本人从事医学CT成像方法研究，包括模型驱动图像重建、人工智能驱动图像重建、低剂量CT成像、能谱CT成像、脑血管与脑灌注成像，心血管与心肌灌注成像等，形成了“理论研究-技术突破-产业转化-临床应用”的全链条研究特色；突破现有CT成像技术在时间分辨率、能谱分辨率、定量精准度和辐射剂量等方面的极限，降低对成像系统硬件性能的需求，简化临床工作流程；与多家知名医疗器械企业紧密合作，完成多项学术成果的产业转化，与多家知名医院深入合作，构建新型诊疗解决方案，完成多项临床应用研究。

083100-生物医学工程
081002-信号与信息处理

CT成像
医学人工智能
医学图像分析

1. 应用数学、物理、计算机领域知识，将CT物理和脑生理模型引入人工智能方法中，发展新型脑CT技术，解决脑成像及脑相关疾病诊疗中的关键问题；
2. 应用数学、物理、计算机领域知识，将CT物理和心脏生理模型引入人工智能方法中，发展新型心脏CT技术，解决心脏成像及心脏相关疾病诊疗中的关键问题；
3. 应用数学、物理、计算机领域知识，将CT物理模型引入人工智能方法中，发展新型能谱CT技术，解决能谱成像中的关键问题。

   

博士研究生

获美国威斯康星大学麦迪逊分校（University of Wisconsin-Madison）医学物理博士学位

2018年3月-2022年2月：美国威斯康星大学麦迪逊分校，医学物理，助理科学家

2022年3月-今：中国科学院深圳先进技术研究院，医工所，副研究员

   

[1] Chen, Guang-Hong, Li, Yinsheng. SYSTEM AND METHOD FOR MULTI-ARCHITECTURE COMPUTED TOMOGRAPHY PIPELINE. US: US20190251713(A1), 2019-08-15.

   

[1] J. Montoya, C. Zhang, Yinsheng Li, K. Li, G.-H. Chen. Reconstruction of three-dimensional tomographic patient models for radiation dose modulation in CT from two scout views using deep learning. Medical Physics[J]. 2022, 49(2): [2] Li, Yinsheng, Li, Ke, Garrett, John W, Chen, GuangHong, Bosmans, H, Zhao, W, Yu, L. Generation of virtual non-contrast (VNC) image from dual energy CT scans using deep learning. MEDICAL IMAGING 2021: PHYSICS OF MEDICAL IMAGINGnull. 2021, 11595: [3] John W Garrett, Yinsheng Li, Ke Li, GuangHong Chen. Reduced anatomical clutter in digital breast tomosynthesis with statistical iterative reconstruction. Medical physics. 2021, 45(5): 2009-2022, [4] Li, Yinsheng, CruzBastida, Juan Pablo, Li, Ke, Bushe, Daniel, Francois, Christopher, Lubner, Meghan, Chen, GuangHong, Chen, GH, Bosmans, H. Feasibility of Achieving Spectral CT Imaging from A Single KV Acquisition and Deep Learning Method. MEDICAL IMAGING 2020: PHYSICS OF MEDICAL IMAGINGnull. 2021, 11312: http://dx.doi.org/10.1117/12.2549611.
[5] Hayes, John W, Montoya, Juan, Budde, Adam, Zhang, Chengzhu, Li, Yinsheng, Li, Ke, Hsieh, Jiang, Chen, GuangHong. High Pitch Helical CT Reconstruction. IEEE TRANSACTIONS ON MEDICAL IMAGING[J]. 2021, 40(11): 3077-3088, [6] Zhang, Chengzhu, Li, Yinsheng, Chen, GuangHong. Accurate and robust sparse-view angle CT image reconstruction using deep learning and prior image constrained compressed sensing (DL-PICCS). MEDICAL PHYSICS[J]. 2021, 48(10): 5765-5781, http://dx.doi.org/10.1002/mp.15183.
[7] Li, Yinsheng, Garrett, John W, Li, Ke, Strother, Charles, Chen, GuangHong, Chen, GH, Bosmans, H. High Temporal Resolution Time-Resolved C-arm Cone-beam CT Imaging using a Multi-Sweep Data Acquisition Scheme. MEDICAL IMAGING 2020: PHYSICS OF MEDICAL IMAGINGnull. 2021, 11312: http://dx.doi.org/10.1117/12.2549602.
[8] K Li, Yinsheng Li, Z. Qi, J. Garrett, T Grist, G.-H. Chen. Quantitative Lung Perfusion Blood Volume Derived from Dual Energy CT Imaging. Medical Physics[J]. 2021, 48(11): [9] Yang Chen, Adam Budde, Ke Li, Yinsheng Li, Jiang Hsieh, GuangHong Chen. A platform-independent method to reduce CT truncation artifacts using discriminative dictionary representations. Medical physics. 2021, 44(1): 121-131, [10] Li, Yinsheng, Garrett, John W, Li, Ke, Strother, Charles, Chen, GuangHong. An Enhanced SMART-RECON Algorithm for Time-Resolved C-Arm Cone-Beam CT Imaging. IEEE TRANSACTIONS ON MEDICAL IMAGING[J]. 2020, 39(6): 1894-1905, [11] Yinsheng Li, Ke Li, Chengzhu Zhang, Juan Montoya, GuangHong Chen. Learning to Reconstruct Computed Tomography (CT) Images Directly from Sinogram Data under A Variety of Data Acquisition Conditions. IEEE transactions on medical imaging. 2019, 38(10): 2469-2481, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962902/.
[12] Li Yinsheng, Li Ke, Zhang Chengzhu, Montoya Juan, Chen GuangHong, Schmidt TG, Chen GH, Bosmans H. Image reconstruction from fully-truncated and sparsely-sampled line integrals using iCT-Net. MEDICAL IMAGING 2019: PHYSICS OF MEDICAL IMAGINGnull. 2019, 10948: [13] Wagner, Martin G, Hinshaw, J Louis, Li, Yinsheng, Szczykutowiz, Timothy P, Laeseke, Paul, Mistretta, Charles A, Lee, Fred T, Jr. Ultra-Low Radiation Dose CT Fluoroscopy for Percutaneous Interventions: A Porcine Feasibility Study. RADIOLOGY[J]. 2019, 291(1): 241-249, [14] Harvey, Evan Cary, Feng, Mang, Ji, Xu, Zhang, Ran, Li, Yinsheng, Chen, GuangHong, Li, Ke. Impacts of photon counting CT to maximum intensity projection (MIP) images of cerebral CT angiography: theoretical and experimental studies. PHYSICS IN MEDICINE AND BIOLOGY[J]. 2019, 64(18): 185015-185015, [15] Li, Yinsheng, Chen, GuangHong. An Empirical Data Inconsistency Metric (DIM) Driven CT Image Reconstruction Method. IEEE TRANSACTIONS ON MEDICAL IMAGING[J]. 2019, 38(2): 337-348, [16] Li, Yinsheng, Garrett, John W, Li, Ke, Wu, Yijing, Johnson, Kevin, Schafer, Sebastian, Strother, Charles, Chen, GuangHong. Time-resolved C-arm cone beam CT angiography (TR-CBCTA) imaging from a single short-scan C-arm cone beam CT acquisition with intra-arterial contrast injection. PHYSICS IN MEDICINE AND BIOLOGY[J]. 2018, 63(7): 075001-075001, https://www.webofscience.com/wos/woscc/full-record/WOS:000428263600001.
[17] Garrett, John W, Li, Yinsheng, Li, Ke, Wu, Yijing, Johnson, Kevin, Schafer, Sebastian, Chen, GuangHong. Quantification of temporal resolution improvement factor in SMART-RECON based time-resolved C-arm Cone beam computed tomography angiography (TR-CBCTA). PHYSICS IN MEDICINE AND BIOLOGY[J]. 2018, 63(19): https://www.webofscience.com/wos/woscc/full-record/WOS:000446205500001.
[18] Montoya, J C, Li, Y, Strother, C, Chen, G H. 3D Deep Learning Angiography (3D-DLA) from C-arm Conebeam CT. AMERICAN JOURNAL OF NEURORADIOLOGY[J]. 2018, 39(5): 916-922, http://dx.doi.org/10.3174/ajnr.A5597.
[19] Yinsheng Li, M Speidel, C Francois, G.-H. Chen. Radiation Dose Reduction in Dynamic CT Myocardial Perfusion Imaging Using SMART-RECON. IEEE TRANSACTIONS ON MEDICAL IMAGING[J]. 2017, 36(12): 2557-2568, [20] Li Yinsheng, Niu Kai, Li Ke, Schafer Sebastian, Royalty Kevin, Strother Charles, Chen GuangHong, Kontos D, Flohr TG, Lo JY. C-arm cone beam CT perfusion imaging using the SMART-RECON algorithm to improve temporal sampling density and temporal resolution. MEDICAL IMAGING 2016: PHYSICS OF MEDICAL IMAGINGnull. 2016, 9783: [21] Yinsheng Li, Kai Niu, Pengfei Yang, Beveley AagaardKienitz, David B Niemann, Azam S Ahmed, Charles Strother, GuangHong Chen. Mask free Intravenous 3D Digital Subtraction Angiography (IV 3D-DSA) from a single C-arm acquisition. Proceedings of SPIE--the International Society for Optical Engineering. 2016, 9783: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710838/.
[22] Yinsheng Li, John Garrett, GuangHong Chen. Reduction of Beam Hardening Artifacts in Cone-Beam CT Imaging via SMART-RECON Algorithm. Proceedings of SPIE--the International Society for Optical Engineering. 2016, 9783: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710817/.
[23] Bannas, Peter, Li, Yinsheng, Motosugi, Utaroh, Li, Ke, Lubner, Meghan, Chen, GuangHong, Pickhardt, Perry J. Prior Image Constrained Compressed Sensing Metal Artifact Reduction (PICCS-MAR): 2D and 3D Image Quality Improvement with Hip Prostheses at CT Colonography. EUROPEAN RADIOLOGY[J]. 2016, 26(7): 2039-2046, https://www.webofscience.com/wos/woscc/full-record/WOS:000377996200008.
[24] Chen, GuangHong, Li, Yinsheng. Synchronized multiartifact reduction with tomographic reconstruction (SMART-RECON): A statistical model based iterative image reconstruction method to eliminate limited-view artifacts and to mitigate the temporal-average artifacts in time-resolved CT. MEDICAL PHYSICS[J]. 2015, 42(8): 4698-4707, https://www.webofscience.com/wos/woscc/full-record/WOS:000358933000027.
[25] Li Yinsheng, Tang Jie, Chen GuangHong, Whiting BR, Hoeschen C, Kontos D. Impact of Norm Selections on the Performance of Four-dimensional Cone-beam Computed Tomography (4DCBCT) using PICCS. MEDICAL IMAGING 2014: PHYSICS OF MEDICAL IMAGINGnull. 2014, 9033: [26] Li Yinsheng, Tang Jie, Chen GuangHong, Nishikawa RM, Whiting BR, Hoeschen C. Impact of Norm Selections on the Performance of Prior Image Constrained Compressed Sensing (PICCS). MEDICAL IMAGING 2013: PHYSICS OF MEDICAL IMAGINGnull. 2013, 8668: [27] Li, Yinsheng, Chen, Yang, Hu, Yining, Oukili, Ahmed, Luo, Limin, Chen, Wufan, Toumoulin, Christine. Strategy of computed tomography sinogram inpainting based on sinusoid-like curve decomposition and eigenvector-guided interpolation. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION[J]. 2012, 29(1): 153-163, https://www.webofscience.com/wos/woscc/full-record/WOS:000299166000017.
[28] Chen, Yang, Li, Yinsheng, Guo, Hong, Hu, Yining, Luo, Limin, Yin, Xindao, Gu, Jianping, Toumoulin, Christine. CT Metal Artifact Reduction Method Based on Improved Image Segmentation and Sinogram In-Painting. MATHEMATICAL PROBLEMS IN ENGINEERING[J]. 2012, 2012: https://doaj.org/article/f6b31e796e034c5c8eccbb72acf28312.
[29] Chen, Yang, Li, Yinsheng, Yu, Weimin, Luo, Limin, Chen, Wufan, Toumoulin, Christine. JOINT-MAP TOMOGRAPHIC RECONSTRUCTION WITH PATCH SIMILARITY BASED MIXTURE PRIOR MODEL. MULTISCALE MODELING & SIMULATION[J]. 2011, 9(4): 1399-1419, https://www.webofscience.com/wos/woscc/full-record/WOS:000298366100005.
[30] Chen, Yang, Yu, Weimin, Li, Yinsheng, Yang, Zhou, Luo, Limin, Chen, Wufan. Bayesian Image Restoration Using a Large-Scale Total Patch Variation Prior. MATHEMATICAL PROBLEMS IN ENGINEERING[J]. 2011, 2011: https://doaj.org/article/25369d3acb4b4daebbff40e76e2308f7.
[31] Chen, Yang, Chen, Wufan, Yin, Xindao, Ye, Xianghua, Bao, Xudong, Luo, Limin, Feng, Qianjing, Li, Yinsheng, Yu, Xiaoe. Improving low-dose abdominal CT images by Weighted Intensity Averaging over Large-scale Neighborhoods. EUROPEAN JOURNAL OF RADIOLOGY[J]. 2011, 80(2): E42-E49, http://dx.doi.org/10.1016/j.ejrad.2010.07.003.
[32] Chen, Yang, Li, Yinsheng, Dong, Yingmei, Hao, Liwei, Luo, Limin, Chen, Wufan. Effective Image Restorations Using a Novel Spatial Adaptive Prior. EURASIP JOURNAL ON ADVANCES IN SIGNAL PROCESSING[J]. 2010, https://doaj.org/article/688f30832d114305b03a03605157a745.
[33] LiminLuo, YiningHu, XindaoYin, ChristineToumoulin, HongGuo, JianpingGu, YangChen, YinshengLi. CT Metal Artifact Reduction Method Based on Improved Image Segmentation and Sinogram In-Painting. Hindawi Publishing Corporation. http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201912140974861ZK.
[34] ZhouYang, LiminLuo, WufanChen, YangChen, WeiminYu, YinshengLi. Bayesian Image Restoration Using a Large-Scale Total Patch Variation Prior. Hindawi Publishing Corporation. http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201912140974166ZK.

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2019年-今：《Medical Physics》副主编

2020年-今：《American Journal of Neuroradiology》编委

2022年-今：《Frontiers in Radiology》客座主编