发表论文
[1] Ting Wang, Jie Guo, Liping Li, Qiuzhu Jin, Fuping Zhang, Baidong Hou, Yan Zhang, Xuyu Zhou. The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory Tcells. CELL REPORTS[J]. 2024, 第 8 作者 通讯作者 43(5): 114222, https://doaj.org/article/b1f3d5bc500d41e5867961e5037e6770.[2] Xiping Zhu, Sheng Hong, Jiachen Bu, Yingping Liu, Can Liu, Runhan Li, Tiantian Zhang, Zhuqiang Zhang, Liping Li, Xuyu Zhou, Zhaolin Hua, Bing Zhu, Baidong Hou. Antiviral memory B cells exhibit enhanced innate immune response facilitated by epigenetic memory. Science Advances[J]. 2024, 第 10 作者null(null): [3] Mengyu Zhang, Wei Xu, Lingjie Luo, Fenghui Guan, Xiangyao Wang, Pei Zhu, Jianhua Zhang, Xuyu Zhou, Feng Wang, Sheng Ye. Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. COMMUNICATIONS BIOLOGY. 2024, 第 8 作者7(1): http://dx.doi.org/10.1038/s42003-024-06209-2.[4] Wei, Xundong, Zhang, Jianhua, Cui, Jian, Xu, Wei, Zhao, Gang, Guo, Chang, Yuan, Wei, Zhou, Xuyu, Ma, Jie. Adaptive plasticity of natural interleukin-35-induced regulatory T cells (Tr35) that are required for T-cell immune regulation. THERANOSTICS[J]. 2024, 第 8 作者 通讯作者 14(7): 2897-2914, http://dx.doi.org/10.7150/thno.90608.[5] Qianchong Gu, Xiufeng Zhao, Jie Guo, Qiuzhu Jin, Ting Wang, Wei Xu, Liping Li, Jianhua Zhang, Wei Zhang, Sheng Hong, Fuping Zhang, Baidong Hou, Xuyu Zhou. The splicing isoform Foxp3Δ2 differentially regulates tTreg and pTreg homeostasis. CELL REPORTS[J]. 2023, 第 13 作者 通讯作者 42(8): 112877, https://doaj.org/article/4aa7baaff9ca4a82b02d839b82009c02.[6] Gao, Ping, Liu, Hongtao, Huang, Huarong, Sun, Yu, Jia, Baoqian, Hou, Baidong, Zhou, Xuyu, Strober, Warren, Zhang, Fuping. The Crohn Disease-associated ATG16L1(T300A) polymorphism regulates inflammatory responses by modulating TLR- and NLR-mediated signaling. AUTOPHAGY[J]. 2022, 第 7 作者2561-2575, http://dx.doi.org/10.1080/15548627.2022.2039991.[7] Xuyu Zhou, Jingxian Zhao, Bin Li, Xuguang Tai. Editorial: Revisit the roles of regulatory T cells in infection. Frontiers in Immunology[J]. 2022, 第 1 作者 通讯作者 [8] Ping Gao, Miao Ji, Xinyuan Liu, Xiaotong Chen, Hongtao Liu, Shihua Li, Baoqian Jia, Chao Li, Lili Ren, Xin Zhao, Qihui Wang, Yuhai Bi, Xu Tan, Baidong Hou, Xuyu Zhou, Wenjie Tan, Tao Deng, Jianwei Wang, George Fu Gao, Fuping Zhang. Apolipoprotein E mediates cell resistance to influenza virus infection. SCIENCE ADVANCES[J]. 2022, 第 15 作者8(38): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491715/.[9] Wei, Xundong, Zhang, Jianhua, Cui, Jian, Xu, Wei, Zhou, Xuyu, Ma, Jie. A Split-Cre system designed to detect simultaneous expression of two genes based on SpyTag/SpyCatcher conjugation and Split-GFP dimerization. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2021, 第 5 作者 通讯作者 297(4): [10] Zhou, Xuyu, Lu, LiFan. Editorial: Regulators of a Regulator: Post-Transcriptional Regulation in Tregs. FRONTIERS IN IMMUNOLOGY[J]. 2021, 第 1 作者 通讯作者 12: http://dx.doi.org/10.3389/fimmu.2021.699911.[11] Wei, Xundong, Zhang, Jianhua, Zhou, Xuyu. Ex-TFRs: A Missing Piece of the SLE Puzzle?. FRONTIERS IN IMMUNOLOGY[J]. 2021, 第 3 作者 通讯作者 12: [12] Zhao, Ruozhu, Chen, Xin, Ma, Weiwei, Zhang, Jinyu, Guo, Jie, Zhong, Xiu, Yao, Jiacheng, Sun, Jiahui, Rubinfien, Julian, Zhou, Xuyu, Wang, Jianbin, Qi, Hai. A GPR174-CCL21 module imparts sexual dimorphism to humoral immunity. NATURE[J]. 2020, 第 10 作者577(7790): 416-+, http://dx.doi.org/10.1038/s41586-019-1873-0.[13] Li, Mingyang, Zhao, Weijia, Wang, Yifan, Jin, Lixue, Jin, Gaowen, Sun, Xiuyuan, Wang, Wei, Wang, Ke, Xu, Xi, Hao, Jie, Jin, Rong, Fu, Wenxian, Sun, Ying, Chang, Yingjun, Huang, Xiaojun, Zhou, Xuyu, Wu, Hounan, Zhang, Kunshan, Ge, Qing. A wave of Foxp3(+) regulatory T cell accumulation in the neonatal liver plays unique roles in maintaining self-tolerance. CELLULAR & MOLECULAR IMMUNOLOGY[J]. 2020, 第 16 作者17(5): 507-518, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193579/.[14] Hays, Aislinn, Duan, Xingyu, Zhu, Jianxin, Zhou, Wei, Upadhyayula, Satya, Shivde, Juili, Song, Li, Wang, Huizhi, Su, Li, Zhou, Xuyu, Liang, Shuang. Down-regulated Treg cells in exacerbated periodontal disease during pregnancy. INTERNATIONAL IMMUNOPHARMACOLOGY[J]. 2019, 第 10 作者69: 299-306, http://dx.doi.org/10.1016/j.intimp.2019.01.031.[15] Zhu, Xueping, Zhang, Wei, Guo, Jie, Zhang, Xuejie, Li, Liping, Wang, Ting, Yan, Jinghua, Zhang, Fuping, Hou, Baidong, Gao, Ning, Gao, George F, Zhou, Xuyu. Noc4L-Mediated Ribosome Biogenesis Controls Activation of Regulatory and Conventional T Cells. CELL REPORTS[J]. 2019, 第 12 作者 通讯作者 27(4): 1205-+, http://dx.doi.org/10.1016/j.celrep.2019.03.083.[16] Zhang, Zhongmei, Zhou, Xuyu. Foxp3 Instability Helps tTregs Distinguish Self and Non-self. FRONTIERS IN IMMUNOLOGY[J]. 2019, 第 2 作者 通讯作者 10: https://doaj.org/article/90b8fa4f7ea64b3592ab7cca915e7d3f.[17] Hong, Sheng, Zhang, Zhimin, Liu, Hongtao, Tian, Meijie, Zhu, Xiping, Zhang, Zhuqiang, Wang, Weihong, Zhou, Xuyu, Zhang, Fuping, Ge, Qing, Zhu, Bing, Tang, Hong, Hua, Zhaolin, Hou, Baidong. B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4(+) T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen. IMMUNITY[J]. 2018, 第 8 作者49(4): 695-+, http://dx.doi.org/10.1016/j.immuni.2018.08.012.[18] Tian, Meijie, Hua, Zhaolin, Hong, Sheng, Zhang, Zhimin, Liu, Can, Lin, Lin, Chen, Jiaorong, Zhang, Wei, Zhou, Xuyu, Zhang, Fuping, DeFranco, Anthony L, Hou, Baidong. B Cell-Intrinsic MyD88 Signaling Promotes Initial Cell Proliferation and Differentiation To Enhance the Germinal Center Response to a Virus-like Particle. JOURNAL OF IMMUNOLOGY[J]. 2018, 第 9 作者200(3): 937-948, https://www.webofscience.com/wos/woscc/full-record/WOS:000423124400007.[19] Zhou, Xuyu. Noc4L dictates Treg activation in vivo. JOURNAL OF IMMUNOLOGY. 2018, 第 1 作者200(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000459977701019.[20] Phiwpan, Krung, Zhou, Xuyu. MicroRNAs in regulatory T cells. CANCER LETTERS. 2018, 第 2 作者 通讯作者 423: 80-85, http://dx.doi.org/10.1016/j.canlet.2018.03.012.[21] Zhou Xuyu. Activation and Functional Specialization of Regulatory T Cells Lead to the Generation of Foxp3 Instability Article. The Journal of Immunology. 2017, 第 1 作者 通讯作者 [22] Wei, Xundong, Zhang, Jianhua, Gu, Qianchong, Huang, Man, Zhang, Wei, Guo, Jie, Zhou, Xuyu. Reciprocal Expression of IL-35 and IL-10 Defines Two Distinct Effector Treg Subsets that Are Required for Maintenance of Immune Tolerance. CELL REPORTS[J]. 2017, 第 7 作者 通讯作者 21(7): 1853-1869, http://dx.doi.org/10.1016/j.celrep.2017.10.090.[23] Kong, Decong, Chen, Zhe, Wang, Junping, Lv, Qingyu, Jiang, Hua, Zheng, Yuling, Xu, Maokai, Zhou, Xuyu, Hao, Huaijie, Jiang, Yongqiang. Interaction of factor H-binding protein of Streptococcus suis with globotriaosylceramide promotes the development of meningitis. VIRULENCE[J]. 2017, 第 8 作者 通讯作者 8(7): 1290-1302, https://www.webofscience.com/wos/woscc/full-record/WOS:000416969700035.[24] Zhang, Zhongmei, Zhang, Wei, Guo, Jie, Gu, Qianchong, Zhu, Xueping, Zhou, Xuyu. Activation and Functional Specialization of Regulatory T Cells Lead to the Generation of Foxp3 Instability. JOURNAL OF IMMUNOLOGY[J]. 2017, 第 6 作者 通讯作者 198(7): 2612-2625, https://www.webofscience.com/wos/woscc/full-record/WOS:000397611900011.[25] Hu, Tanyu, Phiwpan, Krung, Guo, Jitao, Zhang, Wei, Guo, Jie, Zhang, Zhongmei, Zou, Mangge, Zhang, Xuejie, Zhang, Jianhua, Zhou, Xuyu. MicroRNA-142-3p Negatively Regulates Canonical Wnt Signaling Pathway. PLOS ONE[J]. 2016, 第 10 作者 通讯作者 11(6): https://doaj.org/article/65483ee34dfc4e9dad3ccda571949fa5.[26] Huang, Man, Zhang, Wei, Guo, Jie, Wei, Xundong, Phiwpan, Krung, Zhang, Jianhua, Zhou, Xuyu. Improved Transgenic Mouse Model for Studying HLA Class I Antigen Presentation. SCIENTIFIC REPORTS[J]. 2016, 第 7 作者 通讯作者 6: http://dx.doi.org/10.1038/srep33612.[27] Tong, Yaojun, Liu, Mei, Zhang, Yu, Liu, Xueting, Huang, Ren, Song, Fuhang, Dai, Huanqin, Ren, Biao, Sun, Nuo, Pei, Gang, Bian, Jiang, Jia, XinMing, Huang, Guanghua, Zhou, Xuyu, Li, Shaojie, Zhang, Buchang, Fukuda, Takashi, Tomoda, Hiroshi, Omura, Satoshi, Cannon, Richard D, Calderone, Richard, Zhang, Lixin. Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters. SYNTHETIC AND SYSTEMS BIOTECHNOLOGY[J]. 2016, 第 14 作者1(3): 158-168, http://lib.cqvip.com/Qikan/Article/Detail?id=7103844692.[28] Jitao Guo Xuyu Zhou. Regulatory T cells turn pathogenic. 中国免疫学杂志:英文版[J]. 2015, 525-532, http://lib.cqvip.com/Qikan/Article/Detail?id=666249268.[29] Guo, Jitao, Zhou, Xuyu. Regulatory T cells turn pathogenic. CELLULAR & MOLECULAR IMMUNOLOGY[J]. 2015, 第 2 作者 通讯作者 12(5): 525-532, http://lib.cqvip.com/Qikan/Article/Detail?id=666249268.[30] Phiwpan, Krung, Guo, Jie, Zhang, Wei, Hu, Tanyu, Boruah, Bhargavi M, Zhang, Jianhua, Zhou, Xuyu. A Novel Transgenic Mouse Line for Tracing MicroRNA-155-5p Activity In Vivo. PLOS ONE[J]. 2015, 第 7 作者 通讯作者 10(6): https://www.webofscience.com/wos/woscc/full-record/WOS:000356630900123.[31] Pan, Xuwen, Ding, Huiguo, Zhou, Xuyu, Tien, Po. Identification of hepatitis B virus-specific CTL epitopes presented by HLA-A*33:03 in peripheral blood mononuclear cells from patients and transgenic mice. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2014, 第 3 作者449(1): 135-140, https://www.webofscience.com/wos/woscc/full-record/WOS:000337990700023.[32] 张雪洁, 张建华, 张伟, 郭洁, 周旭宇, , , , , , . 小鼠T-bet逆转录病毒载体的构建与功能验证. 生物工程学报[J]. 2014, 第 5 作者30(10): 1586-1593, https://cjb.ijournals.cn/cjbcn/article/abstract/gc14101586?st=article_issue.[33] Zhou, Xuyu. Sustained PI3K activation destabilized tTreg. JOURNAL OF IMMUNOLOGY. 2014, 第 1 作者192: https://www.webofscience.com/wos/woscc/full-record/WOS:000209765003005.[34] Zhou Xuyu. Suilysin remodels the cytoskeletons of human brain microvascular endothelial cells by activation RhoA and Rac1 GTPase. Protein and Cell. 2014, 第 1 作者 通讯作者 [35] Guo, Jitao, Zhang, Jianhua, Zhang, Xuejie, Zhang, Zhongmei, Wei, Xundong, Zhou, Xuyu. Constitutive Activation of MEK1 Promotes Treg Cell Instability in Vivo. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2014, 第 6 作者 通讯作者 289(51): 35139-35148, http://dx.doi.org/10.1074/jbc.M114.589192.[36] Peipei Liu, Di Liu, Xi Yang, Jing Gao, Yan Chen, Xue Xiao, Fei Liu, Jing Zou, Jun Wu, Juncai Ma, Fangqing Zhao, Xuyu Zhou, George F Gao, Baoli Zhu. Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains. 蛋白质与细胞[J]. 2014, 第 12 作者5(8): 603-615, https://journal.hep.com.cn/pac/CN/10.1007/s13238-014-0060-1.[37] Liu, Peipei, Liu, Di, Yang, Xi, Gao, Jing, Chen, Yan, Xiao, Xue, Liu, Fei, Zou, Jing, Wu, Jun, Ma, Juncai, Zhao, Fangqing, Zhou, Xuyu, Gao, George F, Zhu, Baoli. Characterization of human alpha beta TCR repertoire and discovery of D-D fusion in TCR beta chains. PROTEIN & CELL[J]. 2014, 第 12 作者5(8): 603-615, https://www.webofscience.com/wos/woscc/full-record/WOS:000340566500004.[38] Stumpf, Melanie, Zhou, Xuyu, Chikuma, Shunsuke, Bluestone, Jeffrey A. Tyrosine 201 of the cytoplasmic tail of CTLA-4 critically affects T regulatory cell suppressive function. EUROPEAN JOURNAL OF IMMUNOLOGY[J]. 2014, 第 2 作者44(6): 1737-1746, https://www.webofscience.com/wos/woscc/full-record/WOS:000337531200018.[39] Lv, Qingyu, Hao, Huaijie, Bi, Lili, Zheng, Yuling, Zhou, Xuyu, Jiang, Yongqiang. Suilysin remodels the cytoskeletons of human brain microvascular endothelial cells by activating RhoA and Rac1 GTPase. PROTEIN & CELL[J]. 2014, 第 5 作者 通讯作者 5(4): 261-264, https://www.webofscience.com/wos/woscc/full-record/WOS:000334428400004.[40] Hao, Huaijie, Hui, Wenjia, Liu, Peng, Lv, Qingyu, Zeng, Xiaotao, Jiang, Hua, Wang, Yanzi, Zheng, Xin, Zheng, Yuling, Li, Jianchun, Zhou, Xuyu, Jiang, Yongqiang. Effect of Licochalcone A on Growth and Properties of Streptococcus suis. PLOS ONE[J]. 2013, 第 11 作者8(7): https://doaj.org/article/46a709cb25864d0fb0504d049ccf3cf2.[41] Li, Xinghui, Liu, Zhen, Yan, Xiaoli, Zhang, Xiaojun, Li, Yang, Zhao, Bao, Wang, Shengdian, Zhou, Xuyu, Gao, George F, Meng, Songdong. Induction of Regulatory T Cells by High-Dose gp96 Suppresses Murine Liver Immune Hyperactivation. PLOS ONE[J]. 2013, 第 8 作者8(7): https://doaj.org/article/17ebb4e46790479abee023d23227ea27.[42] BaileyBucktrout, Samantha L, MartinezLlordella, Marc, Zhou, Xuyu, Anthony, Bryan, Rosenthal, Wendy, Luche, Herve, Fehling, Hans J, Bluestone, Jeffrey A. Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response. IMMUNITY[J]. 2013, 第 3 作者39(5): 949-962, http://dx.doi.org/10.1016/j.immuni.2013.10.016.[43] Jeker, Lukas T, Zhou, Xuyu, Blelloch, Robert, Bluestone, Jeffrey A. DGCR8-Mediated Production of Canonical Micrornas Is Critical for Regulatory T Cell Function and Stability. PLOS ONE[J]. 2013, 第 2 作者8(5): https://doaj.org/article/27cdf87f5e5e4b56894ceef77ffbff91.[44] Jeker, Lukas T, Zhou, Xuyu, Gershberg, Kseniya, de Kouchkovsky, Dimitri, Morar, Malika M, Stadthagen, Gustavo, Lund, Anders H, Bluestone, Jeffrey A. MicroRNA 10a Marks Regulatory T Cells. PLOS ONE[J]. 2012, 第 2 作者7(5): https://www.webofscience.com/wos/woscc/full-record/WOS:000305343500023.[45] Zhang, Jianhua, Chen, Yong, Qi, Jianxun, Gao, Feng, Liu, Yanjie, Liu, Jun, Zhou, Xuyu, Kaufman, Jim, Xia, Chun, Gao, George F. Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens. JOURNAL OF IMMUNOLOGY[J]. 2012, 第 7 作者189(9): 4478-4487, http://www.irgrid.ac.cn/handle/1471x/756866.[46] Zhou, Xuyu, BaileyBucktrout, Samantha L, Jeker, Lukas T, Penaranda, Cristina, MartinezLlordella, Marc, Ashby, Meredith, Nakayama, Maki, Rosenthal, Wendy, Bluestone, Jeffrey A. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. NATURE IMMUNOLOGY[J]. 2009, 第 1 作者10(9): 1000-U104, http://dx.doi.org/10.1038/ni.1774.[47] Zhou, Xuyu, BaileyBucktrout, Samantha, Jeker, Lukas T, Bluestone, Jeffrey A. Plasticity of CD4(+) FoxP3(+) T cells. CURRENT OPINION IN IMMUNOLOGY. 2009, 第 1 作者21(3): 281-285, http://dx.doi.org/10.1016/j.coi.2009.05.007.[48] Zhou Xuyu. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ Tregs. The Journal of Experimental Medicine. 2006, 第 1 作者[49] Zhou, XY, YashiroOhtani, Y, Nakahira, M, Park, WR, Abe, R, Hamaoka, T, Naramura, M, Gu, H, Fujiwara, H. Molecular mechanisms underlying differential contribution of CD28 versus non-CD28 costimulatory molecules to IL-2 promoter activation. JOURNAL OF IMMUNOLOGY[J]. 2002, 168(8): 3847-3854, [50] XuYu Zhou, Kazuhito Toyooka, Toshiyuki Hamaoka, Yumi YashiroOhtani, XuGuang Tai, CheungSeog Park, Hiromi Fujiwara. CD5 Costimulation Up-Regulates the Signaling to Extracellular Signal-Regulated Kinase Activation in CD4+CD8+ Thymocytes and Supports Their Differentiation to the CD4 Lineage. AMERICAN ASSOCIATION OF IMMUNOLOGISTS. 2000, 第 1 作者http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201902028052689ZK.[51] Stumpf Melanie, Zhou Xuyu, Bluestone Jeffrey A.. The B7-independent isoform of CTLA-4 functions to regulate autoimmune diabetes. JOURNAL OF IMMUNOLOGY (BALTIMORE, MD. : 1950). 第 2 作者190(3): 961-969, [52] Zhou Xuyu, Jeker Lukas T., Fife Brian T., Zhu Shirley, Anderson Mark S., McManus Michael T., Bluestone Jeffrey A.. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. THE JOURNAL OF EXPERIMENTAL MEDICINE. 第 1 作者205(9): 1983-1991,