  通讯作者  8(1): 144, http://dx.doi.org/10.1038/s41392-023-01351-5.
[10] Sun, Hao, Zhang, Zhuo, Li, Tianda, Li, Ting, Chen, Weicai, Pan, Tianshi, Fang, Sen, Liu, Chao, Zhang, Ying, Wang, Leyun, Feng, Guihai, Li, Wei, Zhou, Qi, Zhao, Yuzheng. Live-cell imaging reveals redox metabolic reprogramming during zygotic genome activation. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2023, 第 13 作者  通讯作者  238(9): 2039-2049, http://dx.doi.org/10.1002/jcp.31054.
[11] Ji, TianTian, Niu, ShuaiShuai, Fang, MingHui, Xu, LingXue, Wang, Xin, Wu, Jun, Xu, Fei, Zhang, Meng, Niu, Rui, Wu, Jun, Wang, Lei, Li, ZhiKun, Yang, YongGuang, Hao, Jie, Li, Wei, Hu, Zheng, Zhou, Qi. Genome editing HLA alleles for a pilot immunocompatible hESC line in a Chinese hESC bank for cell therapies. CELL PROLIFERATION[J]. 2023, 第 17 作者  通讯作者  56(5): e13471, https://www.doi.org/10.1111/cpr.13471.
[12] Wang, Chenxin, Fang, Sen, Chen, Yangcan, Tang, Na, Jiao, Guanyi, Hu, Yanping, Li, Jing, Shan, Qingtong, Wang, Xin, Feng, Guihai, Zhou, Qi, Li, Wei. High-efficiency targeted transgene integration via primed micro-homologues. CELL DISCOVERY[J]. 2023, 第 11 作者  通讯作者  9(1): 69, http://dx.doi.org/10.1038/s41421-023-00552-0.
[13] Yangcan Chen, Yanping Hu, Shengqiu Luo, Xinge Wang, Bangwei Mao, Yi Chen, Jing Xu, Zhikun Li, Qi Zhou, Wei Li. Computer-aided engineering of CRISPR-Cas proteins for enhanced human genome editing. 中国科学:生命科学英文版[J]. 2023, 第 9 作者  通讯作者  66(4): 883-886, http://lib.cqvip.com/Qikan/Article/Detail?id=7109454744.
[14] Peng, Yaojin, Lv, Jianwei, Ding, Lulu, Gong, Xia, Zhou, Qi. Responsible governance of human germline genome editing in China(dagger). BIOLOGY OF REPRODUCTION[J]. 2022, 第 5 作者  通讯作者  107(1): 261-268, http://dx.doi.org/10.1093/biolre/ioac114.
[15] Yanping Hu, Yangcan Chen, Jing Xu, Xinge Wang, Shengqiu Luo, Bangwei Mao, Qi Zhou, Wei Li. Metagenomic discovery of novel CRISPR-Cas13 systems. CELLDISCOVERY[J]. 2022, 第 7 作者  通讯作者  8(1): 1-4, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554183/.
[16] Ying Li, Jie Hao, Zheng Hu, YongGuang Yang, Qi Zhou, Liguang Sun, Jun Wu. Current status of clinical trials assessing mesenchymal stem cell therapy for graft versus host disease: a systematic review. STEM CELL RESEARCH & THERAPY[J]. 2022, 第 5 作者  通讯作者  13(1): http://dx.doi.org/10.1186/s13287-022-02751-0.
[17] Jiabao Han, Liyu Zhu, Jingwen Zhang, Lu Guo, Xuehan Sun, Cheng Huang, Kai Xu, Ying Zhang, Wei Li, Qi Zhou. Rational engineering of adeno-associated virus capsid enhances human hepatocyte tropism and reduces immunogenicity. Cell Proliferation[J]. 2022, 第 10 作者  通讯作者  55(12): e13339-0, 
[18] Zhou, Qi. Progress in modern reproductive biology research in China(dagger). BIOLOGY OF REPRODUCTION[J]. 2022, 第 1 作者  通讯作者  107(1): 3-11, http://dx.doi.org/10.1093/biolre/ioac122.
[19] Yaojin Peng, Jianwei Lv, Zhenyu Xiao, Lulu Ding, Qi Zhou. A framework for the responsible reform of the 14-day rule in human embryo research. Protein & Cell[J]. 2022, 第 5 作者  通讯作者  13(8): 552-558, 
[20] ZhengQuan He, XueWei Yuan, ZongBao Lu, YuHuan Li, YuFei Li, Xin Liu, Liu Wang, Ying Zhang, Qi Zhou, Wei Li. Pharmacological regulation of tissue fibrosis by targeting the mechanical contraction of myofibroblasts. FUNDAMENTAL RESEARCH[J]. 2022, 第 9 作者  通讯作者  2(1): 37-47, 
[21] Stacey, Glyn N, Cao, Jingyi, Hu, Baoyang, Zhou, Qi. Manufacturing with pluripotent stem cells (PSConf 2021): Key issues for future research and development. CELL PROLIFERATION[J]. 2022, 第 4 作者  通讯作者  55(8): http://dx.doi.org/10.1111/cpr.13301.
[22] Lu Guo, Zhikun Li, Yuhuan Li, Bin Qu, Guanyi Jiao, Chen Liang, Zongbao Lu, XinGe Wang, Cheng Huang, Hongwei Du, Jianmin Liang, Qi Zhou, Wei Li. Treatment of Glutaric Aciduria Type I (GA-I) via Intracerebroventricular Delivery of GCDH. FUNDAMENTAL RESEARCH[J]. 2022, 第 12 作者  通讯作者  http://dx.doi.org/10.1016/j.fmre.2022.08.013.
[23] Chen, Yangcan, Hu, Yanping, Wang, Xinge, Luo, Shengqiu, Yang, Ning, Chen, Yi, Li, Zhikun, Zhou, Qi, Li, Wei. Synergistic engineering of CRISPR-Cas nucleases enables robust mammalian genome editing. Innovation (Camb)[J]. 2022, 第 8 作者  通讯作者  3(4): 100264, 
[24] He, ZhengQuan, Li, YuHuan, Feng, GuHai, Yuan, XueWei, Lu, ZongBao, Dai, Min, Hu, YanPing, Zhang, Ying, Zhou, Qi, Li, Wei. Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons. ADVANCED SCIENCE[J]. 2022, 第 9 作者  通讯作者  9(13): http://dx.doi.org/10.1002/advs.202104682.
[25] Zhu, Haibo, Sun, Hao, Yu, Dawei, Li, Tianda, Hai, Tang, Liu, Chao, Zhang, Ying, Chen, Yurong, Dai, Xiangpeng, Li, Ziyi, Li, Wei, Liu, Ruizhi, Feng, Guihai, Zhou, Qi. Transcriptome and DNA Methylation Profiles of Mouse Fetus and Placenta Generated by Round Spermatid Injection. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY[J]. 2021, 第 14 作者  通讯作者  9: 0-0, 
[26] Mao, Yihuan, Wang, Libin, Zhong, Bei, Yang, Ning, Li, Zhikun, Cui, Tongtong, Feng, Guihai, Li, Wei, Zhang, Ying, Zhou, Qi. Continuous expression of reprogramming factors induces and maintains mouse pluripotency without specific growth factors and signaling inhibitors. CELL PROLIFERATION[J]. 2021, 第 10 作者  通讯作者  54(8): http://dx.doi.org/10.1111/cpr.13090.
[27] Cao, Jiani, Hao, Jie, Wang, Lei, Tan, Yuanqing, Tian, Yuchang, Li, Shiyu, Ma, Aijin, Fu, Boqiang, Dai, Jianwu, Zhai, Peijun, Xiang, Peng, Zhang, Yong, Cheng, Tao, Peng, Yaojin, Zhou, Qi, Zhao, Tongbiao. Developing standards to support the clinical translation of stem cells. STEM CELLS TRANSLATIONAL MEDICINE[J]. 2021, 第 15 作者  通讯作者  10(Suppl 2): S85-S95, http://dx.doi.org/10.1002/sct3.13035.
[28] Wang, LeYun, Li, ZhiKun, Wang, LiBin, Liu, Chao, Sun, XueHan, Feng, GuiHai, Wang, JiaQiang, Li, YuFei, Qiao, LianYong, Nie, Hu, Jiang, LiYuan, Sun, Hao, Xie, YaLi, Ma, SiNan, Wan, HaiFeng, Lu, FaLong, Li, Wei, Zhou, Qi. Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer. CELL STEM CELL[J]. 2020, 第 18 作者  通讯作者  27(2): 315-325.e5, http://dx.doi.org/10.1016/j.stem.2020.05.014.
[29] Li, Yufei, Li, Wei, Zhou, Qi. Haploid pluripotent stem cells: twofold benefits with half the effort in genetic screening and reproduction. CURRENT OPINION IN GENETICS & DEVELOPMENT[J]. 2020, 第 3 作者  通讯作者  64: 6-12, http://dx.doi.org/10.1016/j.gde.2020.05.013.
[30] Fu, Rui, Yu, Dawei, Ren, Jilong, Li, Chongyang, Wang, Jing, Feng, Guihai, Wang, Xuepeng, Wan, Haifeng, Li, Tianda, Wang, Libin, Zhang, Ying, Hai, Tang, Li, Wei, Zhou, Qi. Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs. PROTEIN & CELL[J]. 2020, 第 14 作者  通讯作者  11(2): 97-107, http://lib.cqvip.com/Qikan/Article/Detail?id=7101576097.
[31] Peng, YaoJin, Huang, Xiaoru, Zhou, Qi. Ethical and Policy Considerations for Human Embryo and Stem Cell Research in China. CELL STEM CELL[J]. 2020, 第 3 作者  通讯作者  27(4): 511-514, http://dx.doi.org/10.1016/j.stem.2020.09.010.
[32] Li, Jing, Wang, Chenxin, Feng, Guihai, Zhang, Linlin, Chen, Guilai, Sun, Hao, Wang, Jiaqiang, Zhang, Ying, Zhou, Qi, Li, Wei. Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing. CELL PROLIFERATION[J]. 2020, 第 9 作者  通讯作者  53(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000500078600001.
[33] Zhongwen Li, Jun Wu, Lei Wang, Weifang Han, Juan Yu, Xin Liu, Yukai Wang, Ying Zhang, Guihai Feng, Wei Li, Glyn Nigel Stacey, Qi Gu, Baoyang Hu, Liu Wang, Qi Zhou, Jie Hao. Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions. CELLDEATHANDDISEASE[J]. 2019, 第 15 作者  通讯作者  10(10): 1-14, http://dx.doi.org/10.1038/s41419-019-1967-5.
[34] Fei Teng, Wei Li, Qi Zhou. Synthetic chromosome evolves the yeast genome. 中国科学:生命科学英文版[J]. 2019, 第 3 作者  通讯作者  708-709, http://lib.cqvip.com/Qikan/Article/Detail?id=74678871504849574853484951.
[35] Li, Yufei, Wang, Leyun, Zhang, Linlin, He, Zhengquan, Feng, Guihai, Sun, Hao, Wang, Jiaqiang, Li, Zhikun, Liu, Chao, Han, Jiabao, Mao, Junjie, Li, Pengcheng, Yuan, Xuewei, Jiang, Liyuan, Zhang, Ying, Zhou, Qi, Li, Wei. Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I. JOURNAL OF CELL BIOLOGY[J]. 2019, 第 16 作者  通讯作者  218(5): 1553-1563, https://www.webofscience.com/wos/woscc/full-record/WOS:000466980400014.
[36] Teng, Fei, Li, Jing, Cui, Tongtong, Xu, Kai, Guo, Lu, Gao, Qingqin, Feng, Guihai, Chen, Chuanyuan, Han, Dali, Zhou, Qi, Li, Wei. Enhanced mammalian genome editing by new Cas12a orthologs with optimized crRNA scaffolds. GENOME BIOLOGY[J]. 2019, 第 10 作者  通讯作者  20(1): 15, https://doaj.org/article/ef19e2ad7d1c4c9788a858a91d36f8cb.
[37] Lei Wang, Wei Wu, Qi Gu, Zengping Liu, Qiyou Li, Zhongwen Li, Jinhui Fang, Wenjing Liu, Jun Wu, Ying Zhang, Liu Wang, Haiwei Xu, Wei Li, Baoyang Hu, Qi Zhou, Zhengqin Yin, Jie Hao. The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies. 蛋白质与细胞:英文版[J]. 2019, 第 15 作者  通讯作者  10(6): 455-460, http://lib.cqvip.com/Qikan/Article/Detail?id=7002265647.
[38] Teng, Fei, Guo, Lu, Cui, Tongtong, Wang, XinGe, Xu, Kai, Gao, Qingqin, Zhou, Qi, Li, Wei. CDetection: CRISPR-Cas12b-based DNA detection with sub-attomolar sensitivity and single-base specificity. GENOME BIOLOGY[J]. 2019, 第 7 作者  通讯作者  20(1): 132, http://dx.doi.org/10.1186/s13059-019-1742-z.
[39] Wenliang Zhu, Boya Zhang, Mengqi Li, Fan Mo, Tingwei Mi, Yihui Wu, Zhaoqian Teng, Qi Zhou, Wei Li, Baoyang Hu. Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome. NATURE COMMUNICATIONS[J]. 2019, 第 8 作者  通讯作者  10(1): 1-18, https://doaj.org/article/fe289d2c0c864031a37e09fb8593c020.
[40] Cui, Tongtong, Jiang, Liyuan, Li, Tianda, Teng, Fei, Feng, Guihai, Wang, Xuepeng, He, Zhengquan, Guo, Lu, Xu, Kai, Mao, Yihuan, Wang, Leyun, Yuan, Xuewei, Wang, Liu, Li, Wei, Zhou, Qi. Derivation of Mouse Haploid Trophoblast Stem Cells. CELL REPORTS[J]. 2019, 第 15 作者  通讯作者  26(2): 407-414.e5, http://dx.doi.org/10.1016/j.celrep.2018.12.067.
[41] Teng, Fei, Cui, Tongtong, Gao, Qingqin, Guo, Lu, Zhou, Qi, Li, Wei. Artificial sgRNAs engineered for genome editing with new Cas12b orthologs. CELL DISCOVERY[J]. 2019, 第 5 作者  通讯作者  5: 23, https://doaj.org/article/e8ef22cb7fda4f2b987b008ac5d4e070.
[42] Yuan, Xuewei, He, Zhengquan, Mao, Junjie, Hu, Yanping, Liu, Xin, Guo, Jia, Liu, Zhonghua, Zhang, Ying, Li, Wei, Zhou, Qi. Reprogramming of fibroblasts to uterine glandular epithelium by a chemical cocktail induction. CELL DISCOVERY[J]. 2019, 第 10 作者  通讯作者  5: 26, http://dx.doi.org/10.1038/s41421-019-0096-8.
[43] TiANDa Li, Leyun Wang, Xinxin Zhang, Liyuan Jiang, Yufei Li, Junjie Mao, Tongtong Cui, Wei Li, Liu Wang, Qi Zhou. Generation of rat-mouse chimeras by introducing single cells of rat inner cell masses into mouse blastocysts. Journal of Genetics and Genomics[J]. 2018, 第 10 作者  通讯作者  45(6): 325-328, http://lib.cqvip.com/Qikan/Article/Detail?id=675742569.
[44] Zhou Qi. Mitochondrially produced ATP affects stem cell pluripotency via Actl6a-mediated histone acetylation. FASEB J. 2018, 第 1 作者  通讯作者  
[45] Guanghai Xiang, Jilong Ren, Tang Hai, Rui Fu, Dawei Yu, Jing Wang, Wei Li, Haoyi Wang, Qi Zhou. Editing porcine IGF2 regulatory element improved meat production in Chinese Bama pigs. CELLULAR AND MOLECULAR LIFE SCIENCES: CMLS[J]. 2018, 第 9 作者  通讯作者  75(24): 4619-4628, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11105340/.
[46] Zhang, Wei, Feng, Guihai, Wang, Libin, Teng, Fei, Wang, Liu, Li, Wei, Zhang, Ying, Zhou, Qi. MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation. JOURNALOFMOLECULARCELLBIOLOGY[J]. 2018, 第 8 作者  通讯作者  10(6): 515-526, https://www.webofscience.com/wos/woscc/full-record/WOS:000455316500004.
[47] Xia Li, Ruoyu Ma, Qi Gu, Lingmin Liang, Lei Wang, Ying Zhang, Xianning Wang, Xin Liu, Zhongwen Li, Jinhui Fang, Jun Wu, Yukai Wang, Wei Li, Baoyang Hu, Liu Wang, Qi Zhou, Jie Hao. A fully defined static suspension culture system for large-scale human embryonic stem cell production. CELL DEATH AND DISEASE[J]. 2018, 第 16 作者  通讯作者  9(9): 1-9, https://doaj.org/article/517fbb632f3142c385073e2f1824afd8.
[48] Zhang, Yunfang, Zhang, Xudong, Shi, Junchao, Tuorto, Francesca, Li, Xin, Liu, Yusheng, Liebers, Reinhard, Zhang, Liwen, Qu, Yongcun, Qian, Jingjing, Pahima, Maya, Liu, Ying, Yan, Menghong, Cao, Zhonghong, Lei, Xiaohua, Cao, Yujing, Peng, Hongying, Liu, Shichao, Wang, Yue, Zheng, Huili, Woolsey, Rebekah, Quilici, David, Zhai, Qiwei, Li, Lei, Zhou, Tong, Yan, Wei, Lyko, Frank, Zhang, Ying, Zhou, Qi, Duan, Enkui, Chen, Qi. Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs. NATURE CELL BIOLOGY[J]. 2018, 第 29 作者  通讯作者  20(5): 535-+, http://dx.doi.org/10.1038/s41556-018-0087-2.
[49] Zhang, Ying, Guo, Lu, Li, Yuhuan, Feng, GuiHai, Teng, Fei, Li, Wei, Zhou, Qi. MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer. MOLECULAR CANCER[J]. 2018, 第 7 作者  通讯作者  17(1): https://doaj.org/article/f9ae56d34daf40d7918e42f9a6ba1416.
[50] Li, ZhiKun, Wang, LeYun, Wang, LiBin, Feng, GuiHai, Yuan, XueWei, Liu, Chao, Xu, Kai, Li, YuHuan, Wan, HaiFeng, Zhang, Ying, Li, YuFei, Li, Xin, Li, Wei, Zhou, Qi, Hu, BaoYang. Generation of Bimaternal and Bipaternal Mice from Hypomethylated Haploid ESCs with Imprinting Region Deletions. CELL STEM CELL[J]. 2018, 第 14 作者  通讯作者  23(5): 665-+, http://dx.doi.org/10.1016/j.stem.2018.09.004.
[51] Wang, ChenXin, Cui, GuanShen, Liu, XiuYing, Xu, Kai, Wang, Meng, Zhang, XinXin, Jiang, LiYuan, Li, Ang, Yan, Ying, Lai, WeiYi, Sun, BaoFa, Jiang, GuiBin, Wang, HaiLin, Tong, WeiMin, Li, Wei, Wang, XiuJie, Yang, YunGui, Zhou, Qi. METTL3-mediated m6A modification is required for cerebellar development. PLoS Biology[J]. 2018, 第 18 作者  通讯作者  16(6): https://doaj.org/article/ac22537f22f14d259073b36f082d0530.
[52] Tan, Yuanqing, Han, Pengcheng, Gu, Qi, Chen, Gang, Wang, Lei, Ma, Ruoyu, Wu, Jun, Feng, Chunjing, Zhang, Ying, Wang, Liu, Hu, Baoyang, Li, Wei, Hao, Jie, Zhou, Qi. Generation of clinical-grade functional cardiomyocytes from human embryonic stem cells in chemically defined conditions. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE[J]. 2018, 第 14 作者  通讯作者  12(1): 153-163, https://www.webofscience.com/wos/woscc/full-record/WOS:000423431200070.
[53] Wang, YuKai, Zhu, WanWan, Wu, MengHua, Wu, YiHui, Liu, ZhengXin, Liang, LingMin, Sheng, Chao, Hao, Jie, Wang, Liu, Li, Wei, Zhou, Qi, Hu, BaoYang. Human Clinical-Grade Parthenogenetic ESC-Derived Dopaminergic Neurons Recover Locomotive Defects of Nonhuman Primate Models of Parkinson's Disease. STEM CELL REPORTS[J]. 2018, 第 11 作者  通讯作者  11(1): 171-182, http://dx.doi.org/10.1016/j.stemcr.2018.05.010.
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[109] Zhou Qi. Efficient and rapid generation of induced pluripotent stem cells using alternative culture medium.. 2010, 第 1 作者  通讯作者  
[110] Shuya Zhou, Chenhui Ding, Xiaoyang Zhao, Eryao Wang, Xiangpeng Dai, Lei Liu, Wei Li, Zichuan Liu, Haifeng Wan, Chunjing Feng, Tang Hai, Liu Wang, Qi Zhou. Successful generation of cloned mice using nuclear transfer from induced pluripotent stem cells. 细胞研究:英文版[J]. 2010, 第 13 作者850-853, http://lib.cqvip.com/Qikan/Article/Detail?id=34527319.
[111] Zhao, Xiaoyang, Li, Wei, Lv, Zhuo, Liu, Lei, Tong, Man, Hai, Tang, Hao, Jie, Wang, Xiang, Wang, Liu, Zeng, Fanyi, Zhou, Qi. Viable Fertile Mice Generated from Fully Pluripotent iPS Cells Derived from Adult Somatic Cells. STEM CELL REVIEWS AND REPORTS[J]. 2010, 第 11 作者  通讯作者  6(3): 390-397, http://www.corc.org.cn/handle/1471x/2413215.
[112] Xiaoyang Zhao, Zhuo Lv, Lei Liu, Liu Wang, Man Tong, Qi Zhou. Derivation of embryonic stem cells from Brown Norway rats blastocysts. 遗传学报[J]. 2010, 第 6 作者467-473, http://lib.cqvip.com/Qikan/Article/Detail?id=34650360.
[113] Wang, Yingying, Hai, Tang, Liu, Zichuan, Zhou, Shuya, Lv, Zhuo, Ding, Chenhui, Liu, Lei, Niu, Yuyu, Zhao, Xiaoyang, Tong, Man, Wang, Liu, Jouneau, Alice, Zhang, Xun, Ji, Weizhi, Zhou, Qi. HSPC117 deficiency in cloned embryos causes placental abnormality and fetal death. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2010, 第 15 作者397(3): 407-412, http://159.226.149.42:8080/handle/152453/5645.
[114] Niu Yuyu, Yu Yang, Bernat Agnieszka, Yang Shihua, He Xiechao, Guo Xiangyu, Chen Dongliang, Chen Yongchang, Ji Shaohui, Si Wei, Lv Yongqin, Tan Tao, Wei Qiang, Wang Hong, Shi Lei, Guan Jean, Zhu Xuemei, Afanassieff Marielle, Savatier Pierre, Zhang Kang, Zhou Qi, Ji Weizhi. Transgenic rhesus monkeys produced by gene transfer into early-cleavage-stage embryos using a simian immunodeficiency virus-based vector. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2010, 第 21 作者107(41): 17663-17667, http://159.226.149.42:8080/handle/152453/6340.
[115] Zhou Qi. Decreased cofilin1 expression is important for compaction during early mouse embryo development.. 2010, 第 1 作者  通讯作者  
[116] Maruotti, Julien, Dai, Xiang Peng, Brochard, Vincent, Jouneau, Luc, Liu, Jun, BonnetGarnier, Amelie, Jammes, Helene, Vallier, Ludovic, Brons, I Gabrielle M, Pedersen, Roger, Renard, JeanPaul, Zhou, Qi, Jouneau, Alice. Nuclear Transfer-Derived Epiblast Stem Cells Are Transcriptionally and Epigenetically Distinguishable from Their Fertilized-Derived Counterparts. STEM CELLS[J]. 2010, 第 12 作者28(4): 743-752, http://www.corc.org.cn/handle/1471x/2408753.
[117] 周琪. iPS cells produce viable mice through tetraploid complementation. NATURE[J]. 2009, 第 1 作者461(7260): 86-U88, 
[118] Chen, Xinjie, Li, Tianqing, Li, Xuemei, Xie, Yunhua, Guo, Xiangyu, Ji, Shaohui, Niu, Yiyu, Yu, Yang, Ding, Chenhui, Yao, Ruqiang, Yang, Shihua, Ji, Weizhi, Zhou, Qi. Neural progenitors derived from monkey embryonic stem cells in a simple monoculture system. REPRODUCTIVE BIOMEDICINE ONLINE[J]. 2009, 第 13 作者  通讯作者  19(3): 426-433, http://dx.doi.org/10.1016/S1472-6483(10)60179-4.
[119] Lifang Jin, Shaohui Ji, Xianghui Tang, Xiangyu Guo, Yongqing Lu, Hongwei Chen, Hongkui Deng, Qi Zhou, Weizhi Ji. Isolation and characterization of liver epithelial progenitor cells from normal adult rhesus monkeys (Macaca mulatta). 细胞研究:英文版[J]. 2009, 第 8 作者19(2): 268-270, http://lib.cqvip.com/Qikan/Article/Detail?id=29433951.
[120] Zhou Qi. Evaluation of blastomere biopsy using mouse model indicates the potential high-risk of neurodegenerative disorders in the offspring.. 2009, 第 1 作者  通讯作者  
[121] Hao Jie, Zhu WanWan, Sheng Chao, Yu Yang, Zhou Qi. Human parthenogenetic embryonic stem cells: one potential resource for cell therapy. SCIENCE IN CHINA SERIES C-LIFE SCIENCES. 2009, 第 5 作者  通讯作者  52(7): 599-602, http://www.corc.org.cn/handle/1471x/2395693.
[122] Yu, Yang, Mai, Qingyun, Chen, Xinjie, Wang, Liu, Gao, Ling, Zhou, Canquan, Zhou, Qi. Assessment of the developmental competence of human somatic cell nuclear transfer embryos by oocyte morphology classification. HUMAN REPRODUCTION[J]. 2009, 第 7 作者24(3): 649-657, http://dx.doi.org/10.1093/humrep/den407.
[123] Dai, Xiangpeng, Hao, Jie, Zhou, Qi. A modified culture method significantly improves the development of mouse somatic cell nuclear transfer embryos. REPRODUCTION[J]. 2009, 第 3 作者  通讯作者  138(2): 301-308, https://www.webofscience.com/wos/woscc/full-record/WOS:000268344700011.
[124] Wang, Shufen, Shen, Yi, Yuan, Xiaohua, Chen, Kai, Guo, Xiangyu, Chen, Yongchang, Niu, Yuyu, Li, Jian, Xu, RenHe, Yan, Xiyun, Zhou, Qi, Ji, Weizhi. Dissecting Signaling Pathways That Govern Self-renewal of Rabbit Embryonic Stem Cells. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2008, 第 11 作者283(51): 35929-35940, http://dx.doi.org/10.1074/jbc.M804091200.
[125] Ma, Minyue, Guo, Xuejiang, Wang, Fuqiang, Zhao, Chun, Liu, Zichuan, Shi, Zhonghua, Wang, Yufeng, Zhang, Ping, Zhang, Kemei, Wang, Ningling, Lin, Min, Zhou, Zuomin, Liu, Jiayin, Li, Qingzhang, Wang, Liu, Huo, Ran, Sha, Jiahao, Zhou, Qi. Protein Expression Profile of the Mouse Metaphase-II Oocyte. JOURNAL OF PROTEOME RESEARCH[J]. 2008, 第 18 作者  通讯作者  7(11): 4821-4830, https://www.webofscience.com/wos/woscc/full-record/WOS:000260792000021.
[126] Niu, Yuyu, Yang, Shihua, Yu, Yang, Ding, Chenhui, Yang, Jifeng, Wang, Shufen, Ji, Shaohui, He, Xiechao, Xie, Yunhua, Tang, Xianghui, Zhou, Qi, Ji, Weizhi. Impairments in embryonic genome activation in rhesus monkey somatic cell nuclear transfer embryos. CLONING AND STEM CELLS[J]. 2008, 第 11 作者  通讯作者  10(1): 25-35, http://159.226.149.42:8080/handle/152453/5629.
[127] Fan Yong, Tong Man, Zhao ChunLi, Ding ChenHui, Hao Jie, Lv Zhuo, Dai XiangPeng, Hai Tang, Li XueMei, Yao RuQiang, Yu Yang, Li ZanDong, Wang Liu, Alice, Jouneau, Zhou Qi. Comparative pluripotency analysis of mouse embryonic stem cells derived from wild-type and infertile hermaphrodite somatic cell nuclear transfer blastocysts. CHINESE SCIENCE BULLETIN[J]. 2008, 第 15 作者  通讯作者  53(23): 3648-3655, https://www.webofscience.com/wos/woscc/full-record/WOS:000261257600007.
[128] Yang, S, Shen, Y, Niu, Y, Hildebrandt, T B, Jewgenow, K, Goeritz, F, He, X, Zhou, Q, Ji, W. Effects of rhFSH regimen and time interval on ovarian responses to repeated stimulation cycles in rhesus monkeys during a physiologic breeding season. THERIOGENOLOGY[J]. 2008, 70(1): 108-114, http://dx.doi.org/10.1016/j.theriogenology.2008.03.012.
[129] Zhou Qi. Epigenetic marks in cloned rhesus monkey embryos: comparison with counterparts produced in vitro.. Biol Reprod.. 2007, 第 1 作者  通讯作者  
[130] 周琪. Derivation of human embryonic stem cell lines from parthenogenetic blastocysts. CELL RESEARCH[J]. 2007, 第 1 作者17(12): 1008-1019, http://lib.cqvip.com/Qikan/Article/Detail?id=26035178.
[131] Yang, Shihua, He, Xiechao, Hildebrandt, Thomas B, Zhou, Qi, Ji, Weizhi. Superovulatory response to a low dose single-daily treatment of rhFSH dissolved in polyvinylpyrrolidone in rhesus monkeys. AMERICAN JOURNAL OF PRIMATOLOGY[J]. 2007, 第 4 作者69(11): 1278-1284, http://159.226.149.42:8080/handle/152453/5607.
[132] Yang, S, He, X, Hildebrandt, T B, Jewgenow, K, Goeritz, F, Tang, X, Zhou, Q, Ji, W. Effects of rhFSH dose on ovarian follicular response, oocyte recovery and embryo development in rhesus monkeys. THERIOGENOLOGY[J]. 2007, 67(6): 1194-1201, http://dx.doi.org/10.1016/j.theriogenology.2006.10.021.
[133] Zhou, Q, Yang, S H, Ding, C H, He, X C, Xie, Y H, Hildebrandt, T B, Mitalipov, S M, Tang, X H, Wolf, D P, Ji, W Z. A comparative approach to somatic cell nuclear transfer in the rhesus monkey. HUMAN REPRODUCTION[J]. 2006, 21(10): 2564-2571, http://159.226.149.42:8080/handle/152453/5591.
[134] Li, TQ, Wang, SF, Xie, YH, Lu, YQ, Zhang, XZ, Wang, L, Yang, SH, Wolf, D, Zhou, Q, Ji, WZ. Homologous feeder cells support undifferentiated growth and pluripotency in monkey embryonic stem cells. STEM CELLS[J]. 2005, 23(8): 1192-1199, http://159.226.149.42:8080/handle/152453/5577.
[135] Li TQ, Zheng JW, Xie YH, Wang SF, Zhang XZ, Li J, Jin LF, Ma YY, Wolf DP, Zhou Qi, Ji WZ. Transplantable neural progenitor populations derived from Rhesus monkey embryonic stem cells. STEM CELLS[J]. 2005, 第 10 作者23(9): 1295-1303, http://159.226.149.42:8080/handle/152453/5575.
[136] Zhou Qi, Renard JP, Le Friec G, Brochard V, Beaujean N, Cherifi Y, Fraichard A, Cozzi J. Generation of fertile cloned rats by regulating oocyte activation. SCIENCE[J]. 2003, 第 1 作者302(5648): 1179-1179, https://www.webofscience.com/wos/woscc/full-record/WOS:000186544300044.
[137] Zhou Qi. Nuclear Transfer: New Advances and Quandaries.. 2003, 第 1 作者  通讯作者  
[138] Zhou, Q, Jouneau, A, Brochard, V, Adenot, P, Renard, JP. Developmental potential of mouse embryos reconstructed from metaphase embryonic stem cell nuclei. BIOLOGY OF REPRODUCTION[J]. 2001, 65(2): 412-419, https://www.webofscience.com/wos/woscc/full-record/WOS:000170205700011.
[139] Zhou Qi. A simplified method for the reconstruction of fully competent mouse zygotes from adult somatic donor nuclei.. 2000, 第 1 作者
[140] Riaz AbrZhao XYbrDai XPbrLi WbrLiu LbrWan HFbrYu YbrWang LbrZhou Q. Mouse cloning and somatic cell reprogramming using electrofused blastomeres. CELL RESEARCH. 
[141] Jiang Ming-Gui, Li Tianda, Feng Chunjing, Fu Rui, Yuan Yan, Zhou Quan, Li Xin, Wan Haifeng, Wang Liu, Li Wei, Xiao Yamei, Zhao Xiao-Yang, Zhou Qi. Generation of Transgenic Rats through Induced Pluripotent Stem Cells *. THE JOURNAL OF BIOLOGICAL CHEMISTRY. 第 13 作者288(38): 27150-27158, http://dx.doi.org/10.1074/jbc.M113.492900.
发表著作
(1) 神秘的克隆, Clone, 中国教育科学出版社, 1997-08, 第 1 作者
(2) 干细胞实验指南, Handbook: Stem Cell Biology, 中央广播电视大学出版社, 2015-07, 第 1 作者

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