疾病标记物的传感分析

纳米酶的性能调控

   

070302-分析化学

化学与生物传感技术

2002-03--2005-03   中国科学院研究生院   博士生
1998-09--2001-07   华中师范大学   硕士生
1994-09--1998-07   曲阜师范大学   学士生

2006年9月－                            中国科学院大学化学科学学院         工作 

2013年1月-2014年1月            明尼苏达大学                                     访问学者 

2004年9月－2006年9月          清华大学化学系                                博士后

发表文章：      

1.  Dongxiao Li, Zhimin Guo, Ruihuan Zhao, Nan Yin, Qingling Xu*, Xin Yao*, simple method for the preparation of CeO₂ with high antioxidant activity and wide application range, Nanotechnology 34 (2023) 105706.
2.  Ruihuan Zhao, Dongxiao Li, Nan Yin, Zhimin Guo, Dengchao Wang,* Xin Yao*,The high sensitive and selective detection of dopamine based on its electropolymerization by electrochemical surface plasmon resonance, Sensors and Actuators: B. Chemical 370 (2022) 132401.
3. Ruihuan Zhao, Nan Yin, Lixin Ma, Jie Zhang, Yangkai Luo, Zhimin Guo, Mengmei Fa, Dingding Yang, Dengchao Wang, and Xin Yao^*，Surface Plasmon Resonance (SPR) Determination of Adenosine Triphosphate (ATP) Using Silver (I) induced Configuration Changes of a Single Stranded DNA Probe with Cytosine (C) Analytical Letters, 2022, 55, 18, 2954–2967.
4. Nan Yin, Ruihuan Zhao, Jie Zhang, Dingding Yang, Zhimin Guo, Rui Liu, Xin Yao^*，A lable-free SPR  biosensor based on one peptide sequence with three recognition sites for O-GlcNAc transferase detection，Talanta 2021,222,121664. 
5.  Mengmei Fa, Jie Zhang, Dingding Yang, Li Gao, Ruihuan Zhao, Yangkai Luo and Xin Yao*, Enhancement of antioxidant activity of welldispersed core–shell structured CeO₂ coating Au nanorods under visible light irradiation, Nanotechnology, 2020, 31, 235708.
6.  Yangkai Luo，Ruihuan Zhao，Mengmei Fa，Dingding Yang，Li Gao， Xin Yao*，The effect of the exposed crystal plane on the antioxidant activity of nanoceria，Ceram. Int.，2019, 45, 15, 8659-18665.
7.  Li Gao, Ruihuan Zhao, Yiwen Wang, Mei Lu, Dingding Yang, Mengmei Fa, Xin Yao*，Surface plasmon resonance biosensor for the accurate and sensitive quantification of O-GlcNAc based on cleavage by b-D-Nacetylglucosaminidase，Anal. Chim. Acta，2018,1014,90-98.  
8.   Mengmei Fa, Dingding Yang, Li Gao, Ruihuan Zhao, Yangkai Luo, Xin Yao*，The effect of AuNP modification on the antioxidant activity of CeO₂ nanomaterials with different morphologies, Appl. Surf. Sci, 2018, 457, 352-359.  
9.  Dingding Yang, Mengmei Fa, Li, Gao, Ruihuan Zhao, Yangkai Luo, Xin Yao*, The effect of  DNA on the oxidase  activity of  nanoceria with different mrphologies, Nanotechnology, 2018, 29, 385101.
10. Li Gao, Yiwen Wang, Mei Lu, Mengmei Fa, Dingding Yang and Xin Yao*，Simple method for O-GlcNAc sensitive detection based on graphene quantum dots，RSC Adv., 2017, 7, 31204–31211.
11.  Yiwen Wang, Fei Qin, Mei Lu, Li Gao, Xin Yao*，The screening and evaluating of chitosan/β-cyclodextrin nanoparticles for effective delivery mitoxantrone hydrochloride，Polymer Science, Series A, 2017，59(3),90-97.
12.  Mei Lu, Yan Zhang, Yiwen Wang, Miao Jiang, and Xin Yao*, Insight into several factors that affect the conversion between antioxidant and oxidant activities of nanoceria, ACS Appl. Mater. Interfaces, 2016, 8(36), 23580-23590.
13.  Yiwen Wang, Fei Qin, Haina Tan, Yan Zhang, Miao Jiang, Mei Lu, Xin Yao*, pH-Responsive glycol chitosan-crosslinked carboxymethyl–beta-cyclodextrin nanoparticles for controlled release of anticancer drugs, Int. J Nanomedicine, 2015, 10, 7359-7370.
14.  Yanwu Zhai, Yan Zhang, Fei Qin, and Xin Yao, An electrochemical DNA biosensor for evaluating the effect of mix anion in cellular fluid on the antioxidant activity of CeO₂ nanoparticles, Biosensors & Bioelectronics, 2015, 70,130-136.
15.  Xin Yao, Kairat Sabyrov, Todd Klein, R. Lee Penn, Timothy S. Wiedmann，Evaluation of magnetic heating of asymmetric magnetite Particles，Journal of Magnetism and Magnetic Materials, 2015,381,21-27.
16.     Yan Zhang, Kebin Zhou, Yanwu Zhai, Fei Qin, Lulu Pan and Xin Yao*，Crystal plane effects of nano-CeO₂ on its antioxidant activity，RSC Adv., 2014, 4, 50325–50330. 
17.     Yanwu Zhai Kebin Zhou, Ying Xue, Fei Qin, Limei Yang and Xin Yao*，Synthesis of water-soluble chitosan-coated nanoceria with excellent antioxidant properties，RSC Adv., 2013, 3, 6833–6838.
18.     Haina Tan, Fei Qin, Dongfeng Chen, Songbai Han, Wu Lu, Xin Yao*, Study of glycol chitosan-carboxymethyl β-cyclodextrins as anticancer drugs carrier, Carbohyd.  Polym., 2013, 93, 679-685.
19.   Haina Tan, Ying Xue, Qingfen Luan and Xin Yao*，Evaluation of glycol chitosan-graft-carboxymethyl β-cyclodextrin as potential pH-sensitive anticancer drug carrier by surface plasmon resonance, Analytical Methods, 2012,4（9）,2784-2790.
20.  Ying Xue, Yanwu Zhai, Kebin Zhou, Lei Wang, Haina Tan, Qingfen Luan, Xin Yao*，The vital role of the buffer anions in the antioxidant activity of CeO2 nanoparticles, Chem. Eur. J., 2012,18(35),11115-11122.
21.  Ying Xue, Qingfen Luan, Dan Yang, Xin Yao*, and Kebin Zhou*，Direct evidence for hydroxyl radical scavenging activity of cerium oxide nanoparticles，J. Phys. Chem. C, 2011, 115,4433-4438.
22.  Qingfen Luan, Kebin Zhou, Haina Tan, Dan Yang, Xin Yao*, Au-NPs enhanced SPR biosensor based on hairpin DNA without the effect of nonspecific adsorption, Biosens. Bioelectron., 2011, 26(5), 2473–2477.
23.   Qingfen Luan, Ying Xue, Xin Yao^*, Wu Lu, Hairpin DNA probe based surface plasmon resonance biosensor used for the activity assay of E. coli DNA ligase, Analyst, 2010,135, 414-418.
24.  Qingfen Luan, Ying Xue, Xin Yao*, A simple hairpin DNA sensor for label-free detection of sub-attomole DNA target, Sens. and Actuators B, 2010,147,561–565.
25.   Qingfen Luan, Jun Li, Xin Yao*, Fabrication of Fe(CN)₆^3- functionalized PDDA/CdTe layer-by-layer film with good electron transfer ability, Electroanalysis, 2009,21(16), 1799-1804.
26.  Xiaoling Xiao, Qingfen Luan, Xin Yao^*, Kebin Zhou^*, Single-crystal CeO2 nanocubes used for the direct electron transfer and electrocatalysis of horseradish peroxidase, Biosens. Bioelectron., 2009,24,2447-2451.

已指导学生

栾庆芬  硕士研究生  070302-分析化学  

薛颖  硕士研究生  070302-分析化学  

谭海娜  硕士研究生  070302-分析化学  

翟艳五  硕士研究生  070302-分析化学  

秦飞  硕士研究生  070302-分析化学  

姜淼  硕士研究生  085204-材料工程  

张彦  硕士研究生  085216-化学工程  

王艺文  硕士研究生  070302-分析化学  

卢梅  硕士研究生  085216-化学工程  

高利  硕士研究生  070302-分析化学  

现指导学生

法孟梅  硕士研究生  070302-分析化学  

杨丁丁  硕士研究生  070302-分析化学  

赵瑞欢  硕士研究生  070302-分析化学  

罗炀凯  硕士研究生  070302-分析化学  

殷楠  硕士研究生  085216-化学工程  

张杰  硕士研究生  085216-化学工程